Opportunity Information: Apply for PA 10 118
Apply for PA 10 118
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "New Approaches to Arrhythmia Detection and Treatment (STTR R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research.
- This funding opportunity was created on Mar 3, 2010 and posted on Mar 3, 2010.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The New Approaches to Arrhythmia Detection and Treatment (STTR R41/R42) opportunity (Funding Opportunity Number PA-10-118) is a National Institutes of Health (NIH) discretionary grant program designed to push forward better ways to identify, monitor, prevent, and treat cardiac arrhythmias. The core idea is to support small businesses that are developing practical, innovative technologies that can improve real-world arrhythmia care, whether that means finding rhythm problems earlier, measuring them more accurately over time, predicting dangerous events, or delivering more effective treatments. The focus is broad across "all forms" of cardiac arrhythmias, so proposals are not limited to one specific condition and can span everything from intermittent rhythm disorders that are hard to capture to more persistent or life-threatening arrhythmias where better therapy or monitoring could significantly improve outcomes.
This announcement uses the Small Business Technology Transfer (STTR) mechanism, specifically the R41 and R42 grant types. In plain terms, that means it is aimed at small business concerns (SBCs) that will work in formal collaboration with a nonprofit research institution (a typical STTR requirement), combining commercial development capability with research expertise. The FOA supports Phase I projects (R41), which are generally meant to establish feasibility and demonstrate proof of concept, and Phase II projects (R42), which are meant to continue development, validation, and progress toward commercialization and broader adoption. It also allows Fast Track applications, which are intended for teams that are ready to propose an integrated Phase I/Phase II plan and want to move from feasibility to development on an accelerated path.
From a project content standpoint, NIH is explicitly encouraging the creation or improvement of diagnostic and therapeutic tools, products, and devices related to arrhythmia monitoring, detection, and treatment. That can reasonably include new sensing approaches (wearable, implantable, or bedside), improved signal processing or interpretation methods, smarter alerting and triage systems, novel ways to capture rare or episodic arrhythmias, and technology that helps clinicians tailor therapy. On the treatment side, it can include innovations that improve how therapies are delivered or controlled, or that reduce complications and improve patient quality of life. The framing is strongly translational: the agency is looking for advances that can become usable products, not just basic science findings.
Administratively, the program is listed under CFDA 93.837 (Cardiovascular Diseases Research). There is no cost sharing or matching requirement, which means applicants are not required to provide matching funds as a condition of the award. Eligibility is limited to small businesses. The award ceiling listed for the opportunity is $200,000, and the number and total dollar amount of awards are not guaranteed; awards depend on available funds and on whether NIH receives enough high-quality, competitive applications. In other words, the program is competitive and budget outcomes depend on merit, project duration, and the proposed costs.
This STTR FOA runs in parallel with a separate NIH announcement of the same scientific scope for the SBIR program (PA-10-117), which uses the R43/R44 mechanisms. The practical implication is that small companies should pay attention to which mechanism fits their situation best: STTR is built around a required small business and research institution partnership, while SBIR has different collaboration rules. The science goals are essentially the same, but the business/research relationship structure differs.
In terms of timing and status, the opportunity was posted and created on March 3, 2010, with an original and current closing date of January 7, 2013, and an archive date of February 7, 2013. That means the specific announcement is no longer active, but it remains useful as a reference for the types of arrhythmia technology projects NIH was seeking to fund under STTR at that time, and it may mirror the structure and priorities of later or successor NIH solicitations in the cardiovascular devices and diagnostics space.
For applicants needing official details or having technical trouble accessing the full text, the source points to the NIH grants page for PA-10-118 and lists the NIH Office of Extramural Research (OER) webmaster contacts (FBOWebmaster@OD.NIH.GOV) for access or linking issues.
Frequently Asked Questions (FAQs)
What is the funding opportunity called and what is its purpose?
