Opportunity Information: Apply for CDC RFA GH15 1612
Apply for CDC RFA GH15 1612
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "National Stop Transmission of Polio (NSTOP) initiative supporting polio eradication in Africa" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318 Protecting and Improving Health Globally Building and Strengthening Public Health Impact, Systems, Capacity and Securit.
- This funding opportunity was created on Jan 8, 2015 and posted on Jan 8, 2015.
- Applicants must submit their applications by Mar 10, 2015 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $90,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $18,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Africa Field Epidemiology Network (AFENET)
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Opportunity Summary:
The National Stop Transmission of Polio (NSTOP) initiative is a CDC-funded cooperative agreement designed to strengthen and expand Africa-based capacity to finish polio eradication work, with a primary focus on Nigeria and additional support to outbreak and high-risk countries in Central and East Africa. The opportunity is grounded in the fact that polio remains a serious, potentially fatal disease with no cure, and that at the time of the announcement it was treated by WHO as a Public Health Emergency of International Concern. Even though vaccines are safe and effective, the grant frames the main bottleneck as operational capacity on the ground: many local and national public health staff in endemic, outbreak, and at-risk countries lack enough specialized expertise to carry out high-quality immunization and surveillance activities consistently and urgently enough to stop transmission.
This funding directly supports the Global Polio Eradication Initiative (GPEI), where CDC is one of the core partner agencies providing technical and financial assistance. The grant aligns with the GPEI approach built around four main strategies: strengthening routine immunization systems, conducting supplementary immunization activities (mass campaigns), maintaining sensitive surveillance for acute flaccid paralysis (AFP) to rapidly detect potential poliovirus circulation, and implementing targeted "mop-up" campaigns to close immunity gaps in specific locations where transmission risk remains high. The program narrative emphasizes that as long as Nigeria remains endemic and outbreaks continue to occur in parts of Central and East Africa, the entire African region and the wider world remain at risk from cross-border spread, making sustained interruption of transmission the overriding goal.
A central feature of NSTOP is workforce development using a field epidemiology training network model. The initiative, launched jointly by CDC and the Africa Field Epidemiology Network (AFENET) in 2012, is built to place skilled personnel closer to where outbreaks begin and where immunization performance succeeds or fails: at the lowest administrative levels and within communities. In practical terms, the grant is meant to build local capacity to plan and manage vaccination campaigns, improve supervision and data use, strengthen AFP surveillance and case investigation, and support rapid response and targeted interventions in underperforming or high-risk areas. The logic is that trained and embedded public health workers improve quality and accountability of eradication operations, which is essential for reaching the last pockets of transmission and preventing reintroductions.
Administratively, this is a discretionary CDC cooperative agreement (Funding Opportunity Number CDC RFA GH15-1612) under CFDA 93.318, focused on protecting and improving health globally by building public health systems and capacity. The opportunity anticipated a single award, with an estimated total funding level of $90,000,000 and an award ceiling of $18,000,000 (no award floor listed). There was no cost sharing or matching requirement. Eligibility was restricted to AFENET, reflecting the intent to scale an existing CDC-AFENET platform rather than create a new implementing structure. The notice was posted January 8, 2015, with applications due March 10, 2015 (11:59 p.m. ET), and the announcement archived April 9, 2015. A CDC contact was provided for access issues (Andrew Stein, vpd4@cdc.gov).
Frequently Asked Questions (FAQs): CDC RFA GH15-1612 - National Stop Transmission of Polio (NSTOP)
What is the NSTOP grant opportunity?
The National Stop Transmission of Polio (NSTOP) initiative is a CDC-funded cooperative agreement intended to strengthen and expand Africa-based capacity to finish polio eradication work. The program is designed to improve the on-the-ground operational capacity needed to consistently deliver high-quality immunization and surveillance activities urgently enough to stop poliovirus transmission.
Who is the funder for this opportunity?
The funder is the U.S. Centers for Disease Control and Prevention (CDC). This opportunity is offered as a CDC discretionary cooperative agreement.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is CDC RFA GH15-1612.
What CFDA number is associated with this cooperative agreement?
The opportunity is listed under CFDA 93.318.
What is the main public health issue this program addresses?
The program addresses polio, described in the opportunity as a serious and potentially fatal disease with no cure. At the time of the announcement, polio was treated by the World Health Organization (WHO) as a Public Health Emergency of International Concern.
