Opportunity Information: Apply for PAR 14 065
Apply for PAR 14 065
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Jan 7, 2014 and posted on Jan 7, 2014.
- Applicants must submit their applications by Apr 10, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments Private institutions of higher education For profit organizations other than small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Public housing authorities/Indian housing authorities Independent school districts Public and State controlled institutions of higher education City or township governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The funding opportunity titled "Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3)" (Funding Opportunity Number PAR 14 065) is a National Institutes of Health (NIH) discretionary grant program designed to support ancillary research projects that make use of archived biospecimens collected during selected type 1 diabetes clinical trials and related clinical studies. The central idea is to unlock additional scientific value from existing, well-characterized collections of samples by enabling investigators to ask new questions that were not fully addressed in the original trials. Rather than funding new sample collection efforts, the program focuses on analyses of stored specimens, leveraging the depth of associated clinical data from those completed or ongoing studies to produce insights that can move the field forward efficiently.
Projects proposed under this FOA are expected to drive meaningful discoveries about type 1 diabetes, particularly in areas tied to disease mechanisms and outcomes. NIH emphasizes research aimed at understanding primary pathogenesis (the underlying biological and immunological processes that lead to the onset and progression of type 1 diabetes) as well as the pathogenesis of complications (how and why diabetes-related complications develop over time). A major priority is also the identification and validation of biomarkers, including biomarkers that predict disease progression, stratify risk, or explain differences in clinical responses to interventions tested in the original trials. In practical terms, competitive applications would typically propose rigorous laboratory, molecular, immunologic, genetic, proteomic, metabolomic, or other advanced analytic approaches, using the archived samples to connect biological signals with well-documented clinical phenotypes and outcomes.
The mechanism used is the DP3 grant mechanism, and the opportunity is categorized under the broader funding activity area of Food and Nutrition/Health. NIH anticipated making around four awards, with an estimated total funding level of approximately $3,000,000. There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving the award. The opportunity was posted on January 7, 2014, with an original and current closing date of April 10, 2014, and it was archived on May 11, 2014, indicating it was a time-limited call with a specific submission window.
Eligibility is broad and intentionally inclusive, spanning a wide range of organization types. Eligible applicants include public and private institutions of higher education, public and state-controlled universities, private universities, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and multiple levels of government entities such as state, county, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly includes tribal entities and tribally controlled institutions, including federally recognized Native American tribal governments, other tribal organizations, and Tribally Controlled Colleges and Universities (TCCUs). In addition, it recognizes and encourages participation by a variety of mission-driven and capacity-building institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Asian American Native American Pacific Islander-serving institutions (AANAPISIs), and faith-based or community-based organizations.
A notable feature of this opportunity is that it allows non-U.S. participation. Non-domestic (non-U.S.) entities and foreign institutions are eligible to apply, and non-domestic components of U.S. organizations may also participate. Foreign components are allowed as defined by the NIH Grants Policy Statement. This openness reflects NIH interest in attracting the strongest possible scientific proposals and expertise, especially for specialized biosample analyses that may require unique technologies, cohorts for comparison, or advanced analytic capacity that exists globally.
Administratively, the FOA is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning it with NIH support for diabetes-related research. The full announcement was made available through the NIH Grants Guide (link provided in the source material). For access or technical issues related to the online announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), indicating that inquiries in this listing are geared toward electronic access and linking problems rather than scientific programmatic questions.
Overall, this grant opportunity is best understood as a targeted call to maximize the scientific return on investment from major type 1 diabetes clinical studies by enabling new, hypothesis-driven or discovery-oriented investigations using existing archived biospecimens. The expected outcome is actionable biological insight into disease mechanisms, complications, and biomarker development that can inform future research directions, improve prediction and monitoring, and help explain variable patient responses to interventions tested in prior trials.
Frequently Asked Questions (FAQs)
What is the "Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3)" funding opportunity?
