Opportunity Information: Apply for PA 13 117
Apply for PA 13 117
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Mechanisms, Models, Measurement, Management in Pain Research (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Feb 22, 2013 and posted on Feb 15, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public housing authorities/Indian housing authorities Private institutions of higher education State governments Independent school districts Small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Mechanisms, Models, Measurement, Management in Pain Research (R03) is an NIH discretionary grant opportunity (Funding Opportunity Number PA-13-117) designed to spark a broad mix of basic, clinical, and translational pain research aligned with the missions of multiple NIH Institutes and Centers. The announcement reflects NIH's view that pain remains a major unsolved health challenge despite progress in specific areas like mapping neural pathways. A central theme is that pain is highly individual in how it is experienced, how it becomes persistent, and how it responds to treatment, which creates an urgent need for better scientific explanations and more effective approaches to assessment and care.
The scientific scope is intentionally wide, spanning work at very small biological scales (molecular and cellular mechanisms, neurobiological pathways) through whole-person and population perspectives (behavioral science, psychosocial drivers, and social determinants). The FOA highlights a key knowledge gap: limited understanding of how and why some people move from acute pain after an injury to chronic pain states. Projects that clarify mechanisms of chronification, improve experimental or clinical models of pain, strengthen how pain is measured, or develop and test strategies for pain management all fit within the intent of the program, so long as they connect to the missions of the participating NIH components.
Because pain is influenced by biology, psychology, clinical context, and environment, the FOA strongly encourages interdisciplinary and multidisciplinary teams. It also explicitly signals interest in broadening participation in the research community by encouraging applications from investigators who are underrepresented, including minority, disabled, and women scientists. The opportunity is categorized under health, education, and social services-related federal funding activity areas, and it is associated with multiple CFDA programs across NIH that touch pain-relevant domains such as drug abuse and addiction research (93.279), nursing research (93.361), cancer prevention and causes (93.393), neuroscience and neurological disorders extramural research (93.853), child health and human development (93.865), and aging research (93.866). This spread underscores that NIH is looking for pain research that is relevant across diseases, life stages, and care settings.
Eligibility is broad and includes many types of U.S. organizations and governments as well as foreign entities. Eligible applicants listed in the notice include for-profit organizations (including small businesses), nonprofits (with and without 501(c)(3) status), public and private institutions of higher education, state and local government entities (state, county, city/township, special district), independent school districts, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations (both federally recognized and other than federally recognized, as specified). The eligibility section also calls out a range of institution types and organizational categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander serving institutions, along with faith-based and community-based organizations, regional organizations, and eligible federal agencies. Non-U.S. (foreign) organizations and institutions are eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined in NIH policy. The announcement states there is no cost sharing or matching requirement.
Administratively, the FOA was posted February 15, 2013, created February 22, 2013, and had an original and current closing date of May 7, 2016, with an archive date of June 7, 2016, meaning it is no longer active as an open competition but remains an important reference for NIH pain research priorities during that period. The sponsor agency is the National Institutes of Health, and the full archived announcement was hosted through the NIH Grants Guide (link provided in the source). For access or technical issues with the electronic announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled Mechanisms, Models, Measurement, Management in Pain Research (R03).
Who is the sponsoring agency?
The sponsor is the National Institutes of Health (NIH).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-13-117.
What kind of grant mechanism is this?
It is an NIH discretionary grant opportunity using the R03 mechanism, as stated in the opportunity title.
What is the overall purpose of this funding opportunity?
The FOA is designed to spark a broad mix of basic, clinical, and translational pain research aligned with the missions of multiple NIH Institutes and Centers. It reflects NIH's view that pain remains a major unsolved health challenge and emphasizes the need for better scientific explanations and more effective approaches to assessment and care.
What central theme about pain does the FOA emphasize?
A central theme is that pain is highly individual in how it is experienced, how it becomes persistent, and how it responds to treatment. This individual variability is presented as a key reason the field needs improved explanations, assessment tools, and management approaches.
What scientific areas are within scope?
The scope is intentionally broad, spanning:
- Small biological scales, including molecular and cellular mechanisms and neurobiological pathways
- Whole-person and population perspectives, including behavioral science, psychosocial drivers, and social determinants
What major knowledge gap does the FOA highlight?
The FOA highlights a key gap: limited understanding of how and why some people transition from acute pain after an injury to chronic pain states (often described as mechanisms of chronification).
What types of projects fit the intent of the program?
Projects consistent with the FOA include those that:
- Clarify mechanisms of chronification (acute-to-chronic pain transition)
- Improve experimental or clinical models of pain
- Strengthen how pain is measured
- Develop and test strategies for pain management
Projects should connect to the missions of the participating NIH components.
Is the FOA limited to a specific disease area or patient population?
No. The opportunity signals interest in pain research relevant across diseases, life stages, and care settings, reflecting participation across multiple NIH components and related CFDA programs.
Does the FOA encourage interdisciplinary or multidisciplinary teams?
Yes. Because pain is influenced by biology, psychology, clinical context, and environment, the FOA strongly encourages interdisciplinary and multidisciplinary research teams.
Does the FOA encourage applications from underrepresented investigators?
Yes. The FOA explicitly signals interest in broadening participation by encouraging applications from investigators who are underrepresented, including minority, disabled, and women scientists.
What federal funding activity areas is this opportunity associated with?
The opportunity is categorized under federal funding activity areas related to health, education, and social services.
Which CFDA programs are associated with this FOA?
The FOA is associated with multiple NIH CFDA programs that touch pain-relevant domains, including:
- 93.279 Drug Abuse and Addiction Research Programs
- 93.361 Nursing Research
- 93.393 Cancer Cause and Prevention Research
- 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders
- 93.865 Child Health and Human Development
- 93.866 Aging Research
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. organizations and governments as well as foreign entities. Eligible applicants listed include:
- For-profit organizations (including small businesses)
- Nonprofit organizations (with or without 501(c)(3) status)
- Public and private institutions of higher education
- State and local governments (state, county, city/township, special district)
- Independent school districts
- Public housing authorities / Indian housing authorities
- Tribal governments (federally recognized and other than federally recognized, as specified)
- Tribal organizations (as specified)
- Faith-based and community-based organizations
- Regional organizations
- Eligible federal agencies
Are specific institution types called out as eligible?
Yes. The eligibility section calls out multiple institution types and organizational categories, including:
- HBCUs (Historically Black Colleges and Universities)
- Hispanic-serving institutions
- Tribally controlled colleges and universities
- Alaska Native and Native Hawaiian serving institutions
- Asian American Native American Pacific Islander serving institutions
Can non-U.S. (foreign) organizations apply?
Yes. The announcement states that non-U.S. (foreign) organizations and institutions are eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
Yes. The announcement states that non-U.S. components of U.S. organizations are eligible.
Are foreign components allowed?
Yes. Foreign components are allowed as defined in NIH policy.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
When was this FOA posted and created?
It was posted February 15, 2013 and created February 22, 2013.
What were the closing date and archive date?
The original and current closing date was May 7, 2016, and the archive date was June 7, 2016.
Is this funding opportunity still open?
No. Based on the closing and archive dates provided, it is no longer active as an open competition, though it remains a reference for NIH pain research priorities during that period.
Where was the full announcement hosted?
The full archived announcement was hosted through the NIH Grants Guide (link referenced in the source information).
Who should be contacted for access or technical issues with the electronic announcement?
For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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