Opportunity Information: Apply for PA 12 142

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on Emergency Medical Services for Children (EMSC) R21" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.361 Nursing Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Mar 29, 2012 and posted on Mar 29, 2012.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities For profit organizations other than small businesses State governments County governments City or township governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Research on Emergency Medical Services for Children (EMSC) R21 opportunity (Funding Opportunity Number PA-12-142) was a National Institutes of Health (NIH) discretionary grant announcement aimed at strengthening and expanding the research base for pediatric emergency care. The central purpose was to improve how emergency care is delivered to children so that injuries and acute illnesses lead to fewer deaths and fewer long-term health problems. In practice, the FOA targeted studies that could lead to better systems, better clinical decisions, and better outcomes for children who need urgent or emergency medical attention.

This FOA specifically called for innovative, exploratory, and developmental projects using the NIH R21 mechanism. R21 grants are typically used to support early-stage ideas, pilot studies, proof-of-concept work, feasibility testing, or the development of new approaches that can later be scaled into larger research programs. Within the EMSC focus, NIH was looking for projects that push the field forward even if they are not yet fully mature or supported by extensive preliminary data, as long as the ideas are strong and the proposed work is rigorous and well-justified.

The announcement highlighted several broad research areas under the umbrella of EMSC. One area was prevention research designed to reduce the need for emergency care in the first place, such as strategies that prevent injuries, reduce acute exacerbations of chronic conditions, or address upstream factors that commonly lead children into emergency settings. Another major area was clinical research to ensure children receive high-quality and appropriate emergency medical, nursing, and mental health care, recognizing that pediatric emergencies include behavioral health crises as well as medical and traumatic events. The FOA also emphasized health systems research across the entire continuum of emergency care, including pre-hospital care (for example, EMS and transport), care in the emergency department, transition into inpatient care when necessary, and safe discharge planning and return to the community. Alongside quality and outcomes, the announcement also explicitly welcomed models that improve service delivery and cost efficiency in pediatric emergency care, reflecting an interest in both clinical effectiveness and operational performance.

A notable component of the FOA was the encouragement of methodological studies that improve the quality of research conducted in pediatric emergency contexts. Pediatric emergency research often faces practical and ethical complexities such as time-sensitive decision-making, consent challenges, low-frequency high-acuity events, heterogeneous patient populations, and outcomes that may be rare but critical. By inviting methodological work, NIH signaled that building better tools, study designs, measurement strategies, data systems, and analytic approaches was considered an important pathway to producing stronger evidence in EMSC overall.

From an administrative and eligibility standpoint, the opportunity was posted on March 29, 2012, with an original and final closing date of May 7, 2015, and an archive date of June 7, 2015, meaning it is no longer open for application. The award ceiling listed was $200,000. The FOA indicated there was no cost sharing or matching requirement, which typically reduces barriers for applicants and allows budgets to be driven by project needs rather than required institutional contributions.

Eligibility was broad and included many types of organizations that could contribute to pediatric emergency research. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), independent school districts, special district governments, city/county/state governments, tribal governments and tribal organizations (including federally recognized and other tribal entities), public housing authorities/Indian housing authorities, regional organizations, and for-profit organizations (excluding small businesses in the listed category, though small businesses were also included separately as eligible). The FOA also listed several specific categories often highlighted in NIH opportunities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Importantly, the announcement stated that non-U.S. entities (foreign institutions) were eligible to apply, non-U.S. components of U.S. organizations were eligible, and foreign components as defined by NIH policy were allowed, which broadened the potential for international collaboration and research in pediatric emergency care systems.

The funding activity categories associated with the opportunity were Education, Health, Income Security, and Social Services, and the CFDA numbers listed were 93.242 (Mental Health Research Grants), 93.361 (Nursing Research), and 93.865 (Child Health and Human Development Extramural Research). That mix reflects the interdisciplinary nature of EMSC research, spanning pediatric medicine, emergency care delivery, nursing practice, mental and behavioral health, and child development considerations, all within real-world emergency systems.

For reference, the FOA’s official NIH posting was linked at http://grants.nih.gov/grants/guide/pa-files/PA-12-142.html, and the contact provided for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the Research on Emergency Medical Services for Children (EMSC) R21 opportunity (PA-12-142)?

