Opportunity Information: Apply for RFA DK 09 505

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the Pediatric Acute Liver Failure Study Group (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jan 7, 2010 and posted on Jan 7, 2010.
  • Applicants must submit their applications by Mar 15, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $17,100,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $700,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education.
Apply for RFA DK 09 505

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Opportunity Summary:

This grant opportunity, titled "Limited Competition for the Continuation of the Pediatric Acute Liver Failure Study Group (U01)," is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its central goal is to support a competing continuation of the Pediatric Acute Liver Failure Study Group, meaning the program is intended to keep an existing, organized research effort operating and advancing rather than launching an entirely new, unrelated project. The scientific focus is pediatric acute liver failure, a severe and often rapidly progressing condition in children where coordinated, multi-site clinical research and shared data resources are typically necessary to improve understanding, diagnosis, management, and outcomes.

The award uses the NIH Cooperative Agreement mechanism (U01). In practical terms, a U01 is different from a standard research project grant because it is designed for situations where the NIH expects to have substantial involvement in the activity. The funded group generally conducts the work, but NIH program staff play an active partnership role through oversight, coordination, and collaboration to help guide the project toward agreed-upon milestones and objectives. This structure is commonly used for research networks, clinical consortia, and other complex efforts that benefit from tight coordination among multiple institutions and a federal sponsor.

Funding under this announcement is substantial but intentionally concentrated. NIDDK anticipated making a single award (ExpectedAwards: 1), with an estimated total funding level of $17,100,000. The listing also notes an award ceiling of $700,000, which typically refers to an upper bound for a defined budget period or annual direct cost level depending on how the FOA is structured, while the overall total reflects the full projected commitment across the life of the award. There is no cost sharing or matching requirement, so applicants are not required to contribute non-federal funds as a condition of receiving the award.

Eligibility is limited to institutions of higher education, including private universities and public or state-controlled universities. The limited competition framing implies the applicant pool is constrained, often to existing network participants or a defined set of organizations capable of continuing an established study group infrastructure. The program is categorized under discretionary funding and falls within the broad activity area of health (with the opportunity also tagged under food and nutrition health), and it is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), which is the federal catalog listing that corresponds to NIDDK extramural research support.

Key administrative details include the Funding Opportunity Number RFA-DK-09-505, with the opportunity posted and created on January 7, 2010. The original and current application due date was March 15, 2010, and the opportunity was archived on April 15, 2010, indicating it is no longer open for new applications. The official full announcement was made available through an NIH grants web link, and the contact provided for access or linking problems was the NIH Office of Extramural Research (OER) webmaster email.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The funding opportunity is titled "Limited Competition for the Continuation of the Pediatric Acute Liver Failure Study Group (U01)."

Which federal agency and NIH institute issued this opportunity?

This is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What is the main purpose of this funding opportunity?

The central goal is to support a competing continuation of the Pediatric Acute Liver Failure Study Group. The intent is to continue and advance an established, organized research effort rather than start an entirely new, unrelated project.

What scientific or clinical area does the opportunity focus on?

The scientific focus is pediatric acute liver failure, described as a severe and often rapidly progressing condition in children. The opportunity emphasizes coordinated, multi-site clinical research and shared data resources to improve understanding, diagnosis, management, and outcomes.

What funding mechanism is used (and what does it mean for how the project is run)?

The award uses the NIH Cooperative Agreement mechanism (U01). A U01 is intended for projects where NIH expects substantial involvement, meaning NIH program staff have an active partnership role through oversight, coordination, and collaboration while the funded group conducts the work.

Why does the announcement describe this as a "limited competition"?

The limited competition framing indicates the applicant pool is constrained. Based on the description, this is often the case for opportunities intended to continue an existing network or study group infrastructure rather than establish a new effort.

How many awards did NIDDK expect to make?

NIDDK anticipated making a single award (ExpectedAwards: 1).

What is the estimated total funding level for this opportunity?

The estimated total funding level is $17,100,000, reflecting the full projected commitment across the life of the award.

What does the listed award ceiling of $700,000 mean?

The listing notes an award ceiling of $700,000. The description indicates this typically refers to an upper bound for a defined budget period or an annual direct cost level, depending on how the funding opportunity announcement is structured.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement, so applicants are not required to contribute non-federal funds as a condition of receiving the award.

Who is eligible to apply?

Eligibility is limited to institutions of higher education, including private universities and public or state-controlled universities.

What is the activity area or program category associated with this opportunity?

The program is categorized under discretionary funding and falls within the broad activity area of health. It is also tagged under food and nutrition health.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), corresponding to NIDDK extramural research support.

What is the Funding Opportunity Number?

The Funding Opportunity Number is RFA-DK-09-505.

When was the opportunity posted and created?

The opportunity was posted and created on January 7, 2010.

What was the application due date?

The original and current application due date was March 15, 2010.

Is this opportunity still open for applications?

No. The opportunity was archived on April 15, 2010, which indicates it is no longer open for new applications.

Where was the full official announcement made available?

The full announcement was made available through an NIH grants web link (as referenced in the opportunity information).

Who should be contacted for access or linking problems with the announcement?

The contact provided for access or linking problems was the NIH Office of Extramural Research (OER) webmaster email.

Browse more opportunities from the same agency: National Institutes of Health

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Next opportunity: Limited Competition for the Continuation of the Adult Acute Liver Failure Study Group (U01)

Previous opportunity: Sonoran Joint Venture FY2010 Awards Program

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