Opportunity Information: Apply for CDC RFA TP16 1602

  • The HHS-CDC-OPHPR in the health sector is offering a public funding opportunity titled "Public Health Preparedness and Response (PHPR) Cooperative Agreement for All-Hazards Public Health Emergencies: Zika 2016" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.069.
  • This funding opportunity was created on May 11, 2016 and posted on May 11, 2016.
  • Applicants must submit their applications by Jun 13, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $5,000,000.00 in funding.
  • The number of recipients for this funding is limited to 53 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA TP16 1602

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Opportunity Summary:

The Public Health Preparedness and Response (PHPR) Cooperative Agreement for All-Hazards Public Health Emergencies: Zika 2016 (Funding Opportunity Number CDC RFA TP16 1602) was a discretionary cooperative agreement issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (HHS-CDC-OPHPR). It was designed to rapidly strengthen public health readiness for a potential outbreak of Zika virus disease (ZVD) in the continental United States, Hawaii, U.S. territories, and freely associated states. The core idea behind the opportunity was to pair CDC guidance and hands-on technical support with targeted funding so that health departments could close immediate preparedness gaps and be ready to move quickly if local transmission occurred or expanded.

CDC announced a total of 25 million dollars to be distributed across 53 state, territorial, and local health departments. The selection and distribution approach was tied to the conditions at the time of the announcement, including where Zika transmission was already occurring, which jurisdictions were most likely to be affected next, and what historical patterns of arboviral disease (mosquito-borne viruses) suggested about risk. Individual awards could be as high as 5,000,000 dollars (award ceiling), reflecting the expectation that some jurisdictions would need more intensive capacity-building due to higher risk, larger populations, or more complex operational needs. Applications were due June 13, 2016, with the funding opportunity posted and created on May 11, 2016. The CFDA number associated with the program was 93.069, and eligible applicants included state governments, county governments, city or township governments, and other entities as clarified in the full eligibility guidance.

Because this was a cooperative agreement, the relationship was not simply a pass-through grant where recipients operate independently. Cooperative agreements typically involve substantial federal involvement, meaning CDC would actively provide direction, coordination, and technical assistance as jurisdictions refined plans, tested response functions, and aligned their efforts with national guidance. The funding was explicitly meant to accelerate preparedness planning and operational readiness rather than to duplicate work already supported under other federal awards. A key restriction was that funds could not be used for activities already covered by other federal grants or cooperative agreements, which pushed recipients to focus on unmet needs, overlooked operational details, and short-term readiness improvements that could make the difference during a fast-moving public health event.

The expected outcomes emphasized practical, operational deliverables rather than broad or theoretical planning. A major priority was further refinement of jurisdictional Zika response plans, including identifying gaps and ensuring coordinated planning with CDCs Epidemiology and Laboratory Capacity (ELC) for Infectious Diseases cooperative agreement activities. In practice, this meant health departments were expected to sharpen how they would detect cases, manage data, coordinate lab testing capacity, and integrate epidemiology and laboratory functions so that surveillance and confirmation could happen quickly and reliably. The opportunity also called for establishing jurisdictional incident management teams specifically for Zika response, including clear points of contact for the U.S. Pregnancy Registry, reflecting the serious maternal and infant health consequences associated with Zika and the need for tight coordination around pregnancy-related monitoring and follow-up.

Another prominent outcome area was exercising response plan components, which signals that CDC wanted jurisdictions to do more than write plans. Exercises, whether tabletop or functional, are used to reveal weak handoffs, unclear roles, missing authorities, and logistical bottlenecks before a real incident forces systems to perform under pressure. Closely tied to operational readiness was the development of risk communication plans and culturally appropriate messaging to inform the public about ZVD risks and protective measures. That focus on cultural appropriateness matters in outbreak settings because messaging has to reach diverse communities with different languages, trust levels, media habits, and risk perceptions, especially when prevention involves personal behaviors like mosquito avoidance, sexual transmission prevention, and pregnancy-related decision-making.

The program also expected jurisdictions to identify and organize resources across several response pillars: human surveillance, vector surveillance and control, and maternal-child health services, including comprehensive services for families impacted by ZVD. This reflects the reality that a Zika response is not only about finding infections; it also involves monitoring mosquito populations and implementing vector control strategies, while simultaneously ensuring that pregnant people, infants, and families have access to coordinated clinical referrals, supportive services, and long-term follow-up when needed. On the administrative side, recipients were expected to implement preparedness guidelines that enable rapid execution of service contracts, which is a practical but often underestimated requirement during emergencies. The ability to quickly activate contracts for services, supplies, or specialized support can determine whether a response scales in days versus weeks.

Finally, the funding opportunity highlighted the provision of public health emergency management expertise and coordination across all areas of the response. The intent was to address operational gaps, synchronize jurisdictional resources, and align activities with other federal funding streams without duplicating them. In other words, this opportunity aimed to create a more integrated, mission-ready posture where health departments could manage incident command functions, surveillance and lab coordination, communications, vector control, and maternal-child health activities in a unified way, supported by CDC technical assistance and consistent national guidance.

Frequently Asked Questions (FAQs)

What is the PHPR Cooperative Agreement for All-Hazards Public Health Emergencies: Zika 2016?

It was a discretionary cooperative agreement issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (HHS-CDC-OPHPR). The opportunity focused on rapidly strengthening public health readiness for a potential outbreak of Zika virus disease (ZVD), pairing CDC guidance and hands-on technical support with targeted funding to close immediate preparedness gaps.

