Opportunity Information: Apply for PAR 10 207
Apply for PAR 10 207
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NEI Clinical Vision Research (U10)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.867 Vision Research.
- This funding opportunity was created on Jun 7, 2013 and posted on May 26, 2010.
- Applicants must submit their applications by Jan 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The NEI Clinical Vision Research (U10) funding opportunity (PAR 10-207) is a National Institutes of Health program run through the National Eye Institute to support investigator-initiated clinical research focused on vision. Its main goal is to provide a clear framework for applicants who want to conduct human clinical vision studies, including clinical trials as well as large-scale epidemiologic studies. In practice, this means NEI is looking to fund well-designed patient-oriented research that can answer meaningful questions about eye disease, visual function, prevention strategies, treatment effectiveness, and real-world outcomes in populations.
This opportunity uses the NIH cooperative agreement mechanism known as U10. A cooperative agreement differs from a standard research grant because it is intended for projects where the NIH expects to have substantial scientific or programmatic involvement during the life of the award. While the research team still leads and carries out the study, the U10 structure typically signals active collaboration with NEI around issues such as study oversight, protocol development or refinement, milestone tracking, performance monitoring, and other elements that are common in complex clinical trials and multi-site or large-cohort epidemiology efforts. For applicants, the key takeaway is that this is designed for clinical vision research that benefits from, or requires, close coordination with the funding institute.
Funding levels and the number of awards are not set to a single fixed amount because the announcement anticipates wide variation in scope. Clinical trials and large epidemiologic studies can differ dramatically in cost, timeline, number of sites, recruitment demands, and data management requirements. As a result, NEI indicates that both award size and duration will vary by application, and the final totals will depend on the number of meritorious applications received, their scientific quality, their proposed timelines, and their budgets. There is no cost sharing or matching requirement, which lowers barriers for institutions that may not have substantial non-federal resources to contribute.
The opportunity is categorized as discretionary funding and sits within the health funding activity area, tied to CFDA 93.867 (Vision Research). A broad range of organizations are eligible to apply. This includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and other nonprofits that do not hold 501(c)(3) status), for-profit organizations (including small businesses and other for-profit entities), and other eligible applicants as described in the full announcement. The eligibility list also explicitly includes several institution types that NIH often highlights to encourage broad participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and non-U.S. entities (foreign organizations). In other words, NEI structured this announcement to be widely accessible across academic, nonprofit, and industry settings, including international partners, as long as the proposed work fits the clinical vision research mission.
Key administrative details in the public listing include a posted date of May 26, 2010, with later record dates reflecting system updates. The original closing date is shown as September 7, 2013, with a current closing date listed as January 7, 2014, and an archive date of February 7, 2014, indicating this specific announcement is no longer active. The full archived announcement was hosted on the NIH grants guide site (PAR-10-207), and the general contact listed for access or linking issues is the NIH Office of Extramural Research webmaster (FBOWebmaster@OD.NIH.GOV).
FAQs: NEI Clinical Vision Research (U10) - PAR-10-207
What is the NEI Clinical Vision Research (U10) opportunity (PAR-10-207)?
PAR-10-207 is a National Institutes of Health (NIH) funding opportunity run through the National Eye Institute (NEI) to support investigator-initiated clinical research focused on vision. It is designed to provide a framework for applicants proposing human clinical vision studies, including clinical trials and large-scale epidemiologic studies.
What types of studies does this opportunity support?
It supports human clinical vision studies, including clinical trials and large-scale epidemiologic studies. The focus is on patient-oriented research intended to answer meaningful questions about eye disease, visual function, prevention strategies, treatment effectiveness, and real-world outcomes in populations.
What is the main goal of this program?
The main goal is to support well-designed clinical vision research and to provide a clear framework for applicants conducting human studies. NEI is aiming to fund projects that can generate actionable evidence related to vision and eye health.
What funding mechanism is used?
This opportunity uses the NIH cooperative agreement mechanism known as U10.
How is a U10 cooperative agreement different from a standard research grant?
A cooperative agreement is intended for projects where NIH expects substantial scientific or programmatic involvement during the award. While the research team leads and carries out the study, the U10 structure typically indicates active collaboration with NEI during the project, such as around study oversight, protocol development or refinement, milestone tracking, and performance monitoring.
What does "substantial NIH involvement" generally mean for applicants?
Based on the description provided, it means the project is expected to involve close coordination with NEI on elements common in complex clinical trials and large epidemiologic efforts, including oversight, protocol-related input, milestone and performance monitoring, and similar programmatic activities.
Is this opportunity intended for multi-site or large-cohort studies?
Yes. The description highlights that the U10 structure is commonly used for complex clinical trials and multi-site or large-cohort epidemiology efforts, where coordination and oversight are significant components of the work.
Is the funding amount fixed?
No. Funding levels are not set to a single fixed amount because the announcement anticipates wide variation in study scope and cost, especially across clinical trials and large epidemiologic studies.
Does the award duration have a fixed limit?
The duration is not fixed to one standard period. NEI indicates that award size and duration will vary by application depending on proposed scope, timelines, and budgets, among other factors.
What factors influence the final award sizes and totals?
Final totals depend on the number of meritorious applications received, scientific quality, proposed timelines, and proposed budgets, reflecting the wide variation in clinical study design and operational needs.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement listed for this opportunity.
What funding category and activity area is this opportunity associated with?
It is categorized as discretionary funding within the health funding activity area. It is tied to CFDA 93.867 (Vision Research).
What organizations are eligible to apply?
A broad range of organizations are eligible, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and other nonprofits), and for-profit organizations (including small businesses and other for-profit entities), as well as other eligible applicants described in the full announcement.
Are minority-serving institutions explicitly included in the eligibility list?
Yes. The eligibility list explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Can non-U.S. (foreign) organizations apply?
Yes. The eligibility list explicitly includes non-U.S. entities (foreign organizations).
Is this opportunity limited to academic institutions?
No. The eligibility description indicates it is widely accessible across academic, nonprofit, and industry settings (including for-profit entities), as well as international partners, as long as the proposed work fits the clinical vision research mission.
Is this funding opportunity still active?
No. The listing indicates the announcement is no longer active. It shows an archive date of February 7, 2014.
What are the key dates listed for this opportunity?
The posted date is May 26, 2010. The original closing date is shown as September 7, 2013, with a current closing date listed as January 7, 2014. The archive date is February 7, 2014.
Where was the full announcement hosted?
The full archived announcement was hosted on the NIH grants guide site under PAR-10-207.
Who is listed as the contact for access or linking issues?
The general contact listed for access or linking issues is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
What is the key takeaway for applicants considering this mechanism?
This mechanism is designed for clinical vision research that benefits from, or requires, close coordination with NEI, particularly for complex clinical trials or large-scale epidemiologic studies where oversight and milestone-driven management are important.
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