Opportunity Information: Apply for PAR 06 358

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Planning Grants For Translational Research For The Prevention And Control Of Diabetes And Obesity (R34)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Dec 5, 2008 and posted on Apr 13, 2006.
  • Applicants must submit their applications by May 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $150,000.00 in funding.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Special district governments Private institutions of higher education Independent school districts For profit organizations other than small businesses Native American tribal governments (Federally recognized).
  • Foreign institutions are not eligible to apply. Eligible agencies of the Federal Government are eligible to apply. Domestic Institutions Faith based or community based organizations Indian/Native American Tribal Government (Federally Recognized) Indian/Native American Tribal Government (Other than Federally Recognized) Indian/Native American Tribally Designated Organization
Apply for PAR 06 358

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Opportunity Summary:

The Planning Grants for Translational Research for the Prevention and Control of Diabetes and Obesity (R34) funding opportunity (PAR-06-358) is a National Institutes of Health program run by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its main purpose is to help move diabetes and obesity interventions that already worked in controlled clinical trials into real-world settings where they can be used at scale. The emphasis is on translation and dissemination: taking what is already known to be effective and figuring out how to implement it in everyday health care systems and community environments in ways that are practical, affordable, and durable over time.

This announcement specifically supports planning grants and pilot studies rather than full-scale trials. Applicants are expected to use the R34 mechanism to generate the groundwork needed for a larger, definitive study later on. That groundwork can include early testing of implementation approaches, refining intervention delivery models, developing partnerships with delivery settings, working through logistical barriers, and collecting preliminary evidence that the approach is feasible and shows promise for meaningful health outcomes. NIDDK is looking for preliminary data indicating that the proposed strategy can realistically be delivered outside a research bubble and that it can lead to outcomes such as reduced body weight and/or improved glycemia, with a strong preference for strategies that are cost-effective and sustainable.

The scientific scope centers on preventing and controlling diabetes and obesity using interventions that have already demonstrated efficacy. Priority topic areas include improving health care delivery for people who have diabetes or are at risk, strengthening diabetes self-management support, creating and testing strategies that promote healthy lifestyles to reduce diabetes risk, promoting lifestyle change that prevents or reverses overweight and obesity, and developing new cost-effective ways to identify people with prediabetes or undiagnosed diabetes. In addition to glycemic control, the program highlights the importance of addressing major risk factors for diabetes complications such as hypertension and dyslipidemia, reflecting a broader goal of reducing long-term morbidity through better overall risk-factor management.

A defining feature of this opportunity is the expectation that proposed interventions be designed for broad dissemination and implementation in existing, representative settings in the United States. The FOA points to places like health care systems, schools, worksites, and other community-based environments as target implementation sites. Applications should show that the intervention can fit into routine workflows and real resource constraints, rather than relying on intensive research staffing or unusually high levels of support that would not be available after the study ends. The program also explicitly encourages proposals that focus on minority populations and other groups at elevated risk who are disproportionately affected by diabetes and obesity, aligning with public health goals around equity and reducing disparities.

From an applicant and eligibility standpoint, the program is open to a wide range of domestic organizations, including for-profit and non-profit entities, public and private institutions (such as universities, colleges, hospitals, and laboratories), units of state and local government, eligible federal agencies, and faith-based or community-based organizations. Tribal governments and tribally designated organizations are also eligible. Foreign institutions are not eligible to apply. For investigators, the announcement is intentionally inclusive: any individual with the skills, knowledge, and resources to lead the work may serve as a Project Director/Principal Investigator, and the FOA encourages applications from investigators new to diabetes and obesity research as well as individuals from underrepresented racial and ethnic groups and individuals with disabilities. Multiple applications may be submitted by the same applicant as long as they are scientifically distinct and do not overlap in scope or budget.

In terms of funding details, this is a discretionary grant opportunity in the health area (CFDA 93.847) with no cost sharing or matching requirement. Award size and duration are expected to vary depending on what the pilot or planning work requires, and the number of awards depends on the volume and quality of applications and available funds. The source listing notes an award ceiling of $150,000. The FOA had multiple receipt dates, with the last listed closing date of May 7, 2009, and an archive date of June 7, 2009, indicating it is not a currently open competition but remains a useful reference for how NIDDK frames translational planning support in this area.

Finally, the R34 mechanism here is positioned as a stepping stone to larger-scale research, and the announcement points to a companion program announcement with the same scientific scope that uses the R18 translational research project grant mechanism (PA-02-153). In practical terms, this R34 FOA is meant for teams that have a strong evidence-based intervention in hand and need targeted support to plan, adapt, pilot, and demonstrate feasibility and real-world potential before launching a broader dissemination or implementation study.

Frequently Asked Questions (FAQs)

What is the “Planning Grants for Translational Research for the Prevention and Control of Diabetes and Obesity (R34)” opportunity?

