Opportunity Information: Apply for PAR 13 171
Apply for PAR 13 171
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Revisions to P01 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394 Cancer Detection and Diagnosis Research.
- This funding opportunity was created on Apr 11, 2013 and posted on Apr 11, 2013.
- Applicants must submit their applications by Jul 10, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Small businesses City or township governments Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts County governments State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
PAR-13-171, titled "Revisions to P01 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P01)," is a National Institutes of Health (NIH) funding opportunity that supports competing revision applications to already-funded NIH P01 Program Project grants. In practical terms, it is not a stand-alone P01 competition for brand-new program projects; it is specifically designed for teams that currently hold an active P01 and want to expand that parent award with an added research component. The intent is to fund a new research project that meaningfully extends the scope of the existing program project, rather than simply continuing or modestly modifying what is already underway.
The scientific focus of this FOA is detection of pathogen-induced cancer (DPIC), with a strong emphasis on how carcinogenic pathogens interact with both the human microbiome and the host. The announcement encourages research aimed at identifying and validating molecular signatures that can indicate cancer risk or enable earlier detection in settings where infection-driven mechanisms are involved. It also highlights chronic inflammation as a key biological context, specifically encouraging studies that connect inflammatory processes to the progression from infection or precancerous states to invasive cancer. Overall, the opportunity is oriented toward biomarker and signature discovery or refinement, and toward mechanistic and translational work that could improve early detection strategies for cancers with known or suspected infectious origins.
Applications submitted under this FOA must be framed as revisions (formerly called competing revisions) and must correspond to a new research project within the existing P01 structure. That means the proposed work should be a discrete, well-justified expansion that fits the program project model, aligns with the parent grant’s overall theme, and adds capabilities or directions that were not previously supported under the original award. The programmatic expectation is that the revision will strengthen the overall P01 by bringing in new aims related to pathogen-host-microbiome interactions and detection-relevant molecular signals tied to infection-associated carcinogenesis and inflammation-driven progression.
From an administrative standpoint, the opportunity is categorized as discretionary grant funding and is associated with CFDA 93.394 (Cancer Detection and Diagnosis Research). Cost sharing or matching is not required. The FOA was posted on April 11, 2013, with an original and current closing date of July 10, 2013, and an archive date of August 10, 2013. The listed award ceiling is $150,000, indicating an upper limit on the amount available under the revision mechanism for the proposed expansion.
Eligibility is broad across U.S.-based organizations and governmental entities, including public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), small businesses, for-profit entities (other than small businesses), and a range of state, local, and tribal government bodies and related organizations. The FOA also explicitly recognizes a variety of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISI institutions, among others. At the same time, it clearly excludes non-U.S. (foreign) institutions and foreign components of U.S. organizations, and it does not allow foreign components as defined by the NIH Grants Policy Statement.
The sponsoring agency is the NIH, and the full announcement is available via the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-13-171.html. For access or linking issues, the contact point listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is PAR-13-171?
PAR-13-171 is an NIH funding opportunity titled "Revisions to P01 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P01)." It supports competing revision applications (i.e., revisions) to already-funded NIH P01 Program Project grants, specifically to add a new research project component focused on detection of pathogen-induced cancer.
Is this a funding opportunity for brand-new P01 Program Project grants?
No. This is not a stand-alone competition for new P01 program projects. It is intended only for teams that already have an active NIH P01 award and want to expand that parent award through a competing revision.
What kind of application does NIH expect under this FOA?
Applications must be submitted as revisions (competing revisions). The proposed work must be framed as an expansion to an existing, already-funded P01, not as a continuation of the same scope or a modest modification of what is already supported.
What is the main purpose of the revision being requested?
The purpose is to support a discrete, well-justified new research project that meaningfully extends the scope of the existing P01 program project by adding new capabilities or research directions aligned with the FOA's scientific focus.
Does the revision need to fit within the existing P01 structure?
Yes. The new work must correspond to a new research project within the existing P01 structure and align with the overall theme of the parent program project grant.
What scientific area does this FOA focus on?
The FOA focuses on detection of pathogen-induced cancer (DPIC), emphasizing how carcinogenic pathogens interact with the human microbiome and the host, and how those interactions relate to cancer risk and early detection.
What types of research topics are encouraged?
The announcement encourages research aimed at identifying and validating molecular signatures that indicate cancer risk or enable earlier detection in infection-driven settings, as well as mechanistic and translational work that could improve early detection strategies for cancers with known or suspected infectious origins.
How important is the microbiome-host-pathogen relationship in the proposed work?
It is a major emphasis. The FOA specifically highlights research on interactions among carcinogenic pathogens, the human microbiome, and the host as part of the scientific focus for detection-related advances.
Does the FOA emphasize biomarker discovery?
Yes. The opportunity is oriented toward biomarker and molecular signature discovery, validation, or refinement, particularly as they relate to infection-associated carcinogenesis and early detection.
Is chronic inflammation relevant to the scope of this FOA?
Yes. Chronic inflammation is highlighted as a key biological context. The FOA encourages studies that connect inflammatory processes to progression from infection or precancerous states to invasive cancer.
What makes a proposed revision "meaningful" under this FOA?
Based on the description, a meaningful revision is a discrete new research project that expands the parent P01's scope and strengthens the overall program project by adding new aims related to pathogen-host-microbiome interactions and detection-relevant molecular signals tied to infection-associated cancer and inflammation-driven progression.
What is the maximum award amount mentioned for this opportunity?
The listed award ceiling is $150,000, which indicates an upper limit on the amount available under the revision mechanism for the proposed expansion.
Is cost sharing or matching required?
No. Cost sharing or matching is not required for this funding opportunity.
What is the CFDA number associated with this FOA?
The opportunity is associated with CFDA 93.394, Cancer Detection and Diagnosis Research.
What type of funding is this categorized as?
It is categorized as discretionary grant funding.
When was this FOA posted?
The FOA was posted on April 11, 2013.
What was the closing date for applications?
The listed original and current closing date is July 10, 2013.
When was the FOA archived?
The archive date is August 10, 2013.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and governmental entities, including public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), small businesses, for-profit entities (other than small businesses), and state, local, and tribal governments and related organizations.
Are certain institution types explicitly recognized as eligible?
Yes. The FOA explicitly recognizes multiple institution types, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISI institutions, among others.
Are foreign institutions allowed to apply?
No. The FOA excludes non-U.S. (foreign) institutions.
Are foreign components of U.S. organizations allowed?
No. The FOA does not allow foreign components of U.S. organizations, as defined by the NIH Grants Policy Statement.
Which agency sponsors this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Where can the full announcement be found?
The full announcement is available in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-13-171.html.
Who should be contacted for access or linking issues with the announcement?
For access or linking issues, the listed contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Browse more opportunities from the same category: Education Health
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Previous opportunity: Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)
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| Research to Characterize and Reduce Stigma to Improve Health (R03) Apply for PA 13 247 Funding Number: PA 13 247 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
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| Limited Competition Adult Brain Tumor Consortium (ABTC) (UM1) Apply for RFA CA 13 501 Funding Number: RFA CA 13 501 Agency: National Institutes of Health Category: Education Health Funding Amount: $2,000,000 |
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