NIDA Research Center of Excellence Grant Program (P50) | Apply Online

Opportunity Summary:

The NIDA Research Center of Excellence Grant Program (P50) is a National Institutes of Health funding opportunity designed to support high-impact research Centers focused on drug abuse and addiction within any area of NIDA's mission. The program is aimed at building Centers that do more than run a set of related projects; it is meant to create a tightly connected, multidisciplinary research enterprise where investigators work across disciplines in a coordinated way, using a shared scientific theme that makes the whole Center stronger than the sum of its parts. NIDA is explicitly looking for bold, innovative science that can shift or transform understanding in the fields being studied, rather than incremental extensions of existing work. A central expectation is that the Center structure itself is essential to accomplishing the proposed research goals, meaning applicants should show why a P50 Center model, with integrated projects and shared resources, is needed instead of separate standalone grants.

A defining feature of this opportunity is the emphasis on synergy, thematic integration, and national resource value. Successful Centers are expected to generate major research advances and also function as national resources for the broader drug abuse research community. That includes sharing research findings, making data and resources available, and engaging in educational and outreach activities that reach multiple audiences such as other researchers, educational organizations, the general public, and policy makers. In practice, this means the Center should not only conduct strong research but also demonstrate a credible plan for dissemination, collaboration, and community or stakeholder engagement in ways that extend the Center's influence beyond the host institution.

The FOA also places strong weight on developing the next generation of scientists. P50 Centers funded under this program are expected to support education, training, and mentoring, giving new investigators meaningful roles within Center projects rather than token participation. This aligns with the broader goal of building long-term capacity in the addiction research workforce, ensuring that early-career researchers gain experience working in complex, team-based science environments and have access to mentorship and infrastructure that accelerates their development.

From a funding and administrative standpoint, the mechanism used is the Research Center of Excellence Grant (P50). The announcement states that the total funding available and the anticipated number of awards are not fixed and will depend on the number of applications received, their scientific quality, the proposed project durations, and the requested costs. There is no cost sharing or matching requirement, which removes a common barrier for organizations that might not have non-federal funds available to commit.

Eligibility is broad and includes many types of organizations and governmental entities. Eligible applicants include public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other than small businesses), and a variety of government bodies such as state governments, county governments, city or township governments, special district governments, and certain housing authorities. The FOA also recognizes and includes tribal governments and tribal organizations, including federally recognized tribal governments and other tribal entities, as well as tribally controlled colleges and universities. Additional explicitly eligible groups include historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This breadth reflects an intent to encourage strong Center applications from diverse institutional settings, including those serving populations disproportionately affected by substance use and addiction.

Key administrative details for this specific opportunity include the funding opportunity number PAR-10-189, the CFDA number 93.279 (Drug Abuse and Addiction Research Programs), and the posting date of May 6, 2010. The original and current closing date listed is January 7, 2013, with an archive date of February 7, 2013, meaning the opportunity is no longer open in the form provided here, though similar NIDA Center initiatives may appear under newer announcements. The full announcement was linked through the NIH Grants Guide, and technical assistance for accessing the announcement was directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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