Opportunity Information: Apply for PAR 13 044
Apply for PAR 13 044
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Small Research Grants for Data Analysis and Statistical Methodology Applied to Genome wide Data (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
- This funding opportunity was created on Dec 14, 2012 and posted on Dec 14, 2012.
- Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) County governments Special district governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses State governments City or township governments Independent school districts Small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity titled "NIDCR Small Research Grants for Data Analysis and Statistical Methodology Applied to Genome wide Data (R03)" (Funding Opportunity Number PAR-13-044) is a discretionary NIH grant program administered under the National Institute of Dental and Craniofacial Research (NIDCR). It is designed to fund smaller, focused projects that make use of existing genome-wide datasets, rather than generating new large-scale genomic data from scratch. The central emphasis is on secondary analysis of genome-wide data, such as data produced from genome-wide association studies (GWAS) or similar genome-wide platforms, when the research question is clearly tied to human dental or craniofacial conditions or traits. In addition to straightforward secondary analyses, the announcement also explicitly welcomes proposals aimed at developing or refining statistical methods that are well-suited for genome-wide data analysis, again with the expectation that the methodological work will be relevant to dental and craniofacial research problems.
The scientific scope is anchored in oral and craniofacial health, corresponding to CFDA 93.121 (Oral Diseases and Disorders Research). In practical terms, this means the program is looking for projects that can use already-available genome-wide datasets to advance understanding of the genetic architecture, risk factors, or biological pathways associated with dental or craniofacial traits and disorders. Examples of the types of work that typically fit this kind of announcement include reanalyzing GWAS datasets to test new hypotheses, conducting meta-analyses across multiple existing cohorts, performing stratified or subgroup analyses that were not part of the original study aims, applying improved quality control or imputation strategies to legacy genomic data, or integrating genome-wide variant data with phenotype definitions relevant to craniofacial development or oral disease. On the methodology side, the opportunity supports development of analytical approaches for challenges common in genome-wide studies, such as population stratification, rare variant aggregation, multiple-testing burdens, phenotype heterogeneity, gene-environment interactions, multi-trait modeling, or methods that improve interpretability and reproducibility in genome-wide inference, as long as the methodological innovation is positioned to benefit dental or craniofacial genomics.
This funding opportunity uses the NIH R03 mechanism, which is the Small Research Grant mechanism. R03 awards are generally intended to support discrete, well-defined projects that can be completed with a limited budget and within a relatively short project period compared to larger NIH mechanisms. While the announcement text provided does not list budget caps or project duration, the defining feature from the applicant perspective is that proposals should be tightly scoped, realistic, and clearly framed around using existing genome-wide data resources or creating analytic/statistical methodology that can be demonstrated on genome-wide data relevant to NIDCR interests. Cost sharing or matching is not required, which reduces administrative burden for applicants and makes the program accessible to a wide range of organizations.
Eligibility for this opportunity is broad. The eligible applicant types include public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, and multiple levels of government including state, county, city or township governments, special district governments, independent school districts, and certain housing authorities. The eligibility language also highlights that a wide range of mission-driven and capacity-building institutions may apply, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Importantly, the program allows non-U.S. entities to apply: foreign organizations and foreign institutions are eligible, and non-domestic components of U.S. organizations may participate. Foreign components, as defined by NIH policy, are also permitted, signaling that international collaboration or analysis performed in non-U.S. settings can be appropriate when justified scientifically and consistent with NIH grants policy.
From an administrative timeline standpoint, the opportunity was posted on December 14, 2012, and the original and final closing date listed is January 7, 2016, with an archive date of February 7, 2016. That means the specific FOA in this form is no longer open for applications, but the summary remains useful as a description of the kind of work NIDCR has sought to stimulate: efficient, hypothesis-driven secondary analyses of existing genome-wide datasets and targeted methodological development that strengthens the genomic analysis toolkit for dental and craniofacial research.
For applicants or organizations trying to locate the full archived announcement or confirm details, the FOA points to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/pa-files/PAR-13-044.html). The contact information provided is primarily technical support through the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV) for access or linking issues, indicating that scientific or programmatic questions would typically be handled through the standard NIH program contact structure listed in the full FOA.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "NIDCR Small Research Grants for Data Analysis and Statistical Methodology Applied to Genome wide Data (R03)" and the Funding Opportunity Number is PAR-13-044.
Which agency and institute administer this program?
