Opportunity Information: Apply for CDC RFA GH15 15370201SUPP16

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Technical Assistance to Provide High-Quality Voluntary Medical Male Circumcision (VMMC) Services to Programs Supported by the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 17, 2016.
  • Applicants must submit their applications by Oct 16, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH15 15370201SUPP16

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Opportunity Summary:

This funding opportunity is a CDC (HHS) cooperative agreement supplement designed to expand and strengthen technical assistance for Voluntary Medical Male Circumcision (VMMC) programs supported by PEPFAR. The core public health rationale is that VMMC is a one-time medical procedure that permanently lowers a male's risk of acquiring HIV through heterosexual exposure. The opportunity is focused on 14 priority countries in eastern and southern Africa where HIV epidemics are generalized and baseline male circumcision levels are low either nationally or in specific regions. In these settings, scaling VMMC is presented as both a high-impact prevention strategy and a cost-saving investment, because preventing infections reduces long-term costs for HIV treatment and care.

The announcement highlights modeling that frames the expected impact: if 80 percent of adult men opt for circumcision within five years, an estimated 3.5 million new HIV infections could be averted over 15 years, with potential savings up to $16.5 billion in HIV care and treatment costs. In 10 of the 14 priority countries, the model suggests that preventing one HIV infection may require circumcising 10 or fewer males under this scale-up scenario. The program also emphasizes broader prevention benefits beyond men themselves. As male HIV prevalence declines through VMMC scale-up, women face a lower probability of exposure to an HIV-infected partner; the notice states that nearly half of the infections prevented under rapid scale-up could be among women. It also notes additional sexual and reproductive health benefits, including reduced risk of certain sexually transmitted infections for women, such as carcinogenic HPV strains linked to cervical cancer.

A major theme of the opportunity is that VMMC service delivery should be comprehensive, integrated, and consistently safe. CDC and PEPFAR expect supported programs to provide a minimum package of clinical and prevention services around the circumcision procedure. That package includes offering (and ensuring availability of) HIV testing and counseling to all men seeking VMMC and, when feasible, to their partners as well. It includes active referral for clients who test HIV-positive to appropriate HIV care and treatment services, and age-appropriate sexual risk-reduction counseling. Programs are expected to counsel clients on abstaining from sex during wound healing and to promote correct and consistent condom use afterward. Clinically, the minimum package includes pre-procedure screening (focused physical exam and medical history) to identify STIs and contraindications, treatment of detected STIs, performing circumcision using a WHO-recognized medical method (surgical or an approved device), and post-procedure follow-up with systematic assessment and monitoring of adverse events.

Quality and safety are positioned as the highest priority, and the supplement is closely tied to building systems that measure and continuously improve service quality at scale. CDC and PEPFAR explicitly point to the need for Continuous Quality Improvement (CQI) and External Quality Assurance (EQA) assessments. These mechanisms are intended to help ministries of health and implementing partners monitor VMMC programs objectively and verify that services meet clinical standards of care, align with international best practices, and comply with PEPFAR technical considerations and policy guidance. In practical terms, the grant is about ensuring that scale-up does not come at the expense of clinical quality, infection prevention, adverse event management, proper counseling, and effective linkage to HIV services.

The opportunity is framed within broader PEPFAR strategy documents, including the PEPFAR Blueprint: Creating an AIDS-free Generation, where increasing male circumcision coverage is a named action step, and the Road Map for Smart Investments, which emphasizes VMMC as a way to engage men and boys in knowing their HIV status and linking those who are positive to treatment. The notice also points to prior progress, stating that by the end of 2013 PEPFAR had met the 2011 World AIDS Day goal by directly supporting 4.7 million VMMC procedures. This supplement is described as building on that success and pushing further toward a stated coverage target: reaching 80 percent VMMC coverage among males aged 15 to 49 through improvements in availability, integration with HIV services, safety, and overall quality of prevention, care, and treatment services.

From an administrative standpoint, this is a discretionary funding opportunity administered by the Centers for Disease Control and Prevention (CDC), Center for Global Health, using a cooperative agreement mechanism (meaning CDC typically has substantial programmatic involvement compared with a standard grant). The funding opportunity number is CDC RFA GH15-15370201SUPP16 under CFDA 93.067. It anticipated a single award with an award ceiling of $2,000,000. The original posting date was August 17, 2016, with an original closing date of October 16, 2016, and applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date. Eligibility is listed broadly as "Others," with specifics referenced in the full eligibility text of the notice.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This opportunity is a CDC (HHS) cooperative agreement supplement intended to expand and strengthen technical assistance for Voluntary Medical Male Circumcision (VMMC) programs supported by PEPFAR.

Which agency is administering the award?

The opportunity is administered by the Centers for Disease Control and Prevention (CDC), Center for Global Health, within the U.S. Department of Health and Human Services (HHS).

What is the funding mechanism and what does it imply?

The mechanism is a cooperative agreement supplement. A cooperative agreement typically means CDC has substantial programmatic involvement compared with a standard grant.

What is the funding opportunity number and CFDA number?

The funding opportunity number is CDC RFA GH15-15370201SUPP16, under CFDA 93.067.

