Opportunity Information: Apply for RFA AA 17 003
Apply for RFA AA 17 003
- The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project Sites (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242, 93.273, 93.279,.
- This funding opportunity was created on May 31, 2016 and posted on May 31, 2016.
- Applicants must submit their applications by Nov 09, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
This grant opportunity, RFA-AA-17-003, is a limited-competition Funding Opportunity Announcement from HHS/NIH (listed under HHS-NIH11) that supports the continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project Sites through a U01 cooperative agreement mechanism. The purpose is not to create new NCANDA sites or expand eligibility broadly, but to keep the existing consortium infrastructure and data-collection work operating into the next phase of the study. Even though the general grants.gov eligibility list includes a wide range of entity types (governments, tribal entities, nonprofits, universities, and some for-profit organizations), the FOA text makes clear that only the current NCANDA Research Project Site awardees are eligible to apply, meaning this is effectively a renewal/continuation competition restricted to the incumbent NCANDA site institutions.
The core focus of the funded work is the ongoing acquisition of research data using NCANDA's standardized, consortium-wide protocol. These Research Project Sites function as the front line of the project: they recruit and follow adolescent participants and collect harmonized measures that allow data to be pooled across the nation-wide network. The scientific aim driving the data collection is to understand how alcohol use and drinking patterns affect brain structure and brain function during adolescence and as individuals transition into early adulthood. Because adolescence is a period of rapid neurodevelopment, the consortium design is built around consistent, longitudinal measurement so that developmental trajectories and alcohol-related deviations can be detected with greater confidence than would be possible with isolated, single-site studies.
This FOA specifically supports the continuation of the Research Project Sites, while companion announcements are referenced for other core consortium components. RFA-AA-17-004 is intended to continue the NCANDA Administrative Resource, which typically coordinates consortium operations such as governance, scheduling, communications, and protocol compliance. RFA-AA-17-005 is intended to continue the NCANDA Data Analysis Resource, which generally supports centralized data management, harmonization, and analytic leadership across sites. Together, these coordinated awards maintain the overall NCANDA ecosystem, with the Research Project Sites generating standardized participant-level data and the administrative and analytic cores ensuring that the multi-site study runs as a cohesive national program.
From an administrative standpoint, the opportunity is categorized as discretionary funding and uses the cooperative agreement model (U01). That mechanism usually indicates that NIH will have substantial programmatic involvement beyond what is typical for a standard research grant, often including participation in steering committees, protocol oversight, milestone expectations, and coordination requirements that ensure each site contributes comparable data that can be combined across the consortium. The FOA lists CFDA numbers 93.242, 93.273, and 93.279, reflecting the federal assistance catalog classifications associated with NIH alcohol and related biomedical research programs.
Key dates and basic award information are also provided. The opportunity was created and posted on May 31, 2016, with an application due date (original and current closing date) of November 9, 2016. The listing indicates an expected number of awards of 1, which commonly reflects how the posting is represented in the system rather than necessarily implying that only one research site in the consortium would be supported, but the text itself emphasizes continuation of the Research Project Sites as a group function within NCANDA. No award ceiling amount is specified in the provided extract.
In practical terms, the announcement is best understood as a continuation mechanism to keep NCANDA's existing site-based data collection moving forward under the same shared protocol, preserving the value of the longitudinal cohort and ensuring continuity in measurements needed to evaluate alcohol-related influences on neurodevelopment from adolescence into early adulthood.
Frequently Asked Questions (FAQ) - RFA-AA-17-003 (NCANDA Research Project Sites Continuation)
What is the funding opportunity number and title?
The opportunity is RFA-AA-17-003. It is a limited-competition Funding Opportunity Announcement (FOA) from HHS/NIH that supports the continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project Sites.
Which federal agency is offering this opportunity?
This FOA is offered by HHS/NIH (listed under HHS-NIH11).
What type of grant mechanism is being used?
The award uses a U01 cooperative agreement mechanism. A cooperative agreement typically means NIH will have substantial programmatic involvement in the work, beyond what is typical for a standard research grant.
Is this a competitive opportunity open to new applicants?
No. This is a limited-competition FOA. While general Grants.gov eligibility categories can look broad, the FOA text specifies that only the current NCANDA Research Project Site awardees are eligible to apply. In practice, it functions as a restricted continuation/renewal competition for incumbent NCANDA site institutions.
Are new NCANDA Research Project Sites being created through this announcement?
No. The purpose is not to create new NCANDA sites or broadly expand eligibility. The intent is to keep the existing consortium infrastructure and data-collection work operating into the next phase of the study.
