Opportunity Information: Apply for PA 09 081

  • The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "PHS 2009 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.173 Research Related to Deafness and Communication Disorders 93.184 Disabilities Prevention 93.185 Immunization Research, Demonstration, Public Information and EducationTraining and Clinical Skills Improvement Projects 93.197 Childhood Lead Poisoning Prevention ProjectsState and Local Childhood Lead Poisoning Prevention and Surveillance of Blo 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.389 National Center for Research Resources 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
  • This funding opportunity was created on Jan 22, 2009 and posted on Jan 22, 2009.
  • Applicants must submit their applications by Jan 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: Small businesses.
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Opportunity Summary:

The PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer (STTR) Grant Applications (Parent STTR R41/R42), Funding Opportunity Number PA-09-081, is a National Institutes of Health (NIH) grant opportunity designed to help U.S. small business concerns move early-stage biomedical and behavioral innovations toward practical, real-world use. The core aim is to support research and development that aligns with the missions of participating NIH Institutes and Centers, with projects proposed in response to NIH’s published SBIR/STTR program descriptions and research topics for that solicitation cycle. In plain terms, NIH is looking for small companies that have strong technical capabilities and can work hand-in-hand with a nonprofit research institution to translate promising ideas into technologies, tools, or interventions that improve human health.

This announcement uses the STTR mechanism, which is specifically built around formal collaboration between a small business and a U.S. research institution. The grant mechanisms supported under this FOA are R41 (Phase I), R42 (Phase II), and Fast-Track applications that combine Phase I and Phase II into a single, continuous submission. Phase I funding is generally meant to establish feasibility and produce proof-of-concept results, while Phase II supports more advanced R&D efforts such as refinement, validation, scaling, and preparation for commercialization or broader implementation. A key point in the solicitation is that STTR applications under this program are accepted only by NIH; other HHS agencies that sometimes participate in related programs (specifically the CDC, FDA, and ACF) do not take part in the STTR program under this announcement.

The opportunity is categorized as discretionary grant funding and is tied to a wide range of NIH-related research and public health areas. The CFDA program numbers listed span many scientific domains, including environmental health, deafness and communication disorders, disability prevention, immunization research and education, childhood lead poisoning prevention, sleep disorders research, mental health, minority health and health disparities, nursing research, research infrastructure, and a broad spectrum of disease-focused areas. These include cancer (cause and prevention, detection and diagnosis, treatment, biology, and control), cardiovascular disease, lung disease, blood diseases, arthritis and musculoskeletal conditions, diabetes and digestive and kidney diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, infectious diseases, general biomedical research and training, child health and human development, aging, vision research, and medical library assistance. The breadth of CFDA listings signals that NIH intended this parent solicitation to be broadly usable across many Institutes and Centers, as long as the proposed STTR work fit the relevant NIH mission and the specific topic areas referenced for that year’s omnibus solicitation.

Eligibility is limited to small businesses in the United States, consistent with STTR program requirements. There is no stated cost-sharing or matching requirement, which means applicants are not required to provide non-federal matching funds as a condition of receiving the award. The grant opportunity was posted and created on January 22, 2009, with an original and current closing date of January 7, 2010, and an archive date of February 7, 2010, indicating the solicitation was time-limited and is now closed. The summary data also lists an award ceiling of $100,000, which typically reflects a cap for certain components or a summarized limit in the source listing, though actual NIH STTR award budgets can vary by phase, institute policies, and justification within NIH guidelines.

Administratively, the FOA is positioned as a companion to a parallel NIH solicitation with the same scientific scope for the Small Business Innovation Research (SBIR) program, PA-09-080, which uses different grant mechanisms (R43/R44). The distinction matters because SBIR and STTR differ in collaboration requirements and how the research effort is allocated between the company and the partnering research institution. This FOA is specifically for STTR (R41/R42), meaning the collaboration element is central rather than optional. For applicants needing the complete official details, NIH provided an additional information link to the full FOA text on the NIH Grants Guide website, and included contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

FAQs: NIH STTR Omnibus Solicitation (Parent STTR R41/R42) - PA-09-081 (PHS 2009-02)

What is this funding opportunity?

This opportunity is the PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer (STTR) Grant Applications (Parent STTR R41/R42), Funding Opportunity Number PA-09-081. It is an NIH grant opportunity intended to help U.S. small business concerns move early-stage biomedical and behavioral innovations toward practical, real-world use through research and development aligned with participating NIH Institutes and Centers.

What is the main purpose of PA-09-081?

The core aim is to support R&D projects that fit the missions of participating NIH Institutes and Centers and respond to the NIH SBIR/STTR program descriptions and research topics for that omnibus solicitation cycle. In practical terms, NIH is seeking small companies with strong technical capabilities that can collaborate formally with a U.S. nonprofit research institution to translate promising ideas into technologies, tools, or interventions that improve human health.

Which organization is offering and accepting applications for this opportunity?

Applications under this announcement are accepted only by the National Institutes of Health (NIH). The solicitation notes that other HHS agencies sometimes involved in related programs (CDC, FDA, and ACF) do not participate in the STTR program under this announcement.

What type of funding is this?

It is categorized as discretionary grant funding under the NIH STTR program.

What grant mechanisms (award types) are supported?

