Opportunity Information: Apply for PA 15 028
Apply for PA 15 028
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Research on Eosinophil Associated Disorders (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Jan 12, 2015 and posted on Oct 31, 2014.
- Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $275,000.00 in funding.
- Eligible applicants include: City or township governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Independent school districts Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses County governments Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Research on Eosinophil Associated Disorders (R21) opportunity (Funding Opportunity Number PA-15-028) is an NIH discretionary grant program designed to spur exploratory, early-stage studies that deepen understanding of eosinophil-associated disorders. The central goal is to support research that clarifies disease pathophysiology and maps the cellular and molecular mechanisms by which eosinophil leukocytes contribute to these conditions. In practical terms, the FOA is aimed at helping investigators test new concepts, generate preliminary data, and explore promising mechanistic leads that can later be expanded into larger, more definitive projects.
This announcement uses the NIH R21 mechanism, which is specifically built for exploratory and developmental research. That framing signals an emphasis on innovation and feasibility testing rather than fully mature, long-term research programs. Projects supported under this FOA are expected to focus on conceptual or early experimental stages, such as uncovering previously unappreciated pathways, developing or applying emerging tools to eosinophil biology, or probing mechanistic hypotheses about how eosinophils drive or modulate disease processes. The scientific scope is centered on eosinophil biology in disease, including how these cells influence inflammation, tissue remodeling, immune regulation, and other downstream effects relevant to eosinophil-associated disorders.
The sponsoring agency is the National Institutes of Health. The announcement is linked to multiple NIH-related program areas as reflected by the CFDA numbers provided, including 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research), 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research). This mix indicates the FOA is intentionally cross-cutting and can accommodate eosinophil-relevant questions across different organ systems and disease categories, such as allergic disease, immune-mediated conditions, infections, and inflammatory disorders that involve eosinophils.
From a funding standpoint, the opportunity lists an award ceiling of $275,000, and it explicitly states there is no cost sharing or matching requirement. The instrument type is a grant. While the detailed budget structure and project period rules are defined in the full FOA, the information provided here communicates that applicants should plan proposals consistent with an R21-scale exploratory project and within the stated ceiling.
Eligibility is broad and includes a wide range of domestic applicants, such as state and local governments (including city or township governments, county governments, and special district governments), independent school districts, public housing authorities/Indian housing authorities, and many nonprofit and higher education entities (public and state-controlled universities, private universities, and nonprofits with or without 501(c)(3) status, excluding institutions of higher education in the “nonprofit without 501(c)(3)†category as written). For-profit entities are eligible as well, including small businesses and other for-profit organizations. The FOA also allows participation from tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, as well as tribally controlled colleges and universities.
The eligibility language also makes clear that non-U.S. participation is allowed. Non-domestic (non-U.S.) entities and foreign institutions are eligible to apply, non-domestic components of U.S. organizations may apply, and foreign components are permitted consistent with NIH policy definitions. The FOA further highlights inclusivity for institutions and organizations such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, and eligible federal government agencies.
Key dates show the FOA was posted on October 31, 2014, created on January 12, 2015, and ultimately archived on February 7, 2018. The original closing date is listed as May 7, 2018, with a current closing date of January 7, 2018, indicating the active submission window has ended and the opportunity is no longer open for new applications under this specific announcement as provided. For the authoritative program text, requirements, and any related reissued opportunities, the FOA directs applicants to the full notice at http://grants.nih.gov/grants/guide/pa-files/PA-15-028.html.
For technical issues accessing the announcement or linking problems, the provided contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Research on Eosinophil Associated Disorders (R21) - NIH (PA-15-028)
What is the Research on Eosinophil Associated Disorders (R21) funding opportunity?
This opportunity (Funding Opportunity Number PA-15-028) is an NIH discretionary grant program intended to spur exploratory, early-stage research on eosinophil-associated disorders. It is designed to help investigators test new ideas, generate preliminary data, and explore mechanistic leads that could later be expanded into larger, more definitive projects.
What is the main scientific goal of this FOA?
The central goal is to deepen understanding of eosinophil-associated disorders by clarifying disease pathophysiology and mapping the cellular and molecular mechanisms through which eosinophil leukocytes contribute to these conditions.
Which grant mechanism does this opportunity use?
This announcement uses the NIH R21 mechanism, which is specifically intended for exploratory and developmental research. The R21 structure emphasizes innovation and feasibility testing rather than fully mature, long-term research programs.
