Opportunity Information: Apply for PA 12 090

  • The National Institutes of Health in the education food and nutrition health income security and social services sector is offering a public funding opportunity titled "New Technologies for Viral Hepatitis SBIR (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Dec 18, 2014 and posted on Jan 31, 2012.
  • Applicants must submit their applications by Dec 19, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
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Opportunity Summary:

The New Technologies for Viral Hepatitis SBIR (R43/R44) opportunity (Funding Opportunity Number PA 12 090) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant program designed to push forward practical, high-impact innovations that address viral hepatitis in the United States. The central aim is to stimulate research and development by small business concerns that directly supports the U.S. Department of Health and Human Services initiative known as the Viral Hepatitis Action Plan, formally titled Combating the Silent Epidemic of Viral Hepatitis: Action Plan for the Prevention, Care and Treatment of Viral Hepatitis (released May 12, 2011). In other words, the government is using SBIR funding to help small companies translate scientific and technical ideas into real-world tools that improve how viral hepatitis is prevented, detected, tracked, and treated, as well as how hepatitis-related liver disease is managed.

This FOA invites small businesses to propose projects that create or significantly advance resources and technologies for viral hepatitis and associated liver disease. The scope is broad and intentionally flexible, covering everything from research tools and instrumentation to biomarkers, diagnostics, devices, and therapeutics, along with new approaches to clinical management and prevention. Applicants are encouraged to focus on innovation that meaningfully improves diagnosis (for example, earlier detection or more accurate differentiation of infections), monitoring (such as tracking disease progression or treatment response), management (tools that support clinical decisions or patient engagement), treatment (including drug development or improved therapeutic strategies), and prevention (which could include novel screening approaches or technologies that reduce transmission). The emphasis is on developing tangible technologies or approaches that can be validated and ultimately adopted in research, clinical, or public health settings.

The funding mechanism is SBIR, using the R43/R44 activity codes, which are commonly associated with the SBIR phased structure. In practice, this typically supports early-stage feasibility and proof-of-concept work and can extend into more advanced development stages aimed at moving a product or technology closer to commercialization and broader deployment. Because this is an SBIR opportunity, eligibility is limited to small business concerns, and the program is structured to support R and D that has a clear pathway toward practical use and market impact, not just academic discovery.

Administratively, the opportunity is categorized as discretionary funding and uses the grant instrument type. It states there is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of the award. The FOA was posted on January 31, 2012, and the listing includes key archival dates indicating the announcement has closed (with an original closing date of January 7, 2015; a current closing date listed as December 19, 2014; and an archive date of January 18, 2015). While those dates mean the specific announcement is historical, the content still provides a clear picture of NIH priorities at that time and the kinds of hepatitis-related innovations NIH sought to stimulate through small business funding.

The opportunity is associated with multiple CFDA program areas spanning infectious disease and broader biomedical domains, reflecting how viral hepatitis intersects with many health fields. The CFDA numbers listed include programs related to alcohol research, cancer cause/prevention/detection/treatment, blood diseases, diabetes/digestive/kidney diseases, allergy and infectious diseases, microbiology, and child health and human development. This mix signals that viral hepatitis is viewed not only as an infectious disease challenge but also as a driver of downstream conditions such as cirrhosis and liver cancer, and as a public health issue affecting diverse populations and healthcare systems.

For applicants and interested parties seeking the full technical requirements and application instructions, the announcement points to the NIH Grants Guide page (Additional Information Link: http://grants.nih.gov/grants/guide/pa-files/PA-12-090.html). The contact provided is the NIH Office of Extramural Research (OER) webmaster support (FBOWebmaster@OD.NIH.GOV) for issues accessing or linking to the announcement.

FAQs: New Technologies for Viral Hepatitis SBIR (R43/R44) - PA 12 090

What is the New Technologies for Viral Hepatitis SBIR (R43/R44) opportunity?

It is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) funding opportunity intended to advance practical, high-impact innovations that address viral hepatitis and related liver disease in the United States.

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA 12 090.

What is the main goal of this SBIR program?

