Opportunity Information: Apply for PAR 15 340
Apply for PAR 15 340
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control.
- This funding opportunity was created on Sep 1, 2015 and posted on Sep 1, 2015.
- Applicants must submit their applications by Nov 10, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public housing authorities/Indian housing authorities Special district governments County governments For profit organizations other than small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21), Funding Opportunity Number PAR-15-340, is a National Institutes of Health (NIH) National Cancer Institute (NCI) grant program designed to spark new and early-stage cancer research ideas. It is built specifically for exploratory and developmental projects that are still in their conceptual or proof-of-principle phase, where the main goal is to test fresh hypotheses, generate preliminary data, or establish feasibility for approaches that are not yet ready for larger, longer-term mechanisms. The R21 format is meant to give researchers room to try bold directions that may carry higher scientific risk than a typical hypothesis-driven project, with the understanding that successful work could open up a new line of investigation or shift how a problem is approached in cancer research.
In practical terms, this opportunity supports research across the full landscape of cancer science, including biomedical, behavioral, and clinical domains. The program is broad by design, covering areas reflected in the listed CFDA numbers: cancer cause and prevention (93.393), detection and diagnosis (93.394), treatment (93.395), biology (93.396), and control (93.399). Projects funded under this announcement might focus on developing novel techniques or tools, creating or refining agents and interventions, advancing new methodologies, building innovative models, or piloting applications that could later scale into more definitive studies. The emphasis is on innovation and potential impact rather than on having an already fully mature research plan, which makes it especially relevant for investigators who are proposing something unconventional, cross-disciplinary, or technically uncertain but potentially transformative.
The award information provided indicates an award ceiling of $200,000, aligning with the typical small, early-stage budget expectations of R21 grants. There is no cost sharing or matching requirement, which means applicants are not required to contribute their own funds as a condition of receiving an award. The opportunity is categorized as discretionary funding, uses the grant funding instrument, and is associated with an education and health funding activity category, consistent with NIH research support that also develops scientific capability and knowledge.
Eligibility is intentionally expansive and includes a wide range of organizational types. Eligible applicants span federal, state, local, and tribal governments; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (including those with 501(c)(3) status and certain nonprofits without 501(c)(3) status, as described); for-profit organizations other than small businesses; small businesses; independent school districts; public housing authorities and Indian housing authorities; special district governments; and regional organizations. The announcement also explicitly includes many institution types often highlighted for broad participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs). Importantly, it also allows non-domestic (non-U.S.) entities (foreign organizations) and U.S. territories or possessions, signaling that NCI is open to strong exploratory cancer research ideas regardless of geography, as long as the applicant organization fits the program rules.
Key administrative details in the source data show the opportunity was posted and created on September 1, 2015, with an original and current closing date of November 10, 2015, and an archive date of December 11, 2015. The full announcement was hosted through the NIH Grants Guide and is referenced via the additional information link at http://grants.nih.gov/grants/guide/pa-files/PAR-15-340.html. For technical issues accessing the announcement or linking problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, PAR-15-340 is best understood as a flexible NCI-wide R21 entry point for new cancer research directions: it is meant to help investigators move from an interesting, potentially high-impact idea to a credible early demonstration, often enabling a later transition into larger, more definitive funding mechanisms once feasibility and initial evidence are established.
FAQs: NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21) - PAR-15-340
What is PAR-15-340?
PAR-15-340 is the NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21), a National Institutes of Health (NIH) National Cancer Institute (NCI) funding opportunity designed to spark new and early-stage cancer research ideas using the R21 grant mechanism.
What is the goal of the NCI Omnibus R21 program?
The goal is to support exploratory and developmental projects that are still in the conceptual or proof-of-principle stage. The program is intended to help researchers test new hypotheses, generate preliminary data, or establish feasibility for approaches that are not yet ready for larger and longer-term funding mechanisms.
What types of projects fit the R21 format under this opportunity?
This opportunity is built for early-stage, exploratory work where innovation and potential impact are emphasized over having a fully mature research plan. It is a good fit for bold directions that may carry higher scientific risk than a typical hypothesis-driven project, as long as successful results could open a new line of investigation or shift how a cancer research problem is approached.
Does this program support high-risk, high-reward research?
Yes. The R21 format is described as providing room to try bold directions that may involve higher scientific risk, with the expectation that successful exploratory work can lead to new research directions or future, more definitive studies.
What research areas are covered?
The program supports research across the full landscape of cancer science, including biomedical, behavioral, and clinical domains. It is broad by design and aligns with the listed CFDA areas: cancer cause and prevention (93.393), detection and diagnosis (93.394), treatment (93.395), biology (93.396), and control (93.399).
What kinds of activities or outputs might be funded?
Examples of the kinds of projects described include developing novel techniques or tools, creating or refining agents and interventions, advancing new methodologies, building innovative models, or piloting applications that could later scale into more definitive studies.
Is the program limited to a specific cancer topic or NCI division?
Based on the description, it is an NCI-wide "omnibus" R21 entry point intended to be flexible and broad, supporting exploratory cancer research across many areas rather than being restricted to a single narrow topic.
What is the maximum award amount (award ceiling)?
The award ceiling listed is $200,000, consistent with the R21 being a smaller, early-stage budget mechanism.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to contribute their own funds as a condition of receiving an award.
What type of funding is this (grant vs. contract), and how is it categorized?
It is discretionary funding that uses the grant funding instrument. It is associated with an education and health funding activity category, consistent with NIH research support and scientific capability development.
Who is eligible to apply?
Eligibility is expansive and includes many organizational types, including: federal, state, local, and tribal governments; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain nonprofits without 501(c)(3) status, as described); for-profit organizations other than small businesses; small businesses; independent school districts; public housing authorities and Indian housing authorities; special district governments; and regional organizations.
Are minority-serving institutions explicitly included as eligible applicants?
Yes. The announcement explicitly includes institution types often highlighted for broad participation, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Can non-U.S. organizations apply?
Yes. The opportunity allows non-domestic (non-U.S.) entities (foreign organizations) and also includes U.S. territories or possessions, indicating eligibility is not limited strictly to U.S.-based organizations as long as they meet program rules.
When was this funding opportunity posted?
The opportunity was posted (and created) on September 1, 2015.
What was the application closing date for PAR-15-340?
The original and current closing date listed is November 10, 2015.
Is PAR-15-340 still open?
Based on the dates provided, it is not open. The opportunity shows a closing date of November 10, 2015, and an archive date of December 11, 2015.
Where can I find the full announcement details?
The full announcement is hosted through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-15-340.html.
Who do I contact for technical issues with the announcement link or access?
For technical issues accessing the announcement or problems with linking, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the intended outcome of an R21 project funded under this opportunity?
The intended outcome is to move a promising, potentially high-impact idea to an early demonstration of feasibility or proof-of-principle, often enabling a later transition to larger and more definitive funding mechanisms once preliminary evidence is established.
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