Opportunity Information: Apply for RFA NS 11 001
Apply for RFA NS 11 001
- The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Parkinsons Disease Data Organizing Center PD DOC (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Jan 21, 2010 and posted on Jan 21, 2010.
- Applicants must submit their applications by Apr 30, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Independent school districts Private institutions of higher education Public housing authorities/Indian housing authorities Small businesses Native American tribal governments (Federally recognized) City or township governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) State governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education County governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Parkinsons Disease Data Organizing Center (PD-DOC) (U24) funding opportunity (RFA-NS-11-001) is a cooperative agreement offered by the National Institutes of Health, led by the National Institute of Neurological Disorders and Stroke (NINDS) in partnership with the National Institute of Environmental Health Sciences (NIEHS). Its main aim is to support the redesign and enhancement of a centralized, community-facing data organizing center for Parkinsons disease research. The program is built around a clear need in the field: making clinical and translational Parkinsons data easier to collect, standardize, connect, and share so it can be reused to accelerate discovery and improve future studies.
At the core of the grant is the creation and ongoing operation of a robust repository for Parkinsons disease data drawn from clinical trials and clinical studies. This includes not only traditional clinical datasets, but also data from epidemiologic and genetic studies and other PD-relevant clinical research efforts. The announcement emphasizes that the repository should be able to accommodate multiple data types, including clinical measures as well as related imaging, genetic, and neuropathology data elements. A major value-add is that the PD-DOC is expected to connect or link clinical datasets with associated information stored elsewhere, such as genetic data, biospecimen information, imaging collections, and neuropathology resources when those are housed in other databases. In practice, that means the center is expected to do more than simply store files; it should help researchers navigate and integrate related data streams so that PD studies can be analyzed more comprehensively.
Another major deliverable is a flexible, web-based data entry system designed for Parkinsons clinical research. The FOA calls for this system to use standardized common data elements (CDEs) suitable for PD studies, while still being adaptable so investigators can modify it for different study designs and protocols. The intent is to lower the friction of data capture across many projects by encouraging consistent data structure and terminology, while still allowing enough flexibility to support the real-world diversity of PD clinical research. This focus on standardization is tied directly to the broader goal of data reuse: the more consistently data are collected, the easier it becomes to combine or compare datasets across studies.
Beyond data intake and storage, the PD-DOC is also expected to function as an active, visible resource for the broader scientific community. The center should maintain an up-to-date listing of relevant research resources for PD investigators, effectively serving as a hub where researchers can find data-related tools and assets. The FOA also highlights the importance of ongoing outreach to maximize participation and data sharing. This means the awardee should not treat the repository as a passive archive; they are expected to engage the PD research community, encourage deposition and use of data, and help ensure the resource becomes widely adopted. Underlying all of this is an expectation that the information technology approach will prioritize accessibility and usefulness, so that researchers can actually find, understand, and work with the information efficiently.
From an administrative standpoint, this opportunity is a discretionary NIH cooperative agreement (U24), meaning NIH program staff will have substantial involvement in shaping or overseeing the project compared with a standard grant mechanism. The estimated total funding listed is $6,000,000. The opportunity was posted January 21, 2010, with an original and current closing date of April 30, 2010, and it was archived May 31, 2010. There is no cost sharing or matching requirement noted.
Eligibility is broad and includes many organization types across academia, government, nonprofit, and industry. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), independent school districts, and a wide range of government entities such as state, county, city/township, special district governments, and certain housing authorities. The eligibility language also explicitly includes a variety of historically underrepresented or special-designation institutions and entities, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, tribal governments and tribal organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
In plain terms, this FOA is about building and running a modern, researcher-friendly Parkinsons disease data hub: one that can take in data from many kinds of PD studies, standardize and connect those data to related resources, provide a configurable web-based data entry platform using common data elements, keep the community informed about available resources, and actively promote sharing and reuse so the entire PD research ecosystem benefits.
Frequently Asked Questions (FAQs): Parkinsons Disease Data Organizing Center (PD-DOC) (U24) - RFA-NS-11-001
What is the PD-DOC (U24) funding opportunity?
The Parkinsons Disease Data Organizing Center (PD-DOC) (U24) opportunity (RFA-NS-11-001) is an NIH cooperative agreement intended to support the redesign, enhancement, and ongoing operation of a centralized, community-facing data organizing center for Parkinsons disease research.
Which agencies are sponsoring and leading this opportunity?
This opportunity is offered by the National Institutes of Health (NIH), led by the National Institute of Neurological Disorders and Stroke (NINDS) in partnership with the National Institute of Environmental Health Sciences (NIEHS).
