Opportunity Information: Apply for PAR 11 003
Apply for PAR 11 003
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
- This funding opportunity was created on Oct 21, 2013 and posted on Oct 8, 2010.
- Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Special district governments Small businesses Private institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01) opportunity (Funding Opportunity Number PAR-11-003) is an NIH discretionary grant program designed to move strong basic science discoveries toward practical clinical tools in the Institute's core mission areas: hearing, balance, smell, taste, voice, speech, and language. The central idea is to speed up the path from laboratory findings to real-world methods that clinicians can use to improve human health, particularly through advances that affect the diagnosis, treatment, or prevention of communication disorders. Rather than supporting purely exploratory basic work or late-stage clinical validation, this program sits in the middle "translational" space where mechanistic insights are shaped into clinically meaningful tools, approaches, or technologies.
A major emphasis of the FOA is collaboration. NIDCD is explicitly encouraging teams that bring together basic scientists with clinicians and clinical scientists so that projects are grounded in both biological understanding and real clinical need. Applications that involve multi-institutional and multidisciplinary efforts are welcomed, and partnerships between academic groups and industry are encouraged as well, reflecting the reality that many clinical tools (such as diagnostics, devices, software-based assessments, or therapeutic platforms) often require cross-sector expertise to reach a stage where they can plausibly be deployed in healthcare settings. In practical terms, competitive projects under this FOA would typically show a clear line of sight from a well-supported basic discovery to a defined clinical tool concept, along with a development and testing plan that demonstrates feasibility and clinical relevance.
The scope is intentionally focused on translation that has a credible and direct connection to a clinical condition. Applicants are expected to clearly establish why the proposed tool matters clinically, what gap it fills, and how the work will lead to an outcome with practical clinical impact. That usually means the project should not end at a general proof-of-concept in a model system without a clear application, and it also should not be so early that it is still "pre-translational" (for example, generating foundational knowledge without a defined tool-development pathway). At the same time, the FOA is not meant to fund outcome studies (such as large-scale effectiveness trials), extensions of ongoing clinical research studies, or efforts that mainly fine-tune existing clinical protocols. The goal is to create a new avenue for tool-building translation, not to support incremental optimization of what is already in widespread use, and not to serve as a mechanism for late-stage clinical outcomes research.
From an administrative standpoint, this is an NIH R01 grant mechanism under the Health funding activity category, linked to CFDA number 93.173 (Research Related to Deafness and Communication Disorders). The opportunity does not require cost sharing or matching. The announcement was posted October 8, 2010, with key dates showing an original closing date of October 22, 2013, a current closing date of November 1, 2013, and an archive date of December 1, 2013, indicating the specific listing reflects a past cycle of the FOA.
Eligibility is broad and includes many types of applicants, reflecting NIH's general openness to strong scientific proposals regardless of organizational type. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, with distinctions noted), for-profit organizations (including small businesses), and a wide range of government entities such as state, county, city/township, special district governments, and independent school districts. The eligibility list also extends to tribal organizations and tribal governments (federally recognized and other than federally recognized), public housing authorities/Indian housing authorities, and other categories. Additional eligible applicants explicitly include Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and non-U.S. entities (foreign organizations), which signals that international participation is allowed where appropriate and consistent with NIH policy.
The sponsoring agency is the National Institutes of Health, with the programmatic focus housed in NIDCD. The full announcement and details were provided through the NIH Grants Guide (linked in the source data as http://grants.nih.gov/grants/guide/pa-files/PAR-11-003.html). For access or technical issues related to the electronic announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01) opportunity?
This opportunity (Funding Opportunity Number PAR-11-003) is an NIH discretionary grant program that uses the R01 mechanism to support projects that move strong basic research discoveries toward practical clinical tools within the National Institute on Deafness and Other Communication Disorders (NIDCD) mission areas.
What is the main purpose of this funding opportunity?
The purpose is to speed translation from laboratory findings into real-world methods clinicians can use to improve human health, especially advances that affect the diagnosis, treatment, or prevention of communication disorders. The program is designed to occupy the mid-stage "translational" space where mechanistic insights are shaped into clinically meaningful tools, approaches, or technologies.
Which scientific and clinical areas are included in NIDCD's core mission for this FOA?
The FOA focuses on NIDCD mission areas: hearing, balance, smell, taste, voice, speech, and language.
What types of outcomes is the FOA trying to produce?
