Opportunity Information: Apply for PAR 12 199
Apply for PAR 12 199
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Research Education Grants for Statistical and Computational Training in the Genetics of Addiction (R25)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jun 8, 2012 and posted on Jun 8, 2012.
- Applicants must submit their applications by Aug 21, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: City or township governments For profit organizations other than small businesses Small businesses Independent school districts Special district governments Native American tribal governments (Federally recognized) County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Research Education Grants for Statistical and Computational Training in the Genetics of Addiction (R25) funding opportunity (PAR-12-199) is a National Institutes of Health (NIH) discretionary grant designed to strengthen the research education pipeline in a very specific area: the use of statistical and computational modeling approaches to solve genetics-based problems in addiction research. In practice, this program is meant to support structured educational experiences that help trainees build the quantitative and computational skill sets needed to analyze and interpret genetic and genomic data related to substance use disorders and addiction biology. The focus is on research education rather than on funding a traditional hypothesis-driven research project, so proposed activities are expected to emphasize training, curriculum development, mentored research experiences, workshops, or other organized educational components that directly improve participant competence in statistical genetics, computational genomics, and closely related analytic methods that are central to modern addiction genetics.
A key feature of this opportunity is its emphasis on interdisciplinarity and workforce development. Addiction genetics increasingly relies on complex data types and large-scale studies, including genome-wide association studies, sequencing, integrative multi-omics, and the modeling of gene-environment interplay. The R25 mechanism is intended to help institutions and organizations create or expand programs that teach the modeling, computing, and quantitative reasoning necessary to work effectively in that environment. Competitive programs under this announcement would typically be expected to describe a coherent educational plan, identify qualified faculty or mentors with relevant expertise, outline the trainee population to be served, and present clear learning objectives and evaluation approaches to show that participants will gain measurable skills in statistical and computational methods applied to addiction-related genetics questions.
The opportunity allows for participation by individuals at multiple career stages, including undergraduate students, graduate students, and postdoctoral trainees. Importantly, the eligible participant pool is not limited to U.S. citizens; the announcement explicitly notes that participants may include both U.S. and non-U.S. citizens. This flexibility can be helpful for programs that draw from diverse trainee populations already present at U.S.-based institutions. However, while non-U.S. citizens may participate as trainees, the applicant organizations themselves must meet NIH eligibility rules described in the announcement, which restrict who can apply for the award.
Eligibility to apply as an organization is broad and includes many types of U.S.-based entities. Eligible applicants listed in the source information include public and state-controlled institutions of higher education and private institutions of higher education, as well as a range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and certain public housing authorities/Indian housing authorities. The announcement also allows applications from nonprofit organizations, including those with 501(c)(3) status and those without 501(c)(3) status (in both cases, other than institutions of higher education), and from for-profit organizations (including small businesses and other for-profit organizations that are not small businesses). Additional categories called out as eligible include faith-based or community-based organizations, regional organizations, and certain education-focused institutions serving specific populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. The listing also references eligible agencies of the federal government and U.S. territories or possessions. At the same time, the announcement is clear that non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In other words, the training program must be proposed and administered by an eligible U.S.-based applicant organization, even though the trainees supported through the program may include non-U.S. citizens.
From an administrative and timing perspective, the opportunity is categorized as discretionary and uses the grant funding instrument type under the education and health funding activity category. It is associated with CFDA number 93.279 (Drug Abuse and Addiction Research Programs), reflecting its alignment with NIH-supported addiction research priorities. The posting date and creation date were June 8, 2012, with an original and current closing date of August 21, 2014, and an archive date of September 21, 2014, indicating that this specific announcement is no longer active as a current open competition. The opportunity does not require cost sharing or matching, which generally lowers the barrier to entry for organizations that might otherwise struggle to provide non-federal matching funds.
For applicants trying to understand what NIH is looking for through this R25, the central idea is capacity-building: creating a structured educational environment that reliably produces trainees who can handle modern statistical and computational demands in addiction genetics. That often means integrating quantitative coursework or modules with hands-on analysis of real genetics datasets, emphasizing reproducible computing practices, and providing mentored experiences that connect methods to addiction-relevant scientific questions. Programs typically benefit from demonstrating strong mentorship, access to appropriate computational resources, thoughtful recruitment and retention strategies for trainees, and a credible plan to evaluate outcomes, such as skill acquisition, subsequent research engagement, publications, conference presentations, or progression into addiction genetics or related quantitative biomedical research careers.
