Minority Based Community Clinical Oncology Program Groups (U10) | Apply Online

Opportunity Summary:

The Minority Based Community Clinical Oncology Program Groups (U10) grant opportunity (Funding Opportunity Number RFA-CA-10-012) is a National Institutes of Health, National Cancer Institute (NCI) funding announcement designed to expand access to NCI-sponsored cancer clinical trials in communities that serve large minority populations. At its core, the program is meant to bring research opportunities and cutting-edge cancer care options closer to where minority patients already receive care, by enabling practicing community oncologists and their organizations to participate directly in national clinical trials focused on cancer prevention, cancer control, and cancer treatment. By supporting these community-based physician networks as a national resource, NCI aims to strengthen the research capacity of providers caring for minority populations and to ensure that trial participation more accurately reflects the diversity of the U.S. population.

A central goal of the Minority Based CCOP model is to increase minority patient enrollment (accrual) into NCI-approved clinical trials. This matters because clinical trial participation has historically been lower among minority and underserved groups for many reasons, including limited trial availability in local settings, logistical barriers, and lack of established trial infrastructure in community practices. Through this program, NCI connects community oncologists and their patients to a broader clinical trials system that includes cancer centers, major university centers, and established community programs. That linkage is intended to speed the transfer of proven research findings into real-world practice in minority communities, so new prevention approaches, symptom-management strategies, and treatment advances reach patients sooner and become part of routine community care.

This opportunity sits within the larger Community Clinical Oncology Program (CCOP) Network, which began in 1983 to promote state-of-the-art cancer clinical trials with strong participation from community oncologists and the populations they serve. The CCOP Network is described as having three main components, each with its own funding announcement: Minority Based CCOPs (the focus of this FOA), standard CCOP Groups (also called CCOPs), and CCOP Research Bases. In practical terms, the Minority Based CCOPs are the community-facing organizations and physician networks that recruit and enroll patients into trials. The CCOP Research Bases are the entities that design and run those trials, handle data management and analysis, and publish results. Research Bases must be located at either an NCI-supported Clinical Cooperative Group or an NCI-designated Cancer Center, ensuring the trials are anchored in established research leadership while enrollment can occur broadly in community settings.

The mission of the CCOP Network, as reflected in this announcement, is threefold. First, it aims to accelerate the development of interventions that prevent cancer, treat cancer, and address cancer-related symptoms by increasing patient enrollment into well-run trials. Second, it seeks to improve the quality of cancer care in community settings by encouraging adoption of evidence-based practices that emerge from those trials. Third, it explicitly prioritizes increasing participation of minority and underserved patients in clinical trials and related research, addressing both equity and the scientific need for results that apply across diverse populations.

Funding is provided through the NIH U10 cooperative agreement mechanism, which generally indicates a collaborative relationship between the awardee and the federal government, with NIH/NCI having substantial programmatic involvement compared with a standard grant. The announcement is categorized as discretionary funding and is listed under broad health and education activity areas, reflecting its dual emphasis on clinical research participation and the spread of best practices into community care. The estimated total funding level is $2,000,000 with an expected five awards, and there is no cost-sharing or matching requirement stated for applicants.

Eligibility is broad and includes many types of institutions and organizations that could plausibly support a community oncology clinical trials network. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations other than small businesses, Native American tribal governments and tribal organizations, U.S. territories or possessions, and a range of mission-focused institutions and community entities. The announcement specifically notes eligibility for Alaska Native and Native Hawaiian Serving Institutions, Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and eligible federal agencies. This wide eligibility aligns with the program purpose of meeting minority communities where they are, using local and culturally connected institutions as potential anchors for participation.

Key administrative details reflect that this was a time-limited opportunity posted July 16, 2010, with an original and final closing date of September 16, 2010, and an archive date of October 17, 2010. The opportunity is associated with multiple CFDA numbers spanning the cancer research continuum, including prevention, detection and diagnosis, treatment, biology, cancer centers support, research manpower, and cancer control, which underscores that the supported clinical trial activity can touch many domains of cancer research rather than being confined to a single disease area or research type. The full announcement was made available through the NIH Grants Guide (link provided in the source), and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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