Opportunity Information: Apply for PA 07 405
Apply for PA 07 405
- The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Nutrition and Alcohol Related Health Outcomes (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health.
- This funding opportunity was created on Dec 5, 2008 and posted on Jul 16, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized) Private institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Special district governments City or township governments County governments Independent school districts For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments).
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Nutrition and Alcohol Related Health Outcomes (R21) opportunity (Funding Opportunity Number PA-07-405) is a National Institutes of Health discretionary grant program designed to support exploratory, early-stage research on how nutrition influences alcohol-related health outcomes. It is sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and the NIH Office of Dietary Supplements (ODS). The central idea is to stimulate a wide range of studies that clarify whether and how dietary factors, nutrient status, or nutritional interventions affect the development, prevention, or treatment of problems linked to alcohol use, with work spanning both human and animal model research.
Scientifically, the program is interested in the connections between nutrition and a broad set of alcohol-related outcomes. This includes alcohol dependence and related behavioral or psychiatric co-morbidities, as well as chronic and acute disease processes and the ways alcohol affects organ function, injury, and recovery. In practice, that scope can cover many directions, such as whether specific nutrient deficiencies worsen alcohol-induced tissue damage, whether diet patterns change risk for alcohol-associated cancers or metabolic disease, or whether targeted supplementation or dietary interventions can improve outcomes for individuals with alcohol use disorder or those experiencing alcohol-related organ stress.
From a study-design standpoint, the FOA is intentionally flexible. Applicants can propose biomedical and mechanistic studies (including work in animal models), epidemiologic analyses that examine diet and alcohol exposure in populations, and intervention studies that test nutritional strategies aimed at prevention or improved clinical outcomes. This flexibility is a key feature of the announcement, since it is trying to bring in both basic and applied perspectives to understand the nutrition-alcohol relationship across different settings, outcomes, and biological systems.
The funding mechanism used is the NIH Exploratory/Developmental Research Grant (R21). R21 awards are typically used to support innovative, high-impact concepts and pilot work that can generate preliminary data, prove feasibility, or open up new lines of inquiry that may later grow into larger projects. This R21 announcement runs in parallel with companion announcements of the same scientific scope that accept applications under other mechanisms: PA-07-403 (R01) and PA-07-404 (R03). In other words, NIH is supporting the same research theme through multiple grant types, with the R21 specifically aimed at earlier-stage, developmental projects.
On budget and award size, the announcement sets an Award Ceiling of $200,000, and it emphasizes that the final size and duration of awards can vary depending on the proposed project. NIH does not commit to a fixed number of awards here; instead, the total number funded and the total dollars awarded depend on the volume of submissions, their scientific quality, their proposed duration, and their costs. There is no cost sharing or matching requirement.
Eligibility is broad and includes many organization types. Eligible applicants include public and private institutions of higher education, nonprofits (both with and without 501(c)(3) status), state and local governments (including counties, cities/townships, special districts, and independent school districts), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, small businesses, and for-profit organizations (other than small businesses), with additional eligibility clarified in the full announcement. The FOA explicitly states that foreign institutions are eligible to apply, eligible federal agencies may apply, and faith-based or community-based organizations may also apply, which expands the potential applicant pool beyond typical academic settings.
Administratively, the opportunity was posted July 16, 2007, and uses multiple receipt dates rather than a single deadline, meaning applications are accepted on recurring submission cycles (applicants must refer to the full announcement for the specific dates). The archive date is October 8, 2010, which indicates the FOA is historical/archived rather than an active current solicitation, but it remains a useful reference point for NIH priorities and for locating related or successor announcements.
For full details, including submission instructions and any NIH-specific requirements tied to the R21 mechanism, the announcement directs applicants to the official NIH Grants Guide posting at http://grants.nih.gov/grants/guide/pa-files/PA-07-405.html. The contact listed for technical access and linking problems is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Nutrition and Alcohol Related Health Outcomes (R21) - PA-07-405
What is the Nutrition and Alcohol Related Health Outcomes (R21) opportunity?
