Opportunity Information: Apply for PA 13 191
Apply for PA 13 191
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Apr 11, 2013 and posted on Apr 11, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Small businesses Public and State controlled institutions of higher education County governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01)" (Funding Opportunity Number PA 13-191) is a National Institutes of Health (NIH) discretionary funding announcement that supports research using the R01 mechanism. Its central purpose is to fund studies that test whether structural interventions can reduce HIV/AIDS transmission risk by changing the conditions, settings, and broader environment in which alcohol use happens. The focus is not limited to individual behavior change programs; instead, it emphasizes interventions that operate at the community, organizational, policy, or environmental level, where alcohol availability, alcohol-serving contexts, and alcohol-related norms can shape sexual risk and other pathways tied to HIV transmission. The announcement highlights that structural and environmental approaches have already shown success in reducing various alcohol-related harms, but that comparable work explicitly linking these approaches to HIV/AIDS risk reduction is still emerging, and more rigorous research is needed to build the evidence base.
This opportunity sits within NIH health research priorities and is associated with CFDA number 93.273 (Alcohol Research Programs). It does not require cost sharing or matching, which can lower barriers for applicants that may not have access to non-federal funds. The announcement was originally posted on April 11, 2013, with a closing date of May 7, 2016, and it was archived on June 7, 2016. While the dates indicate it is no longer open, the content is still useful as a reference point for understanding NIH interests in the intersection of alcohol environments and HIV risk, and for shaping similar proposals under newer opportunities.
In practical terms, the research encouraged by this FOA centers on interventions that modify upstream drivers of risk rather than relying solely on counseling or education aimed at individuals. Structural interventions can include changes to alcohol policies, enforcement practices, alcohol outlet density or operating practices, venue-based management strategies, pricing and availability strategies, or other community-level modifications that influence when, where, and how alcohol is consumed. The underlying rationale is that alcohol use can increase vulnerability to HIV transmission through multiple pathways, including impaired judgment, increased likelihood of condomless sex, heightened exposure to coercion or violence, and participation in higher-risk sexual networks that may be concentrated in certain drinking settings. By changing the alcohol-use environment itself, structural interventions aim to reduce these conditions at scale and produce broader population-level prevention benefits.
Eligibility for this R01 opportunity was broad and inclusive across many organizational types. Eligible applicants included small businesses and other for-profit organizations (other than small businesses), nonprofits with and without 501(c)(3) status, public and private institutions of higher education, independent school districts, and a wide range of governmental entities such as city or township governments, county governments, state governments, special district governments, and public housing authorities/Indian housing authorities. Tribal eligibility was also explicit, covering federally recognized tribal governments and other tribal organizations. The FOA also recognized a number of mission-driven and capacity-building institution types as eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based and community-based organizations and eligible federal agencies.
Notably, the announcement allowed participation from outside the United States. Non-U.S. entities (foreign organizations and foreign institutions) were eligible to apply, non-U.S. components of U.S. organizations were eligible, and foreign components (as defined by the NIH Grants Policy Statement) were allowed. This matters because alcohol-related HIV risks often have strong regional and cultural dimensions, and structural interventions may need to be tested in diverse legal, economic, and social contexts to understand what works, why it works, and how it can be adapted.
From an applicant standpoint, the most important takeaway is that NIH was looking for rigorous, effectiveness-focused research that can demonstrate whether changing alcohol-related environments leads to measurable reductions in HIV transmission risk. That typically implies stronger study designs, clear definitions of the structural lever being changed, credible measurement of both alcohol-environment outcomes and HIV-related risk outcomes, and attention to real-world implementation factors like feasibility, sustainability, enforcement, and unintended consequences. The announcement also signals that the field was still developing, which often means NIH is receptive to well-justified, theory-driven approaches that fill clear evidence gaps and improve the scientific understanding of how structural alcohol interventions connect to HIV prevention.
For additional official details, the archived announcement was linked through NIH at: http://grants.nih.gov/grants/guide/pa-files/PA-13-191.html. For technical issues accessing the announcement or linking problems, NIH listed the Office of Extramural Research (OER) Webmaster contact at FBOWebmaster@OD.NIH.GOV.
FAQs: Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01) - PA 13-191
What is the title and funding opportunity number for this grant?
The opportunity is titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01)" and the Funding Opportunity Number (FOA) is PA 13-191.
