Opportunity Information: Apply for PAR 08 175

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Millennium Promise Awards Non communicable Chronic Diseases Research Training Program (NCoD) (D43)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.989 International Research and Research Training.
  • This funding opportunity was created on Mar 23, 2010 and posted on Dec 2, 2008.
  • Applicants must submit their applications by Mar 23, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) Public/State Controlled Institutions of Higher Education in the U.S. with collaborating partners in LMICs Private Institutions of Higher Education in the U.S. with partners in LMICs and Non domestic (non U.S.) Entities (Foreign Organizations) in LMICs in collaboration with U.S. Institutions are also invited to apply Both U.S. and Foreign research institutions that have the infrastructure to train researchers in masters or doctoral level work are eligible and must have demonstrable ability to do such research training.
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Opportunity Summary:

The Millennium Promise Awards Non-communicable Chronic Diseases Research Training Program (NCoD) (D43), Funding Opportunity Number PAR-08-175, is a National Institutes of Health (NIH) discretionary grant program focused on strengthening long-term research training capacity in low- and middle-income countries (LMICs). The core aim is to develop well-trained researchers who can lead and sustain locally relevant research programs addressing major non-communicable diseases (NCDs) and their key risk factors. Rather than funding a single research project, the opportunity is centered on structured research training and career development, with an emphasis on building institutional capacity and expanding the pipeline of investigators who can conduct rigorous, publishable, and policy-relevant NCD research in LMIC settings.

The program targets training in several major NCD areas, specifically cancer; cerebrovascular disease including stroke; lung disease such as chronic obstructive pulmonary disease (COPD); and environmental contributors to chronic disease, including indoor air pollution. It also emphasizes obesity and lifestyle factors that drive NCD risk, along with the genetics of non-communicable diseases. In practice, this means proposed training programs are expected to prepare trainees to investigate both disease mechanisms and real-world drivers of disease burden, including behavioral, environmental, and potentially genetic determinants that are especially important in LMIC contexts where exposures and health systems differ from high-income countries.

A key feature of this opportunity is that applicants may be either U.S.-based (domestic) institutions or foreign (non-U.S.) institutions, but they must be able to demonstrate credible capacity to deliver research training at the masters or doctoral level. NIH is looking for institutions with the infrastructure and track record to train researchers, not organizations starting from scratch. Applicants must also show they already have active, relevant research programs in the targeted NCD fields, since the training is meant to be embedded in strong, ongoing research environments where trainees can gain hands-on experience, mentorship, and access to real datasets, laboratories, field sites, or clinical research settings. Collaboration is clearly encouraged: U.S. institutions applying are expected to work with LMIC partners, and LMIC institutions are invited to apply in collaboration with U.S. institutions, reflecting the intent to combine complementary expertise while ensuring the training remains grounded in LMIC priorities.

Eligibility is broad across the higher education and nonprofit landscape. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3) entities). The announcement also explicitly includes a wide range of institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, eligible federal agencies, and non-U.S. entities (foreign organizations). Overall, the eligibility language signals that NIH is willing to fund many kinds of institutions as long as they can demonstrate the required training capacity, appropriate partnerships, and an established research foundation in the targeted NCD areas.

From a funding and administrative standpoint, this is a grant mechanism under an education and health-oriented activity category, with no cost sharing or matching requirement. The estimated total funding listed is $1,500,000, with an anticipated seven awards, indicating a competitive program that will likely prioritize applications with clear training plans, strong mentorship structures, and credible institutional commitment to sustaining research training beyond the award period. The opportunity is tied to multiple CFDA numbers reflecting NIH’s cross-cutting interests (including nursing research, cancer prevention, neurosciences/neurological disorders, child health and human development, and international research and training), which underscores that the program sits at the intersection of several NIH research priorities rather than being confined to a single institute or discipline.

Key dates in the record show the opportunity was posted on December 2, 2008, with an original closing date of September 28, 2010, and a listed current closing date of March 23, 2010, with an archive date of April 23, 2010. While those dates indicate the specific announcement cycle is historical/archived, the summary still captures the intent and structure of the program: to create sustainable, high-quality research training pathways in LMICs for major chronic, non-communicable diseases and their determinants, through institutions that can demonstrate both training infrastructure and an active research base. For applicants or readers seeking full details, the announcement points to the NIH guide page (http://grants.nih.gov/grants/guide/pa-files/PAR-08-175.html) and provides NIH Office of Extramural Research (OER) webmaster contact information for access or technical issues.

