Opportunity Information: Apply for PA 12 091
Apply for PA 12 091
- The National Institutes of Health in the education food and nutrition health income security and social services sector is offering a public funding opportunity titled "New Technologies for Viral Hepatitis STTR (R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 18, 2014 and posted on Jan 31, 2012.
- Applicants must submit their applications by Dec 19, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The grant opportunity called "New Technologies for Viral Hepatitis STTR (R41/R42)" (Funding Opportunity Number PA-12-091) is a National Institutes of Health (NIH) Small Business Technology Transfer (STTR) program announcement designed to push new, practical technologies and product-like innovations that can reduce the burden of viral hepatitis in the United States. It is framed around the goals of the U.S. Department of Health and Human Services Viral Hepatitis Action Plan released in 2011, which emphasizes stronger prevention, better testing and linkage to care, improved treatment outcomes, and reduced complications such as cirrhosis and liver cancer. In plain terms, NIH is using the STTR mechanism to encourage small businesses to partner with research institutions and move promising hepatitis-related ideas toward real-world tools that clinicians, public health programs, and patients can actually use.
This funding is specifically for eligible small business concerns, reflecting the STTR program's focus on commercialization-oriented research and development. Applicants are encouraged to propose projects that create or substantially improve resources and enabling technologies related to viral hepatitis and hepatitis-associated liver disease. The announcement highlights a wide range of possible innovations, including research tools and laboratory resources, instrumentation, biomarkers, devices, drug candidates, and other novel approaches that improve diagnosis, monitoring, management, treatment, or prevention. The scope is intentionally broad so companies can propose anything from new diagnostic assays that detect infection earlier, to better ways of tracking treatment response, to technologies that help manage chronic infection and its long-term liver consequences.
The FOA uses the STTR phased award structure (R41/R42). While the announcement text provided does not spell out the full phase details, the standard R41/R42 structure generally supports an initial feasibility stage followed by a more advanced development stage, with the expectation that successful projects will be positioned for further development, regulatory steps when relevant, and ultimately commercialization or deployment. That fits the overall intent here: not just basic science, but translational work that produces deliverables such as prototypes, validated biomarkers, candidate therapeutics, or scalable platforms that can be adopted by the healthcare system or public health programs.
Administratively, this is a discretionary grant opportunity under NIH, with no cost sharing or matching requirement. The opportunity is categorized under multiple CFDA program areas spanning infectious diseases and liver-related conditions, including allergy and infectious diseases, microbiology and infectious diseases, diabetes/digestive/kidney diseases, blood diseases, child health and human development, alcohol research, and several cancer research categories. That mix reflects how viral hepatitis intersects with many NIH mission areas, particularly because chronic hepatitis can lead to liver fibrosis, cirrhosis, and hepatocellular carcinoma, and because prevention and treatment strategies often overlap with broader infectious disease control efforts.
Key dates in the source data show it was posted January 31, 2012, with a listed original closing date of January 7, 2015, a current closing date of December 19, 2014, and an archive date of January 18, 2015. In other words, it is an archived opportunity rather than an active one today, but it still serves as a useful reference point for the kinds of hepatitis-focused STTR projects NIH has sought to fund. The full announcement and related instructions were provided through NIH's grants guide webpage (the link in the source points to the detailed FOA text), and NIH's Office of Extramural Research webmaster contact is listed for access or technical issues.
Overall, the opportunity is best understood as NIH's attempt to speed up the pipeline from research to usable technology in the viral hepatitis space by leveraging small business innovation, academic-industry collaboration, and phased development support. Projects most aligned with the FOA are those that clearly address an unmet need in hepatitis prevention or care, demonstrate a plausible technical path to a working product or validated tool, and show awareness of how the innovation could be implemented in clinical or public health settings to reduce infections, improve outcomes, and prevent serious liver disease.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "New Technologies for Viral Hepatitis STTR (R41/R42)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-12-091.
Which federal agency is offering this opportunity?
