Opportunity Information: Apply for PAR 13 188
Apply for PAR 13 188
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Reducing the Duration of Untreated Psychosis in the United States (R34)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Apr 10, 2013 and posted on Apr 10, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $225,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education County governments Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts City or township governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Native American tribal governments (Federally recognized) State governments Special district governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity PAR-13-188, titled "Reducing the Duration of Untreated Psychosis in the United States (R34)," focuses on a major gap in how quickly young people in the U.S. receive effective care after the start of psychosis. Each year, an estimated 100,000 adolescents and young adults experience a first episode of psychosis (FEP). The earliest phase of psychotic illness is widely seen as a uniquely important window, because timely, phase-specific care can potentially change long-term trajectories and reduce the serious clinical and functional declines often associated with conditions like schizophrenia. The opportunity is rooted in a consistent research finding: outcomes tend to be better when treatment begins close to symptom onset, yet in the U.S. there is often a long delay before people receive appropriate specialty care.
A central issue the announcement targets is the duration of untreated psychosis (DUP), meaning the time between the onset of psychotic symptoms and the start of adequate treatment. Many studies show that in the United States this delay commonly ranges from one to three years. That gap matters because it can allow symptoms, disability, and social or educational disruption to compound before a person ever reaches a program designed to treat early psychosis. Specialty, multi-component FEP programs have demonstrated benefits across clinical symptoms and day-to-day functioning, but those benefits are harder to achieve when people are referred late or disengage during the early phase. The FOA aligns with the World Health Organization recommendation that systems should aim to reduce DUP to three months or less, largely by fixing breakdowns in the pathway from early identification to initiation of specialty care.
This R34 FOA is designed to support developmental research and pilot work that helps communities understand and then improve how people move from first symptoms to appropriate early psychosis treatment. Projects funded under this mechanism are expected to do four main things: first, establish a baseline rate of DUP within real-world community treatment systems that already include evidence-based specialty care programs for FEP; second, map the actual referral pathways people take (for example, schools, primary care, emergency departments, community mental health clinics, juvenile justice, family-initiated contacts, and other entry points) to reach FEP specialty services; third, identify specific gaps and bottlenecks in those pathways that create delays or lead to missed referrals and disengagement; and fourth, develop and pilot test practical, feasible strategies intended to substantially reduce DUP for people experiencing FEP. In plain terms, the NIH is funding communities to measure how long delays are, figure out exactly where and why the delays happen, and then test workable fixes that could be scaled.
From an administrative standpoint, this is a discretionary NIH grant in the health category, under CFDA 93.242 (Mental Health Research Grants), using the R34 funding instrument. The FOA listed an estimated total funding amount of $2,000,000 and an award ceiling of $225,000, with no cost-sharing or matching requirement. It was posted April 10, 2013, with an original and final closing date of May 7, 2016, and an archive date of June 7, 2016, meaning it is no longer active but remains a useful template for understanding NIH priorities in early psychosis systems research and pilot intervention development.
Eligibility was broad across public and private sectors and included state and local governments (including county and city or township governments), public and private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations other than small businesses, small businesses, independent school districts, special district governments, public housing authorities/Indian housing authorities, and Native American tribal governments and organizations (including federally recognized tribes). The FOA also explicitly included many mission-driven institutional types such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply, although foreign components as defined in the NIH Grants Policy Statement were allowed.
Overall, the opportunity is aimed at accelerating early psychosis care by treating delayed access as a system problem that can be measured, mapped, and improved. Rather than funding large definitive trials right away, the R34 mechanism emphasizes groundwork: establishing baseline DUP in existing service systems, clarifying how referrals actually happen in practice, pinpointing where time is lost, and piloting targeted strategies to shorten the time from first symptoms to entry into evidence-based specialty FEP programs.
Frequently Asked Questions (FAQs)
What is the NIH funding opportunity PAR-13-188?
PAR-13-188 is an NIH funding opportunity announcement (FOA) titled "Reducing the Duration of Untreated Psychosis in the United States (R34)." It supports developmental research and pilot work aimed at reducing the time it takes for adolescents and young adults experiencing a first episode of psychosis (FEP) to reach adequate, evidence-based specialty care.
What does "duration of untreated psychosis (DUP)" mean in this FOA?
DUP refers to the time between the onset of psychotic symptoms and the start of adequate treatment. The FOA highlights that in the United States this delay commonly ranges from one to three years.
Why is reducing DUP a priority in this opportunity?
The FOA is based on consistent research findings that outcomes tend to be better when treatment begins close to symptom onset. Long delays can allow symptoms, disability, and disruptions to school, work, and social functioning to accumulate before someone enters a program designed for early psychosis care.
Who is the main population of concern for this FOA?
The FOA focuses on adolescents and young adults experiencing a first episode of psychosis (FEP). It notes that an estimated 100,000 adolescents and young adults in the U.S. experience a first episode of psychosis each year.
