Opportunity Information: Apply for RFA AR 09 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research.
  • This funding opportunity was created on Oct 8, 2008 and posted on Oct 8, 2008.
  • Applicants must submit their applications by Feb 19, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 10 candidate(s).
  • Eligible applicants include: Independent school districts County governments Native American tribal governments (Federally recognized) Private institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession This FOA is a revision that involves an active NIAMS R01. Only current active NIAMS R01 grantees are eligible to submit applications. Grantees with other equivalent awards are encouraged to apply with NIAMS R01 grantees.
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Opportunity Summary:

The NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards (R01) opportunity (Funding Opportunity Number RFA-AR-09-001) is a National Institutes of Health program run by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Its central goal is to spark new, genuinely interdisciplinary collaborations by providing short-term, competitive revision support to existing, active NIAMS-funded R01 projects. The idea is to help an established R01-funded research effort bring in a new partner (or partners) from a different discipline, so the team can tackle a shared scientific problem in a way that would not be achievable by any of the investigators working on their own. NIAMS makes clear that the collaboration is expected to be innovative, potentially high-impact, and may involve higher risk than more conventional projects, with the expectation that the payoff could be substantial.

This FOA specifically targets interdisciplinary work in NIAMS mission-relevant areas and highlights particular cross-cutting scientific themes that NIAMS selected to pilot the BIRT concept. The solicited areas include autoimmunity, gender and sex factors, systems biology, developmental biology, regenerative medicine, immunology, soft tissue biology, imaging technologies, and tissue engineering. The emphasis is on forming teams that connect complementary strengths across these domains, for example pairing immunology and systems biology approaches to address autoimmune mechanisms, or combining tissue engineering with imaging technologies to better track regenerative processes. The key requirement is that the added collaboration meaningfully expands the scientific scope of the parent R01 by bringing in expertise and methods that are not already present in the funded project.

From a funding and structure standpoint, this is not a new standalone R01. It uses the NIH revision mechanism to an existing R01 (what many investigators previously knew as a competitive supplement). NIAMS planned to provide up to one year of additional support per award, with direct costs capped at $100,000 for the revision. The parent NIAMS R01 must still have enough time remaining to allow the collaboration to be developed and tested; in this announcement NIAMS specified that the parent grant should not end earlier than January 31, 2011. NIAMS anticipated committing about $1 million in direct costs in fiscal year 2009 to support up to 10 total BIRT awards across two parallel announcements: this R01 revision FOA (RFA-AR-09-001) and a companion FOA (RFA-AR-09-002) that uses larger, multi-project or cooperative agreement mechanisms (U01, U54, P01, P50, P60) but has the same scientific scope.

Eligibility is narrowly defined around the parent award. Only investigators who already hold an active NIAMS R01 are eligible to submit an application under this FOA, because the application is a revision to that existing grant. The program is designed to encourage those NIAMS R01 principal investigators to build new collaborations with independent investigators from other disciplines, whether those collaborators are funded by NIAMS, other NIH institutes and centers, or entirely different funding agencies. Multiple PDs/PIs are allowed on the application, which is helpful for true team science proposals where leadership is shared across disciplines. While many institution types are broadly eligible in NIH terms (including universities, nonprofits, small businesses, certain government entities, and even foreign organizations as listed in the announcement), the practical gatekeeper remains the same: the submitting team must be anchored by an active NIAMS R01 that will receive the revision.

NIAMS also sets clear application limits and restrictions to keep the program focused on new team formation rather than extending existing partnerships. An applicant can submit more than one BIRT application as long as each is scientifically distinct, but only one BIRT application may be submitted per active NIAMS R01. Importantly, the revision cannot be used to fund collaborations that are already formal, ongoing components of the parent grant or other funded projects. In other words, NIAMS is paying for a new interdisciplinary partnership to be launched, not to continue something already underway. Resubmissions are not permitted, and renewals are also not allowed if they are the same as or similar to previous BIRT awards, reinforcing the one-time, pilot, team-building intent of the mechanism.

The timeline information in the posted announcement shows it was released on October 8, 2008, with an original (and current) closing date of February 19, 2009, and an archive date of March 22, 2009. Awards were contingent on the availability of funds and the submission of meritorious applications. The CFDA number associated with the program is 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research), and there is no cost sharing or matching requirement. For applicants seeking the full official text, NIAMS provided a link through the NIH Grants Guide, and NIH Office of Extramural Research contact information was listed for technical access issues.

Frequently Asked Questions (FAQs)

What is the NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards (R01) opportunity?

The NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards (R01) is a National Institutes of Health (NIH) program run by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). It provides short-term, competitive revision support to existing, active NIAMS-funded R01 projects to spark new and genuinely interdisciplinary collaborations.