The central goal is to stimulate research and development by small business concerns so scientific and technical ideas can be translated into real-world tools that improve prevention, detection, tracking, and treatment of viral hepatitis, as well as management of hepatitis-related liver disease.

How does this opportunity relate to the Viral Hepatitis Action Plan?

This SBIR opportunity is designed to directly support the U.S. Department of Health and Human Services initiative: Combating the Silent Epidemic of Viral Hepatitis: Action Plan for the Prevention, Care and Treatment of Viral Hepatitis (released May 12, 2011).

Who is eligible to apply?

Eligibility is limited to small business concerns, consistent with SBIR program requirements.

What funding mechanism and activity codes does this opportunity use?

The mechanism is SBIR and it uses NIH activity codes R43/R44, which are commonly associated with the SBIR phased structure.

What kinds of projects are within scope?

The scope is broad and flexible. Small businesses may propose projects that create or significantly advance resources and technologies for viral hepatitis and associated liver disease, including research tools and instrumentation, biomarkers, diagnostics, devices, therapeutics, and new approaches to clinical management and prevention.

What areas of impact does NIH encourage applicants to focus on?

Applicants are encouraged to focus on innovation that meaningfully improves diagnosis, monitoring, management, treatment, and prevention related to viral hepatitis and associated liver disease.

Are there examples of what "improving diagnosis" could mean under this FOA?

The FOA cites examples such as earlier detection or more accurate differentiation of infections.

What does "monitoring" refer to in the context of this opportunity?

Monitoring includes technologies or approaches for tracking disease progression or treatment response.

What does "management" refer to here?

Management includes tools that support clinical decisions or patient engagement for viral hepatitis and related liver disease.

What does "prevention" include in this FOA?

Prevention can include novel screening approaches or technologies that reduce transmission.

Does this SBIR opportunity emphasize basic research or practical technology development?

The emphasis is on developing tangible technologies or approaches that can be validated and ultimately adopted in research, clinical, or public health settings, with a clear pathway toward practical use and market impact.

Is there a commercialization expectation?

Because it is an SBIR opportunity, it is structured to support research and development with a clear pathway toward practical use and market impact, rather than purely academic discovery.

Is cost sharing or matching required?

No. The opportunity explicitly states there is no cost sharing or matching requirement.

What type of funding is this and what award instrument is used?

It is categorized as discretionary funding and uses the grant instrument type.

When was this FOA posted?

The FOA was posted on January 31, 2012.

Is this funding opportunity still open?

No. The listing indicates the announcement has closed and is historical, with archival dates showing an original closing date of January 7, 2015, a current closing date listed as December 19, 2014, and an archive date of January 18, 2015.

If the FOA is closed, why might it still be useful?

Even though the specific announcement is historical, it describes NIH priorities at the time and the types of viral hepatitis innovations NIH sought to stimulate through small business funding.

What CFDA program areas are associated with this opportunity?

The opportunity is associated with multiple CFDA program areas across infectious disease and broader biomedical domains, including alcohol research; cancer cause, prevention, detection, and treatment; blood diseases; diabetes, digestive and kidney diseases; allergy and infectious diseases; microbiology; and child health and human development.

What does the mix of CFDA areas suggest about how NIH views viral hepatitis?

The mix signals that viral hepatitis is treated not only as an infectious disease challenge, but also as a driver of downstream conditions such as cirrhosis and liver cancer, and as a public health issue affecting diverse populations and healthcare systems.

Where can applicants find the full announcement and detailed application instructions?

The FOA points to the NIH Grants Guide page at: http://grants.nih.gov/grants/guide/pa-files/PA-12-090.html

Who is the listed contact for access or linking issues?

The contact provided is the NIH Office of Extramural Research (OER) webmaster support: FBOWebmaster@OD.NIH.GOV

What is the intended outcome of projects supported by this FOA?

The intent is to help small companies move innovations toward real-world validation and adoption in research, clinical, or public health settings, ultimately improving how viral hepatitis is prevented, detected, tracked, treated, and managed.

Browse more business programs for Viral Hepatitis Research

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Previous opportunity: New Technologies for Viral Hepatitis STTR (R41/R42)

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