Projects are expected to produce clinically meaningful tools, approaches, or technologies grounded in basic science discoveries, with a credible and direct connection to a clinical condition and a clear path toward practical clinical impact.
What stage of research is this FOA intended to support?
This FOA targets mid-stage translation: work that is beyond purely exploratory basic research but not yet at late-stage clinical validation or large outcomes testing. The emphasis is on taking a well-supported basic discovery and shaping it into a defined clinical tool concept with a feasibility-focused development and testing plan.
Does this FOA support purely exploratory basic research?
No. The FOA is not intended to support purely exploratory basic work without a defined pathway to a clinical tool.
Does this FOA support late-stage clinical validation or large-scale effectiveness trials?
No. The FOA is not meant to fund outcome studies such as large-scale effectiveness trials.
Does this FOA fund extensions of ongoing clinical studies?
No. The FOA is not intended to fund extensions of ongoing clinical research studies.
Does this FOA support incremental improvements to existing clinical protocols?
No. The FOA is not intended primarily for projects that mainly fine-tune existing clinical protocols or provide incremental optimization of methods already in widespread use.
What is meant by the "translational space" in this FOA?
It refers to the middle stage between early, discovery-focused basic research and late-stage clinical outcomes research. In this space, mechanistic insights are translated into concrete clinical tool concepts, along with plans for development and testing that demonstrate feasibility and clinical relevance.
How important is clinical relevance in the application?
Clinical relevance is central. Applicants are expected to clearly establish why the proposed tool matters clinically, what clinical gap it fills, and how the work will lead to an outcome with practical clinical impact.
What does the FOA say about proof-of-concept work?
The FOA indicates that projects should not end at a general proof-of-concept in a model system without a clear clinical application. The work should maintain a defined clinical tool-development pathway.
What does the FOA say about projects that are too early-stage?
The FOA suggests it should not be so early that it is still "pre-translational," such as work focused on generating foundational knowledge without a defined tool-development pathway.
Is collaboration encouraged?
Yes. A major emphasis of the FOA is collaboration, with NIDCD explicitly encouraging teams that bring together basic scientists with clinicians and clinical scientists.
Are multi-institutional and multidisciplinary applications allowed?
Yes. Applications involving multi-institutional and multidisciplinary efforts are welcomed.
Are partnerships between academia and industry encouraged?
Yes. Partnerships between academic groups and industry are encouraged, reflecting that many clinical tools (including diagnostics, devices, software-based assessments, or therapeutic platforms) often require cross-sector expertise to become plausibly deployable in healthcare settings.
What kinds of clinical tools are implied by the FOA?
The FOA references clinical tools such as diagnostics, devices, software-based assessments, and therapeutic platforms, as examples of the types of outputs that may require cross-sector development to move toward healthcare deployment.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R01 grant mechanism under the Health funding activity category.
What is the CFDA number associated with this opportunity?
The CFDA number is 93.173 (Research Related to Deafness and Communication Disorders).
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH), with the programmatic focus housed in the National Institute on Deafness and Other Communication Disorders (NIDCD).
What is the Funding Opportunity Number?
The Funding Opportunity Number is PAR-11-003.
When was this announcement posted, and what are the key dates?
The announcement was posted on October 8, 2010. Key dates listed include an original closing date of October 22, 2013, a current closing date of November 1, 2013, and an archive date of December 1, 2013, indicating this listing reflects a past cycle of the FOA.
Is this a current or archived opportunity based on the provided dates?
Based on the listed close dates in 2013 and an archive date of December 1, 2013, the specific listing described reflects a past cycle of the FOA.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, with distinctions noted), and for-profit organizations (including small businesses). A wide range of government entities are also eligible, including state, county, city/township, special district governments, and independent school districts.
Are tribal organizations and tribal governments eligible?
Yes. Eligibility includes tribal organizations and tribal governments (federally recognized and other than federally recognized), and public housing authorities/Indian housing authorities.
Are minority-serving institutions and community-based organizations eligible?
Yes. Additional eligible applicants explicitly include Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and regional organizations.
Can federal agencies apply?
Yes. The eligibility list includes eligible federal agencies.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are included in the eligibility list.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list includes non-U.S. entities (foreign organizations), signaling that international participation is allowed where appropriate and consistent with NIH policy.
Where can applicants find the full announcement?
The full announcement and details are provided through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-11-003.html
Who is listed as a contact for access or technical issues with the electronic announcement?
For access or technical issues related to the electronic announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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