Limited Competition Specific pathogen free macaque colonies (U42) | Apply Online

Opportunity Summary:

The Limited Competition Specific Pathogen Free (SPF) Macaque Colonies (U42) funding opportunity (PAR-11-116) is a National Institutes of Health (NIH) cooperative agreement designed to continue supporting established SPF macaque breeding and holding colonies that were previously funded under an earlier NIH initiative (RFA RR-00-004). The central goal is to preserve and sustain a specialized nonhuman primate resource that directly supports AIDS and HIV-related research by ensuring access to macaques that are free of particular infectious agents. These animals are valuable because certain macaque viruses can interfere with immunology and virology study outcomes, complicate interpretation of experimental results, and in some cases increase occupational health risks for staff who handle the animals.

A key feature of the opportunity is that it is focused on continuity rather than launching brand-new colonies from scratch. Applicants are expected to demonstrate that they can keep existing SPF colonies operating at least at their current size and capability, which implies maintaining stable breeding, veterinary care, husbandry standards, and biosecurity practices that preserve SPF status over time. Because this is a cooperative agreement (U42), the NIH typically has a more involved role than in a standard grant, meaning awardees should be prepared for active coordination, reporting, and programmatic collaboration consistent with cooperative agreement mechanisms.

The announcement lays out several required operational elements that applicants must address in their proposals. First, they must provide a clear plan for maintaining SPF colonies at minimally current levels, which generally means sustaining infrastructure and procedures that prevent introduction and spread of excluded pathogens. Second, applicants must describe how they will distribute animals to AIDS researchers, and distribution must prioritize NIH-funded investigators first. This emphasis reflects the program’s role as a national research infrastructure resource rather than a colony intended primarily for local or internal institutional use. Third, applicants must outline how they will assay (test) animals for the presence of specific viruses, which is essential both to confirm SPF status and to provide researchers with confidence in the health background of animals used in sensitive infectious disease and immunology studies. Fourth, applicants must include plans for typing animals at specific major histocompatibility complex (MHC) loci. MHC typing is important because macaque immune genetics can strongly influence responses in vaccine studies, pathogenesis experiments, and immunological assays, and having typed animals improves study design and interpretability. Fifth, applicants must explain how they will finance colony operations, indicating that reviewers will look closely at financial sustainability, cost structure, and practical plans for covering ongoing operating expenses.

From an eligibility standpoint, the opportunity is broadly open to a range of organizational types, including public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits). The eligibility language also explicitly notes inclusion of several categories of institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions, among others referenced in the “Additional Information on Eligibility” section of the full announcement. There is no cost sharing or matching requirement listed, which means applicants are not required to provide a formal non-federal match as a condition of award, though they still need to present a credible operational financing plan.

Administratively, this opportunity falls under NIH’s research infrastructure-related programming (CFDA 93.351 and 93.389 as listed in the source data). The posting date is noted as February 14, 2011, with related dates indicating the announcement lifecycle and an archive date of February 10, 2014. For full details, NIH directs applicants to the complete funding announcement at the NIH grants guide link (PAR-11-116). For access or technical issues with the online announcement, the listed point of contact is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), which is meant for troubleshooting access and linking problems rather than scientific program questions.

In practical terms, the program is best understood as NIH maintaining a dependable pipeline of rigorously screened, genetically characterized macaques for HIV/AIDS research, with expectations that awardees will operate as resource centers. Successful applications would therefore be expected to show strong colony management capacity, robust pathogen surveillance and documentation, well-defined distribution policies that align with NIH priority rules, proven laboratory capability (or well-supported arrangements) for viral assays and MHC typing, and a realistic plan for long-term financial and operational stability.

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Education Health

Next opportunity: Limited Competition Specific pathogen free macaque colonies (U24)

Previous opportunity: Evaluation of the Impact of Work or School Exclusion Criteria on the Spread of Influenza and Influenza like Illness (U01)

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for PAR 11 116

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (PAR 11 116) also looked into and applied for these:

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "PAR 11 116", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.