Opportunity Information: Apply for RFA DC 17 001
Apply for RFA DC 17 001
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "NIDCD National Human Ear Tissue Laboratory Resource for Hearing and Balance Research (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173,.
- This funding opportunity was created on Jan 13, 2016 and posted on Jan 13, 2016.
- Applicants must submit their applications by Mar 31, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $475,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses.
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Opportunity Summary:
The NIDCD National Human Ear Tissue Laboratory Resource for Hearing and Balance Research (U24) opportunity (RFA-DC-17-001) is a National Institutes of Health cooperative agreement intended to create a single, nationally accessible laboratory resource that supports researchers studying hearing and balance using human middle and inner ear tissues. The central goal is to strengthen and standardize access to high-quality human ear specimens and specialized technical expertise, so that basic, translational, and clinical investigators can better connect findings from animal models to the human ear and, ultimately, to patient care aligned with the NIDCD mission to prevent, detect, diagnose, and treat deafness and other communication disorders.
Under this award, the funded laboratory is expected to function as a technology and service hub for the auditory and vestibular research community. A major part of the work is practical and infrastructure-focused: procuring post-mortem human temporal bones, preparing and processing these specimens, sectioning tissues to research-ready formats, and distributing high-quality human ear tissues to investigators. In addition to routine preparation and distribution, the laboratory is expected to continuously improve and share methods that enhance tissue preservation and enable better imaging of the human middle and inner ear. This includes imaging and visualization approaches that can capture fine-scale anatomy and biology, such as cellular structures and delicate membranous components that are essential for understanding both normal function and disease.
A key feature of the program is training and dissemination. The resource is not only meant to provide specimens; it is also meant to spread highly specialized know-how that is difficult for individual labs to build on their own. The FOA highlights providing opportunities for technical instruction in the unique skills required to prepare, handle, and use post-mortem human temporal bone and ear tissues. In practice, this kind of instruction can help expand the number of research groups capable of working effectively with these rare and technically demanding specimens, improving consistency and reproducibility across the field.
Because this is a cooperative agreement (U24), NIH involvement is expected to be more hands-on than in a standard research grant. The award mechanism is designed to actively coordinate interactions between the resource laboratory and the broader research community, with an emphasis on maximizing scientific impact and encouraging novelty while also avoiding unnecessary duplication of efforts across institutions. In other words, the funded group would be expected to operate as a coordinated national resource, responsive to community needs and aligned with NIDCD priorities, rather than as a standalone project serving only local collaborators.
Administrative details from the notice indicate this is a discretionary health funding opportunity administered by HHS/NIH (Agency: HHS-NIH11) under CFDA 93.173. Eligible applicants are broad and include various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, nonprofits with or without 501(c)(3) status, and for-profit organizations (excluding small businesses). The FOA anticipated a single award (Expected Awards: 1) with an award ceiling of $475,000. The opportunity was posted January 13, 2016, created the same day, and had an application closing date of March 31, 2016.
Frequently Asked Questions (FAQs)
What is the NIDCD National Human Ear Tissue Laboratory Resource for Hearing and Balance Research (U24)?
It is a National Institutes of Health (NIH) cooperative agreement (U24) opportunity intended to create a single, nationally accessible laboratory resource that supports hearing and balance researchers by providing access to human middle and inner ear tissues and specialized technical expertise.
What is the FOA number for this opportunity?
The funding opportunity announcement (FOA) is RFA-DC-17-001.
Which NIH Institute is associated with this opportunity?
This opportunity is associated with NIDCD (the National Institute on Deafness and Other Communication Disorders).
What is the main goal of the funded resource?
The central goal is to strengthen and standardize access to high-quality human ear specimens and specialized technical expertise so researchers can better connect findings from animal models to the human ear and ultimately support patient care aligned with the NIDCD mission.
What research areas does the resource support?
The resource is intended to support hearing and balance research, including basic, translational, and clinical investigations that use human middle and inner ear tissues.
