Opportunity Information: Apply for CDC RFA GH11 11500502SUPP16

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 18, 2016.
  • Applicants must submit their applications by Oct 17, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,509,161.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH11 11500502SUPP16

[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:

Opportunity Summary:

This grant opportunity, titled "Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR," is a CDC cooperative agreement supplement intended to expand voluntary medical male circumcision (VMMC) services in South Africa as a high-impact HIV prevention strategy. The core rationale is that VMMC is a one-time clinical procedure that provides long-lasting protection by reducing a man's risk of acquiring HIV through heterosexual exposure over his lifetime. The announcement points to strong evidence from three randomized controlled trials showing roughly a 60% reduction in HIV acquisition risk among circumcised men, with longer-term follow-up from Uganda and Kenya suggesting the protective effect is sustained and may even increase over time (reported ranges include about 67-73% in one follow-up and about 58% in another). Because of this evidence base, WHO and UNAIDS issued guidance in 2007 recognizing VMMC as an important additional HIV prevention intervention, and they promoted rapid scale-up in countries in Eastern and Southern Africa where HIV burden is high and baseline male circumcision prevalence is relatively low.

A major theme of the opportunity is acceleration and coverage. The broader regional framework referenced in the announcement set an ambitious target of reaching 80% circumcision coverage among males ages 15-49 across 14 priority countries, translating to an estimated 20.3 million circumcisions by the end of 2016. The announcement also cites mathematical modeling suggesting that if 8 out of 10 adult men become circumcised within a five-year period, the public health payoff could be substantial: about 3.4 million new HIV infections averted over 15 years and as much as $16.5 billion saved in HIV care and treatment costs. For South Africa specifically, the modeling highlighted in the notice suggests that, under that rapid scale-up scenario, roughly one HIV infection could be prevented for every five men circumcised, underscoring why CDC and PEPFAR view VMMC as one of the most efficient prevention investments available.

Beyond the direct effect for men, the announcement emphasizes broader prevention benefits built into VMMC programming. PEPFAR-supported VMMC services are framed as an entry point for reaching men who may otherwise have limited contact with the health system, creating opportunities for health education and risk-reduction counseling. HIV testing and counseling is described as a recommended and routinely provided component of PEPFAR VMMC programs, which helps identify clients living with HIV and link them to care and treatment. This linkage is presented not only as a clinical benefit for the individual, but also as a community-level prevention gain because people on effective HIV treatment are far less likely to transmit HIV to sexual partners, reinforcing the idea that VMMC scale-up can complement treatment-as-prevention.

The opportunity also highlights indirect but meaningful benefits for women. As circumcision coverage increases and male HIV incidence and prevalence decline, women face a lower probability of encountering an HIV-positive partner, meaning women can experience reduced HIV risk even though the procedure is performed on men. The cited modeling suggests that with rapid scale-up, nearly half of the infections averted could occur among women. In addition, the notice references evidence that women with circumcised male partners may have reduced risk of certain sexually transmitted infections, including carcinogenic strains of HPV, which are associated with cervical cancer. These points are used to justify VMMC as a prevention approach with cross-cutting sexual and reproductive health implications rather than a narrowly targeted surgical service.

In practical terms, this is a supplement designed to add funding to existing CDC South Africa partners rather than a broad open solicitation for entirely new implementers. The stated purpose is to support scale-up of VMMC in 27 high-burden districts and in sub-districts with low male circumcision prevalence, indicating a geographic prioritization strategy focused on areas where HIV incidence is high and where increasing circumcision coverage could have the greatest marginal impact. The funding mechanism is a discretionary cooperative agreement, which typically implies substantial programmatic involvement by CDC in planning, implementation, monitoring, and performance improvement.

Key administrative details from the notice include: the funding opportunity number is CDC RFA GH11-11500502SUPP16; it was issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under the health activity category (CFDA 93.067). The opportunity was created on August 18, 2016, with an original closing date of October 17, 2016, and applications were required to be submitted electronically by 11:59 p.m. ET on the due date. The expected number of awards was one, and the award ceiling listed was $2,509,161. Eligibility is described as "Others," with clarification referenced in an additional information field, but the narrative description makes clear the intent to provide additional funds to existing CDC South Africa partners to expand VMMC service delivery in priority locations under PEPFAR.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR."

Which agency is offering this opportunity?

It is issued by the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC).

What type of funding is this?

This is a CDC cooperative agreement supplement, meaning it is intended to add funds to an existing cooperative agreement and typically involves substantial CDC programmatic involvement in planning, implementation, monitoring, and performance improvement.

What is the main purpose of the supplement?

The stated purpose is to expand voluntary medical male circumcision (VMMC) services in South Africa as a high-impact HIV prevention strategy under PEPFAR.

Is the circumcision service described as voluntary?

Yes. The program emphasis is on voluntary medical male circumcision (VMMC).

Where will the supported activities take place?

The supplement is focused on South Africa, with scale-up targeted in 27 high-burden districts and in sub-districts with low male circumcision prevalence.