What is meant by the "first episode of psychosis (FEP)" in this context?
Within this FOA, FEP refers to the earliest phase of psychotic illness, which is widely viewed as a uniquely important window for timely, phase-specific care that may improve long-term clinical and functional trajectories.
What kinds of programs does the FOA refer to when it mentions specialty FEP care?
The FOA references specialty, multi-component programs designed to treat early psychosis. These programs have shown benefits for clinical symptoms and day-to-day functioning, but the FOA emphasizes that these benefits are harder to achieve when referrals are late or when individuals disengage early.
What benchmark does the FOA mention for an appropriate DUP target?
The FOA aligns with a World Health Organization recommendation that systems should aim to reduce DUP to three months or less, primarily by improving the pathway from early identification to initiation of specialty care.
What is the main goal of PAR-13-188?
The main goal is to treat delayed access to effective early psychosis care as a systems problem that can be measured, mapped, and improved. The FOA supports efforts to understand real-world delays and pilot practical strategies that can substantially reduce DUP.
What type of grant mechanism is used for this opportunity?
This opportunity uses the NIH R34 funding mechanism, which is intended for developmental research and pilot work rather than large definitive trials.
What are the four main activities projects are expected to do under this R34 FOA?
Projects are expected to: (1) establish a baseline rate of DUP within real-world community treatment systems that already include evidence-based specialty care programs for FEP; (2) map the referral pathways people take to reach FEP specialty services; (3) identify gaps and bottlenecks that create delays or missed referrals/disengagement; and (4) develop and pilot test feasible strategies intended to substantially reduce DUP for people experiencing FEP.
What does it mean to "establish a baseline rate of DUP" in a community system?
It means measuring how long the delay currently is, in practice, between symptom onset and the start of adequate treatment within real-world community treatment systems that already include evidence-based specialty FEP programs.
What does "mapping referral pathways" involve according to the FOA?
It involves documenting the actual routes people take from first symptoms to specialty FEP services. The FOA provides examples of possible entry points, such as schools, primary care, emergency departments, community mental health clinics, juvenile justice, and family-initiated contacts, among others.
What kinds of system problems is the FOA trying to uncover?
The FOA focuses on identifying gaps and bottlenecks in real-world pathways that cause delays, missed referrals, or disengagement before an individual successfully enters specialty FEP care.
What does the FOA mean by "pilot testing practical, feasible strategies"?
It refers to developing and trying out workable solutions within communities to shorten the time from the onset of psychotic symptoms to initiation of appropriate specialty care, with an emphasis on strategies that could be scaled or used more broadly if effective.
Does the FOA fund large-scale clinical trials?
Not as its primary emphasis. The R34 mechanism described in the FOA prioritizes groundwork and pilot work, such as baseline measurement, pathway mapping, bottleneck identification, and initial testing of targeted strategies.
What agency and category is this grant associated with?
It is an NIH discretionary grant in the health category.
What is the CFDA number associated with this opportunity?
The FOA is listed under CFDA 93.242, Mental Health Research Grants.
How much total funding was estimated for the FOA?
The FOA listed an estimated total funding amount of $2,000,000.
What was the award ceiling for individual awards?
The award ceiling was $225,000.
Was cost-sharing or matching required?
No. The FOA states there was no cost-sharing or matching requirement.
When was the FOA posted, and what were the closing dates?
It was posted April 10, 2013. The original and final closing date was May 7, 2016.
Is PAR-13-188 still active?
No. The FOA has an archive date of June 7, 2016, meaning it is no longer active.
If it is archived, why might PAR-13-188 still matter?
Even though it is no longer active, the FOA can still serve as a useful template for understanding NIH priorities related to early psychosis systems research and pilot intervention development focused on reducing delays in access to specialty care.
Who was eligible to apply?
Eligibility was broad and included many public and private organizations such as state and local governments, public and private higher education institutions, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, independent school districts, special district governments, public housing authorities/Indian housing authorities, and Native American tribal governments and organizations (including federally recognized tribes).
Did the FOA specifically include certain institution types (like minority-serving institutions)?
Yes. It explicitly included institution types such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, and it also referenced faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
Were non-U.S. (foreign) institutions eligible to apply?
No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply.
Were any foreign-related elements allowed at all?
Yes. The FOA notes that foreign components, as defined in the NIH Grants Policy Statement, were allowed.
What kinds of community settings and entry points does the FOA consider relevant for reducing DUP?
The FOA points to multiple real-world entry points that may influence how quickly someone reaches specialty care, including schools, primary care, emergency departments, community mental health clinics, juvenile justice, family-initiated contacts, and other pathways.
What is the overall approach encouraged by this FOA?
The FOA encourages communities to (1) measure how long delays are, (2) map exactly where people go for help and how referrals occur, (3) identify where time is lost or referrals fail, and (4) pilot targeted fixes intended to shorten time to entry into evidence-based specialty FEP programs.
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