What agency offered this opportunity?
This was a discretionary funding announcement from the National Institutes of Health (NIH).
What grant mechanism does this opportunity use?
The announcement supports research using the NIH R01 mechanism.
What is the central purpose of the FOA?
The FOA aims to fund studies that test whether structural interventions can reduce HIV/AIDS transmission risk by changing the conditions, settings, and broader environment in which alcohol use occurs.
What does the FOA mean by "structural interventions" in this context?
Structural interventions are approaches that operate at the community, organizational, policy, or environmental level rather than focusing only on individual behavior change. They target upstream drivers of risk by modifying the alcohol-use environment itself.
Is this FOA focused on individual-level counseling or education programs?
No. The emphasis is not limited to individual behavior change programs. The priority is on interventions that change alcohol availability, alcohol-serving contexts, and alcohol-related norms at broader levels (community, organizational, policy, or environmental).
What kinds of interventions were encouraged under this FOA?
Examples mentioned include changes to alcohol policies, enforcement practices, alcohol outlet density or operating practices, venue-based management strategies, pricing and availability strategies, and other community-level modifications that influence when, where, and how alcohol is consumed.
How is alcohol use connected to HIV transmission risk according to the FOA?
The FOA notes multiple pathways: impaired judgment, increased likelihood of condomless sex, heightened exposure to coercion or violence, and participation in higher-risk sexual networks that may be concentrated in certain drinking settings.
Why does NIH emphasize changing the alcohol-use environment?
The rationale is that changing the environment can reduce risk conditions at scale and potentially produce broader population-level prevention benefits, rather than relying only on interventions aimed at individuals.
What does the FOA say about the evidence base for these approaches?
It highlights that structural and environmental approaches have already shown success in reducing various alcohol-related harms, but that rigorous research explicitly linking these approaches to HIV/AIDS risk reduction was still emerging and needed to be strengthened.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA number 93.273 (Alcohol Research Programs).
Is cost sharing or matching required?
No. The announcement states that it does not require cost sharing or matching.
When was the opportunity posted, and when did it close?
It was originally posted on April 11, 2013, with a closing date of May 7, 2016.
Is this FOA currently open for applications?
No. The FOA was archived on June 7, 2016, and the provided dates indicate it is no longer open.
If the FOA is archived, why might it still be useful?
The content can still serve as a reference for understanding NIH interests at the intersection of alcohol environments and HIV risk, and for shaping similar proposals under newer opportunities.
What types of applicants were eligible to apply?
Eligibility was broad. It included small businesses, other for-profit organizations (other than small businesses), nonprofits with and without 501(c)(3) status, public and private higher education institutions, independent school districts, and many governmental entities (city/township, county, state, special district governments, and public housing authorities/Indian housing authorities).
Were tribal governments and tribal organizations eligible?
Yes. The FOA explicitly includes federally recognized tribal governments and other tribal organizations.
Did the FOA encourage applications from specific institution types (capacity-building or mission-driven institutions)?
Yes. The FOA recognized eligibility for Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), and also included faith-based and community-based organizations and eligible federal agencies.
Were non-U.S. (foreign) organizations allowed to apply?
Yes. Non-U.S. entities (foreign organizations and foreign institutions) were eligible to apply.
Could non-U.S. components of U.S. organizations participate?
Yes. Non-U.S. components of U.S. organizations were eligible.
Were "foreign components" allowed under this FOA?
Yes. Foreign components (as defined by the NIH Grants Policy Statement) were allowed.
What kind of research approach was NIH looking for?
The FOA emphasizes rigorous, effectiveness-focused research designed to show whether changing alcohol-related environments leads to measurable reductions in HIV transmission risk.
What does "rigorous, effectiveness-focused" imply for study design and measurement?
Based on the FOA language, it implies clear definition of the structural lever being changed, credible measurement of alcohol-environment outcomes and HIV-related risk outcomes, and attention to real-world implementation factors such as feasibility, sustainability, enforcement, and unintended consequences.
Where can applicants find the official archived announcement?
The archived NIH announcement is available at: http://grants.nih.gov/grants/guide/pa-files/PA-13-191.html
Who is listed as a contact for technical issues accessing the announcement?
NIH listed the Office of Extramural Research (OER) Webmaster for technical issues: FBOWebmaster@OD.NIH.GOV
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