Frequently Asked Questions (FAQs)

What is the Millennium Promise Awards Non-communicable Chronic Diseases Research Training Program (NCoD) (D43)?

It is a National Institutes of Health (NIH) discretionary grant program (Funding Opportunity Number PAR-08-175) focused on strengthening long-term research training capacity in low- and middle-income countries (LMICs). The goal is to develop well-trained researchers who can lead and sustain locally relevant research programs addressing major non-communicable diseases (NCDs) and their key risk factors.

Is this opportunity meant to fund a single research project?

No. The opportunity is centered on structured research training and career development rather than funding a single research project. The emphasis is on building institutional capacity and expanding the pipeline of investigators who can conduct rigorous, publishable, and policy-relevant NCD research in LMIC settings.

What is the core aim of the program?

The core aim is to develop researchers who can lead and sustain locally relevant NCD research programs in LMICs. The program prioritizes long-term training capacity, strong mentorship, and research environments that give trainees meaningful hands-on experience.

Which diseases and research areas does the training program target?

The program targets training in major NCD areas including cancer; cerebrovascular disease (including stroke); lung disease such as chronic obstructive pulmonary disease (COPD); and environmental contributors to chronic disease, including indoor air pollution. It also emphasizes obesity and lifestyle factors that drive NCD risk, along with the genetics of non-communicable diseases.

Does the program address risk factors and real-world drivers of disease, or only biological mechanisms?

It is intended to prepare trainees to investigate both disease mechanisms and real-world drivers of disease burden. This includes behavioral and environmental determinants, and potentially genetic determinants, especially those that are particularly important in LMIC contexts where exposures and health systems may differ from high-income settings.

Who is eligible to apply (U.S. vs. non-U.S. institutions)?

Applicants may be either U.S.-based (domestic) institutions or foreign (non-U.S.) institutions. In either case, the institution must be able to demonstrate credible capacity to deliver research training at the masters or doctoral level.

What level of training capacity must an applicant demonstrate?

Applicants must demonstrate credible capacity to deliver research training at the masters or doctoral level. NIH is looking for institutions with infrastructure and a track record to train researchers, rather than organizations starting from scratch.

Do applicants need to have existing research programs in the targeted NCD fields?

Yes. Applicants must show they already have active, relevant research programs in the targeted NCD fields. The training is expected to be embedded in strong, ongoing research environments where trainees can gain hands-on experience, mentorship, and access to real datasets, laboratories, field sites, or clinical research settings.

Are partnerships or collaborations required or encouraged?

Collaboration is clearly encouraged. U.S. institutions applying are expected to work with LMIC partners. LMIC institutions are invited to apply in collaboration with U.S. institutions. This reflects an intent to combine complementary expertise while keeping the training grounded in LMIC priorities.

What types of organizations are eligible applicants?

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3) entities). The announcement explicitly includes many institution types such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, eligible federal agencies, and non-U.S. entities (foreign organizations).

Does the program require cost sharing or matching funds?

No. The opportunity states there is no cost sharing or matching requirement.

How much funding is available and how many awards are anticipated?

The estimated total funding listed is $1,500,000, with an anticipated seven awards. This suggests a competitive program likely to prioritize strong training plans, mentorship structures, and institutional commitment to sustaining research training beyond the award period.

What does the D43 mechanism indicate about the nature of this grant?

Based on the description provided, the D43 mechanism is being used to support research training and capacity building, with an emphasis on structured training and career development in LMIC-focused NCD research rather than a single standalone research project.

What are the key dates for this funding opportunity?

The opportunity was posted on December 2, 2008. The original closing date is listed as September 28, 2010. A current closing date is listed as March 23, 2010, and the archive date is April 23, 2010. These dates indicate the specific announcement cycle is historical/archived.

Is this funding opportunity still open?

The dates provided indicate it is archived (archive date April 23, 2010). That suggests this specific announcement cycle is not currently open, even though the summary remains useful for understanding the program intent and structure.

Why are multiple CFDA numbers associated with this opportunity?

The opportunity is tied to multiple CFDA numbers reflecting NIH cross-cutting interests (including nursing research, cancer prevention, neurosciences/neurological disorders, child health and human development, and international research and training). This underscores that the program sits at the intersection of several NIH priorities rather than being limited to a single institute or discipline.

Where can applicants or readers find the official NIH announcement page?

The announcement points to the NIH guide page at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-175.html

Who is listed as a contact for access or technical issues related to the announcement?

The information provided notes NIH Office of Extramural Research (OER) webmaster contact information is available for access or technical issues.

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