Opportunity Information: Apply for PA 11 077
Apply for PA 11 077
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Mentored Clinical Scientist Research Career Development Award in Muscular Dystrophy Research (K08)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 13, 2010 and posted on Dec 13, 2010.
- Applicants must submit their applications by Nov 12, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Private institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Mentored Clinical Scientist Research Career Development Award in Muscular Dystrophy Research (K08) is an NIH funding opportunity designed to help clinically trained researchers build long-term, independent careers focused on muscular dystrophy. Led by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) in partnership with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the program emphasizes structured mentorship and protected research time so that early-career clinician-scientists can develop deep expertise, publish strong work, and transition into independent investigators who can lead their own research programs.
The main goal of the award is workforce development in muscular dystrophy research, with a clear focus on strengthening both the number of investigators entering the field and the quality of their training and research. The announcement highlights an urgent need for highly skilled, collaborative scientists who can work across disciplinary boundaries, which reflects the reality that muscular dystrophy research often requires integrating basic biology, translational studies, and clinical insight. In practice, the K08 structure supports individuals who are doing mentored laboratory-based research and need a formalized career development plan that blends research execution with targeted training (for example, in experimental approaches, disease mechanisms, biomarkers, or other relevant methods that position the candidate to become independent).
Scientifically, the scope covers basic, translational, and clinical research on muscular dystrophies, and it is intentionally broad to accommodate different entry points into the field as long as the work is clearly muscular dystrophy-focused and fits the K08 mentored clinical scientist model. The opportunity specifically notes that relevant diseases include Duchenne muscular dystrophy, myotonic dystrophy, facioscapulohumeral muscular dystrophy, and congenital muscular dystrophies, while also indicating that the program is not limited to only these conditions. The overall expectation is that awardees will emerge from the mentored period with stronger research skills, a clearer scientific niche, and a trajectory toward independent funding and leadership in muscular dystrophy research.
This opportunity uses the NIH K08 mechanism, which is a mentored career development award typically aimed at clinically trained professionals pursuing intensive, supervised research experiences as they develop into independent investigators. The announcement also notes that it is issued in parallel with companion funding opportunities of the same scientific scope that use other NIH mechanisms (including F32, K23, and K99). That parallel structure signals that NIH is trying to support a pipeline of researchers at different career stages and with different research emphases, while keeping the overarching muscular dystrophy mission consistent across the set of announcements.
From an administrative standpoint, this is a discretionary grant program with no cost-sharing or matching requirement. The opportunity was posted on December 13, 2010, and the original and final closing date listed is November 12, 2013, with an archive date of December 13, 2013, meaning it is no longer active as a current application call in this posted form. The funding is associated with CFDA numbers 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research) and 93.865 (Child Health and Human Development Extramural Research), reflecting the NIAMS and NICHD involvement.
Eligibility is broad on the institutional side and includes a wide range of organization types, such as public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, state governments, Native American tribal governments and organizations, and U.S. territories or possessions. The eligibility section also explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations, among others. This wide eligibility language is typical of NIH announcements and is meant to ensure that applicants across many institutional settings can participate, provided they meet NIH and FOA-specific requirements.
In short, PA-11-077 is an NIH mentored K08 career development opportunity aimed at clinically trained researchers committed to muscular dystrophy research, with the central purpose of building a stronger, more interdisciplinary pipeline of independent investigators capable of advancing basic, translational, and clinical progress across multiple muscular dystrophy subtypes.
FAQs: Mentored Clinical Scientist Research Career Development Award in Muscular Dystrophy Research (K08) (PA-11-077)
What is the Mentored Clinical Scientist Research Career Development Award in Muscular Dystrophy Research (K08)?
It is an NIH mentored career development funding opportunity using the K08 mechanism, intended to help clinically trained researchers build long-term, independent research careers focused on muscular dystrophy. The award emphasizes structured mentorship and protected research time so early-career clinician-scientists can deepen expertise, produce strong publications, and progress toward leading independent research programs.
Which NIH institutes lead this opportunity?
The opportunity is led by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) in partnership with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
What is the primary goal of this K08 award?
The primary goal is workforce development in muscular dystrophy research. The program is designed to increase both the number of investigators entering the field and the quality of their training and research, with an emphasis on developing highly skilled scientists who can collaborate across disciplinary boundaries.
What types of research does this award support?
The scientific scope covers basic, translational, and clinical research on muscular dystrophies. The scope is intentionally broad as long as the proposed work is clearly focused on muscular dystrophy and fits the K08 mentored clinical scientist model.
Which muscular dystrophy conditions are considered relevant under this opportunity?
The announcement specifically notes Duchenne muscular dystrophy, myotonic dystrophy, facioscapulohumeral muscular dystrophy, and congenital muscular dystrophies, while also stating that the program is not limited to only these conditions.
Who is this program intended for?
It is intended for clinically trained researchers who need a mentored, laboratory-based research experience supported by a formal career development plan. The focus is on early-career clinician-scientists developing toward independence in muscular dystrophy research.
What does "mentored" mean in the context of this K08?
In this context, "mentored" means the award supports a structured mentorship environment and a formalized career development plan, alongside protected time to conduct research. The overall expectation is that the candidate will strengthen research skills, define a clear scientific niche, and move toward independent funding and leadership.
What kinds of training or career development activities are emphasized?
The opportunity emphasizes a career development plan that blends research execution with targeted training. Examples mentioned include training in experimental approaches, disease mechanisms, biomarkers, and other relevant methods that position the candidate to become an independent investigator in muscular dystrophy research.
How does this opportunity fit into a broader NIH pipeline for muscular dystrophy research?
The announcement notes it was issued in parallel with companion funding opportunities of the same scientific scope that use other NIH mechanisms, including F32, K23, and K99. This signals an NIH strategy to support researchers at different career stages and with different research emphases while keeping the overarching muscular dystrophy mission consistent.
Is this opportunity still open for applications?
No. The opportunity was posted on December 13, 2010, and lists both an original and final closing date of November 12, 2013, with an archive date of December 13, 2013. In this posted form, it is no longer active as a current application call.
Does this grant require cost-sharing or matching funds?
No. The announcement describes the program as discretionary and states there is no cost-sharing or matching requirement.
What are the CFDA numbers associated with this funding opportunity?
The funding is associated with CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research) and CFDA 93.865 (Child Health and Human Development Extramural Research), reflecting NIAMS and NICHD involvement.
What types of organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, state governments, Native American tribal governments and organizations, and U.S. territories or possessions.
Are minority-serving institutions and community-based organizations included in the eligibility language?
Yes. The eligibility section explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations, among others.
What is the expected outcome for awardees by the end of the mentored period?
The expectation is that awardees will emerge with stronger research skills, a clearer scientific niche, and a trajectory toward independent funding and leadership in muscular dystrophy research, supported by the publications and expertise developed during the mentored period.
What is the name and identifier of this funding announcement?
The opportunity is identified as PA-11-077 and is titled the Mentored Clinical Scientist Research Career Development Award in Muscular Dystrophy Research (K08).
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Previous opportunity: NIH Pathway to Independence Award in Muscular Dystrophy Research (K99/R00)
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