Opportunity Information: Apply for PAR 10 267

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIMH Research Education Grants (R25)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Aug 10, 2012 and posted on Aug 20, 2010.
  • Applicants must submit their applications by Aug 11, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Foreign institutions are not eligible to apply in response to this FOA. In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participants may gain relevant experiences consistent with their research interests and goals. Institutions with existing Ruth L. Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving NIH support. Moreover, the R25 mechanism is not intended to support long term training by NRSA eligible individuals and may not be used to circumvent or supplement Ruth L. Kirschstein NRSA research training mechanisms. If multiple sites are involved in the research education program, the applicant institution must be one of these sites for the program. The need for and use of multiple sites must be justified.
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Opportunity Summary:

The NIMH Research Education Grants (R25) opportunity (Funding Opportunity Number PAR-10-267) is a discretionary NIH grant program designed to help institutions create research education activities that build a stronger pipeline of mental health researchers aligned with the NIMH Strategic Plan. The central aim is not to fund stand-alone research projects, but to support structured, innovative educational programs that prepare participants to become investigators in NIMH-relevant scientific areas. NIMH signals that its priorities are intentionally broad, ranging from basic neuroscience and human genetics/genomics to translational science, clinical interventions, and mental health services research across the lifespan. In practice, this means applicants can propose many types of educational models as long as the focus is clearly tied to developing research talent in areas important to NIMH.

NIMH expresses particular interest in R25 proposals that go beyond routine coursework and instead create practical, high-impact training environments. Examples highlighted include short courses or workshops (often intensive and skills-based), research mentoring networks that connect trainees with experienced investigators, and programs embedded in medical school and/or residency that encourage the development of research-oriented physician-scientists. NIMH also emphasizes models that blend didactic instruction with sustained mentoring and real research exposure, suggesting that competitive applications will show how participants move from learning concepts to applying them through guided research experiences and ongoing career development support.

This FOA uses the NIH Research Education (R25) mechanism. An important administrative point is that research education programs funded under this mechanism generally cannot be transferred to another institution unless there is a strong justification. NIMH also notes that program scale can vary substantially across applicants, so award size and the number of awards are not fixed in advance; they depend on the volume of applications received and, importantly, their quality, duration, and cost structure.

Budget-wise, applications may request up to $250,000 per year in direct costs, and the total project period may not exceed five years. NIMH places a clear cap on staffing and administrative expenses: total personnel costs tied to directing, coordinating, administering, and implementing the program (including PD/PI salary and administrative/clerical support) must be reasonable, well-justified, and cannot exceed 25 percent of the requested direct costs each year. This signals that NIMH expects most funds to support education and participant-focused activities rather than program overhead.

Eligibility is broad across organization types, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses, with additional categories explicitly referenced such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, and Alaska Native and Native Hawaiian Serving Institutions. Foreign institutions are not eligible to apply under this FOA. If a program involves multiple sites, the applicant institution must be one of the participating sites, and the rationale for using multiple sites must be clearly justified (for example, unique expertise, participant access, or specialized resources at partner locations).

NIMH also clarifies how the R25 should fit into the broader NIH training ecosystem. The expectation is that an R25 program will often complement research training already happening at the institution, especially when faculty have active research projects that can provide hands-on experiences aligned with participant goals. At the same time, NIMH draws a firm boundary around the purpose of the R25: it is not meant to provide long-term training for NRSA-eligible individuals, and it cannot be used to circumvent, supplement, or substitute for Ruth L. Kirschstein NRSA training mechanisms such as institutional T32 programs. Institutions that already hold NRSA training grants may still apply, but they must demonstrate that the R25-supported educational experiences are distinct from NIH-supported training programs already in place.

Administrative details from the posting indicate there is no cost sharing or matching requirement, and the program is associated with CFDA 93.242 (Mental Health Research Grants). The opportunity was posted on August 20, 2010, and the archived record lists dates including an original closing date of September 25, 2012 and a current closing date of August 11, 2012, with an archive date of September 10, 2012. The full announcement is available through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-10-267.html, and support for access/linking issues is routed through the NIH Office of Extramural Research webmaster contact listed in the notice.

FAQs: NIMH Research Education Grants (R25) - PAR-10-267

What is this funding opportunity?