This FOA supports the STTR mechanisms R41 (Phase I), R42 (Phase II), and Fast-Track applications that combine Phase I and Phase II into a single, continuous submission.

What is the difference between Phase I (R41) and Phase II (R42) in this announcement?

Phase I (R41) is generally intended to establish feasibility and generate proof-of-concept results. Phase II (R42) supports more advanced R&D such as refinement, validation, scaling, and preparation for commercialization or broader implementation.

What is a Fast-Track application under this FOA?

A Fast-Track application combines Phase I and Phase II into one submission intended to support a continuous progression from feasibility/proof-of-concept work into more advanced development.

Who is eligible to apply?

Eligibility is limited to small businesses in the United States, consistent with STTR program requirements.

Is a research institution partner required?

Yes. The STTR mechanism described in the announcement is specifically built around a formal collaboration between a small business and a U.S. research institution, and the collaboration element is described as central to this FOA.

How is this STTR opportunity different from the related SBIR opportunity mentioned?

This FOA is the companion to a parallel NIH solicitation with the same scientific scope for SBIR, PA-09-080, which uses different mechanisms (R43/R44). The distinction highlighted is that SBIR and STTR differ in collaboration requirements and how the research effort is allocated between the company and the partnering research institution, and this FOA is specifically for STTR (R41/R42) where collaboration is central rather than optional.

What research areas or topics does this funding opportunity cover?

The solicitation is broadly usable across many NIH Institutes and Centers as long as the proposed STTR work fits the relevant NIH mission and the specific topic areas referenced for that year’s omnibus solicitation. The CFDA program numbers listed span many scientific and public health domains, including (as examples) environmental health; deafness and communication disorders; disability prevention; immunization research and education; childhood lead poisoning prevention; sleep disorders research; mental health; minority health and health disparities; nursing research; research infrastructure; and a wide range of disease-focused areas (including multiple cancer areas, cardiovascular/lung/blood diseases, musculoskeletal conditions, diabetes/digestive/kidney diseases, neuroscience/neurological disorders, allergy/immunology/transplantation, infectious diseases, child health and human development, aging, vision research, and medical library assistance).

Does the opportunity require cost-sharing or matching funds?

No cost-sharing or matching requirement is stated. Based on the information provided, applicants are not required to provide non-federal matching funds as a condition of receiving an award.

What are the key dates for this solicitation?

The opportunity was posted and created on January 22, 2009. The original and current closing date listed is January 7, 2010, and the archive date is February 7, 2010.

Is this funding opportunity still open?

No. The dates provided indicate it was time-limited and is now closed (closing date January 7, 2010; archive date February 7, 2010).

What is the award ceiling listed for this opportunity?

The summary data lists an award ceiling of $100,000. The information provided also notes this may reflect a cap for certain components or a summarized limit in the source listing, and that actual NIH STTR award budgets can vary by phase, institute policies, and budget justification within NIH guidelines.

Where can applicants find the official full text of the FOA?

NIH provided an additional information link to the full FOA text on the NIH Grants Guide website.

Who is the contact for technical issues accessing the FOA information?

For access or linking issues, the information provided references support through the NIH Office of Extramural Research (OER) webmaster.

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Previous opportunity: PHS 2009 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44)

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Funding Number: PA 10 067
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Funding Number: PA 10 070
Agency: National Institutes of Health
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NIH Support for Conferences and Scientific Meetings (Parent R13/U13) Apply for PA 10 071

Funding Number: PA 10 071
Agency: National Institutes of Health
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PHS 2010 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44) Apply for PA 10 050

Funding Number: PA 10 050
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PHS 2010 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) Apply for PA 10 051

Funding Number: PA 10 051
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health Related Research (Parent F31 Diversity) Apply for PA 10 109

Funding Number: PA 10 109
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (Parent F32) Apply for PA 10 110

Funding Number: PA 10 110
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Understanding and Promoting Health Literacy (R01) Apply for PAR 10 133

Funding Number: PAR 10 133
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R01) Apply for PAR 10 136

Funding Number: PAR 10 136
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Advancing Novel Science in Womens Health Research (ANSWHR) (R21) Apply for PAS 10 226

Funding Number: PAS 10 226
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
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Effects of the Social Environment on Health Measurement, Methods and Mechanisms (R01) Apply for RFA DA 11 003

Funding Number: RFA DA 11 003
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Category: Education Environment Food and Nutrition Health Income Security and Social Services
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Sleep and Social Environment Basic Biopsychosocial Processes (R21) Apply for RFA HD 11 102

Funding Number: RFA HD 11 102
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $200,000
Sleep and Social Environment Basic Biopsychosocial Processes (R01) Apply for RFA HD 11 101

Funding Number: RFA HD 11 101
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Basic Research on Self Regulation (R21) Apply for RFA AG 11 010

Funding Number: RFA AG 11 010
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Psychosocial Stress and Behavior Integration of Behavioral and Physiological Processes (R01) Apply for RFA HL 11 033

Funding Number: RFA HL 11 033
Agency: National Institutes of Health
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Development of Comprehensive and Conceptually based Measures of Psychosocial Stress (R21) Apply for RFA HL 11 034

Funding Number: RFA HL 11 034
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
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Basic Mechanisms Influencing Behavioral Maintenance (R01) Apply for RFA HL 11 035

Funding Number: RFA HL 11 035
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