This is a National Institutes of Health (NIH) funding opportunity offered through the NIH Small Business Technology Transfer (STTR) program.
What is the main purpose of this STTR program announcement?
The purpose is to stimulate new, practical technologies and product-like innovations that can reduce the burden of viral hepatitis in the United States, with an emphasis on moving promising ideas toward real-world tools that can be used by clinicians, public health programs, and patients.
How does this opportunity connect to federal viral hepatitis priorities?
The program is framed around the goals of the U.S. Department of Health and Human Services Viral Hepatitis Action Plan released in 2011, which emphasizes stronger prevention, better testing and linkage to care, improved treatment outcomes, and reduced complications such as cirrhosis and liver cancer.
Who is this funding intended for?
This funding is specifically for eligible small business concerns, consistent with the STTR program's focus on commercialization-oriented research and development and small business collaboration with a research institution.
Does the opportunity emphasize partnerships?
Yes. It uses the STTR mechanism, which is intended to encourage small businesses to partner with research institutions to translate hepatitis-related research into practical, usable technologies.
What kinds of projects does the FOA encourage?
Applicants are encouraged to propose projects that create or substantially improve resources and enabling technologies related to viral hepatitis and hepatitis-associated liver disease, with a focus on translational work that leads to usable deliverables.
What types of technologies are in scope?
The scope is intentionally broad and includes (but is not limited to) research tools and laboratory resources, instrumentation, biomarkers, devices, drug candidates, and other novel approaches that improve diagnosis, monitoring, management, treatment, or prevention of viral hepatitis and related liver disease.
Are diagnostics and testing technologies relevant to this FOA?
Yes. The announcement explicitly highlights innovations such as diagnostic assays that detect infection earlier, as well as technologies that support better testing and linkage to care.
Are monitoring or treatment-response tools relevant?
Yes. The FOA notes interest in better ways of tracking treatment response and technologies that support monitoring and management of infection and hepatitis-associated liver disease.
Are chronic hepatitis management and long-term liver complications part of the focus?
Yes. The opportunity is tied to reducing complications such as cirrhosis and liver cancer and encourages technologies that help manage chronic infection and its long-term liver consequences.
Are therapeutics or drug candidates allowed under this announcement?
Yes. The announcement includes drug candidates among the examples of possible innovations, alongside devices, biomarkers, and other approaches.
What do the R41 and R42 designations mean in this announcement?
This FOA uses the STTR phased award structure (R41/R42). While the provided text does not list full phase details, the standard structure generally includes an initial feasibility stage followed by a more advanced development stage, with the expectation that successful projects are positioned for further development and commercialization or deployment.
Is this opportunity focused on basic science or on translational product development?
The overall intent is translational: supporting work that produces product-like deliverables such as prototypes, validated biomarkers, candidate therapeutics, or scalable platforms that could be adopted by healthcare systems or public health programs.
What kinds of deliverables does NIH appear to be seeking through this FOA?
Based on the description, aligned deliverables include prototypes, validated biomarkers, candidate therapeutics, scalable technology platforms, and other enabling tools that are practical and positioned for real-world use.
Is cost sharing or matching required?
No. The opportunity is described as having no cost sharing or matching requirement.
What type of grant is this described as administratively?
It is described as a discretionary grant opportunity under NIH.
Which program areas (CFDA categories) are associated with this opportunity?
The opportunity is categorized under multiple CFDA program areas spanning infectious diseases and liver-related conditions, including allergy and infectious diseases, microbiology and infectious diseases, diabetes/digestive/kidney diseases, blood diseases, child health and human development, alcohol research, and several cancer research categories.
Why are so many NIH program areas connected to a viral hepatitis technology FOA?
The listing reflects that viral hepatitis intersects with many NIH mission areas. Chronic hepatitis can lead to liver fibrosis, cirrhosis, and hepatocellular carcinoma, and prevention and treatment strategies often overlap with broader infectious disease control efforts.
Is this an active funding opportunity today?
No. The dates provided indicate it is an archived opportunity rather than an active one.
When was this opportunity posted?