What kinds of human tissues are involved?
The program focuses on human middle and inner ear tissues, including post-mortem human temporal bones that can be prepared and processed into research-ready tissue formats.
What does it mean that this is a "single, nationally accessible" resource?
It means the award is intended to support one centralized laboratory that serves as a national resource for the broader auditory and vestibular research community, rather than multiple separate regional resources.
How many awards were expected under this FOA?
The FOA anticipated a single award (Expected Awards: 1).
What is the maximum award amount mentioned in the notice?
The award ceiling listed for this opportunity is $475,000.
What is the award mechanism, and why does it matter?
The mechanism is a U24 cooperative agreement. This matters because NIH involvement is expected to be more hands-on than for a standard research grant, with active coordination and interaction between NIH, the resource laboratory, and the broader research community.
What role is the funded laboratory expected to play for the research community?
The funded laboratory is expected to function as a technology and service hub for the auditory and vestibular research community by procuring, preparing, processing, sectioning, and distributing high-quality human ear tissues, while also sharing specialized methods and expertise.
What practical activities are expected of the funded laboratory?
Key expected activities include procuring post-mortem human temporal bones, preparing and processing specimens, sectioning tissues into research-ready formats, and distributing high-quality human ear tissues to investigators.
Is the resource expected to improve laboratory methods over time?
Yes. The laboratory is expected to continuously improve and share methods that enhance tissue preservation and enable better imaging and visualization of the human middle and inner ear.
What types of imaging or visualization improvements are emphasized?
The FOA emphasizes imaging and visualization approaches capable of capturing fine-scale anatomy and biology, including cellular structures and delicate membranous components important for understanding normal function and disease.
Does the program include training and dissemination activities?
Yes. A key feature is training and dissemination of specialized know-how, including opportunities for technical instruction in skills needed to prepare, handle, and use post-mortem human temporal bone and ear tissues.
Why is training considered a key feature of this resource?
Because the techniques needed to work with these rare and technically demanding specimens can be difficult for individual labs to develop independently, training helps expand the number of groups able to use the tissues effectively and can improve consistency and reproducibility across the field.
How is this resource expected to interact with the broader research community?
As a cooperative agreement, it is designed to actively coordinate interactions between the resource laboratory and the research community, aiming to maximize scientific impact, encourage novelty, and avoid unnecessary duplication of efforts across institutions.
Is this resource intended to operate like a standalone research project?
No. The funded group is expected to operate as a coordinated national resource that is responsive to community needs and aligned with NIDCD priorities, rather than serving only local collaborators.
Which federal agency administers this funding opportunity?
The opportunity is administered by HHS/NIH (Agency: HHS-NIH11).
What is the CFDA number listed for this opportunity?
The CFDA number provided is 93.173.
What type of funding opportunity is this described as?
It is described as a discretionary health funding opportunity.
Who is eligible to apply based on the notice?
Eligible applicants are broad and include various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, nonprofits with or without 501(c)(3) status, and for-profit organizations (excluding small businesses).
Are small businesses eligible to apply?
No. The eligibility description includes for-profit organizations but explicitly excludes small businesses.
Are tribal entities eligible to apply?
Yes. Federally recognized tribal governments and other tribal organizations are included as eligible applicants.
Are nonprofit organizations required to have 501(c)(3) status to be eligible?
No. The eligibility list includes nonprofits with or without 501(c)(3) status.
When was this opportunity posted?
The opportunity was posted on January 13, 2016.
When was the opportunity created?
The notice indicates it was created on January 13, 2016.
What was the application closing date listed for this FOA?
The application closing date was March 31, 2016.
What is the intended scientific impact of providing human ear tissue resources?
The resource is intended to help investigators connect discoveries from animal models to the human ear, strengthening translational relevance and supporting progress toward patient care aligned with the NIDCD mission to prevent, detect, diagnose, and treat deafness and other communication disorders.
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