What is the main purpose of this FOA?
The main purpose is to make Parkinsons disease clinical and translational research data easier to collect, standardize, connect, share, and reuse, so the field can accelerate discovery and improve future studies.
What type of award mechanism is used?
The mechanism is a discretionary NIH cooperative agreement (U24), which means NIH program staff will have substantial involvement in shaping and/or overseeing the project compared with a standard grant.
What are the core deliverables expected from the PD-DOC?
Key deliverables include: (1) a robust repository for Parkinsons disease data from clinical trials and clinical studies (including additional PD-relevant clinical research), (2) a flexible, web-based data entry system for PD clinical research that uses standardized common data elements (CDEs) while remaining adaptable for different study designs, and (3) an active community-facing hub with resource listings and outreach to increase participation and data sharing.
What kinds of studies and data should the repository support?
The repository is expected to support Parkinsons disease data drawn from clinical trials and clinical studies, and it also includes data from epidemiologic studies, genetic studies, and other PD-relevant clinical research efforts.
What data types should the PD-DOC be able to accommodate?
The FOA emphasizes accommodating multiple data types, including clinical measures and related imaging, genetic, and neuropathology data elements.
Is the PD-DOC expected to do more than store datasets?
Yes. The center is expected to help connect or link clinical datasets with associated information stored elsewhere, such as genetic data, biospecimen information, imaging collections, and neuropathology resources when those are housed in other databases.
What does "linking" datasets to other resources mean in this FOA?
In practical terms, it means the PD-DOC should support researchers in navigating and integrating related data streams (for example, connecting clinical datasets to external genetic or imaging resources) so analyses can be more comprehensive than working with isolated files.
What is the web-based data entry system expected to do?
The FOA calls for a flexible, web-based data entry system designed for Parkinsons clinical research that encourages consistent data capture across projects while allowing investigators to modify it for different study designs and protocols.
What are Common Data Elements (CDEs) in the context of this opportunity?
In this FOA, CDEs refer to standardized data elements suitable for Parkinsons disease studies, used to promote consistent structure and terminology so that datasets can be compared, combined, and reused more easily across studies.
Why is standardization emphasized so heavily?
The opportunity ties standardization directly to data reuse: when data are collected in consistent formats with consistent terminology, it becomes easier to combine or compare datasets across different studies, supporting broader discovery and more efficient future research.
How is the PD-DOC expected to serve the broader research community?
The center is expected to function as a visible resource for the PD scientific community by maintaining an up-to-date listing of relevant research resources for PD investigators and by prioritizing accessibility and usefulness so researchers can find, understand, and work with the information efficiently.
Is outreach and community engagement part of the required work?
Yes. The FOA highlights ongoing outreach to maximize participation and data sharing, with the expectation that the repository will be actively promoted and widely adopted rather than treated as a passive archive.
How much total funding is listed for this opportunity?
The estimated total funding listed is $6,000,000.
Is cost sharing or matching required?
No cost sharing or matching requirement is noted in the provided opportunity information.
When was this funding opportunity posted, and what were the closing dates?
The opportunity was posted on January 21, 2010. The original closing date and the current closing date are both listed as April 30, 2010.
What does it mean that the opportunity is archived?
The information indicates the opportunity was archived on May 31, 2010, meaning it is no longer active as a current open solicitation based on the dates provided.
Who is eligible to apply?
Eligibility is broad and includes many organization types across academia, government, nonprofit, and industry, including public and private institutions of higher education, nonprofits (with and without 501(c)(3) status), for-profit organizations (including small businesses), independent school districts, and many types of government entities.
Are state and local government entities eligible?
Yes. The eligibility language includes state governments, county governments, city or township governments, special district governments, and certain housing authorities.
Are tribal entities and tribal-serving institutions included in eligibility?
Yes. The eligibility description explicitly includes tribally controlled colleges and universities, tribal governments, and tribal organizations.
Are historically underrepresented or special-designation institutions explicitly included?
Yes. The eligibility language explicitly includes entities such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, and other similarly designated institutions described in the eligibility list.
Can U.S. territories or possessions apply?
Yes. The eligibility list includes U.S. territories or possessions.
What is the overall plain-language summary of what this FOA is trying to build?
In plain terms, this FOA is about building and running a modern, researcher-friendly Parkinsons disease data hub that can take in data from many PD studies, standardize and connect those data to related resources, provide a configurable web-based data entry platform using common data elements, keep the community informed about available tools and assets, and actively promote sharing and reuse across the PD research ecosystem.
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