What is the Funding Opportunity Number (FOA) for this program?

The Funding Opportunity Number is RFA-AR-09-001.

Is this a new standalone R01 grant?

No. This opportunity is not a new standalone R01. It uses the NIH revision mechanism to an existing NIAMS R01 (previously known by many investigators as a competitive supplement). The application is submitted as a revision to an active parent R01 award.

What is the main goal of the BIRT revision awards?

The central goal is to catalyze new, innovative interdisciplinary partnerships by enabling an established NIAMS R01-funded project to bring in a new partner (or partners) from a different discipline. The collaboration should allow the team to tackle a shared scientific problem in a way that would not be achievable by any investigator working alone.

What kind of collaborations is NIAMS trying to encourage?

NIAMS is specifically aiming to launch new, genuinely interdisciplinary collaborations that meaningfully expand the scientific scope of the parent R01 by adding expertise and methods not already present in the funded project. The collaboration is expected to be innovative, potentially high-impact, and may involve higher risk than conventional approaches, with the expectation of substantial payoff.

What scientific areas does this FOA target?

The FOA targets interdisciplinary work in NIAMS mission-relevant areas and highlights cross-cutting themes selected to pilot the BIRT concept. The solicited areas include autoimmunity, gender and sex factors, systems biology, developmental biology, regenerative medicine, immunology, soft tissue biology, imaging technologies, and tissue engineering.

Can you give examples of the types of interdisciplinary pairings NIAMS is looking for?

The announcement emphasizes connecting complementary strengths across domains. Examples described include pairing immunology and systems biology to address autoimmune mechanisms, or combining tissue engineering with imaging technologies to better track regenerative processes. The key requirement is that the collaboration adds new capabilities and expands the parent R01 beyond what it already includes.

Who is eligible to apply under RFA-AR-09-001?

Eligibility is tied to the parent award. Only investigators who already hold an active NIAMS R01 are eligible to submit an application under this FOA, because the application is a revision to that existing grant.

Do collaborators have to be funded by NIAMS?

No. The program is designed to encourage NIAMS R01 principal investigators to build new collaborations with independent investigators from other disciplines, whether those collaborators are funded by NIAMS, other NIH institutes and centers, or entirely different funding agencies.

Are multiple PDs/PIs allowed on the application?

Yes. Multiple PDs/PIs are allowed, which supports team science proposals where leadership is shared across disciplines.

What is the maximum project period for the revision award?

NIAMS planned to provide up to one year of additional support per BIRT revision award.

What is the funding cap for this revision award?

Direct costs are capped at $100,000 for the revision.

How much total funding did NIAMS plan to commit to the BIRT program for FY 2009?

NIAMS anticipated committing about $1 million in direct costs in fiscal year 2009.

How many awards did NIAMS expect to make?

NIAMS expected to support up to 10 total BIRT awards across two parallel announcements.

What are the two parallel BIRT announcements mentioned?

The two parallel announcements are this R01 revision FOA (RFA-AR-09-001) and a companion FOA (RFA-AR-09-002) that uses larger, multi-project or cooperative agreement mechanisms (U01, U54, P01, P50, P60) but has the same scientific scope.

How much time must remain on the parent NIAMS R01 to be eligible?

The parent NIAMS R01 must have enough time remaining to allow the collaboration to be developed and tested. In this announcement, NIAMS specified that the parent grant should not end earlier than January 31, 2011.

Can an applicant submit more than one BIRT application?

Yes. An applicant can submit more than one BIRT application as long as each is scientifically distinct.

Is there a limit on how many BIRT applications can be submitted per parent R01?

Yes. Only one BIRT application may be submitted per active NIAMS R01.

Can the revision be used to fund a collaboration that is already part of the parent grant?

No. NIAMS states that the revision cannot be used to fund collaborations that are already formal, ongoing components of the parent grant or other funded projects. The intent is to launch a new interdisciplinary partnership, not to continue one already underway.

Are resubmissions allowed under this FOA?

No. Resubmissions are not permitted.

Are renewals allowed for the same or similar BIRT award?

No. Renewals are not allowed if they are the same as or similar to previous BIRT awards, reinforcing the one-time, pilot, team-building intent of the mechanism.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

What are the key dates listed in the announcement?

The FOA was released on October 8, 2008. The closing date listed was February 19, 2009. The archive date was March 22, 2009.

Were awards guaranteed?

No. Awards were contingent on the availability of funds and the submission of meritorious applications.

What is the CFDA number associated with this program?

The CFDA number listed is 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research).

Where could applicants find the full official text and help for technical access issues?

NIAMS provided a link through the NIH Grants Guide for the full official text, and NIH Office of Extramural Research contact information was listed for technical access issues.

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