It is an NIH discretionary grant opportunity (Funding Opportunity Number PA-07-405) that supports exploratory, early-stage research on how nutrition influences alcohol-related health outcomes. It uses the NIH Exploratory/Developmental Research Grant (R21) mechanism.
Which agencies sponsor PA-07-405?
The opportunity is sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and the NIH Office of Dietary Supplements (ODS).
What is the main purpose of this FOA?
The goal is to stimulate a wide range of studies that clarify whether and how dietary factors, nutrient status, or nutritional interventions affect the development, prevention, or treatment of health problems linked to alcohol use.
What kinds of outcomes or conditions are in scope?
The scope includes a broad set of alcohol-related outcomes, such as alcohol dependence and related behavioral or psychiatric co-morbidities, as well as chronic and acute disease processes and how alcohol affects organ function, injury, and recovery.
What kinds of nutrition-related factors can be studied under this announcement?
The FOA highlights dietary factors, nutrient status, and nutritional interventions. Examples mentioned include nutrient deficiencies, dietary patterns, and targeted supplementation or dietary interventions in the context of alcohol-related health effects.
Are both human and animal model studies allowed?
Yes. The announcement explicitly notes that the research can span both human and animal model work, including biomedical and mechanistic studies.
What study designs does this FOA support?
The FOA is intentionally flexible and allows multiple approaches, including biomedical and mechanistic studies (including animal models), epidemiologic analyses examining diet and alcohol exposure in populations, and intervention studies testing nutritional strategies for prevention or improved clinical outcomes.
Is this funding intended for early-stage or pilot work?
Yes. Because it uses the R21 mechanism, it is aimed at innovative, high-impact concepts and exploratory/developmental projects that can generate preliminary data, demonstrate feasibility, or open new lines of inquiry.
What is the maximum award amount (award ceiling) for PA-07-405?
The announcement lists an award ceiling of $200,000.
Are award size and duration fixed?
No. The FOA emphasizes that the final size and duration of awards can vary depending on the proposed project.
Does NIH guarantee a specific number of awards under this FOA?
No. NIH does not commit to a fixed number of awards. The number funded and total dollars awarded depend on factors such as submission volume, scientific quality, proposed duration, and costs.
Is there a cost sharing or matching requirement?
No. The FOA states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many organization types, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), state and local governments (including counties, cities/townships, special districts, and independent school districts), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, small businesses, and for-profit organizations (other than small businesses), with additional eligibility clarified in the full announcement.
Are foreign institutions eligible to apply?
Yes. The FOA explicitly states that foreign institutions are eligible to apply.
Can federal agencies apply?
Yes. The FOA states that eligible federal agencies may apply.
Are faith-based or community-based organizations allowed to apply?
Yes. The FOA explicitly notes that faith-based or community-based organizations may apply.
When was this funding opportunity posted?
The opportunity was posted on July 16, 2007.
Is there a single deadline or multiple receipt dates?
The FOA uses multiple receipt dates rather than a single deadline, meaning applications are accepted on recurring submission cycles. Applicants are directed to the full announcement for the specific receipt dates.
Is PA-07-405 still active?
The archive date is October 8, 2010, indicating the FOA is historical/archived rather than an active current solicitation. It may still be useful as a reference point for NIH priorities and for locating related or successor announcements.
Are there related announcements for the same scientific scope under other mechanisms?
Yes. This R21 announcement runs in parallel with companion announcements addressing the same theme under other mechanisms: PA-07-403 (R01) and PA-07-404 (R03).
Where can applicants find the official FOA text and full instructions?
The FOA directs applicants to the NIH Grants Guide posting at http://grants.nih.gov/grants/guide/pa-files/PA-07-405.html for full details, including submission instructions and any NIH-specific requirements tied to the R21 mechanism.
