Opportunity Information: Apply for RFA AI 16 040
Apply for RFA AI 16 040
- The HHS-NIH11 in the education, health, income security and social services sector is offering a public funding opportunity titled "Revision Applications for U.S-South Africa Program for Collaborative Biomedical Research (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396, 93.399, 93.855, 93.856, 93.865,.
- This funding opportunity was created on May 11, 2016 and posted on May 11, 2016.
- Applicants must submit their applications by Aug 02, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The grant opportunity titled "Revision Applications for U.S.-South Africa Program for Collaborative Biomedical Research (U01)" (Funding Opportunity Number RFA AI 16 040) is a U.S. National Institutes of Health (NIH) funding announcement designed to support revision applications to existing cooperative agreement awards under the broader U.S.-South Africa Program for Collaborative Biomedical Research. In practical terms, this is not a brand-new standalone research program; it is aimed at expanding or strengthening specific, already-funded activities by allowing current awardees to request additional support through a formal revision. The overall intent is to deepen and broaden U.S.-South Africa collaboration in priority biomedical areas while building research capacity and participation among scientists who have been historically underrepresented in these collaborations.
A central goal of the revision is to increase the number of underrepresented scientists engaged in collaborative research activities. For the purposes of this specific FOA, "underrepresented scientists" are defined explicitly as Black South Africans based at South African historically disadvantaged institutions (HDIs) as well as other Universities of Technology. The emphasis is therefore both demographic and institutional: the program is structured to widen meaningful involvement from groups and institutions that have had less access to major international research networks, infrastructure, and funding streams. The revisions are meant to expand participation in ways that contribute directly to active research collaborations rather than simply offering general training without a strong research integration component.
The scientific focus areas highlighted in the announcement are tuberculosis (TB), HIV/AIDS biomedical science, HIV/AIDS behavioral science, and HIV-related co-morbidities, including malignancies. This framing signals that NIH is looking for projects that align with major infectious disease priorities in South Africa and globally, while also recognizing the complex clinical and public health realities of HIV, including co-occurring conditions such as cancers and other malignancies. The inclusion of behavioral science alongside biomedical research indicates that proposals can address not only mechanisms of disease and clinical interventions but also human behavior, adherence, prevention strategies, and health systems factors that influence real-world outcomes.
From an administrative standpoint, the funding mechanism is a Cooperative Agreement (U01), which typically means there is substantial involvement from NIH staff in the conduct and oversight of the project compared with a standard research project grant. Cooperative agreements often involve coordinated milestones, collaborative governance, or programmatic input from the funding agency, which fits the cross-national partnership model and the goal of deliberately expanding participation by targeted groups. The opportunity is listed under the U.S. Department of Health and Human Services, National Institutes of Health (Agency name shown as HHS-NIH11), and it is categorized as discretionary funding with activity categories spanning education, health, and related social service domains, reflecting its combined research and capacity-building aims.
The FOA was created and posted on May 11, 2016, with an application closing date of August 2, 2016 (the original and current closing dates are the same in the source data). The announcement references multiple CFDA numbers (93.396, 93.399, 93.855, 93.856, 93.865), which indicates alignment with several NIH program authorities or institutes/centers that may be supporting the initiative. The eligibility field is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)," which usually signals that eligibility is constrained by the revision nature of the application and the underlying parent award requirements, rather than being open to any applicant without an existing qualifying grant.
In short, this FOA supports targeted expansions to existing U.S.-South Africa collaborative research projects, using the U01 cooperative agreement structure, with a strong emphasis on bringing more Black South African scientists from HDIs and Universities of Technology into active, collaborative TB and HIV-related research, including work on HIV-associated co-morbidities such as malignancies. The revisions are intended to grow participation and strengthen collaborative research capacity in priority disease areas through deliberate inclusion and partnership-building within the context of ongoing NIH-supported collaborations.
FAQs: Revision Applications for U.S.-South Africa Program for Collaborative Biomedical Research (U01)
What is the title of this grant opportunity?
The opportunity is titled "Revision Applications for U.S.-South Africa Program for Collaborative Biomedical Research (U01)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA AI 16 040.
Who is the funding agency?
The funding agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH). The agency name is shown as HHS-NIH11.
What type of funding mechanism is used for this opportunity?
This opportunity uses a Cooperative Agreement (U01) mechanism. A U01 typically involves substantial NIH staff involvement in the conduct and oversight of the project compared with a standard research project grant.
Is this a new, standalone research program?
No. This funding announcement is designed to support revision applications to existing cooperative agreement awards under the broader U.S.-South Africa Program for Collaborative Biomedical Research. In practice, it is meant to expand or strengthen specific activities that are already funded, rather than launching brand-new standalone projects.
What is a "revision application" in the context of this FOA?
In this FOA, a revision application is a formal request for additional support to expand or strengthen specific, already-funded activities under an existing cooperative agreement award within the broader U.S.-South Africa collaborative program.
What is the overall purpose of the revisions supported by this FOA?
The overall intent is to deepen and broaden U.S.-South Africa collaboration in priority biomedical areas while building research capacity and increasing participation among scientists who have been historically underrepresented in these collaborations.
What is a central goal of the revision applications?
A central goal is to increase the number of underrepresented scientists engaged in collaborative research activities, specifically within the active U.S.-South Africa research collaborations supported by NIH.
How does this FOA define "underrepresented scientists"?
For the purposes of this specific FOA, "underrepresented scientists" are defined explicitly as Black South Africans based at South African historically disadvantaged institutions (HDIs), as well as other Universities of Technology.
Which institutions are emphasized for expanding participation?
The FOA emphasizes South African historically disadvantaged institutions (HDIs) and other Universities of Technology as key institutional settings for expanding participation by underrepresented scientists.
