Opportunity Information: Apply for PAR 13 170
Apply for PAR 13 170
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394 Cancer Detection and Diagnosis Research.
- This funding opportunity was created on Apr 11, 2013 and posted on Apr 11, 2013.
- Applicants must submit their applications by Jul 10, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: County governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments State governments City or township governments Independent school districts Small businesses Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The NIH funding opportunity PAR-13-170, titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)," supports competing revision applications to existing, currently funded NIH P50 Program Project Grants. Rather than funding brand-new centers, this announcement is specifically for teams that already hold an active P50 award and want to add new work that meaningfully expands the overall scope of the parent program project. The central scientific emphasis is on improving detection of pathogen-induced cancers by studying how cancer-causing infectious agents interact with the human microbiome and with host biology, with the goal of identifying measurable signals that can be used for risk assessment and earlier diagnosis.
From a research focus standpoint, the FOA is aimed at the biology that connects carcinogenic pathogens, host responses, and microbial community dynamics to cancer initiation and progression. It encourages projects that investigate molecular signatures linked to (1) risk of developing pathogen-induced cancer, (2) early detection of these cancers, and (3) chronic inflammation that can drive progression toward invasive disease. In practical terms, this points to studies that may characterize microbial, host, or combined host-microbe biomarkers; examine immune and inflammatory pathways; and define detectable molecular patterns that appear before overt malignancy or during early, potentially more treatable stages. A key requirement is that the proposed work in the revision must be structured as an additional project that expands the parent P50 as a whole, not a minor supplement or a disconnected add-on.
Administratively, this is a discretionary grant opportunity issued by the National Institutes of Health under the Funding Activity Category of Education/Health and aligned with CFDA 93.394 (Cancer Detection and Diagnosis Research). Cost sharing or matching is not required. The opportunity was posted on April 11, 2013, with an application closing date of July 10, 2013, and it was archived on August 10, 2013. The listed award ceiling is $150,000, indicating the revision mechanism here is intended to provide a defined amount of additional support to extend an existing P50 program with a new, scope-expanding project focused on DPIC-related aims.
Eligibility is broad in terms of organizational types, but it is constrained by the mechanism: only organizations that already have an active NIH P50 program project award can submit a competing revision under this FOA. Eligible applicant types include a wide range of U.S.-based institutions and organizations such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (excluding small business limitations only in the sense that for-profits other than small businesses are explicitly listed while small businesses are also listed), and multiple levels of government entities (state, county, city/township, special districts), as well as tribal governments and tribal organizations and public housing authorities/Indian housing authorities. The FOA also clarifies that several institution categories are included as eligible (for example, HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, Alaska Native and Native Hawaiian-serving institutions), as well as faith-based or community-based organizations and certain federal agencies. Foreign institutions are not eligible, and foreign components are not allowed; non-U.S. components of U.S. organizations are also not eligible, consistent with NIH foreign component policy limitations stated in the announcement.
Overall, PAR-13-170 is best understood as a targeted opportunity for established NIH P50 program project teams to add a new research project that strengthens their center-like program around detection of pathogen-induced cancers. The NIH is signaling particular interest in integrative studies that link pathogen biology, microbiome context, and host responses to actionable molecular signatures for risk stratification and early cancer detection, including signatures related to chronic inflammation that may precede or promote invasive disease. For full details and official instructions, the announcement points applicants to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/pa-files/PAR-13-170.html) and provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.
Frequently Asked Questions (FAQs): NIH PAR-13-170 (P50) - Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC)
1) What is PAR-13-170?
PAR-13-170 is an NIH funding opportunity announcement (FOA) titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)." It supports competing revision applications to existing, currently funded NIH P50 Program Project Grants, with a scientific emphasis on improving detection of pathogen-induced cancers.
2) Is this FOA for starting a brand-new P50 center or program?
No. This FOA is not intended to fund brand-new centers. It is specifically for groups that already hold an active NIH P50 award and want to propose new work that expands the overall scope of the parent P50 program project.
3) What type of application does this FOA support?
This FOA supports competing revision applications to existing NIH P50 Program Project Grants. The revision is meant to add an additional project that meaningfully expands the parent P50 as a whole.
4) What is the main scientific goal of the opportunity?
The main scientific goal is to improve detection of pathogen-induced cancers by studying how cancer-causing infectious agents interact with the human microbiome and with host biology, with the aim of identifying measurable signals that can be used for risk assessment and earlier diagnosis.
5) What research themes does the FOA emphasize?
The FOA emphasizes biology that connects carcinogenic pathogens, host responses, and microbial community dynamics to cancer initiation and progression. It encourages integrative studies that link pathogen biology, microbiome context, and host responses to actionable molecular signatures.
6) What kinds of molecular signatures or outcomes are of interest?
The FOA encourages projects that investigate molecular signatures linked to: (1) risk of developing pathogen-induced cancer, (2) early detection of pathogen-induced cancers, and (3) chronic inflammation that can drive progression toward invasive disease.
7) Does the FOA encourage biomarker-related research?
Yes. The description points toward studies that may characterize microbial biomarkers, host biomarkers, or combined host-microbe biomarkers, including detectable molecular patterns that appear before overt malignancy or during early stages of disease.
8) Is research on immune or inflammatory pathways relevant under this FOA?
