Opportunity Information: Apply for RFA HL 12 010
Apply for RFA HL 12 010
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Lung Repair and Regeneration Consortium Administrative Coordinating Center (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.838 Lung Diseases Research.
- This funding opportunity was created on Oct 27, 2010 and posted on Oct 27, 2010.
- Applicants must submit their applications by Feb 10, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,300,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities State governments Independent school districts City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Lung Repair and Regeneration Consortium Administrative Coordinating Center (ACC) (U01) funding opportunity (RFA-HL-12-010) is a National Institutes of Health program administered through the National Heart, Lung, and Blood Institute (NHLBI) to establish a single, central coordinating hub for the Lung Repair and Regeneration Consortium (LRRC). The broader purpose of the LRRC is to bring together highly integrated, multidisciplinary research teams to close key knowledge gaps in the basic mechanisms that control lung repair and regeneration, and to use that knowledge to move toward regenerative medicine strategies that could ultimately help reverse serious, life-limiting pulmonary diseases. Rather than funding another standalone lab project, this specific award supports the administrative and coordinating infrastructure that allows multiple independent, team-based research projects within the consortium to work as a coherent, collaborative program.
At a practical level, the ACC is meant to be the operational backbone of the LRRC. The consortium model предполага that several separate research groups (each led by multi-investigator teams) will be developing and applying new enabling capabilities for the field, such as biological reagents, experimental models, imaging approaches, and data-analysis tools. These kinds of shared tools are highlighted because they can accelerate progress across the entire consortium and, ideally, beyond it by making it easier for researchers to test hypotheses about lung regeneration and to translate findings into early regenerative strategies. The consortium is also expected to include a skills development core for trainees, signaling an emphasis not only on producing results and resources, but also on building a workforce capable of working across disciplines in lung biology, repair mechanisms, engineering, imaging, and quantitative analysis.
This opportunity uses the Cooperative Agreement mechanism (U01), which typically means NHLBI expects to have substantial involvement in how the program is carried out compared to a standard investigator-initiated grant. In other words, the ACC is not just doing routine grants management; it is participating in an actively managed, multi-site effort where coordination, standardization, communication, and shared decision-making are central to success. While the excerpt does not list the ACC task set in detail, the intent is clear: the awardee would support consortium-wide organization, help integrate activities across independent projects, and enable the collaborative environment needed for complex, multidisciplinary work aimed at lung repair and regeneration.
Funding for the ACC is planned as a single award, with an estimated total funding level of $6,300,000. The expected number of awards is 1, reflecting the idea that one ACC should serve the entire consortium. The funding opportunity is categorized under Health and references CFDA numbers 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.838 (Lung Diseases Research). There is no cost sharing or matching requirement indicated.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants listed include public and private institutions of higher education, for-profit organizations (including small businesses), nonprofit organizations (both 501(c)(3) and certain non-501(c)(3) entities), and various government entities (state, county, city/township, special district), as well as public housing authorities and tribal governments or tribal organizations. The announcement explicitly notes additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, regional organizations, U.S. territories or possessions, eligible federal agencies, and foreign (non-U.S.) entities.
Key dates in the record show the opportunity was posted on October 27, 2010, with an original and current closing date of February 10, 2011, and an archive date of March 13, 2011. The full announcement and further details were provided through NIH’s grants guide (with an additional information link to the RFA), and NIH Office of Extramural Research web support contacts were included for access or technical linking issues.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the Lung Repair and Regeneration Consortium Administrative Coordinating Center (ACC) (U01) funding opportunity, RFA-HL-12-010. It is a National Institutes of Health (NIH) program administered through the National Heart, Lung, and Blood Institute (NHLBI).
What is being funded: a research project or a coordinating center?
The award supports an Administrative Coordinating Center (ACC), not another standalone laboratory research project. The ACC is intended to provide the administrative and coordinating infrastructure that enables multiple independent, team-based research projects within the consortium to function as a single, collaborative program.
What is the Lung Repair and Regeneration Consortium (LRRC) and what is its purpose?
The LRRC is a consortium designed to bring together highly integrated, multidisciplinary research teams to close key knowledge gaps in the basic mechanisms that control lung repair and regeneration. The broader goal is to use that knowledge to move toward regenerative medicine strategies that could ultimately help reverse serious, life-limiting pulmonary diseases.
What is the role of the ACC within the LRRC?
The ACC is meant to be the operational backbone and central coordinating hub for the entire consortium. Its purpose is to support consortium-wide organization, help integrate activities across independent projects, and enable the coordinated, collaborative environment needed for complex, multidisciplinary efforts focused on lung repair and regeneration.
Why is a central coordinating hub needed?
The consortium model assumes several separate research groups will be working in parallel on enabling capabilities and shared resources. A single ACC helps those independent efforts operate as a coherent program through coordination, communication, standardization, and shared decision-making across multiple sites and teams.
What kinds of work are consortium research teams expected to do (that the ACC would help coordinate)?
The consortium is expected to develop and apply enabling capabilities that can accelerate progress across the LRRC. Examples mentioned include biological reagents, experimental models, imaging approaches, and data-analysis tools. These shared tools are highlighted because they can support hypothesis testing and help translate findings toward early regenerative strategies.
Does the consortium include training or workforce development?
Yes. The consortium is expected to include a skills development core for trainees. This indicates an emphasis on building a workforce that can work across disciplines relevant to lung biology and regeneration, including areas such as repair mechanisms, engineering, imaging, and quantitative analysis.
What grant mechanism is used for this opportunity?
This opportunity uses the Cooperative Agreement mechanism (U01).
What does the U01 Cooperative Agreement mechanism imply?
A U01 cooperative agreement typically means NHLBI expects substantial involvement in how the program is carried out, compared to a standard investigator-initiated grant. The ACC would participate in an actively managed, multi-site effort where coordination, communication, standardization, and shared decision-making are central to success.
How many awards are expected to be made?
The expected number of awards is 1, reflecting that a single ACC is intended to serve the entire consortium.
What is the planned funding level for the ACC award?
The planned funding is a single award with an estimated total funding level of $6,300,000.
Is cost sharing or matching required?
No cost sharing or matching requirement is indicated in the provided information.
What is the CFDA listing information for this opportunity?
The opportunity references CFDA numbers 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.838 (Lung Diseases Research).
How is this opportunity categorized?
The opportunity is categorized under Health.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants listed include public and private institutions of higher education, for-profit organizations (including small businesses), nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), and a range of government entities.
Are state or local government entities eligible?
Yes. Eligible government entities listed include state, county, city/township, and special district governments, as well as public housing authorities.
Are tribal governments or tribal organizations eligible?
Yes. Tribal governments and tribal organizations are included among eligible applicants.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly listed among eligible applicant groups.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The announcement explicitly notes eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are explicitly listed as eligible applicants.
Are regional organizations eligible?
Yes. Regional organizations are included in the explicitly listed eligible groups.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are listed among eligible applicants.
Are foreign (non-U.S.) entities eligible?
Yes. Foreign (non-U.S.) entities are explicitly included as eligible applicants.
When was the opportunity posted?
The record shows the opportunity was posted on October 27, 2010.
What was the application closing date?
The original and current closing date listed is February 10, 2011.
Is this opportunity still open?
Based on the provided dates, the opportunity is not open: it had a closing date of February 10, 2011, and an archive date of March 13, 2011.
Where were full details and the official announcement provided?
Full details were provided through NIH's grants guide, with an additional information link to the RFA (RFA-HL-12-010).
Who provides support if there are access or technical linking issues?
NIH Office of Extramural Research web support contacts were included for access or technical linking issues.
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