Opportunity Information: Apply for PAR 12 145
Apply for PAR 12 145
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research.
- This funding opportunity was created on Mar 19, 2013 and posted on Mar 29, 2012.
- Applicants must submit their applications by Mar 19, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education State governments City or township governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NCI Exploratory/Developmental Research Grant Program, commonly referred to as the NCI Omnibus R21 (Funding Opportunity Number PAR-12-145), is a National Institutes of Health funding opportunity run through the National Cancer Institute. Its main purpose is to help researchers launch new, early-stage cancer research ideas across the full range of cancer-related topics. The R21 mechanism is specifically designed for exploratory and developmental work, meaning it is meant to support projects that are still in the early, conceptual phase rather than fully mature programs of research. In practice, this makes it a good fit for investigators who want to test a bold hypothesis, gather initial proof-of-concept data, or try out a new approach that could later be expanded into a larger study.
A defining feature of this opportunity is that it explicitly welcomes higher-risk ideas. NCI highlights that R21 projects may involve considerable risk, but the tradeoff is that they may produce outsized benefits: a breakthrough in a particular area of cancer research or the creation of a novel tool, technique, methodology, agent, model, or application. The scope is intentionally broad and includes biomedical, behavioral, and clinical cancer research. That means applications could range from lab-based studies (like new experimental models of tumor biology), to technology development (like detection or imaging methods), to intervention-focused concepts (like new therapeutic strategies), and also behavioral or implementation concepts that could influence prevention, screening, or patient outcomes.
From the source details provided, this is a discretionary grant program using the grant funding instrument type, and it sits within health and education-related funding activity categories. It is mapped to multiple CFDA numbers that cover major NCI research areas: 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), 93.395 (Cancer Treatment Research), and 93.396 (Cancer Biology Research). Cost sharing or matching is not required, which is helpful for applicants that do not have flexible institutional funds to contribute.
The opportunity lists an award ceiling of $200,000, indicating the maximum award amount reflected in the synopsis. While the summary does not provide the full set of NIH budgeting rules, the ceiling signals that this mechanism is intended for smaller, targeted projects that can be executed efficiently to produce an early readout, feasibility demonstration, or initial dataset that positions the work for future expansion.
Eligibility is expansive and includes a wide variety of organization types. Eligible applicants include state, county, city/township, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories as stated); for-profit organizations (including small businesses and other for-profits); public housing authorities and Indian housing authorities; and Native American tribal governments and tribal organizations (including both federally recognized tribal governments and other tribal entities). The eligibility notes further clarify that additional eligible applicants may include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible agencies of the federal government. Importantly, foreign participation is allowed: non-U.S. entities (foreign institutions) may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as NIH defines them) are permitted. This broad eligibility aligns with the program’s goal of stimulating innovative cancer research wherever strong ideas and capable teams exist.
The key dates in the record show that the opportunity was posted on March 29, 2012, with an original closing date of September 7, 2015. The listing also includes a current closing date of March 19, 2013, and it is archived with an archive date of April 19, 2013. Those date fields reflect how the opportunity was cataloged in the provided dataset, and the archive status indicates that this specific listing is no longer active in that form, even though the R21 mechanism itself continues to exist across NIH in various announcements.
For applicants who want to review the full announcement details, the synopsis points to the NIH grants guide page: http://grants.nih.gov/grants/guide/pa-files/PAR-12-145.html. Contact support in the listing is routed through the NIH Office of Extramural Research webmaster (FBOWebmaster@OD.NIH.GOV), particularly for issues accessing the announcement or linking problems, which suggests the contact is geared toward technical access rather than scientific program questions.
Overall, PAR-12-145 describes a flexible, early-stage NCI grant mechanism meant to spark new directions in cancer research, especially ideas that are innovative and potentially high impact but not yet ready for a larger-scale award. It is structured to help teams develop and validate concepts, produce enabling tools or methods, and open up new lines of inquiry that could materially influence prevention, detection, diagnosis, treatment, and the underlying biology of cancer.
FAQs: NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21) - PAR-12-145
What is the NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21)?
It is a National Institutes of Health (NIH) funding opportunity run through the National Cancer Institute (NCI) that uses the R21 grant mechanism to support exploratory and developmental cancer research projects. The specific Funding Opportunity Number referenced is PAR-12-145.
What is the main purpose of PAR-12-145?
The purpose is to help researchers launch new, early-stage cancer research ideas across a broad range of cancer-related topics, especially projects that are still conceptual and need support to establish feasibility, proof of concept, or initial data.
What does the R21 mechanism support?
The R21 mechanism is designed for exploratory and developmental work. It supports early, conceptual projects rather than fully mature programs of research.
Is this opportunity intended for high-risk, high-reward ideas?
Yes. A defining feature of this opportunity is that it explicitly welcomes higher-risk ideas. NCI notes that R21 projects may involve considerable risk, with the potential for outsized benefits such as breakthroughs or the creation of novel tools, techniques, methodologies, agents, models, or applications.
What types of cancer research topics are included in the scope?
The scope is intentionally broad and includes biomedical, behavioral, and clinical cancer research across the full range of cancer-related topics.
What are some examples of the kinds of projects that may fit this program?
Based on the description, projects could include lab-based studies such as new experimental models of tumor biology, technology development such as detection or imaging methods, intervention-focused concepts such as new therapeutic strategies, and behavioral or implementation concepts that could influence prevention, screening, or patient outcomes.
What is the funding instrument type for this opportunity?
This is a discretionary grant program using the grant funding instrument type.
Which funding activity categories does this opportunity fall under?