Why is VMMC considered a high-impact HIV prevention strategy?

The notice describes VMMC as a one-time clinical procedure that provides long-lasting protection by reducing a man's risk of acquiring HIV through heterosexual exposure over his lifetime.

What evidence does the announcement cite for VMMC effectiveness?

The announcement points to evidence from three randomized controlled trials indicating roughly a 60% reduction in HIV acquisition risk among circumcised men, with longer-term follow-up in Uganda and Kenya suggesting protection is sustained and may increase over time (with reported follow-up ranges including about 67-73% in one follow-up and about 58% in another).

How does this opportunity relate to WHO and UNAIDS guidance?

The notice references 2007 WHO and UNAIDS guidance recognizing VMMC as an important additional HIV prevention intervention and promoting rapid scale-up in Eastern and Southern African countries with high HIV burden and relatively low baseline male circumcision prevalence.

What scale-up goal is referenced in the announcement?

The broader regional framework cited includes a target of reaching 80% circumcision coverage among males ages 15-49 across 14 priority countries, translating to an estimated 20.3 million circumcisions by the end of 2016.

What public health impact does the announcement associate with rapid scale-up?

The announcement cites mathematical modeling suggesting that if 8 out of 10 adult men become circumcised within five years, approximately 3.4 million new HIV infections could be averted over 15 years, with as much as $16.5 billion saved in HIV care and treatment costs.

What does the modeling suggest specifically for South Africa?

For South Africa, the modeling highlighted suggests that under rapid scale-up, roughly one HIV infection could be prevented for every five men circumcised, which the notice uses to support the view that VMMC is a highly efficient prevention investment.

Does the program include HIV testing and counseling?

Yes. HIV testing and counseling is described as a recommended and routinely provided component of PEPFAR VMMC programs.

How does VMMC programming connect clients to HIV care and treatment?

The notice explains that routine HIV testing and counseling can help identify clients living with HIV and link them to care and treatment, which is presented as both an individual clinical benefit and a community-level prevention benefit because effective treatment reduces the likelihood of transmission to sexual partners.

Does the announcement describe benefits beyond men receiving the procedure?

Yes. It emphasizes broader prevention benefits, including reaching men who may otherwise have limited contact with the health system, providing health education and risk-reduction counseling, and generating indirect prevention benefits for women as male HIV incidence and prevalence decline.

How might women benefit according to the announcement?

The notice states that as circumcision coverage increases and male HIV incidence and prevalence fall, women face a lower probability of encountering an HIV-positive partner. It also cites modeling suggesting that with rapid scale-up, nearly half of infections averted could occur among women.

Does the notice mention any additional sexual and reproductive health benefits?

Yes. It references evidence that women with circumcised male partners may have reduced risk of certain sexually transmitted infections, including carcinogenic strains of HPV associated with cervical cancer.

Is this opportunity open to new applicants or intended for existing partners?

The narrative description indicates it is a supplement designed to add funding to existing CDC South Africa partners rather than a broad open solicitation for entirely new implementers.

What is the funding opportunity number?

The funding opportunity number is CDC RFA GH11-11500502SUPP16.

What is the CFDA number and activity category?

The notice lists the health activity category and CFDA 93.067.

When was the opportunity created?

The opportunity was created on August 18, 2016.

What was the original closing date for applications?

The original closing date was October 17, 2016.

How were applications required to be submitted?

Applications were required to be submitted electronically.

What was the application submission deadline time?

Applications were due by 11:59 p.m. Eastern Time (ET) on the due date.

How many awards were expected?

The expected number of awards was one.

What is the award ceiling listed in the notice?

The award ceiling listed was $2,509,161.

Who is eligible to apply?

Eligibility is described as "Others," with additional clarification referenced in an additional information field. However, the narrative indicates the intent is to provide additional funds to existing CDC South Africa partners to expand VMMC service delivery in priority locations under PEPFAR.

What is PEPFAR's role in this opportunity?

The opportunity is explicitly under PEPFAR and frames VMMC as a core HIV prevention strategy supported through PEPFAR programming in South Africa.

Why does the notice emphasize acceleration and coverage?

The announcement ties rapid increases in circumcision coverage to large modeled reductions in HIV infections and major cost savings in HIV care and treatment, and it highlights prioritization of high-burden districts and areas with low baseline circumcision prevalence to maximize impact.

