Opportunity Information: Apply for RFA HL 11 027
Apply for RFA HL 11 027
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Pediatric Heart Network (U10) Limited Competition for the Data Coordinating Center" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research.
- This funding opportunity was created on Jul 19, 2010 and posted on Jul 19, 2010.
- Applicants must submit their applications by Oct 29, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $400,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Only the current PHN Data Coordinating Center awardee institution is eligible to apply in response to this FOA.
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Opportunity Summary:
The Pediatric Heart Network (PHN) (U10) Limited Competition for the Data Coordinating Center is a National Institutes of Health (NIH) cooperative agreement opportunity designed specifically to continue support for the PHN Data Coordinating Center (DCC). The PHN is a long-running multicenter clinical research network focused on improving health outcomes and quality of life for children, adolescents, and young adults living with congenital or acquired heart disease. The overall aim of the network is to make pediatric and congenital cardiovascular care more evidence-based by enabling rigorous, collaborative studies that can evaluate medical, interventional, and surgical therapies across multiple institutions rather than relying on single-center experience.
This particular funding opportunity announcement (FOA) is a limited competition renewal, meaning it is not open to new institutions or general applicants. Only the institution that is currently funded as the PHN Data Coordinating Center is eligible to apply. The rationale is continuity: the DCC functions as the operational and analytic hub of the entire network, supporting the PHN Clinical Centers (which are competed under a separate FOA) and ensuring that network-wide studies are designed, managed, analyzed, and reported in a consistent and high-quality manner. In practical terms, the DCC is central to making multicenter clinical research work at scale, including coordinating protocols, data systems, quality control, and cross-site collaboration.
The mission and scope of the PHN, as described in the announcement, emphasize evaluating therapeutic and management strategies for several major pediatric and congenital cardiovascular populations. These include children and adults with congenital heart defects, as well as children affected by inflammatory heart disease, heart muscle disease (cardiomyopathies), and arrhythmias. By supporting a network infrastructure, the PHN is positioned to run studies that require larger, diverse patient cohorts and standardized methods, which are often essential in pediatric cardiology where individual centers may see relatively small numbers of specific conditions.
Beyond running studies, the PHN is also framed as a professional development and dissemination platform. The network is intended to serve as a training environment for fellows, junior faculty, and nurses who are building expertise in clinical research methods and multicenter trial operations. It also places explicit emphasis on dissemination of study results so that findings translate into improved clinical practice and a stronger scientific foundation for caring for patients with complex heart disease beginning in childhood and extending into young adulthood.
Mechanistically, the award uses the U10 cooperative agreement model. A cooperative agreement indicates that NIH will have substantial programmatic involvement compared with a standard research grant, reflecting the coordinated, network-based nature of the work. The activity falls under the Health category and is associated with CFDA 93.837 (Cardiovascular Diseases Research). The funding instrument type is a cooperative agreement, and there is no cost sharing or matching requirement noted in the announcement.
Key administrative details include the FOA number RFA-HL-11-027, posted July 19, 2010, with an original and current closing date of October 29, 2010, and an archive date of November 29, 2010. The listed award ceiling is $400,000. The eligible applicant type is specified as public and state-controlled institutions of higher education, but the eligibility is effectively narrowed to a single applicant: only the current PHN DCC awardee institution may submit an application in response to this limited competition renewal.
For additional details, NIH provided an online link to the full FOA text, and included contact guidance through the NIH Office of Extramural Research (OER) Webmaster for technical issues accessing or linking to the announcement.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the Pediatric Heart Network (PHN) (U10) Limited Competition for the Data Coordinating Center (DCC), a National Institutes of Health (NIH) cooperative agreement intended to continue support for the PHN Data Coordinating Center.
What is the FOA number for this opportunity?
The Funding Opportunity Announcement (FOA) number is RFA-HL-11-027.
Who is the sponsor or issuing agency?
The opportunity is issued by the National Institutes of Health (NIH).
What does "limited competition renewal" mean here?