PA-12-142 was a National Institutes of Health (NIH) discretionary grant announcement that used the NIH R21 mechanism to support innovative, exploratory, and developmental research in pediatric emergency care. Its overall aim was to strengthen and expand the research base for Emergency Medical Services for Children (EMSC).

What was the main purpose of this funding opportunity?

The central purpose was to improve how emergency care is delivered to children so that injuries and acute illnesses lead to fewer deaths and fewer long-term health problems. The FOA focused on studies that could improve systems, clinical decisions, and outcomes for children needing urgent or emergency medical attention.

What type of grant mechanism did this FOA use?

This opportunity used the NIH R21 mechanism, which is intended for innovative, exploratory, and developmental projects such as early-stage ideas, pilot studies, proof-of-concept work, feasibility testing, or the development of new approaches that could later be expanded into larger research programs.

Does an R21 project need extensive preliminary data?

The FOA emphasized projects that push the field forward even if they are not yet fully mature or supported by extensive preliminary data, provided that the ideas are strong and the proposed work is rigorous and well-justified.

What kinds of pediatric emergency research topics were encouraged?

The announcement highlighted broad areas under EMSC, including prevention research, clinical research (including medical, nursing, and mental health care), health systems research across the emergency care continuum, and studies that improve service delivery and cost efficiency in pediatric emergency care.

What is meant by prevention research in this FOA?

Prevention research referred to strategies designed to reduce the need for emergency care in the first place, such as preventing injuries, reducing acute exacerbations of chronic conditions, or addressing upstream factors that commonly lead children into emergency settings.

Did the FOA include mental and behavioral health emergencies?

Yes. The FOA explicitly recognized that pediatric emergencies include behavioral health crises as well as medical and traumatic events, and it encouraged research that supports high-quality and appropriate emergency medical, nursing, and mental health care.

What parts of the emergency care system were included in the health systems research focus?

The FOA emphasized health systems research across the full continuum of emergency care, including pre-hospital care (such as EMS and transport), care in the emergency department, transitions into inpatient care when needed, and safe discharge planning and return to the community.

Was research on improving efficiency and costs allowed?

Yes. Alongside quality and outcomes, the announcement explicitly welcomed models that improve service delivery and cost efficiency in pediatric emergency care, reflecting interest in both clinical effectiveness and operational performance.

What were the methodological research priorities mentioned in the FOA?

A notable component was the encouragement of methodological studies that improve the quality of research in pediatric emergency contexts. This included developing better tools, study designs, measurement strategies, data systems, and analytic approaches for EMSC research.

Why did NIH encourage methodological studies for pediatric emergency research?

The FOA noted that pediatric emergency research can involve practical and ethical complexities such as time-sensitive decision-making, consent challenges, low-frequency high-acuity events, heterogeneous patient populations, and outcomes that may be rare but critical. Methodological improvements were positioned as a way to produce stronger evidence across EMSC research.

When was PA-12-142 posted, and is it still open?

The opportunity was posted on March 29, 2012. The original and final closing date was May 7, 2015, and the archive date was June 7, 2015. Based on those dates, it is no longer open for application.

What was the maximum award amount listed for this opportunity?

The award ceiling listed in the FOA was $200,000.

Was cost sharing or matching required?

No. The FOA indicated there was no cost sharing or matching requirement.

What types of organizations were eligible to apply?

Eligibility was broad. The FOA listed eligible applicants including public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), independent school districts, special district governments, city/county/state governments, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, regional organizations, and for-profit organizations. Small businesses were also included as eligible.

Were minority-serving and community-based institutions included in eligibility?

Yes. The FOA specifically listed categories commonly highlighted in NIH opportunities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Could foreign (non-U.S.) organizations apply?

Yes. The announcement stated that non-U.S. entities (foreign institutions) were eligible to apply. It also stated that non-U.S. components of U.S. organizations were eligible, and that foreign components (as defined by NIH policy) were allowed.

What funding activity categories were associated with this FOA?

The funding activity categories associated with the opportunity were Education, Health, Income Security, and Social Services.

What CFDA numbers were listed for this opportunity?

The CFDA numbers listed were 93.242 (Mental Health Research Grants), 93.361 (Nursing Research), and 93.865 (Child Health and Human Development Extramural Research).

Where can the official NIH posting for PA-12-142 be found?

The FOA’s official NIH posting was linked at http://grants.nih.gov/grants/guide/pa-files/PA-12-142.html.

Who was listed as the contact for access or linking issues?

The contact provided for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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