This is an NIH discretionary grant program administered under the National Institute of Dental and Craniofacial Research (NIDCR).
What is the main purpose of this funding opportunity?
The central purpose is to support small, focused projects that use existing genome-wide datasets for secondary analysis, or that develop/refine statistical methods for analyzing genome-wide data, when the work is clearly tied to human dental or craniofacial conditions or traits.
Does this program fund the generation of new large-scale genomic data?
No. The emphasis is on using already-available genome-wide datasets rather than generating new large-scale genomic data from scratch.
What kinds of datasets are intended for use?
The opportunity emphasizes secondary analysis of genome-wide data, including data produced from genome-wide association studies (GWAS) or similar genome-wide platforms.
What research areas or conditions need to be addressed?
The research question must be clearly tied to human dental or craniofacial conditions or traits, within the broader scope of oral and craniofacial health.
What is the CFDA number associated with this opportunity?
The scientific scope is associated with CFDA 93.121 (Oral Diseases and Disorders Research).
What types of secondary analyses are examples of a good fit?
Examples described include reanalyzing GWAS datasets to test new hypotheses; conducting meta-analyses across multiple existing cohorts; performing stratified or subgroup analyses not included in the original study aims; applying improved quality control or imputation strategies to legacy genomic data; and integrating genome-wide variant data with phenotype definitions relevant to craniofacial development or oral disease.
Are statistical methodology projects allowed, or is it only applied data analysis?
Methodology projects are explicitly welcomed. Proposals may focus on developing or refining statistical methods suited for genome-wide data analysis, with the expectation that the methods are relevant to dental and craniofacial research problems and can be demonstrated on genome-wide data relevant to NIDCR interests.
What kinds of statistical or analytic challenges are highlighted as relevant?
The announcement highlights challenges common in genome-wide studies, including population stratification, rare variant aggregation, multiple-testing burdens, phenotype heterogeneity, gene-environment interactions, multi-trait modeling, and methods that improve interpretability and reproducibility in genome-wide inference.
What grant mechanism does this opportunity use?
This opportunity uses the NIH R03 mechanism (Small Research Grant).
What does the R03 mechanism imply about project scope?
R03 awards are intended for discrete, well-defined projects that are tightly scoped, realistic, and designed to be completed with a limited budget and within a relatively short project period compared to larger NIH mechanisms.
Does the provided announcement text list the budget cap or project duration?
No. The information provided notes that the announcement text does not list budget caps or project duration, but emphasizes the defining R03 feature of a small, focused, short project.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and multiple levels of government (including state, county, city or township governments, special district governments, independent school districts, and certain housing authorities).
Are mission-driven and capacity-building institutions specifically included?
Yes. The eligibility language highlights that HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, as well as faith-based or community-based organizations, are eligible.
Are federal agencies eligible?
Yes. Eligible federal agencies are included in the eligibility language.
Can foreign (non-U.S.) organizations apply?
Yes. Foreign organizations and foreign institutions are eligible to apply.
Can non-domestic components of U.S. organizations participate?
Yes. Non-domestic components of U.S. organizations may participate.
Are foreign components permitted under NIH policy?
Yes. Foreign components (as defined by NIH policy) are permitted, indicating that international collaboration or analysis performed in non-U.S. settings can be appropriate when justified scientifically and consistent with NIH grants policy.
When was this funding opportunity posted?
The opportunity was posted on December 14, 2012.
What were the closing dates and archive date?
The original and final closing date listed is January 7, 2016, and the archive date is February 7, 2016.
Is this specific FOA still open for applications?
No. Based on the closing and archive dates provided, this specific FOA in this form is no longer open for applications.
Why is the archived announcement still useful?
It remains useful as a description of the types of work NIDCR sought to stimulate: efficient, hypothesis-driven secondary analyses of existing genome-wide datasets and targeted methodological development that strengthens the genomic analysis toolkit for dental and craniofacial research.
Where can applicants find the full archived announcement?
The FOA points to the NIH Grants Guide page: http://grants.nih.gov/grants/guide/pa-files/PAR-13-044.html
Who is listed as the contact for technical issues with access or linking?
The contact information provided is for technical support through the NIH Office of Extramural Research (OER) webmaster: FBOWebmaster@OD.NIH.GOV.
Does the provided contact address scientific or programmatic questions?
The provided contact is primarily for technical support (access or linking issues). The information indicates that scientific or programmatic questions would typically be handled through the standard NIH program contact structure listed in the full FOA.
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