Opportunity Information: Apply for PA 10 050

  • The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "PHS 2010 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.061 Innovations in Applied Public Health Research 93.103 Food and Drug AdministrationResearch 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.143 NIEHS Superfund Hazardous SubstancesBasic Research and Education 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.262 Occupational Safety and Health Program 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.389 National Center for Research Resources 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.647 Social Services Research and Demonstration 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
  • This funding opportunity was created on Jan 15, 2010 and posted on Jan 15, 2010.
  • Applicants must submit their applications by Jan 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
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Opportunity Summary:

The grant opportunity PA 10 050, titled "PHS 2010 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44)," is a broad, government-wide solicitation designed to bring new technologies and research-driven products into the federal health and human services mission space through U.S. small businesses. It is essentially an umbrella SBIR announcement that invites eligible U.S. small business concerns to propose early-stage and development-stage research and development projects that align with the research priorities of participating agencies and their specific awarding components. The core idea is to move promising innovations from concept to proof-of-feasibility and then toward more advanced development with a clear path to commercialization and public benefit, while supporting the research and development missions of NIH, CDC, FDA, and ACF.

Eligibility is focused on U.S. small business concerns, meaning applicants must meet the SBIR program requirements for being a qualifying small business in the United States. The opportunity is not open to universities, nonprofits, or individuals as primary applicants unless they are part of a qualifying small business applicant structure. There is no cost sharing or matching requirement listed, which is typical for SBIR grants and lowers the barrier for small companies to pursue R and D that might be too risky to fund privately at an early stage.

This FOA uses the SBIR grant mechanisms R43 and R44, which correspond to different phases of SBIR support. Phase I generally supports feasibility and proof-of-concept work (often smaller in scope and duration), while Phase II supports more substantial R and D efforts aimed at advancing a technology toward a product or service that can be commercialized. The announcement also allows Fast Track applications, which are intended to speed the transition from Phase I to Phase II by submitting an integrated application package. A key structural detail is that this SBIR FOA runs in parallel with an STTR counterpart (PA 10 051) that has identical scientific scope, but STTR applications are only accepted by NIH. The CDC, FDA, and ACF do not participate in STTR under this solicitation. Additionally, SBIR Fast Track and Phase II Competing Renewal applications are accepted only by NIH, which matters for companies deciding how to structure their submission depending on which agency component best fits their project.

Rather than limiting applicants to a narrow set of topics, this is an omnibus solicitation that points applicants to agency topic descriptions and research priorities, specifically referencing "PHS 2010 2 SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, FDA and ACF." In practice, that means a small business is expected to align its proposal to one or more of the participating agencies' missions and to target the relevant institute, center, or program area. The breadth of the participating portfolios is reflected in the wide range of CFDA program areas associated with the solicitation, spanning major biomedical and public health domains such as cancer research (cause and prevention, detection and diagnosis, treatment, biology, and control), cardiovascular, lung, blood, diabetes, digestive and kidney diseases, neurological and mental health research, alcohol and drug abuse programs, infectious disease and microbiology, aging, child health and human development, vision research, nursing research, minority health and health disparities, environmental health and Superfund-related research, occupational safety and health, oral health, human genome research, and medical library assistance, among others. The inclusion of CDC investigations and technical assistance and FDA research categories highlights that proposals may also be relevant to public health practice, surveillance, prevention, regulatory science, safety, efficacy, and technologies that support agency decision-making.

Funding and award volume are not fixed in the announcement. Instead, awards are explicitly contingent on the availability of funds and on the receipt of a sufficient number of meritorious applications. The agencies also note that the total amount awarded and the number of awards will depend on application quality, project duration, and proposed costs. In other words, this is a competitive, peer-reviewed environment where the strength of the science, the feasibility of the development plan, and the overall potential impact and commercialization path will heavily influence whether and how many awards are made.

From an administrative standpoint, this is a discretionary grant opportunity (not a contract), with NIH listed as the lead agency name in the source data, and it was posted and created on January 15, 2010. The original and current closing date shown is January 7, 2011, with an archive date of February 7, 2011, indicating this specific posting is historical, though similar parent SBIR omnibus solicitations are often reissued in later years. The listed eligible applicants category is small businesses, and the funding activity categories are broad, covering education, environment, food and nutrition, health, and income security and social services, which mirrors the cross-cutting missions of NIH, CDC, FDA, and ACF.

