Opportunity Information: Apply for PA 12 141

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on Emergency Medical Services for Children (EMSC) R01" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.361 Nursing Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Mar 29, 2012 and posted on Mar 29, 2012.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Private institutions of higher education Special district governments Small businesses State governments City or township governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Research on Emergency Medical Services for Children (EMSC) R01 opportunity (Funding Opportunity Number PA-12-141) was a National Institutes of Health (NIH) discretionary grant program intended to expand and strengthen research focused on emergency care for infants, children, and adolescents. The core purpose of the announcement was to improve both the quality and the volume of pediatric emergency care research, ultimately aiming to reduce illness complications (morbidity) and prevent deaths (mortality) among children by improving how emergency care is delivered across settings.

The FOA cast a wide net in terms of the kinds of studies it wanted to support, using the umbrella term "EMSC research" to include several major categories. One area was prevention-focused research, meaning studies that identify strategies, interventions, or systems changes that can reduce injuries, acute events, and other conditions that lead children to need emergency care in the first place. Another major area was clinical research in emergency contexts, aimed at ensuring children receive timely, appropriate, and high-quality medical, nursing, and mental health care when emergencies happen. This includes research on diagnosis, treatment decisions, protocols, and care pathways that are tailored to pediatric needs rather than simply adapted from adult emergency care.

A major emphasis of the opportunity was health systems research that spans the full continuum of emergency care, not just what happens inside an emergency department. This includes pre-hospital care (such as EMS response, triage, transport decisions, and coordination with receiving facilities), emergency department processes (including staffing models, pediatric readiness, clinical workflows, and safety practices), inpatient transitions (admissions from the ED, critical care, hospital-based pediatric services), and the return to the community (discharge planning, follow-up care, coordination with primary care and community services, and reducing avoidable return visits). The FOA also encouraged models and studies focused on improving service delivery and cost efficiency in pediatric emergency care, recognizing that better outcomes often depend on how care is organized, financed, and implemented at scale. In addition, it explicitly welcomed methodological research designed to improve the quality of EMSC research itself, such as better study designs, improved measurement approaches, enhanced data collection methods, and tools that strengthen rigor and reproducibility in pediatric emergency settings.

From an administrative standpoint, this was an NIH R01 grant mechanism, which typically supports mature, hypothesis-driven projects with clear aims and a defined research plan. It was listed under multiple CFDA numbers reflecting its intersection with mental health research (93.242), nursing research (93.361), and child health and human development research (93.865). The program did not require cost sharing or matching funds, which generally lowers barriers for applicants who may not have access to significant institutional co-funding.

Eligibility was broad and included many types of organizations. Domestic applicants could include public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), state and local governments (including county, city/township, and special district governments), small businesses, and for-profit organizations other than small businesses. Tribal entities were also eligible, including federally recognized tribal governments and other tribal organizations. The FOA also identified additional eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, U.S. territories or possessions, and regional organizations. Notably, foreign involvement was allowed: non-U.S. entities (foreign organizations and foreign institutions) could apply, non-U.S. components of U.S. organizations were eligible, and foreign components were permitted as defined in the NIH Grants Policy Statement, which can be important for projects involving international collaborations or comparative systems research.

The opportunity was posted and created on March 29, 2012, with an original and final closing date of May 7, 2015, and it was archived on June 7, 2015. Applicants and interested parties were directed to the full announcement on the NIH grants website (http://grants.nih.gov/grants/guide/pa-files/PA-12-141.html). For access or technical issues related to the online announcement, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Overall, this FOA supported research meant to make pediatric emergency care safer, more effective, more coordinated across the full emergency-care pathway, and more evidence-based, while also pushing the field toward stronger research methods and better implementation of what works in real-world emergency settings.

Frequently Asked Questions (FAQs): Research on Emergency Medical Services for Children (EMSC) R01 (PA-12-141)

What is the Research on Emergency Medical Services for Children (EMSC) R01 opportunity?

