Opportunity Information: Apply for RFA DK 09 506

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the Adult Acute Liver Failure Study Group (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jan 7, 2010 and posted on Jan 7, 2010.
  • Applicants must submit their applications by Mar 15, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $600,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education.
Apply for RFA DK 09 506

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Opportunity Summary:

This grant opportunity, titled "Limited Competition for the Continuation of the Adult Acute Liver Failure Study Group (U01)," is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The main goal is to support a competing continuation of the Adult Acute Liver Failure Study Group, meaning it is intended to keep an existing, established research effort going rather than launch an entirely new program. The emphasis on "limited competition" signals that eligibility to apply is restricted compared to an open NIH competition, typically because the work is viewed as a continuation of a specific ongoing consortium or coordinated research infrastructure that NIH wants to maintain without broadly recompeting it across all possible applicants.

The award uses the NIH cooperative agreement mechanism, specifically the U01. A U01 is different from a standard research project grant because it is designed for situations where NIH expects to have substantial scientific or programmatic involvement during the project. In practice, that generally means the funded group and NIH staff work closely together on elements such as study coordination, protocol development, data standards, milestone tracking, and overall governance. This structure fits large, multi-site clinical research networks and study groups, where maintaining consistent operations, shared data systems, and coordinated decision-making is essential.

NIDDK anticipated making one award under this announcement, with an estimated total of 10,000,000 in funding. The source data also lists an award ceiling of 600,000, which typically reflects a per-year cap or a budget limitation tied to a specific budget period, while the 10 million figure represents the expected total commitment across the full project period. Taken together, the numbers indicate a sizeable, multi-year investment aimed at sustaining the infrastructure and coordinated activities of the Adult Acute Liver Failure Study Group rather than funding a collection of unrelated individual projects.

The opportunity is categorized as discretionary and is associated with a health-related funding activity area, with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). There is no cost sharing or matching requirement, so applicants are not required to contribute non-federal funds as a condition of the award. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, which aligns with the typical institutional base for NIH-supported clinical research consortia and coordinating centers.

Key administrative dates show that the announcement was posted on January 7, 2010, with an application due date (original and current closing date) of March 15, 2010. The archive date is April 15, 2010, meaning it was subsequently closed and stored as a past opportunity. Additional details and the full announcement were made available through the NIH grants guide page linked in the opportunity record. For technical issues accessing the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster via FBOWebmaster@OD.NIH.GOV, which is a support contact for access and linking problems rather than a scientific or grants management program contact.

Overall, this FOA represents a targeted NIH investment to continue a coordinated adult acute liver failure research group under a cooperative agreement framework, with a single expected award and a large total funding level intended to sustain and advance the network's collaborative research activities.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The funding announcement is titled "Limited Competition for the Continuation of the Adult Acute Liver Failure Study Group (U01)."

Which agency and institute are offering this opportunity?

This is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What is the main purpose of this funding announcement?

The main goal is to support a competing continuation of the Adult Acute Liver Failure Study Group. It is intended to continue an existing, established research effort rather than start an entirely new program.

What does "limited competition" mean in this context?

"Limited competition" indicates that eligibility to apply is restricted compared to an open NIH competition. This is typically used when NIH is continuing a specific ongoing consortium or coordinated research infrastructure that it wants to maintain, rather than broadly recompeting it across all possible applicants.

What NIH funding mechanism is used for this award?

The award uses the NIH cooperative agreement mechanism, specifically a U01.

How is a U01 cooperative agreement different from a standard NIH research grant?

A U01 is designed for situations where NIH expects substantial scientific or programmatic involvement during the project. In practice, this generally means the funded group and NIH staff work closely together on areas such as study coordination, protocol development, data standards, milestone tracking, and overall governance.

What types of research efforts does a U01 typically support?

This structure is commonly used for large, multi-site clinical research networks and study groups where consistent operations, shared data systems, and coordinated decision-making are essential.

How many awards did NIDDK anticipate making under this announcement?

NIDDK anticipated making one award under this funding announcement.

What is the estimated total funding level for this opportunity?

The announcement lists an estimated total of 10,000,000 in funding, reflecting the expected total commitment across the full project period.

What is the award ceiling of 600,000 and how does it relate to the total funding amount?

The source data lists an award ceiling of 600,000, which typically reflects a per-year cap or a budget limitation tied to a specific budget period. The 10,000,000 figure represents the anticipated total commitment across the full project period. Together, these numbers suggest a sizable multi-year investment.

Is this opportunity intended to fund multiple unrelated projects?

No. The described funding levels and the continuation focus indicate the investment is aimed at sustaining the infrastructure and coordinated activities of the Adult Acute Liver Failure Study Group rather than funding unrelated individual projects.

What is the funding activity area associated with this opportunity?

The opportunity is associated with a health-related funding activity area.

What is the CFDA number listed for this opportunity?

The CFDA number is 93.847, labeled as Diabetes, Digestive, and Kidney Diseases Extramural Research.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.

Which types of organizations are eligible to apply?

Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.

When was the funding announcement posted?

The announcement was posted on January 7, 2010.

What was the application due date?

The application due date (original and current closing date) was March 15, 2010.

Is this opportunity still open?

No. The archive date is April 15, 2010, indicating the opportunity was closed and stored as a past opportunity.

Where were additional details and the full announcement provided?

Additional details and the full announcement were made available through the NIH grants guide page linked in the opportunity record.

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

Is the listed email contact a scientific or grants management contact?

No. The provided contact is described as a support contact for access and linking problems rather than a scientific or grants management program contact.

How would you summarize this funding opportunity in plain terms?

This FOA represents a targeted NIH investment to continue a coordinated adult acute liver failure research group under a cooperative agreement (U01) framework, with one expected award and a large total funding level intended to sustain and advance the study group's collaborative research activities.

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Previous opportunity: Limited Competition for the Continuation of the Pediatric Acute Liver Failure Study Group (U01)

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