Opportunity Information: Apply for W81XWH 09 OETRP

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Orthopaedic Extremity Trauma Research Program" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on May 11, 2009 and posted on Mar 20, 2009.
  • Applicants must submit their applications by May 15, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $14,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 09 OETRP

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Opportunity Summary:

The Orthopaedic Extremity Trauma Research Program (OETRP) is a Department of the Army funding opportunity focused on improving clinical care for extremity injuries that are relevant to military operations. The program is specifically looking for proposals that will run prospective, multi-center clinical trials, with randomization of treatments strongly preferred whenever it is feasible and ethically appropriate. The intent is to generate high-quality evidence that can directly inform practice for the kinds of complex limb injuries seen in service members, including those treated in military treatment facilities.

A central feature of this announcement is that it plans to fund a single, large consortium rather than multiple independent projects. The consortium is expected to include enough participating clinical sites and sufficient patient volume to reliably enroll participants and complete rigorous clinical trials. Because the research must be military-relevant, proposals need to clearly connect the study questions, patient population, injury mechanisms, and care pathways to military extremity trauma. In practical terms, this means the research cannot be purely civilian in scope; cooperation with, and inclusion of, capable military hospitals is described as a requirement, not an optional partnership element.

The award mechanism is expected to be a cooperative agreement, which signals that the government will have substantial involvement during the project rather than acting only as a passive funder. In this case, the US Army Institute of Surgical Research (USAISR) is designated to serve as the technical lead. The funded consortium would work in partnership with USAISR to help set research priorities and execute the studies. The announcement also notes that study designs and specific studies may be modified after award, reflecting a more adaptive, collaborative approach where protocols, trial selection, and operational details can be refined as the partnership develops and as emerging needs or feasibility considerations become clearer.

From an administrative and funding standpoint, the opportunity is listed under Funding Opportunity Number W81XWH-09-OETRP and falls under the science and technology / research and development activity category. The agency is the Department of the Army through USAMRAA, and the associated CFDA program number is 12.420 (Military Medical Research and Development). The anticipated total funding is approximately $14,000,000, with an expectation of one award. There is no cost-sharing or matching requirement stated. Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional clarifications in the full announcement.

Key dates provided in the announcement include a posted date of March 20, 2009, an original closing date of May 1, 2009, and a revised/current closing date of May 15, 2009, with an archive date of May 31, 2009. For applicants who have trouble accessing the full announcement electronically, the listed contact is Kathryn McCune, Contract Specialist, reachable by phone at 301-619-1354, identified as the OETRP point of contact.

Orthopaedic Extremity Trauma Research Program (OETRP) FAQs

1) What is the Orthopaedic Extremity Trauma Research Program (OETRP)?

The Orthopaedic Extremity Trauma Research Program (OETRP) is a Department of the Army funding opportunity focused on improving clinical care for extremity injuries that are relevant to military operations. The intent is to generate high-quality clinical evidence that can directly inform practice for complex limb injuries seen in service members, including those treated in military treatment facilities.

2) What types of studies is OETRP specifically looking to fund?

The program is specifically looking for proposals that will run prospective, multi-center clinical trials. Randomization of treatments is strongly preferred whenever it is feasible and ethically appropriate.

3) Are randomized clinical trials required?

Randomization is strongly preferred when feasible and ethically appropriate, but the announcement does not state it is an absolute requirement in all situations.

4) Does the opportunity prioritize multi-center trials?

Yes. The announcement emphasizes prospective, multi-center clinical trials and expects the consortium to include enough participating clinical sites and sufficient patient volume to reliably enroll participants and complete rigorous clinical trials.

5) Is this opportunity funding multiple separate projects or one coordinated effort?

A central feature of the announcement is the plan to fund a single, large consortium rather than multiple independent projects. The expectation is one award.

6) What is meant by a "consortium" in this announcement?

Based on the description provided, the consortium is a coordinated network of participating clinical sites designed to collectively provide adequate patient volume and operational capability to enroll participants and conduct rigorous multi-center clinical trials.

7) What does "military-relevant" research mean for this program?

Proposals need to clearly connect the study questions, patient population, injury mechanisms, and care pathways to military extremity trauma. The research cannot be purely civilian in scope.

8) Are military hospitals required to be involved?

Yes. Cooperation with, and inclusion of, capable military hospitals is described as a requirement, not an optional partnership element.

9) Can a proposal be conducted entirely in civilian hospitals?

No. The announcement indicates the work cannot be purely civilian in scope and requires cooperation with and inclusion of capable military hospitals.

10) What award mechanism is expected for this opportunity?

The award mechanism is expected to be a cooperative agreement, meaning the government will have substantial involvement during the project rather than acting only as a passive funder.

11) Which organization will serve as the technical lead for the government?

The US Army Institute of Surgical Research (USAISR) is designated to serve as the technical lead.

12) How will the funded consortium work with USAISR?

The funded consortium is expected to work in partnership with USAISR to help set research priorities and execute the studies.

13) Can the study designs or chosen studies change after an award is made?

Yes. The announcement notes that study designs and specific studies may be modified after award, reflecting an adaptive, collaborative approach where protocols, trial selection, and operational details can be refined as the partnership develops and as emerging needs or feasibility considerations become clearer.

14) What is the Funding Opportunity Number (FON) for this announcement?

The Funding Opportunity Number is W81XWH-09-OETRP.

15) Which agency is offering this funding opportunity?

The agency is the Department of the Army through USAMRAA.

16) What activity category does this opportunity fall under?

The opportunity falls under the science and technology / research and development activity category.

17) What is the CFDA program number associated with this opportunity?

The associated CFDA program number is 12.420 (Military Medical Research and Development).

18) How much total funding is anticipated?

The anticipated total funding is approximately $14,000,000.

19) How many awards are expected?

The announcement indicates an expectation of one award.

20) Is cost sharing or matching required?

No cost-sharing or matching requirement is stated in the information provided.

21) Who is eligible to apply?

Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional clarifications in the full announcement.

22) What are the key dates for this opportunity?

Posted date: March 20, 2009
Original closing date: May 1, 2009
Revised/current closing date: May 15, 2009
Archive date: May 31, 2009

23) What is the current closing date applicants should follow?

The revised/current closing date listed is May 15, 2009.

24) Who should applicants contact if they cannot access the full announcement electronically?

Applicants who have trouble accessing the full announcement electronically are directed to contact Kathryn McCune, Contract Specialist, identified as the OETRP point of contact.

25) What contact details are provided for the OETRP point of contact?

Kathryn McCune, Contract Specialist, phone: 301-619-1354.

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