What is the main public health rationale for VMMC in this announcement?

The announcement frames VMMC as a one-time medical procedure that permanently lowers a male's risk of acquiring HIV through heterosexual exposure.

How does the notice describe the expected impact of scaling VMMC?

It cites modeling that if 80 percent of adult men opt for circumcision within five years, an estimated 3.5 million new HIV infections could be averted over 15 years, with potential savings up to $16.5 billion in HIV care and treatment costs.

What scale-up target is emphasized?

The notice highlights a stated coverage target of reaching 80 percent VMMC coverage among males aged 15 to 49, supported by improvements in availability, integration with HIV services, safety, and overall quality of prevention, care, and treatment services.

Where is the program focus geographically?

The opportunity focuses on 14 priority countries in eastern and southern Africa where HIV epidemics are generalized and baseline male circumcision levels are low either nationally or in specific regions.

Why are these 14 countries prioritized?

They are described as settings with generalized HIV epidemics and low baseline male circumcision levels, making VMMC scale-up a high-impact prevention strategy.

How does the opportunity describe VMMC as a cost-saving investment?

It explains that preventing HIV infections reduces long-term costs for HIV treatment and care, and it references potential savings up to $16.5 billion under the modeled rapid scale-up scenario.

What does the announcement say about how many circumcisions may be needed to prevent one HIV infection?

In 10 of the 14 priority countries, the model suggests that preventing one HIV infection may require circumcising 10 or fewer males under the scale-up scenario described.

Does the notice discuss benefits for women?

Yes. It states that as male HIV prevalence declines through VMMC scale-up, women face a lower probability of exposure to an HIV-infected partner, and that nearly half of the infections prevented under rapid scale-up could be among women.

Does the notice mention any other sexual and reproductive health benefits?

Yes. It notes reduced risk of certain sexually transmitted infections for women, including carcinogenic HPV strains linked to cervical cancer.

What is meant by a "minimum package" of services around VMMC?

The announcement expects VMMC service delivery to be comprehensive, integrated, and consistently safe, including a minimum package of clinical and prevention services delivered around the circumcision procedure.

What HIV-related services are expected to be offered to men seeking VMMC?

The minimum package includes offering (and ensuring availability of) HIV testing and counseling to all men seeking VMMC.

Are partners included in HIV testing and counseling expectations?

When feasible, the notice indicates HIV testing and counseling should also be offered to clients' partners.

What is expected for clients who test HIV-positive?

Programs are expected to actively refer clients who test HIV-positive to appropriate HIV care and treatment services.

What type of counseling is expected as part of the VMMC package?

The notice includes age-appropriate sexual risk-reduction counseling, counseling on abstaining from sex during wound healing, and promotion of correct and consistent condom use afterward.

What clinical screening is expected before the procedure?

The minimum package includes pre-procedure screening with a focused physical exam and medical history to identify sexually transmitted infections (STIs) and contraindications.

How should STIs identified during screening be handled?

The notice indicates that detected STIs should be treated as part of the clinical package.

What circumcision methods are permitted under the described expectations?

The circumcision is expected to be performed using a WHO-recognized medical method, either surgical or an approved device.

What follow-up is expected after circumcision?

Post-procedure follow-up is expected, including systematic assessment and monitoring of adverse events.

How does the opportunity prioritize quality and safety?

Quality and safety are described as the highest priority, with an emphasis on ensuring scale-up does not come at the expense of clinical quality, infection prevention, adverse event management, proper counseling, and effective linkage to HIV services.

What quality systems are specifically referenced?

The announcement explicitly references Continuous Quality Improvement (CQI) and External Quality Assurance (EQA) assessments.

What are CQI and EQA intended to accomplish in this program context?

They are intended to help ministries of health and implementing partners monitor VMMC programs objectively and verify that services meet clinical standards of care, align with international best practices, and comply with PEPFAR technical considerations and policy guidance.

How does this supplement relate to broader PEPFAR strategies?

The notice situates the work within documents such as the PEPFAR Blueprint: Creating an AIDS-free Generation (which names increasing male circumcision coverage as an action step) and the Road Map for Smart Investments (which emphasizes VMMC as a way to engage men and boys in knowing their HIV status and linking those who are positive to treatment).

Does the announcement mention prior PEPFAR progress on VMMC?

Yes. It states that by the end of 2013, PEPFAR had met the 2011 World AIDS Day goal by directly supporting 4.7 million VMMC procedures.

How many awards were anticipated and what was the funding ceiling?

The announcement anticipated a single award, with an award ceiling of $2,000,000.

What are the key posting and closing dates included in the notice?

The original posting date was August 17, 2016, and the original closing date was October 16, 2016.

How were applications required to be submitted?

Applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date.

Who is eligible to apply based on the information provided?

Eligibility is listed broadly as "Others," with specifics referenced in the full eligibility text of the notice.

Is this opportunity described as mandatory or discretionary funding?

It is described as a discretionary funding opportunity.

What is the central implementation message of the opportunity?

The core message is that VMMC scale-up should be comprehensive, integrated with HIV services, and consistently safe, supported by strong quality measurement and continuous improvement so that increased volume does not compromise clinical standards.

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