What types of projects are a good fit for an R21 under this FOA?
Projects are expected to be at the conceptual or early experimental stage, such as uncovering previously unappreciated pathways, developing or applying emerging tools to eosinophil biology, or probing mechanistic hypotheses about how eosinophils drive or modulate disease processes.
What scientific topics and research scope does the FOA emphasize?
The scope centers on eosinophil biology in disease, including how eosinophils influence inflammation, tissue remodeling, immune regulation, and other downstream effects relevant to eosinophil-associated disorders.
Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Is this opportunity focused on a single disease area or is it cross-cutting?
It is explicitly cross-cutting. The CFDA numbers listed indicate relevance across multiple NIH-related program areas and disease categories, including allergic disease, immune-mediated conditions, infections, and inflammatory disorders that involve eosinophils.
Which CFDA program areas are associated with this FOA?
The CFDA numbers provided are 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research), 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research).
What is the funding instrument type?
The instrument type is a grant.
What is the maximum award amount (award ceiling) listed?
The opportunity lists an award ceiling of $275,000.
Is cost sharing or matching required?
No. The opportunity explicitly states there is no cost sharing or matching requirement.
Who is eligible to apply (in general terms)?
Eligibility is broad and includes many domestic applicant types across government, education, nonprofit, and for-profit sectors, as well as tribal entities and non-U.S. applicants as allowed by NIH policies described in the opportunity.
Are state and local governments eligible to apply?
Yes. The eligibility list includes state and local governments, including city or township governments, county governments, and special district governments.
Are independent school districts eligible to apply?
Yes. Independent school districts are listed as eligible.
Are public housing authorities eligible to apply?
Yes. Public housing authorities and Indian housing authorities are included in the eligible applicant types.
Are universities and colleges eligible to apply?
Yes. Eligibility includes higher education entities such as public and state-controlled universities, private universities, and tribally controlled colleges and universities.
Are nonprofit organizations eligible to apply?
Yes. Nonprofits are included, including nonprofits with or without 501(c)(3) status, with the eligibility language noting an exclusion related to the “nonprofit without 501(c)(3)†category as written (specifically excluding institutions of higher education in that category).
Are for-profit organizations eligible to apply?
Yes. For-profit entities are eligible, including small businesses and other for-profit organizations.
Are tribal governments and tribal organizations eligible?
Yes. The FOA allows participation from tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, and includes tribally controlled colleges and universities.
Does the FOA allow non-U.S. (foreign) applicants or components?
Yes. The eligibility language states that non-domestic (non-U.S.) entities and foreign institutions are eligible to apply, non-domestic components of U.S. organizations may apply, and foreign components are permitted consistent with NIH policy definitions.
Are minority-serving institutions and community-based organizations highlighted as eligible?
Yes. The opportunity highlights inclusivity for organizations such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly mentioned as eligible.
Are regional organizations eligible to apply?
Yes. Regional organizations are included in the eligibility language.
Are federal government agencies eligible?
Yes. Eligible federal government agencies are listed among eligible applicants.
When was this FOA posted and when was it created?
The FOA was posted on October 31, 2014, and created on January 12, 2015.
Is this funding opportunity still open for applications?
No. The opportunity is archived (archived on February 7, 2018), and the dates provided indicate the active submission window has ended for this specific announcement.
What closing dates are listed for this FOA?
The information provided lists an original closing date of May 7, 2018, and a current closing date of January 7, 2018. Based on the archived status and these dates, the opportunity is no longer open for new applications under this specific FOA as provided.
Where can applicants find the authoritative full announcement text and requirements?
The FOA directs readers to the full notice at http://grants.nih.gov/grants/guide/pa-files/PA-15-028.html for authoritative program text, requirements, and any related information.
Who should be contacted for technical issues accessing the announcement or link problems?
For technical issues accessing the announcement or linking problems, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is this FOA trying to enable investigators to do in practical terms?
In practical terms, it aims to help investigators test new concepts, generate preliminary data, and explore promising mechanistic leads in eosinophil biology and eosinophil-associated disorders, with the expectation that successful leads may be expanded into larger projects later.
Does the provided information describe the detailed budget structure or project period rules?
No. The provided summary notes that detailed budget structure and project period rules are defined in the full FOA, while emphasizing that applications should be consistent with an R21-scale exploratory project and within the stated award ceiling.
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