Opportunity Information: Apply for PA 13 369

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on the Health Determinants and Consequences of Violence and its Prevention, Particularly Firearm Violence (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.307 Minority Health and Health Disparities Research 93.313 NIH Office of Research on Womens Health 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Sep 27, 2013 and posted on Sep 27, 2013.
  • Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Public housing authorities/Indian housing authorities County governments Special district governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Small businesses City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The NIH funding opportunity PA 13-369, titled "Research on the Health Determinants and Consequences of Violence and its Prevention, Particularly Firearm Violence (R21)," was a discretionary grant program designed to support exploratory and early-stage studies on violence as a major public health issue. Using the R21 mechanism, the announcement aimed to catalyze innovative, shorter-term projects that can generate preliminary data, test new ideas, or build the groundwork for larger, definitive studies. The program explicitly framed violence research as spanning multiple NIH missions, encouraging interdisciplinary approaches that connect biological, behavioral, clinical, and community-level perspectives.

A central emphasis of the FOA was understanding both the determinants (risk and protective factors) and the consequences (health, mental health, and broader well-being impacts) of violence, along with research on prevention. It welcomed a wide spectrum of study types, including basic neuroscience and basic behavioral research that can clarify mechanisms linked to aggression, impulsivity, stress reactivity, trauma responses, and decision-making. It also invited clinical and translational research that bridges findings from fundamental science into practical clinical insights, such as identifying biomarkers, improving risk assessment, and refining pathways from exposure to violence toward physical injury, substance use, depression, PTSD, and other outcomes.

On the prevention side, the FOA supported intervention development at multiple levels, including individual, family, and community-based strategies. That could include designing and refining programs intended to prevent violence, reduce escalation, lessen harm, or strengthen resilience and protective environments. Beyond development work, the announcement also covered efficacy trials of interventions that are grounded in evidence from basic or translational research, meaning it was not limited to theory-building and could extend to testing whether a prevention approach actually produces measurable benefits under controlled conditions.

Another major component was dissemination and implementation research, reflecting the reality that even proven interventions often fail to reach the people and settings that need them most. The FOA therefore encouraged studies focused on how to deliver effective violence-prevention or harm-reduction strategies in real-world environments such as clinics, schools, community organizations, and justice-adjacent systems, including research on adoption, fidelity, sustainability, and barriers to scale. In practical terms, this meant applicants could propose work on the best ways to move evidence-based approaches from research contexts into routine practice.

While the FOA covered violence broadly, it stated that particular consideration would be given to applications focused on the intersection of firearms and different types of violence. This included homicide, suicide, youth and gang-related violence, and intimate partner violence, with firearms treated as a critical factor shaping lethality, risk pathways, and prevention opportunities. In effect, the announcement signaled NIH interest in studies that address firearm-related dynamics across multiple violence domains, whether through understanding causal mechanisms, identifying modifiable risk factors, evaluating intervention approaches, or improving implementation of effective strategies.

From an administrative standpoint, the opportunity was posted on September 27, 2013, and ultimately closed on January 7, 2017 (archived February 7, 2017). The listed award ceiling was $200,000. It did not require cost sharing or matching. The activity aligned with multiple CFDA program areas, including mental health, alcohol research, drug abuse and addiction research, minority health and health disparities, women’s health, and child health and human development, reflecting how violence intersects with substance use, developmental trajectories, disparities, and gender- and family-related health issues.

Eligibility was broad across U.S.-based organizations and government entities. Eligible applicants included nonprofit organizations (with and without 501(c)(3) status), public and private institutions of higher education, state and local governments (including counties, cities/townships, special districts), independent school districts, public housing authorities, tribal governments and tribal organizations, small businesses, and for-profit organizations other than small businesses. The FOA also clarified eligibility for a range of mission-driven institutions and community-based organizations, including HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. Foreign institutions were not eligible, and foreign components of U.S. organizations were not permitted under NIH policy as described in the announcement.

Overall, PA 13-369 was structured to stimulate practical, science-driven progress on violence prevention and the health impacts of violence, with a notable priority on firearm-related violence across contexts such as suicide, homicide, youth violence, gang-related violence, and intimate partner violence. The FOA encouraged applicants to integrate rigorous methods with real-world relevance, supporting everything from early mechanistic insights to intervention testing and strategies for getting effective approaches implemented at scale.

Frequently Asked Questions (FAQs)

What is the NIH funding opportunity PA 13-369?

PA 13-369 is an NIH funding opportunity announcement titled "Research on the Health Determinants and Consequences of Violence and its Prevention, Particularly Firearm Violence (R21)." It was a discretionary grant program intended to support research that treats violence as a major public health issue, with particular consideration for studies focused on firearm-related violence.