Does the FOA focus only on training activities?
No. The revisions are meant to expand participation in ways that contribute directly to active research collaborations. The emphasis is not on general training by itself, but on meaningful involvement that is strongly integrated with ongoing collaborative research activities.
What scientific focus areas are highlighted?
The highlighted scientific focus areas are tuberculosis (TB), HIV/AIDS biomedical science, HIV/AIDS behavioral science, and HIV-related co-morbidities, including malignancies.
Are behavioral science projects included, or only biomedical research?
Behavioral science is explicitly included. The FOA highlights HIV/AIDS behavioral science alongside biomedical science, indicating that proposals may address behavioral factors, adherence, prevention strategies, and other real-world factors that influence outcomes.
What does the FOA mean by HIV-related co-morbidities, including malignancies?
The FOA recognizes that HIV is often associated with additional health conditions. It specifically includes HIV-related co-morbidities and notes malignancies (such as cancers) as an example within the co-morbidity scope.
How does the U01 cooperative agreement structure relate to this program?
The U01 structure generally involves coordinated milestones, collaborative governance, or programmatic input from NIH, which aligns with cross-national partnership work and the FOA's goal of deliberately expanding participation from targeted groups and institutions.
How is this opportunity categorized in terms of funding type and activity areas?
It is categorized as discretionary funding. The activity categories span education, health, and related social service domains, reflecting combined research and capacity-building aims.
When was the FOA posted?
The FOA was created and posted on May 11, 2016.
What is the application closing date?
The application closing date is August 2, 2016. The source data indicates the original and current closing dates are the same.
What CFDA numbers are associated with this opportunity?
The FOA references multiple CFDA numbers: 93.396, 93.399, 93.855, 93.856, and 93.865.
What does it mean that multiple CFDA numbers are listed?
The presence of multiple CFDA numbers suggests the opportunity aligns with several NIH program authorities or NIH institutes/centers that may be supporting the initiative.
Who is eligible to apply?
The eligibility field is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)." Based on the FOA description, eligibility is typically constrained by the revision nature of the application and the underlying parent award requirements, rather than being broadly open to any applicant without an existing qualifying award.
Is this opportunity open to applicants without an existing NIH-supported cooperative agreement in this program?
The FOA is specifically designed for revision applications to existing cooperative agreement awards under the broader U.S.-South Africa Program for Collaborative Biomedical Research, which implies it is intended for current awardees seeking additional support through a revision.
What kind of collaboration is this FOA designed to strengthen?
It is designed to strengthen U.S.-South Africa collaborative biomedical research, with an explicit intent to deepen and broaden partnerships in TB and HIV-related priority areas while expanding participation by underrepresented South African scientists and institutions.
What is the practical emphasis of the revisions supported by this FOA?
The practical emphasis is on targeted expansions to existing U.S.-South Africa collaborative research projects, using the U01 cooperative agreement structure, to grow participation and strengthen collaborative research capacity in priority disease areas through deliberate inclusion and partnership-building.
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| Funding Opportunity |
|---|
| Revision Applications for U.S-South Africa Program for Collaborative Biomedical Research (R01) Apply for RFA AI 16 039 Funding Number: RFA AI 16 039 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Building Interdisciplinary Research Careers in Women's Health (K12) Apply for RFA OD 16 013 Funding Number: RFA OD 16 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $500,000 |
| BRAIN Initiative: Foundations of Non-Invasive Functional Human Brain Imaging and Recording - Bridging Scales and Modalities (R01) Apply for RFA MH 17 235 Funding Number: RFA MH 17 235 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $700,000 |
| BRAIN Initiative: New Concepts and Early-Stage Research for Large-Scale Recording and Modulation in the Nervous System (R21) Apply for RFA EY 17 001 Funding Number: RFA EY 17 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| BRAIN Initiative: Exploratory Targeted BRAIN Circuits Projects - eTargetedBCP (R21) Apply for RFA NS 17 015 Funding Number: RFA NS 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp) Apply for PA 17 098 Funding Number: PA 17 098 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $100,000 |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01) Apply for RFA NS 18 008 Funding Number: RFA NS 18 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01) Apply for RFA NS 18 010 Funding Number: RFA NS 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trial Not Allowed) Apply for RFA NS 18 029 Funding Number: RFA NS 18 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Required) Apply for RFA NS 19 002 Funding Number: RFA NS 19 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed) Apply for RFA NS 19 003 Funding Number: RFA NS 19 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Back Pain Consortium (BACPAC) Research Program: Phase 2 Clinical Trials (UG3/UH3 Clinical Trial Required) Apply for RFA AR 19 029 Funding Number: RFA AR 19 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| HEAL Initiative: Coordinating Center to Support NIDA Preventing Opioid Use Disorder in Older Adolescents and Young Adults (ages 1630) Initiative (U24 Clinical Trial Not Allowed) Apply for RFA DA 19 034 Funding Number: RFA DA 19 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Medical Rehabilitation Research Resource (P2C Clinical Trial Optional) Apply for RFA HD 20 004 Funding Number: RFA HD 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Data Analysis, Informatics and Resource Center (U24 Clinical Trial Not Allowed) Apply for RFA DA 20 003 Funding Number: RFA DA 20 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA DA 20 004 Funding Number: RFA DA 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Linked Research Project Sites (Collaborative U01 Clinical Trial Not Allowed) Apply for RFA DA 20 002 Funding Number: RFA DA 20 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (U24 - Clinical Trial Required -Infrastructure) Apply for RFA OD 19 025 Funding Number: RFA OD 19 025 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) (UG3/UH3, Clinical Trials Optional) Apply for RFA AT 20 004 Funding Number: RFA AT 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional) Apply for RFA NS 20 029 Funding Number: RFA NS 20 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
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