The administering agency is NIH, and the full announcement was made available through the NIH grants guide page referenced in the additional information link: http://grants.nih.gov/grants/guide/pa-files/PAR-12-199.html. The contact information provided in the source data points to the NIH Office of Extramural Research (OER) webmaster emails for technical issues accessing or linking to the announcement (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
What is the Research Education Grants for Statistical and Computational Training in the Genetics of Addiction (R25) opportunity?
This opportunity (PAR-12-199) is an NIH discretionary grant using the R25 research education mechanism. It is designed to strengthen the research education pipeline specifically for statistical and computational training applied to genetics-based problems in addiction research.
What is the main purpose of this R25 program?
The core purpose is capacity-building through research education. The program supports structured educational experiences that help trainees build quantitative and computational skill sets to analyze and interpret genetic and genomic data related to substance use disorders and addiction biology.
Is this funding meant for a traditional hypothesis-driven research project?
No. The emphasis is on research education rather than funding a traditional hypothesis-driven research project. Proposed activities are expected to focus on training and organized educational components that improve participant competence in statistical genetics, computational genomics, and closely related analytic methods used in addiction genetics.
What kinds of activities are appropriate under this opportunity?
Examples of appropriate activities include curriculum development, mentored research experiences, workshops, training modules, and other organized educational components that directly build skills in statistical and computational modeling approaches relevant to addiction genetics.
What scientific and technical areas does the program emphasize?
The program emphasizes statistical and computational modeling approaches for modern addiction genetics, including working with large-scale and complex data types such as genome-wide association studies, sequencing, integrative multi-omics, and modeling gene-environment interplay.
Who can participate as trainees in supported programs?
The opportunity allows trainees at multiple career stages, including undergraduate students, graduate students, and postdoctoral trainees.
Do trainees need to be U.S. citizens or permanent residents?
No. The announcement explicitly notes that participants may include both U.S. and non-U.S. citizens.
Can foreign (non-U.S.) institutions apply for this award?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply.
Are non-domestic components of U.S. organizations eligible to apply?
No. Non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed as part of an application?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
What types of organizations are eligible to apply?
Eligible applicants include a broad range of U.S.-based entities, including public and state-controlled institutions of higher education, private institutions of higher education, and multiple government entities (state governments, county governments, city or township governments, special district governments, independent school districts, and certain public housing authorities/Indian housing authorities). Eligibility also includes nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education) and for-profit organizations (including small businesses and other for-profit organizations that are not small businesses). Additional eligible categories include faith-based or community-based organizations, regional organizations, eligible agencies of the federal government, and U.S. territories or possessions.
Are minority-serving institutions specifically mentioned as eligible applicants?
Yes. The eligible applicant listing specifically references Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Does this opportunity require cost sharing or matching funds?
No. The opportunity does not require cost sharing or matching.
What is the administering agency for this grant?
The administering agency is the National Institutes of Health (NIH).
What funding instrument type and activity category are associated with this opportunity?
The opportunity uses the grant funding instrument type and falls under the education and health funding activity category.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.279, Drug Abuse and Addiction Research Programs.
Is this funding opportunity still open?
No. The posting and creation date were June 8, 2012, and the original and current closing date listed is August 21, 2014, with an archive date of September 21, 2014. This indicates the specific announcement is no longer active as a current open competition.
What is NIH looking for in a competitive program under this announcement?
Competitive programs would typically be expected to present a coherent educational plan, identify qualified faculty or mentors with relevant expertise, define the trainee population to be served, and provide clear learning objectives and evaluation approaches demonstrating measurable skill gains in statistical and computational methods applied to addiction-related genetics questions.
What kinds of outcomes or evaluation approaches are mentioned?
The description highlights the importance of evaluation and outcome tracking, such as measuring skill acquisition and documenting subsequent research engagement, publications, conference presentations, or progression into addiction genetics or related quantitative biomedical research careers.
What program elements are suggested as beneficial for demonstrating program strength?
Suggested strengths include strong mentorship, access to appropriate computational resources, thoughtful recruitment and retention strategies for trainees, hands-on analysis of real genetics datasets, and emphasis on reproducible computing practices connected to addiction-relevant scientific questions.
Where can the full announcement be found?
The full announcement is available via the NIH Grants Guide page: http://grants.nih.gov/grants/guide/pa-files/PAR-12-199.html.
Who is listed as the contact for technical issues accessing or linking to the announcement?
The contact information provided points to the NIH Office of Extramural Research (OER) webmaster emails for technical issues: FBOWebmaster@OD.NIH.GOV.
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