What is the funding opportunity number for this award?

The funding opportunity number was CDC RFA TP16 1602.

Who issued this funding opportunity?

The opportunity was issued by HHS-CDC-OPHPR (U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Office of Public Health Preparedness and Response).

What geographic areas were the focus of this Zika preparedness funding?

The program was designed to support readiness in the continental United States, Hawaii, U.S. territories, and freely associated states, particularly where local Zika transmission could occur or expand.

How much total funding was announced?

CDC announced a total of 25,000,000 dollars to be distributed across 53 state, territorial, and local health departments.

What was the maximum award amount (award ceiling)?

Individual awards could be as high as 5,000,000 dollars.

How was funding selection and distribution determined?

Selection and distribution were tied to conditions at the time of the announcement, including where Zika transmission was already occurring, which jurisdictions were most likely to be affected next, and what historical patterns of arboviral disease suggested about risk.

Who was eligible to apply?

Eligible applicants included state governments, county governments, city or township governments, and other entities as clarified in the full eligibility guidance.

What CFDA number was associated with this program?

The CFDA number associated with this program was 93.069.

When was the opportunity posted and created?

The funding opportunity was posted and created on May 11, 2016.

When were applications due?

Applications were due June 13, 2016.

What does it mean that this award was a cooperative agreement?

A cooperative agreement is not a simple pass-through grant. It typically includes substantial federal involvement. In this case, CDC would actively provide direction, coordination, and technical assistance as jurisdictions refined plans, tested response functions, and aligned their work with national guidance.

What was the main purpose of the funding?

The main purpose was to accelerate preparedness planning and operational readiness for Zika virus disease, helping jurisdictions close immediate gaps so they could move quickly if local transmission occurred or expanded.

Were recipients expected to produce practical deliverables or broad planning documents?

The expected outcomes emphasized practical, operational deliverables. The focus was on readiness improvements that could be executed during a fast-moving public health event, not broad or theoretical planning alone.

What were the plan-related expectations for funded jurisdictions?

Jurisdictions were expected to further refine their Zika response plans, identify gaps, and ensure coordinated planning with CDC's Epidemiology and Laboratory Capacity (ELC) for Infectious Diseases cooperative agreement activities.

How did this opportunity connect to epidemiology and laboratory capacity work?

The opportunity emphasized coordination with ELC-related activities so that surveillance and confirmation could happen quickly and reliably, including clear integration between epidemiology functions and laboratory testing capacity.

Were jurisdictions expected to establish incident management teams for Zika?

Yes. The opportunity called for establishing jurisdictional incident management teams specifically for Zika response.

What is the significance of the U.S. Pregnancy Registry in this funding opportunity?

The opportunity expected jurisdictions to designate clear points of contact for the U.S. Pregnancy Registry, reflecting the maternal and infant health consequences associated with Zika and the need for tight coordination around pregnancy-related monitoring and follow-up.

Did the program require exercising response plans?

Yes. A prominent outcome area was exercising response plan components, signaling that jurisdictions were expected to test plans (such as through tabletop or functional exercises) to uncover weak handoffs, unclear roles, missing authorities, and logistical bottlenecks.

What were the expectations related to risk communication?

Jurisdictions were expected to develop risk communication plans and culturally appropriate messaging to inform the public about Zika virus disease risks and protective measures.

Why did the opportunity emphasize culturally appropriate messaging?

Because outbreak messaging must reach diverse communities with different languages, trust levels, media habits, and risk perceptions, especially when prevention involves personal behaviors such as mosquito avoidance, sexual transmission prevention, and pregnancy-related decision-making.

What response areas (pillars) were jurisdictions expected to organize resources around?

The opportunity expected jurisdictions to identify and organize resources across human surveillance, vector surveillance and control, and maternal-child health services, including comprehensive services for families impacted by Zika virus disease.

Was vector surveillance and control included as a funded focus area?

Yes. The program explicitly included vector surveillance and control as a response pillar, reflecting the mosquito-borne nature of Zika.

What maternal and child health activities were highlighted?

The opportunity highlighted maternal-child health services and comprehensive services for families impacted by Zika, aligning response operations with pregnancy-related monitoring, referrals, supportive services, and follow-up needs.

Did the opportunity include administrative readiness requirements?

Yes. Recipients were expected to implement preparedness guidelines that enable rapid execution of service contracts, recognizing that the ability to quickly activate contracts can materially affect response speed and scale.

What kinds of operational gaps was this funding intended to address?

The funding was intended to address unmet preparedness needs and overlooked operational details that could limit a rapid response, including incident management coordination, surveillance and lab integration, communications readiness, vector control coordination, and maternal-child health response alignment.

Were there restrictions on using these funds alongside other federal awards?

Yes. A key restriction was that funds could not be used for activities already covered by other federal grants or cooperative agreements. The intent was to avoid duplication and focus on short-term, unmet readiness improvements.

How was CDC expected to support recipients during the period of performance?

CDC support was described as guidance and hands-on technical support, including active direction, coordination, and technical assistance to help jurisdictions refine plans, test response functions, and align with national guidance.

What was the overarching goal of the opportunity?

The overarching goal was to create a more integrated, mission-ready posture so health departments could manage incident command functions, surveillance and lab coordination, communications, vector control, and maternal-child health activities in a unified way, supported by CDC technical assistance and consistent guidance.

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