Opportunity Information: Apply for PA 09 098
Apply for PA 09 098
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Mechanisms of Alcohol and Nicotine Co Dependence (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Feb 13, 2009 and posted on Feb 13, 2009.
- Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) County governments Small businesses State governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities Private institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity titled "Mechanisms of Alcohol and Nicotine Co-Dependence (R21)" (Funding Opportunity Number PA-09-098) is a discretionary NIH funding announcement sponsored jointly by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). Its central goal is to support exploratory, early-stage research that clarifies why alcohol and nicotine are so often used together and why dependence on one frequently co-occurs with dependence on the other. The scientific emphasis is on identifying neurobiological and behavioral mechanisms that drive concurrent use, escalation, and maintenance of co-dependence, including processes that may explain shared vulnerability, cross-reinforcement, or mutually reinforcing patterns of addiction.
This announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which is typically intended for projects that are innovative, hypothesis-generating, or at a proof-of-concept stage rather than fully mature programs of research. In practical terms, the R21 format is meant to let investigators test new ideas, develop new models or methods, or gather preliminary data that can later support a larger, more definitive study. The FOA also notes that it runs in parallel with another announcement of identical scientific scope, PA-09-099, which uses the R01 mechanism. That parallel structure signals that NIH is interested in both early exploratory work (R21) and more extensive, fully powered research programs (R01) on the same overarching topic, allowing applicants to choose the mechanism that best fits the maturity and scale of their proposed work.
Funding under this FOA is subject to the availability of federal funds and depends on NIH receiving a sufficient number of applications that score well in peer review. The listed award ceiling is $200,000, reflecting the limited, exploratory nature of the R21 mechanism as presented in the opportunity summary. The announcement does not promise a specific number of awards; instead, it indicates that awards will be made only if meritorious applications are submitted and budgets allow.
Eligibility is intentionally broad and includes a wide range of public, private, nonprofit, and for-profit entities. Eligible applicants include institutions of higher education (both public and private), nonprofit organizations (including those with and without 501(c)(3) status), small businesses and other for-profit organizations, and multiple levels of government such as state, county, city/township, special district governments, and independent school districts. It also explicitly includes Native American tribal governments (federally recognized) and other tribal organizations, as well as public housing authorities/Indian housing authorities. The eligibility description further expands to include a variety of specialized and mission-focused institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. Notably, non-U.S. entities (foreign organizations) are also listed as eligible, which indicates NIH’s willingness to consider relevant research capacity and expertise outside the United States where appropriate. The opportunity states that there is no cost-sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of receiving an award.
From an administrative standpoint, the opportunity was posted and created on February 13, 2009, with an original and final closing date of May 7, 2012, and an archive date of June 7, 2012. It is associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs), which reflect the joint NIAAA-NIDA interest in co-use and co-dependence. The official full announcement was hosted on the NIH grants site at the time, and the provided support contacts are the NIH Office of Extramural Research (OER) web staff for access or linking issues, rather than a scientific/research contact listed in the excerpt.
In plain terms, this FOA was designed to stimulate new, creative research aimed at explaining the shared and interacting mechanisms behind alcohol and nicotine co-dependence, using the R21 pathway to accelerate early discovery and method development. Applicants with ideas that could open up new lines of evidence about co-use, co-addiction risk, or the brain and behavioral pathways that tie these substances together were the intended audience, especially where the work could later grow into larger-scale projects under mechanisms like the R01.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "Mechanisms of Alcohol and Nicotine Co-Dependence (R21)" and the Funding Opportunity Number is PA-09-098.
Which agencies sponsor this funding opportunity?
This is a discretionary NIH funding announcement sponsored jointly by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA).
What is the main purpose of this FOA?
The central goal is to support exploratory, early-stage research that helps clarify why alcohol and nicotine are so often used together and why dependence on one frequently co-occurs with dependence on the other.
What scientific areas does the FOA emphasize?
The emphasis is on identifying neurobiological and behavioral mechanisms that drive concurrent use, escalation, and maintenance of alcohol-nicotine co-dependence, including mechanisms that may explain shared vulnerability, cross-reinforcement, or mutually reinforcing patterns of addiction.
What grant mechanism is used for PA-09-098?
This announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21).
What kind of projects are a good fit for an R21 under this announcement?
The R21 format is intended for projects that are innovative, hypothesis-generating, or at a proof-of-concept stage. It is designed to let investigators test new ideas, develop new models or methods, or gather preliminary data that could support a later, larger study.
Is there a related NIH opportunity for larger, more mature projects on the same topic?
Yes. This FOA runs in parallel with PA-09-099, which has identical scientific scope but uses the R01 mechanism. This allows applicants to choose the mechanism that best fits the maturity and scale of their proposed work.
What is the maximum award amount mentioned for this opportunity?
The listed award ceiling is $200,000, reflecting the limited, exploratory nature of the R21 mechanism as presented in the summary.