It is a National Institutes of Health (NIH) funding opportunity (PAR-06-358) run by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It supports planning grants and pilot studies to help move diabetes and obesity interventions that already worked in controlled clinical trials into real-world settings where they can be used at scale.

What is the main purpose of this R34 program?

The purpose is translation and dissemination: taking interventions that have already demonstrated efficacy and figuring out how to implement them in everyday health care systems and community environments in ways that are practical, affordable, and durable over time.

Is this opportunity intended to fund full-scale clinical trials?

No. This announcement specifically supports planning grants and pilot studies rather than full-scale trials. The expectation is that R34 work will generate groundwork for a larger, definitive study later.

What kinds of activities can an R34 planning grant support under this announcement?

Supported activities include generating the groundwork needed for a larger study, such as early testing of implementation approaches, refining intervention delivery models, developing partnerships with delivery settings, working through logistical barriers, and collecting preliminary evidence that the approach is feasible and shows promise for meaningful health outcomes.

What kind of evidence or outcomes is NIDDK looking for from proposed projects?

NIDDK is looking for preliminary data indicating the proposed strategy can realistically be delivered outside a research-only environment and can lead to outcomes such as reduced body weight and/or improved glycemia. There is a strong preference for strategies that are cost-effective and sustainable.

What is the scientific scope of the program?

The scope centers on preventing and controlling diabetes and obesity using interventions that have already demonstrated efficacy in controlled clinical trials, with an emphasis on translating those interventions into representative real-world settings in the United States.

What priority topic areas are highlighted in the announcement?

Priority areas include improving health care delivery for people who have diabetes or are at risk; strengthening diabetes self-management support; creating and testing strategies that promote healthy lifestyles to reduce diabetes risk; promoting lifestyle change that prevents or reverses overweight and obesity; and developing new cost-effective ways to identify people with prediabetes or undiagnosed diabetes.

Does the program focus only on blood sugar (glycemia) outcomes?

No. In addition to glycemic control, the program emphasizes addressing major risk factors for diabetes complications such as hypertension and dyslipidemia, reflecting a broader goal of reducing long-term morbidity through improved overall risk-factor management.

What makes an intervention a good fit for this translational R34?

A good fit is an intervention that has already shown efficacy and is designed to be broadly disseminated and implemented in existing, representative U.S. settings. Applications should show the intervention can fit into routine workflows and real resource constraints, rather than requiring intensive research staffing or unusually high support that would not be available after the study ends.

What types of real-world settings are mentioned as implementation sites?

The announcement points to settings such as health care systems, schools, worksites, and other community-based environments as target sites for implementation.

Are projects expected to plan for dissemination and long-term sustainability?

Yes. A defining feature is the expectation that interventions be designed for broad dissemination and implementation, with attention to practicality, affordability, and durability over time, including a preference for cost-effective and sustainable approaches.

Does the program encourage proposals focused on health equity or high-risk populations?

Yes. The program explicitly encourages proposals that focus on minority populations and other groups at elevated risk who are disproportionately affected by diabetes and obesity.

Who is eligible to apply as an organization?

The program is open to a wide range of domestic organizations, including for-profit and non-profit entities; public and private institutions (such as universities, colleges, hospitals, and laboratories); units of state and local government; eligible federal agencies; and faith-based or community-based organizations. Tribal governments and tribally designated organizations are also eligible.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply under this announcement.

Who can serve as the Project Director/Principal Investigator (PD/PI)?

Any individual with the skills, knowledge, and resources to lead the work may serve as PD/PI. The announcement encourages applications from investigators new to diabetes and obesity research, as well as individuals from underrepresented racial and ethnic groups and individuals with disabilities.

Can the same applicant submit more than one application?

Yes. Multiple applications may be submitted by the same applicant as long as they are scientifically distinct and do not overlap in scope or budget.

What is the CFDA number and what does it indicate?

The source listing identifies this opportunity as CFDA 93.847, indicating it is a discretionary grant opportunity in the health area.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

How much funding is available per award?

Award size and duration are expected to vary depending on what the pilot or planning work requires. The source listing notes an award ceiling of $150,000.

How many awards will be made?

The number of awards depends on the volume and quality of applications and the availability of funds.

Is this funding opportunity currently open?

No. The last listed closing date was May 7, 2009, with an archive date of June 7, 2009, indicating it is not a currently open competition (though it can still be a useful reference for how NIDDK frames translational planning support).

How does this R34 relate to other NIDDK translational funding mechanisms mentioned?

The announcement notes a companion program announcement with the same scientific scope that uses the R18 translational research project grant mechanism (PA-02-153). In practical terms, the R34 is positioned as a stepping stone to larger-scale research.

What is the practical “stepping stone” role of this R34?

This R34 is meant for teams that have a strong evidence-based intervention in hand and need targeted support to plan, adapt, pilot, and demonstrate feasibility and real-world potential before launching a broader dissemination or implementation study.

Browse more business programs for Diabetes Research

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Previous opportunity: Building Translational Research in Integrative Behavioral Science (R21)

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