Opportunity Information: Apply for PA 07 266
Apply for PA 07 266
- The National Institutes of Health in the education environment health sector is offering a public funding opportunity titled "Networks and Pathways Collaborative Research Projects (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.389 National Center for Research Resources 93.394 Cancer Detection and Diagnosis Research 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.859 Biomedical Research and Research Training 93.866 Aging Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Dec 22, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply.
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Opportunity Summary:
Networks and Pathways Collaborative Research Projects (R01) is an NIH discretionary grant opportunity (Funding Opportunity Number PA 07 266) designed to fund collaborative research that directly connects with the work of the National Technology Centers for Networks and Pathways (TCNPs), which are part of the NIH Roadmap for Medical Research. The central idea is to accelerate biological discovery by pairing innovative, network-and-pathway-focused technologies being developed in the TCNP program with outside research teams that can either apply those tools to important biological questions or build additional tools that make the TCNP technologies more powerful, usable, or broadly applicable.
The program encourages projects in two main directions. One option is to propose a research project that tackles a difficult biological problem using technologies emerging from one or more TCNPs. In practice, this means applicants are expected to identify a compelling biological challenge and show how a TCNP-developed approach (for example, methods for mapping, measuring, modeling, or perturbing molecular networks and pathways) will be leveraged to produce insights that would be hard to obtain otherwise. The second option is more technology-forward: applicants may propose the development of new or improved technology that complements what a TCNP is already building. In this pathway, the expectation is that the work fills a clear gap, extends capability, or removes barriers to adoption so that TCNP technologies can have greater scientific impact.
This opportunity uses the NIH Research Project Grant (R01) mechanism, meaning it supports hypothesis-driven or technology-enabling research projects that can vary widely in scope. A distinctive feature here is the built-in emphasis on collaboration with the TCNPs. Applicants may request funding not only for the work performed by the applicant team, but also supplemental support for components of the project that would be carried out within a participating TCNP. In other words, the grant can be structured so that part of the funded effort happens in close coordination with a TCNP center, aligning deliverables, data generation, or tool development across groups.
Funding levels, project size, project duration, and the anticipated number of awards are not fixed. NIH indicates that awards will depend on the availability of funds and the number of high-quality (meritorious) applications received. Because proposed projects may range from focused applications of an existing platform to substantial complementary technology development, budgets and timelines are expected to differ from one award to the next, and total program output will be driven by application quality, requested costs, and proposed duration.
Eligibility is broad and includes many organization types that commonly apply to NIH research grants. Eligible applicants include public/state-controlled and private institutions of higher education, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in that specific listing), small businesses, for-profit organizations other than small businesses, state governments, U.S. territories or possessions, and other eligible entities listed in the announcement. The FOA explicitly states that non-U.S. (foreign) organizations are eligible to apply, and eligible agencies of the U.S. federal government may also apply. The eligible institution list also calls out Historically Black Colleges and Universities (HBCUs) and Tribally Controlled Colleges and Universities (TCCUs), signaling that these institutions are explicitly included among eligible applicants.
Administratively, the opportunity is issued by the National Institutes of Health and is associated with multiple NIH program areas (as reflected in the CFDA numbers tied to environmental health, mental health, drug abuse, cancer detection and diagnosis, blood diseases, diabetes/digestive/kidney research, neuroscience, general biomedical research and training, and aging research, among others). There is no cost sharing or matching requirement, which is consistent with standard NIH R01 practice. The FOA originally posted on December 22, 2006, used multiple receipt dates (rather than a single deadline), and the announcement later became archived (archive date October 2, 2009), meaning it was time-limited and is no longer active in its original form, though it remains a useful example of NIH efforts to link center-based technology development with investigator-initiated collaborative projects.
For applicants looking to understand the official requirements and any specifics on how to align with TCNP activities, NIH provided a full announcement link and general support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Frequently Asked Questions (FAQs): Networks and Pathways Collaborative Research Projects (R01) - NIH (PA-07-266)
What is the Networks and Pathways Collaborative Research Projects (R01) opportunity?
It is an NIH discretionary funding opportunity (Funding Opportunity Number PA 07 266) using the NIH Research Project Grant (R01) mechanism. It was designed to support collaborative research projects that directly connect with the National Technology Centers for Networks and Pathways (TCNPs), which were part of the NIH Roadmap for Medical Research.
What is the main purpose of this program?
The central goal is to accelerate biological discovery by pairing innovative network- and pathway-focused technologies being developed by TCNPs with outside research teams. Projects are expected to either apply TCNP tools to important biological questions or develop complementary tools that make TCNP technologies more powerful, usable, or broadly applicable.
What are the National Technology Centers for Networks and Pathways (TCNPs)?
TCNPs are NIH Roadmap-associated technology centers focused on developing methods and tools for studying molecular networks and pathways, including approaches for mapping, measuring, modeling, and perturbing biological networks and pathways.
What kinds of projects does the FOA encourage?
The FOA highlights two main project directions: (1) applying TCNP-developed technologies to tackle a difficult biological problem, and (2) developing new or improved technology that complements what a TCNP is already building.
What does it mean to apply TCNP technologies to a biological problem?
Applicants are expected to identify a compelling biological challenge and show how a TCNP-developed approach (such as tools for mapping, measuring, modeling, or perturbing molecular networks and pathways) will be leveraged to generate insights that would be difficult to obtain without those technologies.
What does it mean to develop complementary technology for a TCNP?
This option is for projects that are more technology-forward, where the applicant proposes new or improved technology that fills a gap, extends capability, or removes barriers to adoption so TCNP-developed technologies can have greater scientific impact.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH Research Project Grant (R01) mechanism, which can support hypothesis-driven research and technology-enabling research across a wide range of scopes.