"Limited competition renewal" means the opportunity is not open to new institutions or the general applicant pool. It is a renewal competition restricted to a specific eligible applicant (the currently funded PHN Data Coordinating Center).
Who is eligible to apply?
Eligibility is effectively limited to one institution: only the institution that is currently funded as the PHN Data Coordinating Center (DCC) may submit an application under this announcement. While the eligible applicant type is listed as public and state-controlled institutions of higher education, the limited competition restriction narrows eligibility to the current DCC awardee institution.
Can a new institution apply to become the PHN Data Coordinating Center under this FOA?
No. This FOA is not open to new institutions. Only the current PHN DCC awardee institution is eligible to apply.
What is the Pediatric Heart Network (PHN)?
The PHN is a long-running multicenter clinical research network focused on improving health outcomes and quality of life for children, adolescents, and young adults with congenital or acquired heart disease. It is designed to make pediatric and congenital cardiovascular care more evidence-based by enabling rigorous, collaborative studies across multiple institutions.
What is the overall aim of the PHN?
The network aims to support evidence-based pediatric and congenital cardiovascular care by enabling multicenter studies that can evaluate medical, interventional, and surgical therapies using standardized methods and larger, more diverse patient cohorts than single-center studies typically allow.
What populations and conditions are emphasized in the PHN scope?
The PHN scope emphasizes therapeutic and management strategies for major pediatric and congenital cardiovascular populations, including children and adults with congenital heart defects, and children affected by inflammatory heart disease, cardiomyopathies (heart muscle disease), and arrhythmias.
What is the role of the Data Coordinating Center (DCC) in the PHN?
The DCC serves as the operational and analytic hub for the entire network. It supports the PHN Clinical Centers (which are competed under a separate FOA) and helps ensure that network-wide studies are designed, managed, analyzed, and reported in a consistent and high-quality way.
What kinds of activities does the DCC typically support for multicenter research?
Based on the announcement description, the DCC is central to making multicenter research work at scale by coordinating protocols, data systems, quality control, and cross-site collaboration, and by supporting consistent study design, management, analysis, and reporting across the network.
Is this opportunity meant to fund PHN Clinical Centers?
No. This announcement is specifically for the PHN Data Coordinating Center (DCC). The PHN Clinical Centers are competed under a separate FOA.
What is the funding mechanism used for this award?
The award uses the U10 cooperative agreement mechanism.
What does a cooperative agreement imply for NIH involvement?
A cooperative agreement indicates that NIH will have substantial programmatic involvement compared with a standard research grant, reflecting the coordinated and network-based nature of the work.
What is the program category and CFDA number?
The activity falls under the Health category and is associated with CFDA 93.837 (Cardiovascular Diseases Research).
Is cost sharing or matching required?
No cost sharing or matching requirement is noted in the announcement.
What is the award ceiling listed for this opportunity?
The listed award ceiling is $400,000.
When was the FOA posted?
The FOA was posted on July 19, 2010.
What are the closing dates listed for this FOA?
The original closing date and the current closing date are both listed as October 29, 2010.
What is the archive date for this FOA?
The archive date is listed as November 29, 2010.
Why is the DCC renewal restricted to the current awardee?
The stated rationale is continuity. Because the DCC functions as the operational and analytic hub of the entire network, continuity helps maintain consistent network-wide study design, coordination, data quality, analysis, and reporting.
Does the PHN have goals beyond conducting studies?
Yes. The PHN is also framed as a professional development and dissemination platform, intended to support training for fellows, junior faculty, and nurses in clinical research methods and multicenter trial operations, and to emphasize dissemination of study results to strengthen clinical practice.
Where can applicants or readers find the full FOA text?
NIH provided an online link to the full FOA text in the announcement materials.
Who should be contacted for technical issues accessing or linking to the FOA?
The announcement includes contact guidance through the NIH Office of Extramural Research (OER) Webmaster for technical issues related to accessing or linking to the FOA.
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