Does the FOA guarantee funding or a specific number of awards?
No. Funding is subject to the availability of federal funds and depends on NIH receiving a sufficient number of meritorious applications that score well in peer review. The announcement does not promise a specific number of awards.
Is cost sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement, so applicants are not required to contribute non-federal funds as a condition of receiving an award.
Who is eligible to apply?
Eligibility is broad and includes many types of public, private, nonprofit, and for-profit entities, including institutions of higher education (public and private), nonprofit organizations (with or without 501(c)(3) status), small businesses and other for-profit organizations, and multiple levels of government.
What types of government entities are specifically listed as eligible?
The eligibility list includes state, county, city/township, special district governments, and independent school districts.
Are tribal governments or tribal organizations eligible?
Yes. Native American tribal governments (federally recognized) and other tribal organizations are explicitly included as eligible applicants.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Are certain mission-focused or designated institutions explicitly included?
Yes. The eligibility description explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are included in the eligibility description.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are included in the eligibility description.
Are foreign (non-U.S.) organizations eligible?
Yes. Non-U.S. entities (foreign organizations) are listed as eligible, indicating NIH is willing to consider relevant research capacity and expertise outside the United States where appropriate.
When was this funding opportunity posted and when did it close?
The opportunity was posted and created on February 13, 2009. The original and final closing date was May 7, 2012. The archive date was June 7, 2012.
Which CFDA numbers are associated with this opportunity?
This FOA is associated with CFDA 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).
What does it mean that this is a discretionary NIH funding announcement?
In this context, "discretionary" indicates that awards depend on federal fund availability and on submitting applications that are strong enough to score well in peer review. It is not an entitlement and does not guarantee an award.
Who is listed as the contact in the information provided?
The excerpt references the NIH Office of Extramural Research (OER) web staff as support contacts for access or linking issues, rather than listing a scientific or research program contact in the provided text.
What kinds of research questions is this FOA trying to stimulate?
Based on the description, the FOA aims to stimulate new, creative research explaining shared and interacting mechanisms behind alcohol and nicotine co-dependence, particularly work that could open new lines of evidence about co-use, co-addiction risk, and the brain and behavioral pathways linking these substances.
How should an applicant decide between the R21 and the parallel R01 announcement?
The description suggests choosing the R21 (PA-09-098) for early-stage, exploratory, method-development, or proof-of-concept projects, and considering the parallel R01 (PA-09-099) for more extensive and fully powered research programs with the same scientific scope.
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| Funding Opportunity |
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| Mechanisms of Alcohol and Nicotine Co Dependence (R01) Apply for PA 09 099 Funding Number: PA 09 099 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Manufacturing Processes of Medical, Dental, and Biological Technologies (SBIR R43/R44) Apply for PA 09 113 Funding Number: PA 09 113 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Manufacturing Processes of Medical, Dental, and Biological Technologies (STTR R41/R42) Apply for PA 09 114 Funding Number: PA 09 114 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for the Treatment of Pregnant/Postpartum Women with Substance Related Disorders and/or In Utero Substance Exposed Neonates (R01) Apply for PA 09 106 Funding Number: PA 09 106 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for the Treatment of Pregnant/Postpartum Women with Substance Related Disorders and/or In Utero Substance Exposed Neonates (R21) Apply for PA 09 107 Funding Number: PA 09 107 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| The Integrative Cancer Biology Program (ICBP) Centers for Cancer Systems Biology (CCSB) (U54) Apply for RFA CA 09 011 Funding Number: RFA CA 09 011 Agency: National Institutes of Health Category: Education Health Funding Amount: $2,000,000 |
| Clinical Research Curriculum Award (K30) Apply for RFA RR 09 006 Funding Number: RFA RR 09 006 Agency: National Institutes of Health Category: Education Health Funding Amount: $275,000 |
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| Incorporating Cost Effectiveness Analysis Into Factors Affecting Quality of Life Health Related Research (R01) Apply for RFA NR 09 005 Funding Number: RFA NR 09 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
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| Building System Capacity for Implementing Evidence Based Practices in Substance Abuse Treatment and Prevention (R34) Apply for PA 09 105 Funding Number: PA 09 105 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Cancer Surveillance Using Health Claims based Data System (R03) Apply for PA 09 143 Funding Number: PA 09 143 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Cancer Surveillance Using Health Claims based Data System (R21) Apply for PA 09 144 Funding Number: PA 09 144 Agency: National Institutes of Health Category: Education Health Funding Amount: $275,000 |
| Cancer Surveillance Using Health Claims based Data System (R01) Apply for PA 09 145 Funding Number: PA 09 145 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Pilot and Feasibility Studies in Preparation for Drug Abuse Prevention Trials (R34) Apply for PA 09 146 Funding Number: PA 09 146 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Economic Studies of Health Insurance Coverage on Drug Abuse Treatment Availability, Access, Costs, and Quality (R01) Apply for RFA DA 10 004 Funding Number: RFA DA 10 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
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