How important is collaboration with a TCNP for this FOA?
Collaboration is a distinctive emphasis of this program. Projects are intended to directly connect with the work of one or more TCNPs, aligning efforts such as deliverables, data generation, and/or tool development across the applicant team and the TCNP center(s).
Can part of the project work be done within a TCNP?
Yes. Applicants may request funding for work performed by the applicant team and may also request supplemental support for components of the project carried out within a participating TCNP.
Does the FOA specify fixed funding levels, award sizes, or project durations?
No. Funding levels, project size, project duration, and the anticipated number of awards are not fixed. NIH indicates awards depend on the availability of funds and the number of meritorious applications received.
Why are budgets and timelines expected to vary across awards?
The FOA anticipates a wide range of project types, from focused applications of existing TCNP platforms to substantial complementary technology development. Because scope can differ significantly, budgets and timelines are expected to vary from one award to the next.
What determines how many awards NIH will make?
The number of awards is expected to depend on available funds and the number of high-quality (meritorious) applications received.
Is there a cost sharing or matching requirement?
No. The FOA states there is no cost sharing or matching requirement, consistent with standard NIH R01 practice.
Who is eligible to apply?
Eligibility is broad and includes many organization types that commonly apply to NIH research grants, including public/state-controlled and private institutions of higher education, nonprofits with or without 501(c)(3) status (as listed in the announcement), small businesses, for-profit organizations other than small businesses, state governments, U.S. territories or possessions, and other eligible entities listed in the FOA.
Are non-U.S. (foreign) organizations eligible?
Yes. The FOA explicitly states that non-U.S. (foreign) organizations are eligible to apply.
Can U.S. federal government agencies apply?
Yes. Eligible agencies of the U.S. federal government may apply, as stated in the eligibility information provided.
Are HBCUs and Tribally Controlled Colleges and Universities included as eligible applicants?
Yes. The eligible institution list specifically calls out Historically Black Colleges and Universities (HBCUs) and Tribally Controlled Colleges and Universities (TCCUs), indicating they are explicitly included among eligible applicants.
Which NIH office issued this funding opportunity?
The opportunity was issued by the National Institutes of Health (NIH).
Is this FOA connected to particular NIH research areas?
Yes. The FOA is associated with multiple NIH program areas, reflected in CFDA numbers tied to areas including environmental health, mental health, drug abuse, cancer detection and diagnosis, blood diseases, diabetes/digestive/kidney research, neuroscience, general biomedical research and training, and aging research, among others.
When was the FOA posted, and is it still active?
The FOA was originally posted on December 22, 2006, used multiple receipt dates, and later became archived (archive date October 2, 2009). As archived, it is no longer active in its original form.
What does it mean that the FOA is archived?
It means the announcement was time-limited and is no longer active for new applications under its original terms, though it remains available as a reference example of NIH efforts to link center-based technology development with investigator-initiated collaborative projects.
Did the FOA have one deadline or multiple receipt dates?
It used multiple receipt dates rather than a single deadline.
Where can applicants find the official announcement and get help with access or linking issues?
NIH provided a full announcement link and general support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 07 266) also looked into and applied for these:
| Funding Opportunity |
|---|
| The Role of Nuclear Receptors in Tissue and Organismal Aging (R01) Apply for PAS 07 267 Funding Number: PAS 07 267 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Global Research Initiative Program, Behavioral/Social Sciences (R01) Apply for PAR 07 328 Funding Number: PAR 07 328 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $50,000 |
| Innovations in Biomedical Computational Science and Technology (R01) Apply for PAR 07 344 Funding Number: PAR 07 344 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Psychopharmacology of Widely Available Psychoactive Natural Products (R01) Apply for PA 07 374 Funding Number: PA 07 374 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Psychopharmacology Of Widely Available Psychoactive Natural Products (R03) Apply for PA 07 375 Funding Number: PA 07 375 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Predictive Multiscale Models of the Physiome in Health and Disease (R01) Apply for PAR 08 023 Funding Number: PAR 08 023 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Nanoscience and Nanotechnology in Biology and Medicine (R01) Apply for PA 08 052 Funding Number: PA 08 052 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Nanoscience and Nanotechnology in Biology and Medicine (R21) Apply for PA 08 053 Funding Number: PA 08 053 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
| In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R21) Apply for PA 08 141 Funding Number: PA 08 141 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01) Apply for PA 08 140 Funding Number: PA 08 140 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Exploratory Collaborations with National Centers for Biomedical Computing (R21) Apply for PAR 08 183 Funding Number: PAR 08 183 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
| Collaborations with National Centers for Biomedical Computing (R01) Apply for PAR 08 184 Funding Number: PAR 08 184 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Metals in Medicine (R01) Apply for PA 08 251 Funding Number: PA 08 251 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Mechanism for Time Sensitive Research Opportunities (R21) Apply for PAR 07 345 Funding Number: PAR 07 345 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Innovations in Biomedical Computational Science and Technology Initiative (SBIR R43/R44) Apply for PAR 07 160 Funding Number: PAR 07 160 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42) Apply for PAR 07 161 Funding Number: PAR 07 161 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Global Research Initiative Program, Basic/Biomedical Sciences (R01) Apply for PAR 07 239 Funding Number: PAR 07 239 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Innovations in Biomedical Computational Science and Technology (R01) Apply for PAR 09 218 Funding Number: PAR 09 218 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Exploratory Innovations in Biomedical Computational Science and Technology (R21) Apply for PAR 09 219 Funding Number: PAR 09 219 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
| Superfund Hazardous Substance Research and Training Program (P42) Apply for RFA ES 09 012 Funding Number: RFA ES 09 012 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
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