This opportunity (Funding Opportunity Number PAR 14 065) is a National Institutes of Health (NIH) discretionary grant program that supports ancillary research projects using archived biospecimens collected during selected type 1 diabetes clinical trials and related clinical studies. The goal is to generate new scientific insights from existing, well-characterized sample collections rather than funding new sample collection.
What is the main purpose of this program?
The program is designed to unlock additional scientific value from stored biospecimens and their associated clinical data by enabling investigators to ask new questions that were not fully addressed in the original trials. It aims to efficiently advance the field by leveraging completed or ongoing studies with well-documented clinical phenotypes and outcomes.
What types of research does NIH expect or prioritize under this FOA?
Projects are expected to drive meaningful discoveries in type 1 diabetes, especially in:
- Primary pathogenesis (biological and immunological processes leading to onset and progression of type 1 diabetes)
- Pathogenesis of complications (how and why diabetes-related complications develop over time)
- Identification and validation of biomarkers (including markers that predict progression, stratify risk, or explain differences in clinical response to interventions)
Does this opportunity fund new biospecimen collection?
No. The focus is on analyses of stored (archived) biospecimens collected previously during selected type 1 diabetes clinical trials and related clinical studies. The intent is to leverage existing collections and the depth of associated clinical data.
What kinds of analytic approaches are considered relevant for competitive applications?
Competitive applications would typically propose rigorous analyses such as laboratory, molecular, immunologic, genetic, proteomic, metabolomic, or other advanced analytic approaches. A key feature is connecting biological signals from archived samples to well-documented clinical phenotypes and outcomes from the original studies.
What grant mechanism is used for this program?
The funding mechanism is the NIH DP3 grant mechanism.
What is the general funding category or activity area for this opportunity?
The opportunity is categorized under the broader funding activity area of Food and Nutrition/Health.
How many awards did NIH expect to make, and what was the anticipated total funding level?
NIH anticipated making around four awards, with an estimated total funding level of approximately $3,000,000.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement for this opportunity.
What are the key dates for this FOA?
- Posted date: January 7, 2014
- Original and current closing date: April 10, 2014
- Archive date: May 11, 2014
What does it mean that the opportunity was archived?
It indicates the FOA was time-limited with a specific submission window, and that the announcement is no longer active for new submissions under that call.
Who is eligible to apply?
Eligibility is broad and includes many organization types, including:
- Public and private institutions of higher education
- Public and state-controlled universities
- Private universities
- Nonprofit organizations (with or without 501(c)(3) status)
- For-profit organizations (including small businesses and other for-profits)
- State, county, city, or township governments
- Special district governments
- Independent school districts
- Public housing authorities / Indian housing authorities
- Federally recognized Native American tribal governments and other tribal organizations
- Tribally Controlled Colleges and Universities (TCCUs)
Are specific institution types encouraged or explicitly included?
Yes. The FOA explicitly recognizes and encourages participation from a range of mission-driven and capacity-building institutions and organizations, including:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving institutions
- Alaska Native and Native Hawaiian-serving institutions
- Asian American Native American Pacific Islander-serving institutions (AANAPISIs)
- Faith-based or community-based organizations
Are non-U.S. (foreign) organizations allowed to apply?
Yes. Non-domestic (non-U.S.) entities and foreign institutions are eligible to apply, and non-domestic components of U.S. organizations may also participate. Foreign components are allowed as defined by the NIH Grants Policy Statement.
Why does the FOA allow foreign participation?
The FOA reflects NIH interest in attracting the strongest scientific proposals and expertise, including specialized biosample analyses that may require unique technologies, comparative cohorts, or advanced analytic capabilities that exist globally.
What is the CFDA number associated with this FOA, and what does it correspond to?
The FOA is associated with CFDA number 93.847, which corresponds to Diabetes, Digestive, and Kidney Diseases Extramural Research.
Where was the full announcement published?
The full announcement was made available through the NIH Grants Guide (as referenced in the source material).
