Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Clinical Centers (Collaborative U01) | Apply Online

Opportunity Summary:

The grant opportunity titled "Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Clinical Centers (Collaborative U01)" is a National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) designed to extend the work of the existing Teen LABS Consortium. It is explicitly a limited competition, meaning it is not broadly open to new clinical sites in the way many NIH announcements are. Instead, it invites an application in the cooperative agreement (U01) mechanism from the Teen LABS Clinical Centers themselves, with the main goal of continuing and expanding longitudinal follow-up of adolescents who previously enrolled in Teen LABS and underwent bariatric surgery. The underlying public health and scientific premise is that adolescent bariatric surgery raises important long-term questions about safety, sustained weight and metabolic outcomes, nutritional status, comorbidity resolution, psychosocial effects, and potential late complications, and those questions can only be answered well through structured, multi-year follow-up of an already-characterized cohort.

This FOA (Funding Opportunity Number RFA-DK-15-508) supports continuation of the Teen LABS Clinical Centers specifically, while a companion announcement (RFA-DK-15-509) is referenced as supporting continuation of the Teen LABS Biostatistics Research Center. That split is important because it signals a coordinated, consortium-style continuation: the clinical sites remain responsible for participant tracking, follow-up visits, clinical assessments, and data collection, while the biostatistics and data coordination functions are maintained under a separate award. Because the mechanism is a U01 cooperative agreement, NIH expects to have substantial programmatic involvement compared with a traditional investigator-initiated grant. In practical terms, that usually means NIH staff help guide major consortium decisions, facilitate harmonization across sites, and ensure the project stays aligned with the overall Teen LABS objectives and protocols, while the awardees maintain responsibility for the day-to-day conduct of the work.

From a program classification standpoint, the opportunity is listed under the Funding Activity Category of Food and Nutrition/Health and is associated with CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), which aligns with the Institute-level interest in obesity, metabolic disease, and digestive and kidney outcomes that can be affected by bariatric procedures. The announcement anticipated a single award (Expected Awards: 1) with an estimated total funding level of $2,000,000. No cost sharing or matching requirement was indicated, which is typical for many NIH research awards and removes the need for applicants to bring non-federal matching funds as a condition of the award.

The timing details reflect that this was a time-limited opportunity cycle. It was posted and created on July 20, 2015, had an original and current closing date of November 10, 2015, and an archive date of December 11, 2015. Those dates matter mainly for historical context now, but they also reflect that NIH set a single, specific window for the continuation application(s), consistent with how limited competitions and consortium continuations are often handled.

Eligibility is presented broadly in the general listing, including many categories of domestic organizations and governments (for example, nonprofits with and without 501(c)(3) status, public and private institutions of higher education, small businesses, for-profit organizations other than small businesses, and various local, county, state, tribal, and special district governments). The listing also names several institution types that NIH often highlights to clarify inclusion, such as Hispanic-serving institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, and Alaska Native and Native Hawaiian Serving Institutions, along with faith-based and community-based organizations and eligible federal agencies. However, the most important practical eligibility constraint is embedded in the FOA description itself: it is a limited competition inviting an application from the Clinical Centers for the Teen LABS Consortium. So even though many organizational types might be eligible in a general sense, the intent is continuation funding for the existing Teen LABS clinical infrastructure rather than an open solicitation for unrelated groups to propose new, independent bariatric surgery cohorts.

The FOA also makes clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. This points to NIH’s intent to keep all performance, oversight, and participant follow-up within U.S.-based institutions and settings for this particular continuation.

For applicants and stakeholders looking for the full text, NIH provided an Additional Information link to the FOA on the NIH grants guide website (http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-508.html). For technical access issues rather than scientific questions, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is consistent with NIH practice for troubleshooting broken links or difficulties retrieving the online announcement.

In short, RFA-DK-15-508 was a targeted NIH continuation opportunity using a cooperative agreement model to extend long-term follow-up of adolescents enrolled in the Teen LABS bariatric surgery cohort, maintaining the clinical site activities under this FOA while coordinating with a separately funded biostatistics center under a companion FOA.

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