What is the main purpose of funding under RFA-AA-17-003?
The main purpose is to support ongoing acquisition of research data using NCANDA's standardized, consortium-wide protocol. The funded Research Project Sites are responsible for participant-facing, site-based data collection that can be pooled across the national network.
What do NCANDA Research Project Sites do under this FOA?
NCANDA Research Project Sites serve as the front line of the project by recruiting and following adolescent participants and collecting harmonized measures under the consortium's standardized protocol so that data are comparable across sites and can be combined for analysis.
What scientific questions is NCANDA designed to address?
The consortium's data collection is driven by the aim of understanding how alcohol use and drinking patterns affect brain structure and brain function during adolescence and as individuals transition into early adulthood. The design emphasizes consistent, longitudinal measurement during a period of rapid neurodevelopment.
Why is longitudinal, standardized data collection emphasized?
The consortium approach is built around consistent, longitudinal measurement so that developmental trajectories and alcohol-related deviations can be detected with greater confidence than would be possible with isolated, single-site studies.
Does this FOA fund NCANDA administration or centralized data analysis?
This FOA specifically supports continuation of the Research Project Sites. It references companion announcements for other consortium components: RFA-AA-17-004 (to continue the NCANDA Administrative Resource) and RFA-AA-17-005 (to continue the NCANDA Data Analysis Resource).
What are the companion FOAs and what do they cover?
The companion announcements referenced are: RFA-AA-17-004, intended to continue the NCANDA Administrative Resource (coordination of consortium operations such as governance, scheduling, communications, and protocol compliance), and RFA-AA-17-005, intended to continue the NCANDA Data Analysis Resource (centralized data management, harmonization, and analytic leadership across sites).
How do the Research Project Sites fit into the overall NCANDA consortium structure?
The coordinated awards work together to maintain the NCANDA ecosystem: Research Project Sites generate standardized participant-level data, while the administrative and analytic resources help ensure the multi-site study operates as a cohesive national program.
What does "discretionary funding" mean in this listing?
The opportunity is categorized as discretionary funding in the listing information provided.
What does the cooperative agreement model (U01) imply for how the project is run?
Based on the description provided, the U01 mechanism generally indicates substantial NIH programmatic involvement. This often includes participation in steering committees, protocol oversight, milestone expectations, and coordination requirements to ensure each site contributes comparable data that can be combined across the consortium.
What CFDA numbers are associated with this opportunity?
The FOA lists CFDA numbers 93.242, 93.273, and 93.279.
When was this opportunity posted and when was it due?
The opportunity was created and posted on May 31, 2016. The application due date (original and current closing date) is November 9, 2016.
How many awards are expected?
The listing indicates an expected number of awards of 1. The description notes that this may reflect how the posting is represented in the system rather than necessarily meaning only one NCANDA research site would be supported, since the FOA emphasizes continuation of the Research Project Sites as a group function within the consortium.
Is there an award ceiling amount stated in the provided information?
No award ceiling amount is specified in the provided extract.
What is the practical intent of this FOA?
In practical terms, it is a continuation mechanism to keep NCANDA's existing site-based data collection moving forward under the same shared protocol, preserving the value of the longitudinal cohort and ensuring continuity in the measurements needed to evaluate alcohol-related influences on neurodevelopment from adolescence into early adulthood.
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| Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24) Apply for RFA AA 17 005 Funding Number: RFA AA 17 005 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $600,000 |
| Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24) Apply for RFA AA 17 004 Funding Number: RFA AA 17 004 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $350,000 |
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| U.S.-Russia Bilateral Collaborative Research Partnerships on Cancer (R21) Apply for RFA CA 16 015 Funding Number: RFA CA 16 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
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| FY 2017 American Schools and Hospitals Abroad (ASHA) Program (Request for Comments) Apply for APS ASHA 17 000001 Funding Number: APS ASHA 17 000001 Agency: Agency for International Development Category: Education, Health Funding Amount: $2,000,000 |
| Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33) Apply for RFA CA 17 013 Funding Number: RFA CA 17 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Innovative Technologies for Cancer-Relevant Biospecimen Science (R21) Apply for RFA CA 17 012 Funding Number: RFA CA 17 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33) Apply for RFA CA 17 011 Funding Number: RFA CA 17 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| PDX Data Commons and Coordinating Center (PDCCC) for the PDX Development and Trial Centers Research Network (PDXNet) (U24) Apply for RFA CA 17 004 Funding Number: RFA CA 17 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $650,000 |
| PDX Development and Trial Centers (PDTCs) (U54) Apply for RFA CA 17 003 Funding Number: RFA CA 17 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $800,000 |
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