Overall, PA 10 050 is best understood as a gateway SBIR announcement for U.S. startups and small companies developing innovations that can improve human health, strengthen public health systems, advance regulatory science, or support social service outcomes tied to health and wellbeing. It provides a standardized set of SBIR submission routes (Phase I, Phase II, and for NIH, Fast Track and certain renewals) while allowing applicants to plug into a very wide range of federal research priorities, so long as the proposed R and D is responsive to the identified topics and the mission of the participating awarding component.

Frequently Asked Questions (FAQs)

What is PA 10 050?

PA 10 050 is the "PHS 2010 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44)." It is a broad, parent SBIR funding opportunity that invites U.S. small businesses to propose research and development (R&D) projects that align with the missions and research priorities of participating federal health and human services agencies.

What is the main purpose of this omnibus SBIR solicitation?

The purpose is to help U.S. small businesses move innovations from concept to feasibility and into more advanced development, with an eye toward commercialization and public benefit. Projects should support the R&D missions of NIH, CDC, FDA, and ACF and contribute to federal health and human services priorities.

Which agencies are included in this solicitation?

The solicitation covers components of NIH, CDC, FDA, and ACF. NIH is listed as the lead agency in the source information, but the scientific scope is designed to span participating agencies and their awarding components.

Who is eligible to apply?

Eligible applicants are U.S. small business concerns that meet SBIR program requirements. The opportunity is not open to universities, nonprofits, or individuals as the primary applicant unless they are applying through a qualifying small business structure.

Is cost sharing or matching required?

No cost sharing or matching requirement is listed for this opportunity, which is typical for SBIR grants.

What SBIR mechanisms (grant types) does this FOA use?

This FOA uses SBIR grant mechanisms R43 and R44. These correspond to different SBIR phases: Phase I (generally feasibility/proof-of-concept) and Phase II (generally more substantial R&D to advance toward commercialization).

What is the difference between Phase I and Phase II under this solicitation?

Phase I generally supports early-stage feasibility and proof-of-concept work and is typically smaller in scope and duration. Phase II generally supports more extensive R&D efforts intended to further develop the technology toward a commercializable product or service.

Are Fast Track applications allowed?

Yes, Fast Track applications are allowed under this announcement, but Fast Track is accepted only by NIH (based on the information provided).

Are Phase II Competing Renewal applications allowed?

Phase II Competing Renewal applications are accepted only by NIH under this solicitation (based on the information provided).

Is there an STTR version of this funding opportunity?

Yes. This SBIR FOA runs in parallel with an STTR counterpart, PA 10 051, with identical scientific scope. However, STTR applications are only accepted by NIH; CDC, FDA, and ACF do not participate in STTR under this solicitation.

Does this solicitation limit applicants to a narrow list of topics?

No. This is an omnibus solicitation, meaning it is broad and points applicants to agency program descriptions and research topics rather than restricting proposals to a small set of topics.

Where do applicants find the topics and research priorities they must align with?

Applicants are directed to the referenced document: "PHS 2010 2 SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, FDA and ACF." Proposals are expected to align with one or more participating agencies' missions and the relevant awarding component’s priorities.

What kinds of project areas appear to be included?

The solicitation spans a wide range of biomedical, public health, and human services-related areas. Examples mentioned include cancer research (prevention, detection/diagnosis, treatment, biology, control), cardiovascular/lung/blood, diabetes, digestive and kidney diseases, neurological and mental health, alcohol and drug abuse, infectious disease and microbiology, aging, child health and human development, vision research, nursing research, minority health and health disparities, environmental health and Superfund-related research, occupational safety and health, oral health, human genome research, and medical library assistance, among others. It also includes CDC-related investigations/technical assistance and FDA research categories relevant to public health practice and regulatory science.

How should a small business choose the best participating agency component for submission?

Based on the information provided, the proposal should be targeted to the agency institute/center/program area whose mission and topic priorities best match the project. A practical consideration is that certain submission routes (SBIR Fast Track and Phase II Competing Renewal) are only accepted by NIH under this solicitation.

Is the funding amount or number of awards guaranteed?

No. Funding levels and award volume are not fixed. Awards are contingent on the availability of funds and on the receipt of a sufficient number of meritorious applications. The total amount awarded and number of awards also depend on application quality, project duration, and proposed costs.

Is this a grant or a contract opportunity?

