Opportunity Information: Apply for PAR 11 004
Apply for PAR 11 004
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCD Research Grants for Translating Basic Research into Clinical Tools (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
- This funding opportunity was created on Oct 21, 2013 and posted on Oct 8, 2010.
- Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: For profit organizations other than small businesses County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education City or township governments Independent school districts Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIDCD Research Grants for Translating Basic Research into Clinical Tools (R21) (Funding Opportunity Number PAR-11-004) is a National Institutes of Health discretionary grant program designed to push promising basic science discoveries into practical, clinically useful tools within NIDCD mission areas. These areas include hearing, balance, smell, taste, voice, speech, and language, with an overarching goal of improving human health by enabling better diagnosis, treatment, and prevention of communication disorders. The program is explicitly meant to create a pathway for basic scientists, clinicians, and clinical scientists to come together early and jointly carry out translational projects that have a clear clinical target and a realistic path toward real-world use.
At its core, this opportunity supports projects that bridge the gap between laboratory findings and clinical utility. The FOA emphasizes the development or advancement of clinical tools rather than purely exploratory or mechanistic work. In practice, that means applicants need to show how a basic research insight will be converted into something that can be used in a clinical setting, such as a diagnostic approach, assessment method, device concept, intervention strategy, or other implementable tool that could plausibly affect patient care or clinical decision-making in an NIDCD-relevant condition. A key expectation is that the connection to the clinical condition is direct and well supported, and that the end products of the proposed work are positioned to have tangible clinical impact rather than simply generating additional preliminary scientific data.
The announcement strongly encourages collaborative approaches, including multi-institutional and multidisciplinary teams, as well as academic-industry partnerships. The intent here is straightforward: translation typically requires combined expertise (for example, basic biology plus engineering plus clinical workflows, or biomarker discovery plus assay development plus validation planning), and the FOA signals that proposals built around integrated teams and shared translational aims are welcome. This also suggests that projects that require specialized platforms, access to patient populations, or industry-style development capabilities can be competitive when the collaboration is well justified and clearly managed.
Just as important as what the FOA supports is what it does not support. It is not intended for outcome studies, for extending ongoing clinical research studies, for optimizing existing clinical protocols, or for pre-translational work that is still too far upstream from practical clinical use. In other words, projects that primarily evaluate long-term patient outcomes, simply add more participants to an already-running clinical study, fine-tune established procedures without introducing a genuinely new tool, or remain at the stage of basic discovery without a credible plan for translation would not match the program’s scope. The overall expectation is that the proposed work sits squarely in the translational middle ground: beyond pure discovery, but focused on generating an actual tool or capability that clinicians could eventually use.
From an administrative standpoint, this is an NIH grant using the R21 activity code, which is commonly associated with early-stage, exploratory, or developmental projects that can establish feasibility and momentum for subsequent larger-scale work. The listed award ceiling is $200,000, and there is no cost sharing or matching requirement. The program is tied to CFDA number 93.173 (Research Related to Deafness and Communication Disorders). The opportunity was posted October 8, 2010, with key dates in the record including an original closing date of October 22, 2013 and a current closing date of November 1, 2013, and it was archived December 1, 2013.
Eligibility is broad and includes a wide range of organization types: public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses), local and state governments, tribal governments and tribal organizations, special district governments, independent school districts, public housing authorities/Indian housing authorities, and additional categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations. This wide eligibility aligns with the FOA’s emphasis on cross-sector collaboration and the practical realities of translating research into clinically usable tools.
The full announcement is available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-11-004.html. For technical difficulties accessing the announcement or linking issues, the listed contact is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the NIDCD Research Grants for Translating Basic Research into Clinical Tools (R21) opportunity?
This is an NIH discretionary grant program (Funding Opportunity Number PAR-11-004) from the National Institute on Deafness and Other Communication Disorders (NIDCD). It supports projects that move promising basic research discoveries toward practical clinical tools that could be used in real-world healthcare settings.
What is the main purpose of this FOA?
The purpose is to create a clear pathway for translation by bringing basic scientists, clinicians, and clinical scientists together early to develop projects with a direct clinical target and a realistic path toward eventual clinical use.
Which mission areas does NIDCD consider relevant for this grant?
NIDCD mission areas called out in the announcement include hearing, balance, smell, taste, voice, speech, and language, with an overall goal of improving diagnosis, treatment, and prevention of communication disorders.
What type of work is this grant meant to support?
The FOA emphasizes bridging the gap between laboratory findings and clinical utility. Projects should focus on developing or advancing a clinically useful tool rather than staying in purely exploratory or mechanistic basic research.
What kinds of "clinical tools" are examples of what the FOA is looking for?
Based on the description, appropriate end products could include a diagnostic approach, an assessment method, a device concept, an intervention strategy, or another implementable tool that could plausibly influence patient care or clinical decision-making in an NIDCD-relevant condition.
How direct does the link to a clinical condition need to be?
The FOA expects a direct, well-supported connection to a clinical condition and an end product positioned for tangible clinical impact, rather than a project designed mainly to generate additional preliminary scientific data.
Does this program support purely basic discovery or mechanistic research?
No. The program is intended for translational work focused on creating or advancing a clinical tool, not for projects that remain too far upstream at the basic discovery stage without a credible plan for translation.
Does this FOA support outcome studies?
No. The announcement explicitly states it is not intended for outcome studies.
Can this funding be used to extend an ongoing clinical research study?
No. The FOA states it is not intended for extending ongoing clinical research studies (for example, simply adding more participants to an already-running study).
Is optimizing existing clinical protocols within scope?
No. The FOA indicates it is not intended for optimizing existing clinical protocols, particularly when the work does not introduce a genuinely new clinical tool.
Where does this opportunity sit on the research-to-practice spectrum?
It is described as sitting in the translational "middle ground": beyond pure discovery, but focused on generating an actual tool or capability that clinicians could eventually use.
Are collaborative and multidisciplinary proposals encouraged?
Yes. The FOA strongly encourages collaborative approaches, including multi-institutional and multidisciplinary teams, as well as academic-industry partnerships.
Why does the FOA encourage academic-industry partnerships and multi-institution teams?
The rationale provided is that translation often requires combined expertise and resources, such as engineering capabilities, clinical workflow knowledge, access to patient populations, specialized platforms, and development capabilities more commonly found across multiple groups or sectors.
What NIH activity code is used for this opportunity, and what does it imply?
This opportunity uses the NIH R21 activity code, which is commonly associated with early-stage, exploratory, or developmental projects intended to establish feasibility and generate momentum for later, larger-scale work.
What is the funding ceiling for awards under this FOA?
The listed award ceiling is $200,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What is the CFDA number associated with this program?
The program is tied to CFDA 93.173, titled Research Related to Deafness and Communication Disorders.
Who is eligible to apply?
Eligibility is broad and includes many organization types, such as public and private institutions of higher education; nonprofit organizations (501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); local and state governments; tribal governments and tribal organizations; special district governments; independent school districts; public housing authorities/Indian housing authorities; and various institution categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, and faith-based or community-based organizations.
Are U.S. territories and non-U.S. organizations eligible?
Yes. The eligibility list includes U.S. territories or possessions and also includes non-U.S. entities (foreign organizations) and regional organizations.
What are the key dates listed for this opportunity?
The record lists a posted date of October 8, 2010, an original closing date of October 22, 2013, a current closing date of November 1, 2013, and an archived date of December 1, 2013.
Where can applicants find the full official announcement?
The full announcement is available in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-11-004.html
Who should be contacted for technical issues accessing the announcement link?
For technical difficulties accessing the announcement or linking issues, the listed contact is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
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