Opportunity Information: Apply for PA 10 117
Apply for PA 10 117
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research.
- This funding opportunity was created on Mar 3, 2010 and posted on Mar 3, 2010.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The NIH funding opportunity titled "New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44)" (Funding Opportunity Number PA 10-117) is a discretionary grant program aimed specifically at small business concerns that are building innovations to improve how cardiac arrhythmias are identified and managed. The core goal is to push forward practical, product-oriented research that strengthens our ability to detect, prevent, and treat all forms of heart rhythm disorders. In plain terms, NIH is looking for small companies with credible ideas and development plans for better ways to monitor heart rhythm, spot arrhythmias earlier or more accurately, and deliver more effective treatments, including device-based or technology-enabled approaches that can move toward real-world clinical use.
This FOA uses the Small Business Innovation Research (SBIR) mechanisms R43/R44, meaning it supports the standard SBIR pipeline: Phase I for early-stage proof of concept and feasibility work, Phase II for more advanced research and development toward a deployable product, and a Fast-Track option that can combine Phase I and Phase II in a single, streamlined application path when the project is ready for that. The announcement also notes it runs in parallel with a separate but scientifically identical opportunity (PA 10-118) that uses the Small Business Technology Transfer (STTR) mechanisms (R41/R42). That parallel listing matters mainly for applicants deciding whether their project fits better under SBIR (small business-led R&D) or STTR (formal collaboration with a nonprofit research institution), even though the research topics NIH wants to fund are essentially the same in both.
The program sits within NIH's cardiovascular research area (CFDA 93.837, Cardiovascular Diseases Research) and does not require cost sharing or matching funds, which reduces the financial burden on applicants. Eligibility is limited to small businesses, consistent with SBIR rules, and the opportunity is structured to support development of diagnostic and therapeutic tools, products, or devices. While the announcement does not lock applicants into a narrow technical approach, the intent is clearly translational: projects should be oriented toward solutions that can realistically improve arrhythmia monitoring, detection, and treatment, not just generate basic scientific knowledge without a pathway to a usable technology.
On funding, NIH emphasizes that awards depend on the availability of funds and the strength of the submitted proposals, so there is no guaranteed number of awards. The total dollars and the number of projects funded will vary based on application quality, project duration, and requested budgets. The listing shows an award ceiling of $200,000 (commonly aligned with Phase I budget expectations in many SBIR contexts), but actual award amounts in practice typically depend on the phase, the justification provided, and NIH policy at the time of award. The opportunity was posted March 3, 2010, with an original and current closing date of January 7, 2013, and it was archived February 7, 2013, meaning it is no longer open for new submissions under that specific announcement number and timeframe, though similar topics may reappear in newer NIH SBIR solicitations.
For access and administrative help, the announcement directs applicants to the NIH Office of Extramural Research (OER) Webmaster for technical issues viewing the full posting or problems with the link to the announcement. The official details were hosted at the NIH grants guide page referenced in the Additional Information link.
FAQs: New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44) - NIH (PA 10-117)
What is the NIH funding opportunity PA 10-117 about?
PA 10-117 is an NIH Small Business Innovation Research (SBIR) funding opportunity titled "New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44)." It is intended to support small businesses developing practical, product-oriented innovations that improve how cardiac arrhythmias are identified and managed, including better monitoring, earlier or more accurate detection, and more effective treatments.
What types of projects is NIH looking to fund under this program?
Based on the announcement description, NIH is looking for translational projects aimed at real-world use. That includes diagnostic and therapeutic tools, products, devices, or technology-enabled approaches that can realistically improve arrhythmia monitoring, detection, prevention, and treatment, rather than basic research with no clear pathway to a usable technology.
Who is eligible to apply?
Eligibility is limited to small business concerns, consistent with SBIR rules. The opportunity is specifically aimed at small companies developing innovations related to arrhythmia detection and treatment.
Is this an SBIR or STTR opportunity?
This specific announcement (PA 10-117) uses the SBIR mechanisms R43/R44. The notice also states it runs in parallel with a separate, scientifically identical listing (PA 10-118) that uses STTR mechanisms (R41/R42). Applicants would choose SBIR versus STTR based on which program structure best matches how the work will be led and organized.
What do the SBIR mechanisms R43 and R44 mean?
R43 and R44 refer to the standard SBIR phases supported by NIH. Phase I (R43) typically supports early-stage proof of concept and feasibility work. Phase II (R44) supports more advanced research and development intended to move the technology closer to a deployable product.
Is there a Fast-Track option?
Yes. The announcement notes a Fast-Track option, which can combine Phase I and Phase II into a single, streamlined application path when a project is ready for that structure.
What is the main goal of this FOA?
The core goal is to advance practical, product-oriented research that strengthens the ability to detect, prevent, and treat all forms of heart rhythm disorders. In plain terms, NIH is seeking credible development plans for better arrhythmia monitoring and treatment approaches that can move toward clinical use.
Does the FOA restrict applicants to a specific technology approach?
No specific narrow technical approach is required based on the description provided. However, the intent is clearly translational: proposed work should be oriented toward solutions that can realistically improve monitoring, detection, and treatment of arrhythmias.
What program area or CFDA listing does this fall under?
The program is within NIH's cardiovascular research area and is listed under CFDA 93.837 (Cardiovascular Diseases Research).
Is cost sharing or matching required?
No. The opportunity states that it does not require cost sharing or matching funds.
How much funding is available per award?
The listing shows an award ceiling of $200,000, commonly aligned with Phase I budget expectations in many SBIR contexts. Actual award amounts can depend on the SBIR phase, the budget justification, project duration, proposal strength, and NIH policies at the time of award.
Is the number of awards guaranteed?
No. NIH indicates that awards depend on the availability of funds and the strength of submitted proposals. The number of projects funded and total dollars awarded can vary based on application quality, project duration, and requested budgets.
When was this opportunity posted, and when did it close?
The opportunity was posted on March 3, 2010. The original and current closing date listed is January 7, 2013.
Is PA 10-117 still open for new applications?
No. The opportunity was archived on February 7, 2013, which means it is no longer open for new submissions under that specific announcement number and timeframe.
If it is archived, is there any way to pursue similar NIH funding for this topic?
The notice indicates that similar topics may reappear in newer NIH SBIR solicitations. The archived status only applies to PA 10-117 as listed; it does not rule out that NIH may offer related opportunities under different, more current announcements.
Where were the official details hosted?
The official details were hosted on the NIH Grants Guide page referenced by the "Additional Information" link in the announcement.
Who should be contacted for technical issues accessing the announcement?
For technical issues viewing the full posting or problems with the link to the announcement, applicants were directed to the NIH Office of Extramural Research (OER) Webmaster.
Browse more opportunities from the same category: Health
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