This is described as a discretionary grant opportunity (not a contract).

What is the competitive environment like for this opportunity?

The opportunity is described as competitive and peer-reviewed. Selection is influenced by scientific strength, feasibility of the development plan, overall potential impact, and the credibility of the commercialization path, along with alignment to the participating agency component’s mission and priorities.

When was this opportunity posted, and what are the closing and archive dates?

The posting/creation date is listed as January 15, 2010. The original and current closing date shown is January 7, 2011. The archive date is February 7, 2011.

Is PA 10 050 still active?

Based on the dates provided (closing date January 7, 2011 and archive date February 7, 2011), this specific posting appears to be historical. The information also notes that similar parent SBIR omnibus solicitations are often reissued in later years.

What applicant type is listed for eligibility?

The listed eligible applicants category is small businesses.

What funding activity categories are associated with this opportunity?

The funding activity categories are broad and include education, environment, food and nutrition, health, and income security and social services, reflecting the cross-cutting missions of NIH, CDC, FDA, and ACF.

What kinds of outcomes does this solicitation aim to support?

It is positioned as a gateway SBIR announcement for innovations that can improve human health, strengthen public health systems, advance regulatory science, and support social service outcomes tied to health and wellbeing, while enabling commercialization and public benefit.

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Next opportunity: PHS 2010 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42)

Previous opportunity: NCMHD Innovative Faith Based Approaches to Health Disparities Research (R21)

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Applicants also applied for:

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Funding Opportunity
PHS 2010 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) Apply for PA 10 051

Funding Number: PA 10 051
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health Related Research (Parent F31 Diversity) Apply for PA 10 109

Funding Number: PA 10 109
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (Parent F32) Apply for PA 10 110

Funding Number: PA 10 110
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Understanding and Promoting Health Literacy (R01) Apply for PAR 10 133

Funding Number: PAR 10 133
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R01) Apply for PAR 10 136

Funding Number: PAR 10 136
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Advancing Novel Science in Womens Health Research (ANSWHR) (R21) Apply for PAS 10 226

Funding Number: PAS 10 226
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $200,000
Effects of the Social Environment on Health Measurement, Methods and Mechanisms (R01) Apply for RFA DA 11 003

Funding Number: RFA DA 11 003
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Sleep and Social Environment Basic Biopsychosocial Processes (R21) Apply for RFA HD 11 102

Funding Number: RFA HD 11 102
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $200,000
Sleep and Social Environment Basic Biopsychosocial Processes (R01) Apply for RFA HD 11 101

Funding Number: RFA HD 11 101
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $250,000
Basic Research on Self Regulation (R21) Apply for RFA AG 11 010

Funding Number: RFA AG 11 010
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $275,000
Psychosocial Stress and Behavior Integration of Behavioral and Physiological Processes (R01) Apply for RFA HL 11 033

Funding Number: RFA HL 11 033
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $400,000
Development of Comprehensive and Conceptually based Measures of Psychosocial Stress (R21) Apply for RFA HL 11 034

Funding Number: RFA HL 11 034
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $200,000
Basic Mechanisms Influencing Behavioral Maintenance (R01) Apply for RFA HL 11 035

Funding Number: RFA HL 11 035
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $500,000
Scientific Meetings for Creating Interdisciplinary Research Teams in Basic Behavioral and Social Science Research (R13) Apply for RFA CA 10 017

Funding Number: RFA CA 10 017
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
NIH Basic Behavioral and Social Science Opportunity Network (OppNet) Short term Interdisciplinary Training Program for New and Early Stage Investigators (R25) Apply for RFA NR 11 002

Funding Number: RFA NR 11 002
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $150,000
NIH Blueprint for Neuroscience Research Short Courses in Neurotherapeutics Development (R25) Apply for RFA NS 12 001

Funding Number: RFA NS 12 001
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $250,000
PHS 2011 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) Apply for PA 11 097

Funding Number: PA 11 097
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $100,000
PHS 2011 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44) Apply for PA 11 096

Funding Number: PA 11 096
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: $150,000
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health Related Research (Parent F31 Diversity) Apply for PA 11 112

Funding Number: PA 11 112
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (Parent T32) Apply for PA 11 184

Funding Number: PA 11 184
Agency: National Institutes of Health
Category: Education Environment Food and Nutrition Health Income Security and Social Services
Funding Amount: Case Dependent

 

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