Who should be contacted for technical access or linking problems with the FOA webpage?
The contact listed for technical access and linking problems is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 07 405) also looked into and applied for these:
| Funding Opportunity |
|---|
| Short Term Career Development Award in the Environmental Health Sciences for Established Investigators (K18) Apply for PAR 07 402 Funding Number: PAR 07 402 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Research to Action Assessing and Addressing Community Exposures to Environmental Contaminants (R21) Apply for RFA ES 09 001 Funding Number: RFA ES 09 001 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Environmental Health Sciences Core Center Grants (P30) Apply for RFA ES 09 002 Funding Number: RFA ES 09 002 Agency: National Institutes of Health Category: Environment Health Funding Amount: $500,000 |
| Childrens Environmental Health and Disease Prevention Research Centers (P01) Apply for RFA ES 08 002 Funding Number: RFA ES 08 002 Agency: National Institutes of Health Category: Environment Health Funding Amount: $900,000 |
| Childrens Environmental Health and Disease Prevention Research Centers Formative Centers (P20) Apply for RFA ES 08 004 Funding Number: RFA ES 08 004 Agency: National Institutes of Health Category: Environment Health Funding Amount: $500,000 |
| Short Term Career Development Award in the Environmental Health Sciences for Established Investigators (K18) Apply for PAR 09 090 Funding Number: PAR 09 090 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Environmental Sensors for Personal Exposure Assessment(SBIR R44) Apply for RFA ES 09 005 Funding Number: RFA ES 09 005 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| SBIR E learning for HAZMAT and Emergency Response (SBIR R43/R44) Apply for RFA ES 09 006 Funding Number: RFA ES 09 006 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Hazardous Materials Worker Health and Safety Training (U45) Apply for RFA ES 09 004 Funding Number: RFA ES 09 004 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Hazmat Training at Doe Nuclear Weapons Complex (U45) Apply for RFA ES 09 003 Funding Number: RFA ES 09 003 Agency: National Institutes of Health Category: Environment Health Funding Amount: $700,000 |
| Outstanding New Environmental Scientist Award (ONES) (R01) Apply for RFA ES 09 007 Funding Number: RFA ES 09 007 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Countermeasures Against Chemical Threats (CounterACT) Exploratory/Developmental Projects in Translational Research (R21) Apply for PAR 10 019 Funding Number: PAR 10 019 Agency: National Institutes of Health Category: Environment Health Funding Amount: $250,000 |
| Engineered Nanomaterials Linking Physical and Chemical Properties to Biology (U19) Apply for RFA ES 09 011 Funding Number: RFA ES 09 011 Agency: National Institutes of Health Category: Environment Health Funding Amount: $750,000 |
| Limited Competition NIH Competitive Revision Awards for Creating Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01) Apply for PAR 10 030 Funding Number: PAR 10 030 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Mechanism for Time Sensitive Research Opportunities in Environmental Health Sciences (R03) Apply for PAR 10 083 Funding Number: PAR 10 083 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Mechanism for Time Sensitive Research Opportunities in Environmental Health Sciences (R21) Apply for PAR 10 084 Funding Number: PAR 10 084 Agency: National Institutes of Health Category: Environment Health Funding Amount: $200,000 |
| Parkinsons Disease Data Organizing Center PD DOC (U24) Apply for RFA NS 11 001 Funding Number: RFA NS 11 001 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Outstanding New Environmental Scientist Award (ONES) (R01) Apply for RFA ES 10 004 Funding Number: RFA ES 10 004 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| SBIR E learning for HAZMAT and Emergency Response (SBIR R43/R44) Apply for RFA ES 10 003 Funding Number: RFA ES 10 003 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Neurobiology of Migraine (R21) Apply for PA 10 259 Funding Number: PA 10 259 Agency: National Institutes of Health Category: Environment Health Funding Amount: $200,000 |
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