Evaluation of the Impact of Work or School Exclusion Criteria on the Spread of Influenza and Influenza like Illness (U01) | Apply Online

Opportunity Summary:

The Centers for Disease Control and Prevention (CDC) released a discretionary funding opportunity, RFA-CK-11-007, titled "Evaluation of the Impact of Work or School Exclusion Criteria on the Spread of Influenza and Influenza-like Illness (U01)." The grant is structured as a cooperative agreement, meaning CDC would be actively involved with awardees during the project rather than simply providing funds with minimal federal engagement. The overall intent is to support applied research that tests how well different "stay home" or exclusion rules work in real-world settings to reduce the spread of influenza-like illness (ILI) and laboratory-confirmed influenza. The focus is practical: when people develop symptoms, which exclusion criteria meaning how soon they should leave, how long they should remain out, and what conditions should be met before returning actually leads to fewer infections among coworkers, patients, students, or classmates.

The core research goal is to determine the effectiveness of alternative illness exclusion criteria across multiple environments. CDC is specifically interested in evidence from healthcare workplaces, non-healthcare workplaces, and school settings. These contexts matter because transmission dynamics, exposure intensity, contact patterns, and consequences of illness differ substantially between, for example, a hospital unit, an office environment, and a classroom. The studies supported under this announcement are expected to directly assess whether particular exclusion policies prevent additional cases of ILI and confirmed influenza, rather than relying only on theory or modeling. In other words, the opportunity aims to generate decision-ready evidence that can inform public health guidance and employer or school policies during seasonal influenza periods and potentially during more severe outbreaks.

Funding details indicate CDC anticipated making two awards under this announcement, with an award ceiling of $1,000,000 and no stated minimum award amount (award floor of $0). The CFDA listing is 93.283 (Centers for Disease Control and Prevention Investigations and Technical Assistance). There is no cost-sharing or matching requirement, which generally lowers the barrier for applicants because they are not required to contribute non-federal funds to the project budget. Eligibility is listed as unrestricted, meaning the competition was open to any entity type, subject to any additional clarifications that may have been included in the full announcement. The opportunity was posted and created on February 14, 2011, with an original and current closing date of March 29, 2011, and an archive date of April 28, 2011, indicating it is a past (archived) funding announcement rather than an active competition.

In practical terms, an applicant responding to this opportunity would be proposing a study design capable of comparing exclusion criteria in a way that yields credible conclusions. That could involve comparing shorter versus longer exclusion periods, symptom-based versus fever-based rules, return-to-work or return-to-school requirements, or different screening and notification approaches tied to exclusion decisions. Because CDC emphasized both ILI outcomes and laboratory-confirmed influenza outcomes, a strong project concept would typically incorporate methods to capture syndromic illness data while also collecting specimens or otherwise confirming influenza infections through lab testing, enabling the study to distinguish influenza from other respiratory viruses that can look similar clinically.

Administrative details in the synopsis note that the full announcement link was not active in the summary view and that applicants needing help accessing the complete materials were directed to contact CDCs Procurement and Grants Office (PGO), Technical Information and Management Section (TIMS), by phone at 770-488-2700. This contact point would have supported prospective applicants with technical access issues or questions about the application package and requirements contained in the full announcement.

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