Who should be contacted for access or technical issues with the online announcement?
For access or technical issues related to the online announcement (such as electronic access and linking problems), the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact intended for scientific or programmatic questions?
No. Based on the information provided, the listed contact is for electronic access and linking problems rather than scientific or programmatic questions.
What is the overall expected outcome of projects funded under this FOA?
The expected outcome is actionable biological insight into type 1 diabetes mechanisms, complications, and biomarker development. This includes improving prediction and monitoring and helping explain variable patient responses to interventions tested in prior trials, while maximizing return on investment from major clinical studies.
Browse more opportunities from the same agency: National Institutes of Health
Browse more opportunities from the same category: Food and Nutrition Health
Next opportunity: Internship Program at HAFE
Previous opportunity: Strengthening Public Health Capacity in Bangladesh
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PAR 14 065
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PAR 14 065) also looked into and applied for these:
| Funding Opportunity |
|---|
| Cystic Fibrosis Research and Translation Core Center (P30) Apply for RFA DK 13 007 Funding Number: RFA DK 13 007 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Systems for Health Apply for RFA 641 14 00002 Funding Number: RFA 641 14 00002 Agency: Ghana USAID Accra Category: Food and Nutrition Health Funding Amount: $68,000,000 |
| Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) (U01) Apply for RFA DK 14 501 Funding Number: RFA DK 14 501 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $400,000 |
| Limited Competition Continuation of the Type 2 Diabetes in Adolescents and Youth (TODAY) Study (U01) Apply for RFA DK 14 502 Funding Number: RFA DK 14 502 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $10,000,000 |
| Accelerating Medicines Partnership (AMP) in Type 2 Diabetes (U01) Apply for RFA DK 14 003 Funding Number: RFA DK 14 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $300,000 |
| Limited Competition for the Data Coordinating Center of Accelerating Medicines Partnership (AMP) in Type 2 Diabetes (U01) Apply for RFA DK 14 503 Funding Number: RFA DK 14 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,500,000 |
| Reagents for Glucagon and Incretin Research (R41/R42) Apply for PA 14 204 Funding Number: PA 14 204 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Reagents for Glucagon and Incretin Research (R43/R44) Apply for RFA DK 14 008 Funding Number: RFA DK 14 008 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Diabetes Impact Award Closed Loop Technologies Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3) Apply for RFA DK 14 014 Funding Number: RFA DK 14 014 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Diabetes Impact Award Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3) Apply for RFA DK 14 015 Funding Number: RFA DK 14 015 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Nutrition Obesity Research Centers (NORCs) (P30) Apply for RFA DK 14 002 Funding Number: RFA DK 14 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30) Apply for RFA DK 14 012 Funding Number: RFA DK 14 012 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Increasing the Quality and Efficiency of Clinical Trials (R18) Apply for RFA FD 14 017 Funding Number: RFA FD 14 017 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $7,500,000 |
| U.S. India Bilateral Collaborative Research Partnerships (CRP) on Diabetes Research (R21) Apply for RFA DK 14 006 Funding Number: RFA DK 14 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $275,000 |
| Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30) Apply for RFA DK 14 013 Funding Number: RFA DK 14 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3) Apply for PAR 14 257 Funding Number: PAR 14 257 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $4,000,000 |
| Research Using Subjects From Selected Type 1 Diabetes Clinical Studies (Living Biobank) (DP3) Apply for PAR 14 258 Funding Number: PAR 14 258 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $7,000,000 |
| Chronic Kidney Disease Biomarkers Consortium (CKD BioCon) (U01) Apply for RFA DK 14 011 Funding Number: RFA DK 14 011 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| Improving Diabetes Management in Young Children with Type 1 Diabetes (DP3) Apply for RFA DK 14 022 Funding Number: RFA DK 14 022 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Critical Path Public Private Partnerships Apply for RFA FD 14 089 Funding Number: RFA FD 14 089 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $10,500,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PAR 14 065", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.