The opportunity is titled "New Approaches to Arrhythmia Detection and Treatment (STTR R41/R42)" (Funding Opportunity Number PA-10-118). It is an NIH discretionary grant program intended to advance better ways to identify, monitor, prevent, and treat cardiac arrhythmias by supporting practical, innovative technologies that can improve real-world arrhythmia care.
Which federal agency is offering this opportunity?
This opportunity is offered by the National Institutes of Health (NIH).
What types of health conditions and use cases are in scope?
The focus is broad across "all forms" of cardiac arrhythmias. Projects can address intermittent rhythm disorders that are difficult to capture, more persistent arrhythmias, or life-threatening arrhythmias where improved monitoring or therapy could significantly improve outcomes.
What does NIH want applicants to build or improve?
NIH is encouraging the creation or improvement of diagnostic and therapeutic tools, products, and devices related to arrhythmia monitoring, detection, and treatment, with an emphasis on translational work that can become usable products.
What kinds of diagnostic technologies fit the goals described?
Examples consistent with the announcement include new sensing approaches (wearable, implantable, or bedside), improved signal processing or interpretation methods, smarter alerting and triage systems, and novel ways to capture rare or episodic arrhythmias.
What kinds of treatment technologies fit the goals described?
On the treatment side, the scope includes innovations that improve how therapies are delivered or controlled, reduce complications, improve patient quality of life, and help clinicians tailor therapy.
What funding mechanism does this announcement use?
This announcement uses the Small Business Technology Transfer (STTR) mechanism, specifically the R41 and R42 grant types.
Who is eligible to apply?
Eligibility is limited to small businesses (small business concerns, or SBCs).
Is a research institution partnership required under this STTR opportunity?
Yes. The STTR mechanism is described as requiring a formal collaboration between the small business and a nonprofit research institution, combining commercial development capability with research expertise.
What is the difference between Phase I (R41) and Phase II (R42) in this program?
Phase I (R41) projects are generally meant to establish feasibility and demonstrate proof of concept. Phase II (R42) projects are intended to continue development, validation, and progress toward commercialization and broader adoption.
Does the program allow a Fast Track application?
Yes. The opportunity allows Fast Track applications for teams ready to propose an integrated Phase I/Phase II plan and move from feasibility to development on an accelerated path.
Is this opportunity more focused on basic science or product development?
The framing is strongly translational. NIH is looking for advances that can become usable products, not just basic science findings.
What is the CFDA number associated with this program?
The program is listed under CFDA 93.837 (Cardiovascular Diseases Research).
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to provide matching funds as a condition of the award.
What is the award ceiling listed for this opportunity?
The award ceiling listed is $200,000.
Are awards guaranteed and how many awards will be made?
No. The number and total dollar amount of awards are not guaranteed. Awards depend on available funds and whether NIH receives enough high-quality, competitive applications.
How competitive is this program described to be?
It is described as competitive, with budget outcomes depending on merit, project duration, and proposed costs, as well as the availability of funds.
Is there a related SBIR opportunity, and how does it differ?
Yes. A parallel NIH announcement with the same scientific scope is referenced for the SBIR program (PA-10-117), using the R43/R44 mechanisms. The practical difference highlighted is that STTR requires a small business and research institution partnership, while SBIR has different collaboration rules, even though the science goals are essentially the same.
When was this FOA posted and what is its current status?
It was posted and created on March 3, 2010. The original and current closing date listed is January 7, 2013, and the archive date is February 7, 2013. That indicates the specific announcement is no longer active.
If the announcement is archived, why might it still be useful?
It may still be useful as a reference for the types of arrhythmia technology projects NIH was seeking to fund under STTR at that time, and it may mirror the structure and priorities of later or successor NIH solicitations in cardiovascular devices and diagnostics.
Where can applicants find the official source for PA-10-118?
The information points to the NIH grants page for PA-10-118 as the official source.
Who should be contacted for technical trouble accessing the full text or for linking issues?
The NIH Office of Extramural Research (OER) webmaster contact is listed for access or linking issues: FBOWebmaster@OD.NIH.GOV.
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Previous opportunity: New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44)
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