What grant mechanism does this opportunity use?

This opportunity used the NIH R21 mechanism, which is designed for exploratory and early-stage research. The intent was to support innovative, shorter-term projects that can generate preliminary data, test new ideas, or lay the groundwork for larger studies.

Is this funding opportunity still open?

No. The opportunity was posted on September 27, 2013, and closed on January 7, 2017. It was archived on February 7, 2017.

What is the maximum award amount (award ceiling) for this opportunity?

The listed award ceiling was $200,000.

Is cost sharing or matching required?

No. This funding opportunity did not require cost sharing or matching.

What kinds of research topics were supported?

The FOA supported research on both the determinants (risk and protective factors) and the consequences (health, mental health, and broader well-being impacts) of violence, as well as research focused on violence prevention.

How did the FOA define the overall scientific approach it wanted to encourage?

The FOA explicitly framed violence research as spanning multiple NIH missions and encouraged interdisciplinary approaches. It welcomed projects connecting biological, behavioral, clinical, and community-level perspectives.

Did the FOA support basic neuroscience and basic behavioral research?

Yes. It welcomed basic neuroscience and basic behavioral research intended to clarify mechanisms related to aggression, impulsivity, stress reactivity, trauma responses, and decision-making.

Did the FOA support clinical and translational research?

Yes. It invited clinical and translational research that bridges fundamental science into practical clinical insights, including work such as identifying biomarkers, improving risk assessment, and refining pathways linking violence exposure to outcomes like physical injury, substance use, depression, PTSD, and other impacts.

What types of prevention research were included?

The FOA supported intervention development at multiple levels, including individual, family, and community-based strategies. This could include designing and refining programs to prevent violence, reduce escalation, lessen harm, or strengthen resilience and protective environments.

Were efficacy trials allowed under this opportunity?

Yes. The announcement covered efficacy trials of interventions grounded in evidence from basic or translational research, meaning it could include controlled testing of whether a prevention approach produces measurable benefits.

Did the FOA encourage dissemination and implementation research?

Yes. A major component was dissemination and implementation research focused on how to deliver effective violence-prevention or harm-reduction strategies in real-world settings, including clinics, schools, community organizations, and justice-adjacent systems.

What kinds of implementation questions fit this FOA?

Examples explicitly highlighted by the FOA included research on adoption, fidelity, sustainability, and barriers to scaling evidence-based interventions, with the practical goal of moving effective approaches from research contexts into routine practice.

Was the opportunity limited only to firearm violence?

No. The FOA covered violence broadly, but it stated that particular consideration would be given to applications focused on the intersection of firearms and different types of violence.

What types of violence were specifically mentioned in connection with firearms?

The FOA noted firearm intersections with homicide, suicide, youth and gang-related violence, and intimate partner violence, emphasizing firearms as a factor shaping lethality, risk pathways, and prevention opportunities.

What kinds of firearm-related research angles were relevant?

Based on the FOA description, relevant angles included understanding causal mechanisms, identifying modifiable risk factors, evaluating intervention approaches, and improving implementation of effective strategies across multiple violence domains where firearms affect risk and outcomes.

Which organizations were eligible to apply?

Eligibility was broad for U.S.-based organizations and government entities. Eligible applicants included nonprofit organizations (with and without 501(c)(3) status), public and private institutions of higher education, state and local governments (including counties, cities/townships, special districts), independent school districts, public housing authorities, tribal governments and tribal organizations, small businesses, and for-profit organizations other than small businesses.

Did the FOA include special categories of eligible institutions?

Yes. The FOA clarified eligibility for a range of mission-driven and community-based institutions, including HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.

Are foreign institutions eligible to apply?

No. Foreign institutions were not eligible.

Are foreign components of U.S. organizations allowed?

No. The FOA stated that foreign components of U.S. organizations were not permitted under NIH policy as described in the announcement.

Which CFDA program areas did this opportunity align with?

The activity aligned with multiple CFDA program areas, including mental health, alcohol research, drug abuse and addiction research, minority health and health disparities, women’s health, and child health and human development.

Why did the FOA align with so many health program areas?

As described, the FOA emphasized that violence intersects with substance use, developmental trajectories, disparities, and gender- and family-related health issues, which maps to multiple NIH mission areas and CFDA program categories.

What was the overarching goal of PA 13-369?

Overall, PA 13-369 was structured to stimulate practical, science-driven progress on violence prevention and on understanding the health impacts of violence, with a notable priority on firearm-related violence across contexts such as suicide, homicide, youth violence, gang-related violence, and intimate partner violence.

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