If vaccines are safe and effective, why is additional funding needed?
The opportunity identifies the primary bottleneck as operational capacity on the ground. It states that many local and national public health staff in endemic, outbreak, and at-risk countries lack sufficient specialized expertise to carry out high-quality immunization and surveillance activities consistently and with enough urgency to stop transmission.
How does NSTOP relate to the Global Polio Eradication Initiative (GPEI)?
This funding directly supports the Global Polio Eradication Initiative (GPEI). The CDC is described as one of the core partner agencies in GPEI, providing technical and financial assistance.
What strategies does the grant align with under the GPEI approach?
The opportunity aligns with four main GPEI strategies:
- Strengthening routine immunization systems
- Conducting supplementary immunization activities (mass campaigns)
- Maintaining sensitive surveillance for acute flaccid paralysis (AFP) to rapidly detect potential poliovirus circulation
- Implementing targeted "mop-up" campaigns to close immunity gaps in specific locations where transmission risk remains high
What is the primary geographic focus of NSTOP?
The primary focus is Nigeria, with additional support to outbreak and high-risk countries in Central and East Africa.
Why is Nigeria emphasized in the program narrative?
The narrative emphasizes that as long as Nigeria remains endemic and outbreaks continue in parts of Central and East Africa, the entire African region and the wider world remain at risk due to cross-border spread. Sustained interruption of transmission is presented as the overriding goal.
What is described as a central feature of NSTOP?
A central feature is workforce development using a field epidemiology training network model. The initiative is built to place skilled personnel closer to where outbreaks begin and where immunization performance succeeds or fails, specifically at the lowest administrative levels and within communities.
When was NSTOP launched, and with whom?
NSTOP was launched jointly by CDC and the Africa Field Epidemiology Network (AFENET) in 2012.
What types of activities does the grant intend to strengthen?
Based on the opportunity description, NSTOP is meant to build local capacity to:
- Plan and manage vaccination campaigns
- Improve supervision and data use
- Strengthen AFP surveillance and case investigation
- Support rapid response and targeted interventions in underperforming or high-risk areas
What is AFP surveillance and why is it included?
The opportunity highlights maintaining sensitive surveillance for acute flaccid paralysis (AFP) as a key strategy to rapidly detect potential poliovirus circulation. AFP surveillance and case investigation are included as core operational capabilities to help identify and respond to transmission risk quickly.
What are "supplementary immunization activities" in this context?
The grant describes supplementary immunization activities as mass campaigns conducted in addition to routine immunization to rapidly boost population immunity.
What are "mop-up" campaigns?
The opportunity describes "mop-up" campaigns as targeted immunization efforts designed to close immunity gaps in specific locations where transmission risk remains high.
What is the intended impact of training and embedding public health workers locally?
The opportunity states that trained and embedded public health workers improve quality and accountability of eradication operations. This is presented as essential for reaching the last pockets of transmission and preventing reintroductions.
What type of award mechanism is this?
This is a CDC cooperative agreement. The opportunity is described as discretionary, and it is framed as supporting public health systems and capacity building to protect and improve health globally.
How many awards were anticipated?
The opportunity anticipated a single award.
What was the estimated total funding amount for this opportunity?
The estimated total funding level was $90,000,000.
What was the award ceiling?
The award ceiling was $18,000,000.
Was there an award floor?
No award floor was listed in the information provided.
Was cost sharing or matching required?
No. The opportunity states there was no cost sharing or matching requirement.
Who was eligible to apply?
Eligibility was restricted to the Africa Field Epidemiology Network (AFENET). The opportunity notes this restriction reflected an intent to scale an existing CDC-AFENET platform rather than create a new implementing structure.
When was the notice posted?
The notice was posted on January 8, 2015.
What was the application deadline?
Applications were due March 10, 2015 at 11:59 p.m. Eastern Time (ET).
When was the opportunity archived?
The announcement was archived on April 9, 2015.
Who was the CDC contact listed for access issues?
The contact listed was Andrew Stein (vpd4@cdc.gov).
What is the overarching goal highlighted by the opportunity?
The opportunity frames sustained interruption of poliovirus transmission as the overriding goal, emphasizing that ongoing endemic transmission and outbreaks pose cross-border risks to the region and beyond.
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