Yes. The FOA encourages work that examines immune and inflammatory pathways, especially where chronic inflammation may precede or promote progression toward invasive disease, and where measurable signals may support risk stratification or early detection.
9) What does the FOA require in terms of how the revision is structured?
A key requirement is that the revision be structured as an additional project that expands the overall scope of the parent P50 program project. It should not be a minor supplement or a disconnected add-on.
10) What is the funding activity category and CFDA listing?
This is a discretionary NIH grant opportunity under the Funding Activity Category of Education/Health and aligned with CFDA 93.394 (Cancer Detection and Diagnosis Research).
11) Is cost sharing or matching required?
No. Cost sharing or matching is not required for this opportunity.
12) What is the award ceiling listed for this FOA?
The listed award ceiling is $150,000, indicating a defined amount of additional support intended to extend an existing P50 program with a new scope-expanding project focused on DPIC-related aims.
13) When was PAR-13-170 posted, and what were the key dates?
The opportunity was posted on April 11, 2013. The application closing date was July 10, 2013. The FOA was archived on August 10, 2013.
14) Who is eligible to apply?
Eligibility is constrained by the mechanism: only organizations that already have an active NIH P50 Program Project Grant can submit a competing revision application under this FOA.
15) What types of organizations are listed as eligible applicant organizations?
The FOA lists a wide range of eligible U.S.-based organizations, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and for-profits other than small businesses), and multiple levels of government entities (state, county, city/township, special districts), as well as tribal governments and tribal organizations and public housing authorities/Indian housing authorities.
16) Are minority-serving institutions and certain specialized institution types included?
Yes. The FOA clarifies that multiple institution categories are included as eligible, such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, and Alaska Native and Native Hawaiian-serving institutions, among others.
17) Are faith-based or community-based organizations included as eligible applicants?
Yes. The FOA explicitly includes faith-based or community-based organizations among eligible applicant types (subject to the overarching requirement that the applicant already holds an active NIH P50 award).
18) Are foreign institutions eligible?
No. Foreign institutions are not eligible under this FOA.
19) Are foreign components or non-U.S. components allowed?
No. Foreign components are not allowed, and non-U.S. components of U.S. organizations are also not eligible, consistent with the NIH foreign component policy limitations stated in the announcement.
20) Where can applicants find the official FOA and instructions?
The FOA points applicants to the NIH Grants Guide page: http://grants.nih.gov/grants/guide/pa-files/PAR-13-170.html. It also provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 13 170) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revisions to P01 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P01) Apply for PAR 13 171 Funding Number: PAR 13 171 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Paul Calabresi Career Development Award for Clinical Oncology (K12) Apply for PAR 13 201 Funding Number: PAR 13 201 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Symptom Management in HIV Infected Individuals with Comorbid Conditions (R01) Apply for PA 13 210 Funding Number: PA 13 210 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Symptom Management in HIV Infected Individuals with Comorbid Conditions (R21) Apply for PA 13 211 Funding Number: PA 13 211 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Innovative Measurement Tools for Community Engaged Research Efforts (R01) Apply for PA 13 209 Funding Number: PA 13 209 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Innovative Measurement Tools for Community Engaged Research Efforts (R21) Apply for PA 13 212 Funding Number: PA 13 212 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Limited Competition Fogarty HIV Research Training Program for Low and Middle Income Country Institutions (D43) Apply for PAR 13 126 Funding Number: PAR 13 126 Agency: National Institutes of Health Category: Education Health Funding Amount: $282,000 |
| Medications Development Centers of Excellence Cooperative Program (U54) Apply for RFA DA 14 004 Funding Number: RFA DA 14 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| Substance Use Disorders and Molecular Regulation of Brain Energy Utilization (R01) Apply for RFA DA 14 005 Funding Number: RFA DA 14 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $350,000 |
| Substance Use Disorders and Molecular Regulation of Brain Energy Utilization (R21) Apply for RFA DA 14 006 Funding Number: RFA DA 14 006 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Integration and Analysis of Diverse HIV Associated Data (R03) Apply for RFA MH 14 200 Funding Number: RFA MH 14 200 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NIDA Research Center of Excellence Grant Program (P50) Apply for PAR 13 222 Funding Number: PAR 13 222 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| FY14 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1) Apply for RFA DA 14 008 Funding Number: RFA DA 14 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Integrating Substance Abuse Prevention and Treatment within HIV/AIDS Service Delivery Settings (R01) Apply for RFA DA 14 011 Funding Number: RFA DA 14 011 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| HIV/AIDS and Substance Use among Black/African American Women and Young MSM (R01) Apply for RFA DA 14 010 Funding Number: RFA DA 14 010 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV/AIDS and Substance Use Among the Homeless and Unstably Housed (R01) Apply for RFA DA 14 009 Funding Number: RFA DA 14 009 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Comorbid HIV, Chronic Pain, and Substance Use among Older Adults (R21) Apply for RFA DA 14 012 Funding Number: RFA DA 14 012 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research to Characterize and Reduce Stigma to Improve Health (R21) Apply for PA 13 246 Funding Number: PA 13 246 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research to Characterize and Reduce Stigma to Improve Health (R03) Apply for PA 13 247 Funding Number: PA 13 247 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Research to Characterize and Reduce Stigma to Improve Health (R01) Apply for PA 13 248 Funding Number: PA 13 248 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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