Opportunity Information: Apply for RFA RM 14 017

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIH Science of Behavior Change Resource and Coordinating Center (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
  • This funding opportunity was created on Jan 8, 2015 and posted on Jan 8, 2015.
  • Applicants must submit their applications by Mar 20, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Independent school districts State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments Small businesses For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIH Science of Behavior Change Resource and Coordinating Center (RCC) opportunity (RFA-RM-14-017) is a Cooperative Agreement (U24) funded through the NIH Common Fund, a program designed to back cross-cutting research efforts that can have unusually large, field-shaping impact. The Common Fund emphasis is on encouraging bold and innovative work, including approaches that may be higher-risk but could unlock rapid progress on long-standing scientific problems. In this case, the focus is behavior change science, with an explicit goal of improving how behavioral interventions are designed and tested.

This FOA funds one award to establish and operate the SOBC Resource and Coordinating Center, which functions as the central hub for the broader SOBC Program. The RCC is expected to coordinate the activities of five to nine companion UH2/UH3 Target Validation Projects that are funded under three related FOAs (RFA-RM-14-018, RFA-RM-14-019, and RFA-RM-14-020). Those projects concentrate on identifying and validating behavior-change targets in three domains: (1) self-regulation, (2) stress reactivity and stress resilience, and (3) interpersonal and social processes. The RCC is not described as conducting those individual target validation studies itself so much as enabling them to operate as a coherent, collaborative program with shared methods, aligned milestones, and program-wide learning.

A core scientific theme running through the announcement is the "experimental medicine" approach applied to behavior change research. In practical terms, that means pushing the field toward specifying mechanistic targets, developing and validating assays that can measure those targets, and then using interventions to deliberately engage those targets and verify that target engagement leads to meaningful behavioral outcomes. The RCC is positioned to provide national leadership for these coordinated efforts, particularly around validating assays for behavior change, and it is charged with meeting five specific objectives laid out in the full FOA. While the short description does not list those five objectives verbatim, the intent is clear: standardize and support rigorous, program-wide methods and infrastructure so the separate projects produce comparable, cumulative evidence rather than isolated findings.

Operationally, the RCC is also responsible for the organizational backbone of the SOBC Program. It serves as the central resource for planning and running meetings and other program activities, and it provides support for SOBC governance and oversight structures, including the Steering Committee and the External Scientific Panel, as well as any subcommittees established under the Steering Committee. Because this is a cooperative agreement, NIH involvement is typically more collaborative than in a standard grant mechanism, with substantial programmatic coordination expected between NIH and awardees.

From an eligibility and administrative standpoint, the opportunity falls under the health funding activity category and is associated with CFDA 93.310 (Trans-NIH Research Support). Cost sharing is not required. A wide range of applicant organizations are eligible, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), state and local governmental entities, special district governments, tribal governments and tribally controlled institutions, faith-based or community-based organizations, small businesses, and for-profit organizations (including those other than small businesses). The FOA explicitly excludes non-U.S. (foreign) institutions as direct applicants, though non-U.S. components of U.S. organizations may apply, and foreign components (as defined by NIH policy) are allowed. The funding opportunity was posted January 8, 2015, with an original and current closing date of March 20, 2015, and an archive date of April 20, 2015.

Finally, NIH directs interested parties to the SOBC program website and FAQ page for updates and clarifications tied to this FOA and its companion announcements. The full text of the funding announcement is available via the NIH grants guide link provided in the source, and NIH’s Office of Extramural Research (OER) webmaster contact is listed for access or technical issues.

Frequently Asked Questions (FAQs)

What is the NIH Science of Behavior Change Resource and Coordinating Center (RCC) opportunity?

This opportunity (RFA-RM-14-017) funds a single Science of Behavior Change (SOBC) Resource and Coordinating Center (RCC) under a Cooperative Agreement (U24). The RCC is intended to serve as the central hub that coordinates and supports the broader SOBC Program.

Which NIH funding mechanism is used for this award?

The award mechanism is a Cooperative Agreement (U24). Cooperative agreements typically involve more NIH collaboration and programmatic coordination than standard grant mechanisms.

How many awards will be made under this FOA?