This is the NIMH Research Education Grants (R25) program under Funding Opportunity Number PAR-10-267. It is a discretionary NIH grant mechanism intended to help institutions build structured research education activities that strengthen the pipeline of mental health researchers aligned with the NIMH Strategic Plan.

What is the central purpose of an NIMH R25 award?

The central aim is to support innovative, structured educational programs that prepare participants to become investigators in scientific areas relevant to NIMH. It is designed to develop research talent and provide research education experiences, not to fund independent, stand-alone research projects.

Does the R25 mechanism fund stand-alone research projects?

No. The opportunity explicitly emphasizes that the goal is not to fund stand-alone research projects. The focus should be on research education and career development activities that move participants toward becoming investigators in NIMH-relevant areas.

What kinds of scientific areas does NIMH consider relevant for this R25?

NIMH indicates its priorities are intentionally broad and can include basic neuroscience, human genetics/genomics, translational science, clinical interventions, and mental health services research across the lifespan. Applicants may propose various educational models as long as they are clearly tied to developing research talent in areas important to NIMH.

What types of research education activities does NIMH highlight as competitive?

NIMH expresses particular interest in proposals that go beyond routine coursework and create practical, high-impact training environments. Examples highlighted include intensive short courses or workshops, research mentoring networks that connect trainees with experienced investigators, and programs embedded in medical school and/or residency that encourage development of research-oriented physician-scientists.

Is didactic instruction alone sufficient for an R25 program?

The FOA suggests NIMH values models that blend didactic instruction with sustained mentoring and real research exposure. Competitive applications are expected to show how participants progress from learning concepts to applying them through guided research experiences and ongoing career development support.

Can an R25 program be delivered across multiple sites?

Yes, multi-site programs are allowed, but the applicant institution must be one of the participating sites. The rationale for multiple sites must be clearly justified, such as unique expertise, improved participant access, or specialized resources available at partner locations.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply under this FOA.

What types of U.S. organizations are eligible to apply?

Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. The FOA also explicitly references institution types such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, and Alaska Native and Native Hawaiian Serving Institutions.

What is the maximum budget allowed?

Applications may request up to $250,000 per year in direct costs.

What is the maximum project period?

The total project period may not exceed five years.

Is there a cap on personnel and administrative costs?

Yes. Total personnel costs associated with directing, coordinating, administering, and implementing the program (including PD/PI salary and administrative/clerical support) must be reasonable, well-justified, and cannot exceed 25% of the requested direct costs each year.

Does NIMH set a fixed award size or a fixed number of awards?

No. NIMH indicates that award size and the number of awards are not fixed in advance. They depend on the volume of applications received and their quality, duration, and cost structure.

Can an awarded R25 program be transferred to another institution?

Generally, research education programs funded under the R25 mechanism cannot be transferred to another institution unless there is a strong justification.

How should the R25 program relate to other training and research activities at the institution?

NIMH expects R25 programs to often complement research training already happening at the institution, particularly when faculty have active research projects that can provide hands-on experiences aligned with participant goals.

Can this R25 be used to replace or supplement NRSA training programs (like T32)?

No. NIMH draws a firm boundary that the R25 is not meant to provide long-term training for NRSA-eligible individuals and cannot be used to circumvent, supplement, or substitute for Ruth L. Kirschstein NRSA training mechanisms such as institutional T32 programs.

Can an institution that already has NRSA training grants still apply for this R25?

Yes. Institutions that already hold NRSA training grants may still apply, but they must demonstrate that the R25-supported educational experiences are distinct from NIH-supported training programs already in place.

Is cost sharing or matching required?

No. The posting indicates there is no cost sharing or matching requirement.

What CFDA number is associated with this opportunity?

This program is associated with CFDA 93.242 (Mental Health Research Grants).

Where can applicants find the full funding announcement?

The full announcement is available through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-10-267.html.

What are the key dates shown in the archived posting?

The opportunity was posted on August 20, 2010. The archived record lists an original closing date of September 25, 2012, a current closing date of August 11, 2012, and an archive date of September 10, 2012.

Who should be contacted for technical problems accessing or linking to the announcement?

For access or linking issues, the notice routes support through the NIH Office of Extramural Research webmaster contact listed in the announcement.

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