It is listed within health and education-related funding activity categories.
Which CFDA numbers are associated with this opportunity?
The opportunity is mapped to multiple CFDA numbers covering major NCI research areas: 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), 93.395 (Cancer Treatment Research), and 93.396 (Cancer Biology Research).
Is cost sharing or matching required?
No. Cost sharing or matching is not required for this opportunity.
What is the maximum award amount listed for PAR-12-145?
The award ceiling listed in the synopsis is $200,000, which reflects the maximum award amount in the provided record.
What does the $200,000 award ceiling suggest about project size and intent?
It suggests the mechanism is intended for smaller, targeted projects that can be executed efficiently to generate an early readout, feasibility demonstration, or initial dataset that can position the work for later expansion.
Which organizations are eligible to apply?
Eligibility is broad and includes: state, county, city/township, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories as stated); for-profit organizations (including small businesses and other for-profits); public housing authorities and Indian housing authorities; and Native American tribal governments and tribal organizations (including federally recognized tribal governments and other tribal entities).
Are minority-serving institutions and other special categories of applicants mentioned as eligible?
Yes. The eligibility notes indicate additional eligible applicants may include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible agencies of the federal government.
Are for-profit entities eligible to apply?
Yes. For-profit organizations are listed as eligible, including small businesses and other for-profit entities.
Are nonprofit organizations eligible to apply?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible, with a note that higher education institutions are excluded from those nonprofit categories as stated in the provided description.
Can foreign (non-U.S.) institutions participate?
Yes. Foreign participation is allowed. Non-U.S. entities (foreign institutions) may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as NIH defines them) are permitted.
Who runs this funding opportunity?
The program is run through the National Cancer Institute (NCI) within the National Institutes of Health (NIH).
What were the key dates listed for this opportunity?
The record shows the opportunity was posted on March 29, 2012. It lists an original closing date of September 7, 2015, a current closing date of March 19, 2013, and it is archived with an archive date of April 19, 2013.
Is PAR-12-145 still active?
The listing is marked as archived, and the archive status indicates that this specific listing is no longer active in that form.
Where can applicants find the full announcement details?
The synopsis points to the NIH Grants Guide page for the full announcement: http://grants.nih.gov/grants/guide/pa-files/PAR-12-145.html
Who is listed as the contact for support in the record?
The listing routes contact support through the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
What kind of help is the listed contact likely intended for?
Based on the description, the contact appears geared toward technical access issues (for example, problems accessing the announcement or linking issues) rather than scientific or programmatic questions.
How would you summarize what PAR-12-145 is trying to achieve?
It is designed to spark new directions in cancer research by funding flexible, early-stage projects that are innovative and potentially high impact, including higher-risk ideas that are not yet ready for a larger award, and that could influence prevention, detection, diagnosis, treatment, or understanding of cancer biology.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 12 145) also looked into and applied for these:
| Funding Opportunity |
|---|
| NCI Small Grants Program for Cancer Research (NCI Omnibus R03) Apply for PAR 12 144 Funding Number: PAR 12 144 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanisms of Alcohol associated Cancers (R01) Apply for PA 12 146 Funding Number: PA 12 146 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanisms of Alcohol associated Cancers (R21) Apply for PA 12 147 Funding Number: PA 12 147 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Senior Scientist Research Award (K05) Apply for PA 12 048 Funding Number: PA 12 048 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| A Data Resource for Analyzing Blood and Marrow Transplants (Limited Competition U24) Apply for RFA CA 12 503 Funding Number: RFA CA 12 503 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Cancer Target Discovery and Development (CTDD) Network (U01) Apply for RFA CA 12 006 Funding Number: RFA CA 12 006 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| U.S. China Program for Biomedical Collaborative Research (R01) Apply for RFA AI 12 021 Funding Number: RFA AI 12 021 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| NLM Administrative Supplements for Informationist Services in NIH funded Research Projects (Admin Supp) Apply for PA 12 158 Funding Number: PA 12 158 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Senior Scientist Research Award (K05) Apply for PA 12 148 Funding Number: PA 12 148 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Basic Research on HIV Persistence (R21) Apply for PA 12 162 Funding Number: PA 12 162 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Basic Research on HIV Persistence (R01) Apply for PA 12 161 Funding Number: PA 12 161 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Clinical Sequencing Exploratory Research (U01) Apply for RFA HG 12 009 Funding Number: RFA HG 12 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,500,000 |
| Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prevention Trials (R34) Apply for PA 12 171 Funding Number: PA 12 171 Agency: National Institutes of Health Category: Education Health Funding Amount: $225,000 |
| Pre Application for the FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) Apply for PAR 12 164 Funding Number: PAR 12 164 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1) Apply for RFA DA 13 002 Funding Number: RFA DA 13 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Identifying Health Outcomes Associated with Changes in Use of Illicit Drugs (R01) Apply for RFA DA 13 007 Funding Number: RFA DA 13 007 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Synthesis and Preclinical Evaluation of Medications to Treat Substance Use Disorders (SUDs) (R01) Apply for RFA DA 13 004 Funding Number: RFA DA 13 004 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Innovative Health Information Technology for Broad Adoption by Healthcare Systems and Consumers (SBIR) (R44) Apply for PA 12 196 Funding Number: PA 12 196 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Community Clinical Oncology Program Groups (U10) Apply for RFA CA 12 007 Funding Number: RFA CA 12 007 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Minority Based Community Clinical Oncology Program Groups (U10) Apply for RFA CA 12 008 Funding Number: RFA CA 12 008 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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