This FOA funds one award to establish and operate the SOBC Resource and Coordinating Center (RCC).

What is the role of the RCC within the SOBC Program?

The RCC functions as the central resource and coordinating hub for the SOBC Program. It is expected to enable a coherent, collaborative program by supporting shared methods, aligned milestones, and program-wide learning across companion projects.

Does the RCC conduct the individual Target Validation research studies?

Based on the description provided, the RCC is not presented as conducting the individual target validation studies itself. Instead, it supports and coordinates the companion Target Validation Projects so they operate as an integrated program and produce comparable, cumulative evidence.

What other projects does the RCC coordinate?

The RCC is expected to coordinate five to nine companion UH2/UH3 Target Validation Projects funded under three related FOAs: RFA-RM-14-018, RFA-RM-14-019, and RFA-RM-14-020.

What scientific areas do the companion Target Validation Projects focus on?

The companion projects focus on identifying and validating behavior-change targets in three domains: (1) self-regulation, (2) stress reactivity and stress resilience, and (3) interpersonal and social processes.

What is the "experimental medicine" approach in the context of this program?

In this FOA, the experimental medicine approach emphasizes specifying mechanistic targets, developing and validating assays to measure those targets, and using interventions to deliberately engage those targets to verify whether target engagement produces meaningful behavioral outcomes.

What is the main purpose of emphasizing assays and target engagement?

The intent is to strengthen rigor and comparability across projects by validating how behavior-change targets are measured (assays) and by testing whether interventions actually engage those targets in ways that lead to behavioral outcomes.

What is the RCC expected to provide scientifically?

The RCC is positioned to provide national leadership for coordinated SOBC efforts, particularly around validating assays for behavior change, and to support rigorous, program-wide methods and infrastructure that help the program generate comparable, cumulative evidence.

Are there specific objectives the RCC must meet?

Yes. The FOA references five specific objectives for the RCC. The short description provided here does not list them verbatim, but it indicates the objectives focus on standardizing and supporting rigorous program-wide methods and infrastructure across the SOBC Program.

What operational responsibilities does the RCC have?

The RCC provides the organizational backbone for the SOBC Program, including planning and running meetings and other program activities, and supporting program governance and oversight structures.

Which governance and oversight groups does the RCC support?

The RCC provides support for SOBC governance and oversight structures, including the Steering Committee and the External Scientific Panel, as well as any subcommittees established under the Steering Committee.

What is the funding source for this opportunity?

The RCC is funded through the NIH Common Fund, which supports cross-cutting research efforts intended to have unusually large, field-shaping impact.

What is the NIH Common Fund emphasis described in this opportunity?

The Common Fund emphasis is on encouraging bold and innovative work, including approaches that may be higher-risk but could enable rapid progress on long-standing scientific problems. Here, that emphasis is applied to behavior change science to improve how behavioral interventions are designed and tested.

Is cost sharing required?

No. Cost sharing is not required for this opportunity.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA 93.310 (Trans-NIH Research Support).

What types of organizations are eligible to apply?

A wide range of applicant organizations are eligible, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), state and local governmental entities, special district governments, tribal governments and tribally controlled institutions, faith-based or community-based organizations, small businesses, and for-profit organizations (including those other than small businesses).

Are non-U.S. (foreign) institutions eligible to apply directly?

No. The FOA explicitly excludes non-U.S. (foreign) institutions as direct applicants.

Are any foreign components allowed under this opportunity?

Yes. Non-U.S. components of U.S. organizations may apply, and foreign components (as defined by NIH policy) are allowed.

What is the posting date for this FOA?

The funding opportunity was posted on January 8, 2015.

What is the application closing date?

The original and current closing date is March 20, 2015.

When was the FOA archived?

The archive date is April 20, 2015.

Where can applicants find updates or clarifications related to this FOA?

NIH directs interested parties to the SOBC program website and its FAQ page for updates and clarifications tied to this FOA and its companion announcements.

Where can the full funding announcement be found?

The full text of the funding announcement is available via the NIH grants guide link referenced in the source information for this opportunity.

Who should be contacted for access or technical issues?

The NIH Office of Extramural Research (OER) webmaster contact is listed for access or technical issues related to the announcement materials.

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