Browse more opportunities from the same agency: Department of Health and Human Services, Centers for Disease Control - CGH

Browse more opportunities from the same category: Health

Next opportunity: Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR

Previous opportunity: AAAS Science and Technology Policy Fellowship - Promoting International Preservation and Research

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for CDC RFA GH11 11500502SUPP16

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (CDC RFA GH11 11500502SUPP16) also looked into and applied for these:

Funding Opportunity
Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR Apply for CDC RFA GH11 11500501SUPP16

Funding Number: CDC RFA GH11 11500501SUPP16
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: $832,078
Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAR Apply for CDC RFA GH11 11500503SUPP16

Funding Number: CDC RFA GH11 11500503SUPP16
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: $5,489,235
Maximizing Investigator's Research Award for New and Early Stage Investigators (R35) Apply for RFA GM 17 004

Funding Number: RFA GM 17 004
Agency: Department of Health and Human Services, National Institutes of Health
Category: Health
Funding Amount: $250,000
National Action Partnership to Promote Safe Sleep Program Apply for HRSA 17 094

Funding Number: HRSA 17 094
Agency: Department of Health and Human Services, Health Resources and Services Administration
Category: Health
Funding Amount: Case Dependent
CDC Mexico Co-Ag for Surveillance & Epidemiology Apply for CDC RFA CK11 11060501SUPP16

Funding Number: CDC RFA CK11 11060501SUPP16
Agency: Department of Health and Human Services, Centers for Disease Control - NCEZID
Category: Health
Funding Amount: $5,000,000
Protecting and Strengthening Public Health Impact, Systems, Capacity, and Security Apply for CDC RFA GH14 141802CONT17

Funding Number: CDC RFA GH14 141802CONT17
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: Case Dependent
Program Expansion Supplement: Supporting Laboratory Strengthening Activities in Resource-Limited Countries under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH13 13660301SUPP16

Funding Number: CDC RFA GH13 13660301SUPP16
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: $500,000
Program Expansion Supplement: Supporting Laboratory Strengthening Activities in Resource-Limited Countries under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH13 13660302SUPP16

Funding Number: CDC RFA GH13 13660302SUPP16
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: $1,500,000
Technical Assistance to Obtain State and Territorial Health Department Input for Health Care System and Hospital Preparedness Related Activities Apply for EP HIT 16 003

Funding Number: EP HIT 16 003
Agency: Department of Health and Human Services, Assistant Secretary for Preparedness and Response
Category: Health
Funding Amount: $500,000
Communication For Improved Health Outcomes (CIHO) Apply for RFA 656 16 000015

Funding Number: RFA 656 16 000015
Agency: Agency for International Development, Mozambique USAID-Maputo
Category: Health
Funding Amount: $999,887
Population-Based Surveillance of Birth Defects and Data Utilization for Public Health Action Apply for CDC RFA DD16 160102CONT17

Funding Number: CDC RFA DD16 160102CONT17
Agency: Department of Health and Human Services, Centers for Disease Control - NCBDDD
Category: Health
Funding Amount: Case Dependent
Rape Prevention and Education Apply for CDC RFA CE14 140104CONT17

Funding Number: CDC RFA CE14 140104CONT17
Agency: Department of Health and Human Services, Centers for Disease Control - NCIPC
Category: Health
Funding Amount: Case Dependent
STD/HIV Disease Intervention Services Training Centers (DISTC) National Center for HIV, Viral Hepatitis, STD and TB Prevention (NCHHSTP) Apply for CDC RFA PS14 140804CONT17

Funding Number: CDC RFA PS14 140804CONT17
Agency: Department of Health and Human Services, Centers for Disease Control - NCHHSTP
Category: Health
Funding Amount: Case Dependent
SUPPORT FOR ORPHANS AND VULNERABLE CHILDREN (OVC) IN KENYA Apply for NOFO 615 16 000033

Funding Number: NOFO 615 16 000033
Agency: Agency for International Development
Category: Health
Funding Amount: $64,000,000
Rural Health Research Dissemination Cooperative Agreement Apply for HRSA 17 002

Funding Number: HRSA 17 002
Agency: Department of Health and Human Services, Health Resources and Services Administration
Category: Health
Funding Amount: Case Dependent
Resilient and Responsive Health Organizations: Sustainability Communities of Practice Initiative (RRHO) Apply for HRSA 17 032

Funding Number: HRSA 17 032
Agency: Department of Health and Human Services, Health Resources and Services Administration
Category: Health
Funding Amount: Case Dependent
Engaging Youth and Young Adults from Health Disparity Populations in the HIV Treatment Cascade (R01) Apply for RFA MD 16 003

Funding Number: RFA MD 16 003
Agency: Department of Health and Human Services, National Institutes of Health
Category: Health
Funding Amount: $500,000
Service Area Competition Apply for HRSA 17 054

Funding Number: HRSA 17 054
Agency: Department of Health and Human Services, Health Resources and Services Administration
Category: Health
Funding Amount: Case Dependent
Strengthening Ebola rapid detection and response capacity through community based surveillance and safe burial practices Apply for CDC RFA GH16 1722

Funding Number: CDC RFA GH16 1722
Agency: Department of Health and Human Services, Centers for Disease Control - CGH
Category: Health
Funding Amount: Case Dependent
Accountable Health Communities Track 1 - Awareness Apply for CMS 1P1 17 002

Funding Number: CMS 1P1 17 002
Agency: Department of Health and Human Services, Centers for Medicare Medicaid Services
Category: Health
Funding Amount: $1,170,000

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

USGrants.org applicant portal membership

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "CDC RFA GH11 11500502SUPP16", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.