The posting date listed is January 31, 2012.
What are the closing and archive dates listed for this FOA?
The source data lists an original closing date of January 7, 2015, a current closing date of December 19, 2014, and an archive date of January 18, 2015.
Where could applicants find the full FOA text and instructions (as referenced)?
The full announcement and related instructions were provided through the NIH Grants Guide webpage referenced by the source link for the detailed FOA text.
Is there a contact listed for access or technical issues related to the announcement?
Yes. NIH's Office of Extramural Research webmaster contact is listed for access or technical issues, according to the information provided.
What kinds of proposals appear most aligned with the intent of this FOA?
Projects most aligned are those that address an unmet need in hepatitis prevention or care, show a plausible technical path to a working product or validated tool, and demonstrate awareness of how the innovation could be implemented in clinical or public health settings to reduce infections, improve outcomes, and prevent serious liver disease.
Browse more opportunities from the same agency: National Institutes of Health
Browse more opportunities from the same category: Education Food and Nutrition Health Income Security and Social Services
Next opportunity: New Technologies for Viral Hepatitis SBIR (R43/R44)
Previous opportunity: PHS 2012 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 12 091) also looked into and applied for these:
| Funding Opportunity |
|---|
| New Technologies for Viral Hepatitis SBIR (R43/R44) Apply for PA 12 090 Funding Number: PA 12 090 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition Revision Applications to Advance Evidence Based Research Related to Protections for Human Subjects (U54) Apply for PAS 12 169 Funding Number: PAS 12 169 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition Revision Applications to Advance Evidence Based Research Related to Protections for Human Subjects (U01) Apply for PAS 12 166 Funding Number: PAS 12 166 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Multidisciplinary Studies of HIV/AIDS and Aging (R01) Apply for PAR 12 175 Funding Number: PAR 12 175 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Exploratory/Developmental Clinical Research Grants in Obesity (R21) Apply for PA 12 179 Funding Number: PA 12 179 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Improving Diet and Physical Activity Assessment (R21) Apply for PAR 12 197 Funding Number: PAR 12 197 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Improving Diet and Physical Activity Assessment (R01) Apply for PAR 12 198 Funding Number: PAR 12 198 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Time Sensitive Obesity Policy and Program Evaluation (R01) Apply for PAR 12 257 Funding Number: PAR 12 257 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Obesity Policy Evaluation Research (R01) Apply for PA 13 110 Funding Number: PA 13 110 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Mechanisms, Models, Measurement, Management in Pain Research (R01) Apply for PA 13 118 Funding Number: PA 13 118 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Development of Assays for High Throughput Screening for Use in Probe and Pre therapeutic Discovery (R01) Apply for PAR 13 364 Funding Number: PAR 13 364 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH/PEPFAR Collaboration for Implementation Science (Admin Supp) Apply for PA 14 024 Funding Number: PA 14 024 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $500,000 |
| Centers for AIDS Research and Developmental Centers for AIDS Research (P30) Apply for PAR 14 041 Funding Number: PAR 14 041 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $750,000 |
| Empirical Research on Ethical Issues Related to Central IRBs and Consent for Research Using Clinical Records and Data (R01) Apply for RFA OD 14 002 Funding Number: RFA OD 14 002 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Chronic Overlapping Pain Conditions (R01) Apply for PA 14 244 Funding Number: PA 14 244 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| High Throughput Screening (HTS) to Discover Chemical Probes (R01) Apply for PAR 14 284 Funding Number: PAR 14 284 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Big Data to Knowledge (BD2K) Enhancing Diversity in Biomedical Data Science (R25) Apply for RFA MD 15 005 Funding Number: RFA MD 15 005 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01) Apply for PA 15 135 Funding Number: PA 15 135 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Exploratory/Developmental Clinical Research Grants in Obesity (R21) Apply for PA 15 163 Funding Number: PA 15 163 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Diet and Physical Activity Assessment Methodology (R01) Apply for PAR 15 170 Funding Number: PAR 15 170 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
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