This was a National Institutes of Health (NIH) discretionary grant opportunity using the R01 mechanism (Funding Opportunity Number PA-12-141). It was intended to expand and strengthen research focused on emergency care for infants, children, and adolescents.

What was the main goal of this funding opportunity?

The core purpose was to improve both the quality and the volume of pediatric emergency care research, with the ultimate aim of reducing complications (morbidity) and preventing deaths (mortality) among children by improving how emergency care is delivered across settings.

What kinds of research did the FOA consider "EMSC research"?

The announcement used "EMSC research" as an umbrella term that included prevention-focused research, clinical research in emergency contexts, health systems research spanning the full emergency care continuum, cost and service-delivery improvement studies, and methodological research to strengthen the quality of EMSC research itself.

Did the FOA support prevention-focused research?

Yes. It included prevention-focused research aimed at identifying strategies, interventions, or system changes that can reduce injuries, acute events, and other conditions that lead children to require emergency care.

Did the FOA support clinical research in emergency settings?

Yes. The FOA supported clinical research intended to ensure children receive timely, appropriate, and high-quality medical, nursing, and mental health care during emergencies, including research on diagnosis, treatment decisions, protocols, and pediatric-specific care pathways.

Was there an emphasis on research beyond the emergency department?

Yes. A major emphasis was health systems research across the full continuum of emergency care, not limited to the emergency department.

What parts of the emergency care continuum were included?

The FOA described a continuum that included pre-hospital care (EMS response, triage, transport decisions, coordination with receiving facilities), emergency department processes (staffing models, pediatric readiness, workflows, safety practices), inpatient transitions (admissions from the ED, critical care, hospital-based pediatric services), and return to the community (discharge planning, follow-up, coordination with primary care and community services, reducing avoidable return visits).

Did the FOA encourage studies on how pediatric emergency care is organized and financed?

Yes. It encouraged models and studies focused on improving service delivery and cost efficiency in pediatric emergency care, recognizing that outcomes can depend on how care is organized, financed, and implemented at scale.

Did the FOA include support for methodological research?

Yes. It explicitly welcomed methodological research aimed at improving the quality of EMSC research, such as better study designs, improved measurement approaches, enhanced data collection methods, and tools to strengthen rigor and reproducibility in pediatric emergency settings.

What grant mechanism was used?

This opportunity used the NIH R01 mechanism, which typically supports mature, hypothesis-driven projects with clear aims and a defined research plan.

Which CFDA numbers were associated with this opportunity?

The FOA was listed under multiple CFDA numbers: 93.242 (mental health research), 93.361 (nursing research), and 93.865 (child health and human development research).

Was cost sharing or matching required?

No. The program did not require cost sharing or matching funds.

Who was eligible to apply (domestic organizations)?

Eligibility was broad and included public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3)), state and local governments (including county, city/township, and special district governments), small businesses, and for-profit organizations other than small businesses.

Were tribal entities eligible?

Yes. Eligible applicants included federally recognized tribal governments and other tribal organizations.

Were specific institution types called out as eligible?

Yes. The FOA identified additional eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, U.S. territories or possessions, and regional organizations.

Could foreign organizations or international components participate?

Yes. Foreign involvement was allowed. Non-U.S. entities (foreign organizations and foreign institutions) could apply; non-U.S. components of U.S. organizations were eligible; and foreign components were permitted as defined in the NIH Grants Policy Statement.

When was the opportunity posted and when did it close?

The opportunity was posted and created on March 29, 2012. The original and final closing date was May 7, 2015.

Is this funding opportunity still active?

No. It was archived on June 7, 2015.

Where could applicants find the full announcement?

Applicants were directed to the NIH grants website at: http://grants.nih.gov/grants/guide/pa-files/PA-12-141.html

Who was listed as the contact for access or technical issues with the online announcement?

The contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

How did the FOA define the intended impact on pediatric emergency care?

Overall, it supported research intended to make pediatric emergency care safer, more effective, more coordinated across the full emergency-care pathway, and more evidence-based, while also encouraging stronger research methods and better implementation of effective practices in real-world emergency settings.

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